DK108495C - Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof. - Google Patents
Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof.Info
- Publication number
- DK108495C DK108495C DK626764A DK626764A DK108495C DK 108495 C DK108495 C DK 108495C DK 626764 A DK626764 A DK 626764A DK 626764 A DK626764 A DK 626764A DK 108495 C DK108495 C DK 108495C
- Authority
- DK
- Denmark
- Prior art keywords
- benzomorphans
- substituted
- preparation
- acid addition
- addition salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Discharge Lamp (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33229663A | 1963-12-20 | 1963-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK108495C true DK108495C (en) | 1967-12-27 |
Family
ID=23297612
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK429865A DK108497C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof. |
| DK626864A DK106552C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans. |
| DK429765A DK108496C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof. |
| DK626764A DK108495C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof. |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK429865A DK108497C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof. |
| DK626864A DK106552C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans. |
| DK429765A DK108496C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof. |
Country Status (12)
| Country | Link |
|---|---|
| AT (4) | AT249277B (en) |
| BE (2) | BE657405A (en) |
| CH (7) | CH449643A (en) |
| DE (2) | DE1445853A1 (en) |
| DK (4) | DK108497C (en) |
| ES (4) | ES307300A1 (en) |
| FR (2) | FR4345M (en) |
| GB (2) | GB1077711A (en) |
| IL (2) | IL22642A (en) |
| NL (3) | NL6414820A (en) |
| NO (2) | NO119273B (en) |
| SE (2) | SE322779B (en) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| EP2987788A1 (en) | 2002-05-17 | 2016-02-24 | Taiwanj Pharmaceuticals Co., Ltd. | Opioid and opioid-like compounds and uses thereof |
| US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| JP5486928B2 (en) | 2007-02-26 | 2014-05-07 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Cyclic urea and carbamate inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| JP5451611B2 (en) | 2007-07-26 | 2014-03-26 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1 |
| AR069207A1 (en) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | CYCLIC UREAS AS INHIBITORS OF THE 11 BETA - HIDROXI-ESTEROIDE DESHIDROGENASA 1 |
| CA2704628C (en) | 2007-11-16 | 2016-11-29 | Boehringer Ingelheim International Gmbh | Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| WO2009075835A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceutical, Inc | CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1 |
| TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| JP5490020B2 (en) | 2008-01-24 | 2014-05-14 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| JP5734666B2 (en) | 2008-02-11 | 2015-06-17 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | 1,3-oxaazepan-2-one and 1,3-diazepan-2-one inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| US20110028445A1 (en) * | 2008-02-12 | 2011-02-03 | Boehringer Ingelheim International Gmbh | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| US8598160B2 (en) | 2008-02-15 | 2013-12-03 | Vitae Pharmaceuticals, Inc. | Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| JP5538365B2 (en) | 2008-05-01 | 2014-07-02 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1 |
| US8242111B2 (en) | 2008-05-01 | 2012-08-14 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| CL2009001058A1 (en) | 2008-05-01 | 2010-09-10 | Vitae Pharmaceuticals Inc | Compounds derived from substituted oxazines, inhibitors of 11b-hydroxysteroid dehydrogenase type-1; pharmaceutical composition; and use of the compound to inhibit the activity of 11b-hsd1, as in the treatment of diabetes, dyslipidemia, hypertension, obesity, cancer, glaucoma, among others. |
| PL2300461T3 (en) | 2008-05-01 | 2013-09-30 | Vitae Pharmaceuticals Inc | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8765780B2 (en) | 2008-05-13 | 2014-07-01 | Boehringer Ingelheim International Gmbh | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
