CH449641A - Process for the preparation of new substituted 6,7-benzomorphans - Google Patents
Process for the preparation of new substituted 6,7-benzomorphansInfo
- Publication number
- CH449641A CH449641A CH1618967A CH1618967A CH449641A CH 449641 A CH449641 A CH 449641A CH 1618967 A CH1618967 A CH 1618967A CH 1618967 A CH1618967 A CH 1618967A CH 449641 A CH449641 A CH 449641A
- Authority
- CH
- Switzerland
- Prior art keywords
- benzomorphans
- preparation
- new substituted
- substituted
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Discharge Lamp (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33229663A | 1963-12-20 | 1963-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH449641A true CH449641A (en) | 1968-01-15 |
Family
ID=23297612
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1538464A CH446371A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1619167A CH449643A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1538364A CH448118A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1618967A CH449641A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1618867A CH449640A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1618767A CH449639A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1619067A CH449642A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1538464A CH446371A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1619167A CH449643A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1538364A CH448118A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1618867A CH449640A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1618767A CH449639A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
| CH1619067A CH449642A (en) | 1963-12-20 | 1964-11-30 | Process for the preparation of new substituted 6,7-benzomorphans |
Country Status (12)
| Country | Link |
|---|---|
| AT (4) | AT261126B (en) |
| BE (2) | BE657406A (en) |
| CH (7) | CH446371A (en) |
| DE (2) | DE1445853A1 (en) |
| DK (4) | DK106552C (en) |
| ES (4) | ES307299A1 (en) |
| FR (2) | FR4346M (en) |
| GB (2) | GB1092394A (en) |
| IL (2) | IL22642A (en) |
| NL (3) | NL6414820A (en) |
| NO (2) | NO119274B (en) |
| SE (2) | SE305657B (en) |
Families Citing this family (33)
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| US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| EP1506174B1 (en) | 2002-05-17 | 2015-09-30 | Taiwanj Pharmaceuticals Co., Ltd. | Use of naltrexone for treating kidney and liver damage |
| US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| EP2125750B1 (en) | 2007-02-26 | 2014-05-21 | Vitae Pharmaceuticals, Inc. | Cyclic urea and carbamate inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| JP5451611B2 (en) | 2007-07-26 | 2014-03-26 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1 |
| AR069207A1 (en) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | CYCLIC UREAS AS INHIBITORS OF THE 11 BETA - HIDROXI-ESTEROIDE DESHIDROGENASA 1 |
| JP5769970B2 (en) | 2007-11-16 | 2015-08-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Aryl- and heteroarylcarbonyl derivatives of benzomorphan and related skeletons, medicaments containing such compounds and their use |
| JP5490014B2 (en) | 2007-12-11 | 2014-05-14 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | 11β-hydroxysteroid dehydrogenase type 1 cyclic urea inhibitor |
| TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| WO2009094169A1 (en) | 2008-01-24 | 2009-07-30 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| JP5734666B2 (en) | 2008-02-11 | 2015-06-17 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | 1,3-oxaazepan-2-one and 1,3-diazepan-2-one inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| CA2711757C (en) * | 2008-02-12 | 2016-07-26 | Boehringer Ingelheim International Gmbh | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| EP2254872A2 (en) | 2008-02-15 | 2010-12-01 | Vitae Pharmaceuticals, Inc. | Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| US8569292B2 (en) | 2008-05-01 | 2013-10-29 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| JP5301563B2 (en) | 2008-05-01 | 2013-09-25 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1 |
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| EP2291370B1 (en) | 2008-05-01 | 2013-11-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| TW200950780A (en) | 2008-05-13 | 2009-12-16 | Boehringer Ingelheim Int | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
| JP5379160B2 (en) | 2008-07-25 | 2013-12-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1 |
