IL22642A - New benzomorphans and process for the production thereof - Google Patents
New benzomorphans and process for the production thereofInfo
- Publication number
- IL22642A IL22642A IL2264264A IL2264264A IL22642A IL 22642 A IL22642 A IL 22642A IL 2264264 A IL2264264 A IL 2264264A IL 2264264 A IL2264264 A IL 2264264A IL 22642 A IL22642 A IL 22642A
- Authority
- IL
- Israel
- Prior art keywords
- benzomorphans
- new
- production
- new benzomorphans
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Discharge Lamp (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33229663A | 1963-12-20 | 1963-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL22642A true IL22642A (en) | 1968-07-25 |
Family
ID=23297612
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL2264264A IL22642A (en) | 1963-12-20 | 1964-12-18 | New benzomorphans and process for the production thereof |
| IL2264364A IL22643A (en) | 1963-12-20 | 1964-12-18 | Benzomorphan derivatives and a process for their production |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL2264364A IL22643A (en) | 1963-12-20 | 1964-12-18 | Benzomorphan derivatives and a process for their production |
Country Status (12)
| Country | Link |
|---|---|
| AT (4) | AT249277B (en) |
| BE (2) | BE657405A (en) |
| CH (7) | CH449642A (en) |
| DE (2) | DE1445853A1 (en) |
| DK (4) | DK108496C (en) |
| ES (4) | ES307299A1 (en) |
| FR (2) | FR4346M (en) |
| GB (2) | GB1077711A (en) |
| IL (2) | IL22642A (en) |
| NL (3) | NL6414821A (en) |
| NO (2) | NO119273B (en) |
| SE (2) | SE322779B (en) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003097608A2 (en) | 2002-05-17 | 2003-11-27 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| CA2678577A1 (en) | 2007-02-26 | 2008-09-04 | Vitae Pharmaceuticals, Inc. | Cyclic urea and carbamate inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
| AR067673A1 (en) | 2007-07-26 | 2009-10-21 | Vitae Pharmaceuticals Inc | DERIVATIVES OF 1,3 OXAZINAN - 2 - ONA AS CYCLE INHIBITORS OF THE 11 BETA -HYDROXIESTEROID DEHYDROGENASE 1. PHARMACEUTICAL COMPOSITIONS. |
| AR069207A1 (en) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | CYCLIC UREAS AS INHIBITORS OF THE 11 BETA - HIDROXI-ESTEROIDE DESHIDROGENASA 1 |
| AR069545A1 (en) | 2007-11-16 | 2010-02-03 | Boehringer Ingelheim Pharma | DERIVATIVES OF ARIL AND HETEROARILCARBONILO OF RELATED BENZOMORPHANS AND RELATED STRUCTURES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, OBTAINING THEMSELVES, THEIR USE IN THE TREATMENT OF DISEASES MEDIATED BY THE INHIBITION OF THE HIDDEN AND DISEASE |
| US8440658B2 (en) | 2007-12-11 | 2013-05-14 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| WO2009094169A1 (en) | 2008-01-24 | 2009-07-30 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| JP5734666B2 (en) | 2008-02-11 | 2015-06-17 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | 1,3-oxaazepan-2-one and 1,3-diazepan-2-one inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| US20110028445A1 (en) * | 2008-02-12 | 2011-02-03 | Boehringer Ingelheim International Gmbh | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| JP5730021B2 (en) | 2008-02-15 | 2015-06-03 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Cycloalkyllactam derivatives as inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| US8569292B2 (en) | 2008-05-01 | 2013-10-29 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| EP2291373B1 (en) | 2008-05-01 | 2013-09-11 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| ES2421537T3 (en) | 2008-05-01 | 2013-09-03 | Vitae Pharmaceuticals Inc | Cyclic 11beta-hydroxysteroid dehydrogenase 1 inhibitors |
| CA2723034A1 (en) | 2008-05-01 | 2009-11-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| AR071719A1 (en) | 2008-05-13 | 2010-07-07 | Boehringer Ingelheim Int | ALICICLIC DERIVATIVES OF CARBOXILIC ACID OF BENZOMORPHANS AND RELATED STRUCTURES, MEDICINES CONTAINING THESE COMPOUNDS AND THEIR USE. OBTAINING PROCESSES |
| PL2324018T3 (en) | 2008-07-25 | 2014-02-28 | Boehringer Ingelheim Int | Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1 |
| US8846668B2 (en) | 2008-07-25 | 2014-09-30 | Vitae Pharmaceuticals, Inc. | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| AR073920A1 (en) | 2008-10-23 | 2010-12-09 | Boehringer Ingelheim Int | UREA DERIVATIVES OF SUBSTITUTED NORTROPANS, DRUGS CONTAINING THESE COMPOUNDS, THEIR USE IN THE TREATMENT OF DISEASES MEDIATED BY THE INHIBITION OF THE 11BETA-HYDROXIESTEROID DISHYDROGENASE DISEASE AND PROCESS FOR PREPARATION. |