| CA2729998A1 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| EP2687525B1 (en) | 2008-07-25 | 2015-09-23 | Boehringer Ingelheim International GmbH | Cyclic inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| WO2010046445A2 (en) | 2008-10-23 | 2010-04-29 | Boehringer Ingelheim International Gmbh | Urea derivatives of substituted nortropanes, medicaments containing such compounds and their use |
| WO2010089303A1 (en) | 2009-02-04 | 2010-08-12 | Boehringer Ingelheim International Gmbh | CYCLIC INHIBITORS OF 11 β-HYDROXYSTEROID DEHYDROGENASE 1 |
| UA109255C2 (en) | 2009-04-30 | 2015-08-10 | Берінгер Інгельхайм Інтернешнл Гмбх | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| WO2010139673A1 (en) | 2009-06-02 | 2010-12-09 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8927539B2 (en) | 2009-06-11 | 2015-01-06 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure |
| EP2448928B1 (en) | 2009-07-01 | 2014-08-13 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| AR078887A1 (en) | 2009-11-06 | 2011-12-07 | Boehringer Ingelheim Int | ARILO AND HETEROARILCARBONILO DERIVATIVES OF HEXAHYDROINDENOPIRIDINE AND OCTAHYDROBENZOQUINOLINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| JP5860042B2 (en) | 2010-06-16 | 2016-02-16 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Substituted 5, 6 and 7 membered heterocycles, medicaments containing such compounds and their use |
| WO2011161128A1 (en) | 2010-06-25 | 2011-12-29 | Boehringer Ingelheim International Gmbh | Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders |
| WO2012059416A1 (en) | 2010-11-02 | 2012-05-10 | Boehringer Ingelheim International Gmbh | Pharmaceutical combinations for the treatment of metabolic disorders |
| TWI537258B (en) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline |
| JP2014524438A (en) | 2011-08-17 | 2014-09-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Indenopyridine derivatives |
-
0
- NL NL127995D patent/NL127995C/xx active
-
1964
- 1964-11-30 CH CH1619167A patent/CH449643A/en unknown
- 1964-11-30 CH CH1538464A patent/CH446371A/en unknown
- 1964-11-30 CH CH1618967A patent/CH449641A/en unknown
- 1964-11-30 CH CH1618767A patent/CH449639A/en unknown
- 1964-11-30 CH CH1538364A patent/CH448118A/en unknown
- 1964-11-30 CH CH1618867A patent/CH449640A/en unknown
- 1964-11-30 CH CH1619067A patent/CH449642A/en unknown
- 1964-12-18 GB GB5149864A patent/GB1077711A/en not_active Expired
- 1964-12-18 AT AT392965A patent/AT249277B/en active
- 1964-12-18 AT AT1074364A patent/AT253687B/en active
- 1964-12-18 IL IL2264264A patent/IL22642A/en unknown
- 1964-12-18 DE DE19641445853 patent/DE1445853A1/en active Pending
- 1964-12-18 SE SE1536064A patent/SE322779B/xx unknown
- 1964-12-18 AT AT1074264A patent/AT261126B/en active
- 1964-12-18 SE SE1536164A patent/SE305657B/xx unknown
- 1964-12-18 GB GB5150064A patent/GB1092394A/en not_active Expired
- 1964-12-18 IL IL2264364A patent/IL22643A/en unknown
- 1964-12-18 DE DE19641445854 patent/DE1445854A1/en active Pending
- 1964-12-18 NL NL6414820A patent/NL6414820A/xx unknown
- 1964-12-18 NL NL6414821A patent/NL6414821A/xx unknown
- 1964-12-18 AT AT392865A patent/AT249276B/en active
- 1964-12-19 DK DK429865A patent/DK108497C/en active
- 1964-12-19 DK DK626864A patent/DK106552C/en active
- 1964-12-19 DK DK429765A patent/DK108496C/en active
- 1964-12-19 ES ES0307300A patent/ES307300A1/en not_active Expired
- 1964-12-19 NO NO15606264A patent/NO119273B/no unknown
- 1964-12-19 ES ES0307302A patent/ES307302A1/en not_active Expired
- 1964-12-19 ES ES0307301A patent/ES307301A1/en not_active Expired
- 1964-12-19 ES ES0307299A patent/ES307299A1/en not_active Expired
- 1964-12-19 DK DK626764A patent/DK108495C/en active
- 1964-12-19 NO NO15606364A patent/NO119274B/no unknown
- 1964-12-21 BE BE657405D patent/BE657405A/xx unknown
- 1964-12-21 BE BE657406D patent/BE657406A/xx unknown
-
1965
- 1965-03-19 FR FR9865A patent/FR4345M/fr active Active
- 1965-03-19 FR FR9866A patent/FR4346M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DE1445854A1 (en) | 1968-12-05 |
| AT249277B (en) | 1966-09-12 |
| ES307301A1 (en) | 1965-05-16 |
| GB1092394A (en) | 1967-11-22 |
