CH449643A - Process for the preparation of new substituted 6,7-benzomorphans - Google Patents
Process for the preparation of new substituted 6,7-benzomorphansInfo
- Publication number
- CH449643A CH449643A CH1619167A CH1619167A CH449643A CH 449643 A CH449643 A CH 449643A CH 1619167 A CH1619167 A CH 1619167A CH 1619167 A CH1619167 A CH 1619167A CH 449643 A CH449643 A CH 449643A
- Authority
- CH
- Switzerland
- Prior art keywords
- benzomorphans
- preparation
- new substituted
- substituted
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33229663A | 1963-12-20 | 1963-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH449643A true CH449643A (en) | 1968-01-15 |
Family
ID=23297612
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1618867A CH449640A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1619067A CH449642A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1538364A CH448118A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1619167A CH449643A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1618767A CH449639A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1538464A CH446371A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1618967A CH449641A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1618867A CH449640A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1619067A CH449642A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1538364A CH448118A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1618767A CH449639A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1538464A CH446371A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1618967A CH449641A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
Country Status (12)
| Country | Link |
|---|---|
| AT (4) | AT249277B (en) |
| BE (2) | BE657405A (en) |
| CH (7) | CH449640A (en) |
| DE (2) | DE1445854A1 (en) |
| DK (4) | DK108497C (en) |
| ES (4) | ES307301A1 (en) |
| FR (2) | FR4346M (en) |
| GB (2) | GB1092394A (en) |
| IL (2) | IL22643A (en) |
| NL (3) | NL6414820A (en) |
| NO (2) | NO119274B (en) |
| SE (2) | SE322779B (en) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| WO2003097608A2 (en) | 2002-05-17 | 2003-11-27 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US8835426B2 (en) | 2007-02-26 | 2014-09-16 | Vitae Pharmaceuticals, Inc. | Cyclic urea and carbamate inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| EP2183228B1 (en) | 2007-07-26 | 2014-08-20 | Vitae Pharmaceuticals, Inc. | CYCLIC INHIBITORS OF 11ß -HYDROXYSTERIOD DEHYDROGENASE 1 |
| AR069207A1 (en) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | CYCLIC UREAS AS INHIBITORS OF THE 11 BETA - HIDROXI-ESTEROIDE DESHIDROGENASA 1 |
| WO2009063061A2 (en) | 2007-11-16 | 2009-05-22 | Boehringer Ingelheim International Gmbh | Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| CA2708303A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
| TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| JP5490020B2 (en) | 2008-01-24 | 2014-05-14 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| WO2009102428A2 (en) | 2008-02-11 | 2009-08-20 | Vitae Pharmaceuticals, Inc. | 1,3-OXAZEPAN-2-ONE AND 1,3-DIAZEPAN-2-ONE INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE 1 |
| EP2245014B1 (en) * | 2008-02-12 | 2011-11-02 | Boehringer Ingelheim International GmbH | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| WO2009102460A2 (en) | 2008-02-15 | 2009-08-20 | Vitae Pharmaceuticals, Inc. | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| JP5301563B2 (en) | 2008-05-01 | 2013-09-25 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1 |
| CA2723039A1 (en) | 2008-05-01 | 2009-11-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| EP2291373B1 (en) | 2008-05-01 | 2013-09-11 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| EP2291370B1 (en) | 2008-05-01 | 2013-11-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| CA2724214A1 (en) | 2008-05-13 | 2009-11-19 | Boehringer Ingelheim International Gmbh | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
| TW201016691A (en) | 2008-07-25 | 2010-05-01 | Boehringer Ingelheim Int | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| NZ590495A (en) | 2008-07-25 | 2012-10-26 | Vitae Pharmaceuticals Inc | Dihydropyridin-phenyl-3-oxazinan-2-ones as inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| CA2738453C (en) | 2008-10-23 | 2017-07-04 | Boehringer Ingelheim International Gmbh | Urea derivatives of substituted nortropanes, medicaments containing such compounds and their use |