| CA2744946A1 (en) | 2009-02-04 | 2010-08-12 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
| US8680093B2 (en) | 2009-04-30 | 2014-03-25 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8703765B2 (en) | 2009-06-02 | 2014-04-22 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| US8927539B2 (en) | 2009-06-11 | 2015-01-06 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure |
| JP5749263B2 (en) | 2009-07-01 | 2015-07-15 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1 |
| UY33001A (en) | 2009-11-06 | 2011-05-31 | Boehringer Ingelheim Int | ARYL AND HETEROARILCARBONYL HIVAHYDROINDENOPIRIDINE AND OCTAHYDROBENZOQUINOLINE DERIVATIVES |
| US8933072B2 (en) | 2010-06-16 | 2015-01-13 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
| JP5813106B2 (en) | 2010-06-25 | 2015-11-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Azaspirohexanone as an inhibitor of 11-β-HSD1 for the treatment of metabolic disorders |
| AU2011325286B2 (en) | 2010-11-02 | 2015-04-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical combinations for the treatment of metabolic disorders |
| TWI537258B (en) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline |
| EP2744783A1 (en) | 2011-08-17 | 2014-06-25 | Boehringer Ingelheim International GmbH | Indenopyridine derivatives |
-
0
- NL NL127995D patent/NL127995C/xx active
-
1964
- 1964-11-30 CH CH1619067A patent/CH449642A/en unknown
- 1964-11-30 CH CH1538364A patent/CH448118A/en unknown
- 1964-11-30 CH CH1619167A patent/CH449643A/en unknown
- 1964-11-30 CH CH1618867A patent/CH449640A/en unknown
- 1964-11-30 CH CH1618767A patent/CH449639A/en unknown
- 1964-11-30 CH CH1618967A patent/CH449641A/en unknown
- 1964-11-30 CH CH1538464A patent/CH446371A/en unknown
- 1964-12-18 DE DE19641445853 patent/DE1445853A1/en active Pending
- 1964-12-18 SE SE1536064A patent/SE322779B/xx unknown
- 1964-12-18 NL NL6414821A patent/NL6414821A/xx unknown
- 1964-12-18 IL IL2264264A patent/IL22642A/en unknown
- 1964-12-18 AT AT392965A patent/AT249277B/en active
- 1964-12-18 AT AT392865A patent/AT249276B/en active
- 1964-12-18 GB GB5149864A patent/GB1077711A/en not_active Expired
- 1964-12-18 AT AT1074364A patent/AT253687B/en active
- 1964-12-18 AT AT1074264A patent/AT261126B/en active
- 1964-12-18 GB GB5150064A patent/GB1092394A/en not_active Expired
- 1964-12-18 DE DE19641445854 patent/DE1445854A1/en active Pending
- 1964-12-18 SE SE1536164A patent/SE305657B/xx unknown
- 1964-12-18 NL NL6414820A patent/NL6414820A/xx unknown
- 1964-12-18 IL IL2264364A patent/IL22643A/en unknown
- 1964-12-19 NO NO15606264A patent/NO119273B/no unknown
- 1964-12-19 DK DK429765A patent/DK108496C/en active
- 1964-12-19 DK DK626764A patent/DK108495C/en active
- 1964-12-19 ES ES0307299A patent/ES307299A1/en not_active Expired
- 1964-12-19 ES ES0307301A patent/ES307301A1/en not_active Expired
- 1964-12-19 ES ES0307302A patent/ES307302A1/en not_active Expired
- 1964-12-19 NO NO15606364A patent/NO119274B/no unknown
- 1964-12-19 DK DK626864A patent/DK106552C/en active
- 1964-12-19 DK DK429865A patent/DK108497C/en active
- 1964-12-19 ES ES0307300A patent/ES307300A1/en not_active Expired
- 1964-12-21 BE BE657405D patent/BE657405A/xx unknown
- 1964-12-21 BE BE657406D patent/BE657406A/xx unknown
-
1965
- 1965-03-19 FR FR9866A patent/FR4346M/fr active Active
- 1965-03-19 FR FR9865A patent/FR4345M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DK108497C (en) | 1967-12-27 |
| AT249276B (en) | 1966-09-12 |
| SE322779B (en) | 1970-04-20 |
| CH449639A (en) | 1968-01-15 |
| IL22643A (en) | 1968-07-25 |
| CH449640A (en) | 1968-01-15 |
| CH449641A (en) | 1968-01-15 |
| NO119274B (en) | 1970-04-27 |
| DE1445854A1 (en) | 1968-12-05 |
| BE657406A (en) | 1965-06-21 |
| AT253687B (en) | 1967-04-25 |
| ES307299A1 (en) | 1965-05-16 |
| NO119273B (en) | 1970-04-27 |
| BE657405A (en) | 1965-06-21 |
| AT261126B (en) | 1968-04-10 |
| NL6414821A (en) | 1965-06-21 |
| AT249277B (en) | 1966-09-12 |
| ES307301A1 (en) | 1965-05-16 |
| DE1445853A1 (en) | 1968-12-05 |
| NL6414820A (en) | 1965-06-21 |
| FR4346M (en) | 1966-08-16 |
| ES307300A1 (en) | 1965-05-01 |
| ES307302A1 (en) | 1965-05-16 |
| GB1092394A (en) | 1967-11-22 |
| DK108495C (en) | 1967-12-27 |
| CH448118A (en) | 1967-12-15 |
| FR4345M (en) | 1966-08-16 |
| CH449642A (en) | 1968-01-15 |
| GB1077711A (en) | 1967-08-02 |
| CH446371A (en) | 1967-11-15 |
| DK108496C (en) | 1967-12-27 |
| SE305657B (en) | 1968-11-04 |
| CH449643A (en) | 1968-01-15 |
| NL127995C (en) | |
| DK106552C (en) | 1967-02-20 |
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