| CH448118A (en) | 1967-12-15 |
| NL6414820A (en) | 1965-06-21 |
| DK108496C (en) | 1967-12-27 |
| ES307302A1 (en) | 1965-05-16 |
| DK108497C (en) | 1967-12-27 |
| CH449640A (en) | 1968-01-15 |
| SE305657B (en) | 1968-11-04 |
| AT253687B (en) | 1967-04-25 |
| GB1077711A (en) | 1967-08-02 |
| NO119274B (en) | 1970-04-27 |
| ES307299A1 (en) | 1965-05-16 |
| DK106552C (en) | 1967-02-20 |
| SE322779B (en) | 1970-04-20 |
| BE657405A (en) | 1965-06-21 |
| IL22643A (en) | 1968-07-25 |
| IL22642A (en) | 1968-07-25 |
| AT249276B (en) | 1966-09-12 |
| NO119273B (en) | 1970-04-27 |
| NL127995C (en) | |
| BE657406A (en) | 1965-06-21 |
| NL6414821A (en) | 1965-06-21 |
| CH449639A (en) | 1968-01-15 |
| FR4345M (en) | 1966-08-16 |
| CH449642A (en) | 1968-01-15 |
| DE1445853A1 (en) | 1968-12-05 |
| CH449643A (en) | 1968-01-15 |
| FR4346M (en) | 1966-08-16 |
| CH449641A (en) | 1968-01-15 |
| AT261126B (en) | 1968-04-10 |
| CH446371A (en) | 1967-11-15 |
| ES307300A1 (en) | 1965-05-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK108496C (en) | Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof. | |
| DK108972C (en) | Process for the preparation of lipoylpyridoxamine or acid addition salts thereof. | |
| DK125421B (en) | Analogous process for the preparation of 5-substituted-aza-dibenzo-cycloheptenes or acid addition salts thereof. | |
| DK106797C (en) | Process for the preparation of 3-hydroxy-5-aminomethyl-isoxazole or acid addition salts thereof. | |
| DK116000B (en) | Process for the preparation of amino-halo-benzylamines or acid addition salts thereof. | |
| DK117000B (en) | Process for the preparation of substituted phenylamino-1,3-diazacyclopentenes (2) or acid addition salts thereof. | |
| DK115851B (en) | Process for the preparation of 1,2-dihydro-4-aryl-quinazolines or acid addition salts thereof. | |
| DK112872B (en) | Process for the preparation of [1,2-α] -imidazopyridines or acid addition salts thereof. | |
| DK107942C (en) | Process for the preparation of 1,5-disubstituted 3-aza-1-pentanols or acid addition salts thereof. | |
| DK108394C (en) | Process for the preparation of substituted imidazo- or pyrimido-quinazolines or acid addition salts thereof. | |
| DK125552B (en) | Process for the preparation of 1,2,3,4-tetrahydroisoquinoline-2-carboxamidines or acid addition salts thereof. | |
| DK121604B (en) | Process for the preparation of substituted iminocycloheptatriene derivatives or acid addition salts thereof. | |
| DK106381C (en) | Process for the preparation of 2-dimethylamino-3,5,6-trimethylpyrazine or acid addition salts thereof. | |
| DK112449B (en) | Process for the preparation of 2,3-dihydro-5-pyridyl-1H-1,4-benzodiazepines or acid addition salts thereof. | |
| DK111893B (en) | Process for the preparation of substituted methylhydrazines or acid addition salts thereof. | |
| DK105649C (en) | Process for the preparation of 2-dimethylaminopyrazine or acid addition salts thereof. | |
| DK106092C (en) | Process for the preparation of basic substituted 11-alkyl-5,6-dihydro-6-oxo-morphanthridines or acid addition salts thereof. | |
| DK118667B (en) | Process for the preparation of 1,3,4,5-tetrahydro-5-phenyl-2H-1,4-benzodiazepin-2-ones or acid addition salts thereof. | |
| DK118345B (en) | Process for the preparation of 2,5-diacylamino-3,6-diamino-1,4-dihydroxybenzenes or acid addition salts thereof. | |
| DK106144C (en) | Process for the preparation of aryl-N- (1,2,5,6-tetrahydro-1,3-dialkyl-4-pyridyl) -alkanoylamides or acid addition salts thereof. | |
| DK107170C (en) | Process for the preparation of 10-monoalkylaminoalkyl-10,11-dihydro-11-oxo-5H-dibenzo (b, e) (1,4) diazepines or acid addition salts thereof. | |
| DK108857C (en) | Process for the preparation of phenylcyclohexylalkylamines or acid addition salts thereof. | |
| DK112530B (en) | Process for the preparation of α-phenyl-β-tetrahydofuryl-2-propionitriles or acid addition salts thereof. | |
| DK118241B (en) | Process for the preparation of 2-amino-oxazolines or acid addition salts thereof. | |
| DK106911C (en) | Process for the preparation of 2,3-dihydro-5-aryl-1H-1,4-benzodiazepine derivatives or acid addition salts thereof. |