| CA2744946A1 (en) | 2009-02-04 | 2010-08-12 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
| UA109255C2 (en) | 2009-04-30 | 2015-08-10 | Берінгер Інгельхайм Інтернешнл Гмбх | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8703765B2 (en) | 2009-06-02 | 2014-04-22 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| WO2011011123A1 (en) | 2009-06-11 | 2011-01-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
| EP2448928B1 (en) | 2009-07-01 | 2014-08-13 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| TWI531571B (en) | 2009-11-06 | 2016-05-01 | 維它藥物公司 | Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline |
| US8933072B2 (en) | 2010-06-16 | 2015-01-13 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
| JP5813106B2 (en) | 2010-06-25 | 2015-11-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Azaspirohexanone as an inhibitor of 11-β-HSD1 for the treatment of metabolic disorders |
| CA2813671A1 (en) | 2010-11-02 | 2012-05-10 | Boehringer Ingelheim International Gmbh | Pharmaceutical combinations for the treatment of metabolic disorders |
| TWI537258B (en) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline |
| US8735585B2 (en) | 2011-08-17 | 2014-05-27 | Boehringer Ingelheim International Gmbh | Indenopyridine derivatives |
-
0
- NL NL127995D patent/NL127995C/xx active
-
1964
- 1964-11-30 CH CH1618867A patent/CH449640A/en unknown
- 1964-11-30 CH CH1619067A patent/CH449642A/en unknown
- 1964-11-30 CH CH1538364A patent/CH448118A/en unknown
- 1964-11-30 CH CH1619167A patent/CH449643A/en unknown
- 1964-11-30 CH CH1618767A patent/CH449639A/en unknown
- 1964-11-30 CH CH1538464A patent/CH446371A/en unknown
- 1964-11-30 CH CH1618967A patent/CH449641A/en unknown
- 1964-12-18 DE DE19641445854 patent/DE1445854A1/en active Pending
- 1964-12-18 SE SE1536064A patent/SE322779B/xx unknown
- 1964-12-18 DE DE19641445853 patent/DE1445853A1/en active Pending
- 1964-12-18 AT AT392965A patent/AT249277B/en active
- 1964-12-18 IL IL2264364A patent/IL22643A/en unknown
- 1964-12-18 NL NL6414820A patent/NL6414820A/xx unknown
- 1964-12-18 AT AT392865A patent/AT249276B/en active
- 1964-12-18 NL NL6414821A patent/NL6414821A/xx unknown
- 1964-12-18 GB GB5150064A patent/GB1092394A/en not_active Expired
- 1964-12-18 AT AT1074364A patent/AT253687B/en active
- 1964-12-18 AT AT1074264A patent/AT261126B/en active
- 1964-12-18 SE SE1536164A patent/SE305657B/xx unknown
- 1964-12-18 GB GB5149864A patent/GB1077711A/en not_active Expired
- 1964-12-18 IL IL2264264A patent/IL22642A/en unknown
- 1964-12-19 ES ES0307301A patent/ES307301A1/en not_active Expired
- 1964-12-19 ES ES0307300A patent/ES307300A1/en not_active Expired
- 1964-12-19 DK DK429865A patent/DK108497C/en active
- 1964-12-19 ES ES0307299A patent/ES307299A1/en not_active Expired
- 1964-12-19 NO NO15606364A patent/NO119274B/no unknown
- 1964-12-19 ES ES0307302A patent/ES307302A1/en not_active Expired
- 1964-12-19 DK DK626864A patent/DK106552C/en active
- 1964-12-19 DK DK626764A patent/DK108495C/en active
- 1964-12-19 DK DK429765A patent/DK108496C/en active
- 1964-12-19 NO NO15606264A patent/NO119273B/no unknown
- 1964-12-21 BE BE657405D patent/BE657405A/xx unknown
- 1964-12-21 BE BE657406D patent/BE657406A/xx unknown
-
1965
- 1965-03-19 FR FR9866A patent/FR4346M/fr active Active
- 1965-03-19 FR FR9865A patent/FR4345M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DK108495C (en) | 1967-12-27 |
| AT249277B (en) | 1966-09-12 |
| ES307301A1 (en) | 1965-05-16 |
| CH449640A (en) | 1968-01-15 |
| NL127995C (en) | |
| IL22642A (en) | 1968-07-25 |
| CH449641A (en) | 1968-01-15 |
| FR4346M (en) | 1966-08-16 |
| SE322779B (en) | 1970-04-20 |
| NL6414821A (en) | 1965-06-21 |
| FR4345M (en) | 1966-08-16 |
| IL22643A (en) | 1968-07-25 |
| NO119273B (en) | 1970-04-27 |
| DK108497C (en) | 1967-12-27 |
| SE305657B (en) | 1968-11-04 |
| DK108496C (en) | 1967-12-27 |
| GB1077711A (en) | 1967-08-02 |
| DE1445853A1 (en) | 1968-12-05 |
| NL6414820A (en) | 1965-06-21 |
| AT253687B (en) | 1967-04-25 |
| AT249276B (en) | 1966-09-12 |
| ES307300A1 (en) | 1965-05-01 |
| CH449639A (en) | 1968-01-15 |
| AT261126B (en) | 1968-04-10 |
| NO119274B (en) | 1970-04-27 |
| BE657405A (en) | 1965-06-21 |
| CH448118A (en) | 1967-12-15 |
| CH446371A (en) | 1967-11-15 |
| DK106552C (en) | 1967-02-20 |
| CH449642A (en) | 1968-01-15 |
| ES307302A1 (en) | 1965-05-16 |
| DE1445854A1 (en) | 1968-12-05 |
| ES307299A1 (en) | 1965-05-16 |
| GB1092394A (en) | 1967-11-22 |
| BE657406A (en) | 1965-06-21 |
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