| JP5777030B2 (en) | 2008-07-25 | 2015-09-09 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Inhibitor of 11β-hydroxysteroid dehydrogenase 1 |
| TW201022266A (en) | 2008-10-23 | 2010-06-16 | Boehringer Ingelheim Int | Urea derivatives of substituted nortropanes, medicaments containing such compounds and their use |
| EP2393807B1 (en) | 2009-02-04 | 2013-08-14 | Boehringer Ingelheim International GmbH | Cyclic inhibitors of 11 -hydroxysteroid dehydrogenase 1 |
| MA33216B1 (en) | 2009-04-30 | 2012-04-02 | Boehringer Ingelheim Int | CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 |
| JP5670440B2 (en) | 2009-06-02 | 2015-02-18 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1 |
| WO2011011123A1 (en) | 2009-06-11 | 2011-01-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
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| JP5813106B2 (en) | 2010-06-25 | 2015-11-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Azaspirohexanone as an inhibitor of 11-β-HSD1 for the treatment of metabolic disorders |
| AU2011325286B2 (en) | 2010-11-02 | 2015-04-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical combinations for the treatment of metabolic disorders |
| TWI537258B (en) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline |
| US8735585B2 (en) | 2011-08-17 | 2014-05-27 | Boehringer Ingelheim International Gmbh | Indenopyridine derivatives |
-
0
- NL NL127995D patent/NL127995C/xx active
-
1964
- 1964-11-30 CH CH1538464A patent/CH446371A/en unknown
- 1964-11-30 CH CH1619167A patent/CH449643A/en unknown
- 1964-11-30 CH CH1538364A patent/CH448118A/en unknown
- 1964-11-30 CH CH1618967A patent/CH449641A/en unknown
- 1964-11-30 CH CH1618867A patent/CH449640A/en unknown
- 1964-11-30 CH CH1618767A patent/CH449639A/en unknown
- 1964-11-30 CH CH1619067A patent/CH449642A/en unknown
- 1964-12-18 NL NL6414820A patent/NL6414820A/xx unknown
- 1964-12-18 AT AT1074264A patent/AT261126B/en active
- 1964-12-18 NL NL6414821A patent/NL6414821A/xx unknown
- 1964-12-18 GB GB5150064A patent/GB1092394A/en not_active Expired
- 1964-12-18 GB GB5149864A patent/GB1077711A/en not_active Expired
- 1964-12-18 DE DE19641445853 patent/DE1445853A1/en active Pending
- 1964-12-18 SE SE1536164A patent/SE305657B/xx unknown
- 1964-12-18 AT AT1074364A patent/AT253687B/en active
- 1964-12-18 DE DE19641445854 patent/DE1445854A1/en active Pending
- 1964-12-18 IL IL2264264A patent/IL22642A/en unknown
- 1964-12-18 AT AT392965A patent/AT249277B/en active
- 1964-12-18 AT AT392865A patent/AT249276B/en active
- 1964-12-18 IL IL2264364A patent/IL22643A/en unknown
- 1964-12-18 SE SE1536064A patent/SE322779B/xx unknown
- 1964-12-19 ES ES0307299A patent/ES307299A1/en not_active Expired
- 1964-12-19 ES ES0307300A patent/ES307300A1/en not_active Expired
- 1964-12-19 NO NO15606364A patent/NO119274B/no unknown
- 1964-12-19 NO NO15606264A patent/NO119273B/no unknown
- 1964-12-19 DK DK626864A patent/DK106552C/en active
- 1964-12-19 DK DK626764A patent/DK108495C/en active
- 1964-12-19 ES ES0307301A patent/ES307301A1/en not_active Expired
- 1964-12-19 ES ES0307302A patent/ES307302A1/en not_active Expired
- 1964-12-19 DK DK429865A patent/DK108497C/en active
- 1964-12-19 DK DK429765A patent/DK108496C/en active
- 1964-12-21 BE BE657406D patent/BE657406A/xx unknown
- 1964-12-21 BE BE657405D patent/BE657405A/xx unknown
-
1965
- 1965-03-19 FR FR9866A patent/FR4346M/fr active Active
- 1965-03-19 FR FR9865A patent/FR4345M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AT249276B (en) | 1966-09-12 |
| IL22643A (en) | 1968-07-25 |
| FR4345M (en) | 1966-08-16 |
| DK108496C (en) | 1967-12-27 |
| ES307299A1 (en) | 1965-05-16 |
| SE305657B (en) | 1968-11-04 |
| NL127995C (en) | |
| DK108497C (en) | 1967-12-27 |
| ES307300A1 (en) | 1965-05-01 |
| NO119274B (en) | 1970-04-27 |
| CH448118A (en) | 1967-12-15 |
| DE1445854A1 (en) | 1968-12-05 |
| CH449639A (en) | 1968-01-15 |
| AT261126B (en) | 1968-04-10 |
| AT249277B (en) | 1966-09-12 |
| DK108495C (en) | 1967-12-27 |
| SE322779B (en) | 1970-04-20 |
| BE657406A (en) | 1965-06-21 |
| DE1445853A1 (en) | 1968-12-05 |
| ES307302A1 (en) | 1965-05-16 |
| NO119273B (en) | 1970-04-27 |
| NL6414821A (en) | 1965-06-21 |
| BE657405A (en) | 1965-06-21 |
| CH446371A (en) | 1967-11-15 |
| IL22642A (en) | 1968-07-25 |
| DK106552C (en) | 1967-02-20 |
| CH449643A (en) | 1968-01-15 |
| NL6414820A (en) | 1965-06-21 |
| GB1077711A (en) | 1967-08-02 |
| FR4346M (en) | 1966-08-16 |
| CH449640A (en) | 1968-01-15 |
| GB1092394A (en) | 1967-11-22 |
| CH449642A (en) | 1968-01-15 |
| ES307301A1 (en) | 1965-05-16 |
| AT253687B (en) | 1967-04-25 |
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