CH449639A - Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen - Google Patents
Verfahren zur Herstellung von neuen substituierten 6,7-BenzomorphanenInfo
- Publication number
- CH449639A CH449639A CH1618767A CH1618767A CH449639A CH 449639 A CH449639 A CH 449639A CH 1618767 A CH1618767 A CH 1618767A CH 1618767 A CH1618767 A CH 1618767A CH 449639 A CH449639 A CH 449639A
- Authority
- CH
- Switzerland
- Prior art keywords
- benzomorphans
- preparation
- new substituted
- substituted
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Discharge Lamp (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33229663A | 1963-12-20 | 1963-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH449639A true CH449639A (de) | 1968-01-15 |
Family
ID=23297612
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1538464A CH446371A (de) | 1963-12-20 | 1964-11-30 | Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen |
| CH1619167A CH449643A (de) | 1963-12-20 | 1964-11-30 | Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen |
| CH1618767A CH449639A (de) | 1963-12-20 | 1964-11-30 | Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen |
| CH1618867A CH449640A (de) | 1963-12-20 | 1964-11-30 | Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen |
| CH1619067A CH449642A (de) | 1963-12-20 | 1964-11-30 | Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen |
| CH1538364A CH448118A (de) | 1963-12-20 | 1964-11-30 | Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen |
| CH1618967A CH449641A (de) | 1963-12-20 | 1964-11-30 | Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1538464A CH446371A (de) | 1963-12-20 | 1964-11-30 | Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen |
| CH1619167A CH449643A (de) | 1963-12-20 | 1964-11-30 | Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1618867A CH449640A (de) | 1963-12-20 | 1964-11-30 | Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen |
| CH1619067A CH449642A (de) | 1963-12-20 | 1964-11-30 | Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen |
| CH1538364A CH448118A (de) | 1963-12-20 | 1964-11-30 | Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen |
| CH1618967A CH449641A (de) | 1963-12-20 | 1964-11-30 | Verfahren zur Herstellung von neuen substituierten 6,7-Benzomorphanen |
Country Status (12)
| Country | Link |
|---|---|
| AT (4) | AT249276B (de) |
| BE (2) | BE657405A (de) |
| CH (7) | CH446371A (de) |
| DE (2) | DE1445853A1 (de) |
| DK (4) | DK108497C (de) |
| ES (4) | ES307299A1 (de) |
| FR (2) | FR4346M (de) |
| GB (2) | GB1077711A (de) |
| IL (2) | IL22642A (de) |
| NL (3) | NL6414821A (de) |
| NO (2) | NO119273B (de) |
| SE (2) | SE305657B (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1506174B1 (de) | 2002-05-17 | 2015-09-30 | Taiwanj Pharmaceuticals Co., Ltd. | Verwendung von naltrexon zur behandlung von nieren- und leberschäden |
| US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| WO2008106128A2 (en) | 2007-02-26 | 2008-09-04 | Vitae Pharmaceuticals, Inc. | CYCLIC UREA AND CARBAMATE INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE 1 |
| ES2395081T3 (es) | 2007-07-26 | 2013-02-08 | Vitae Pharmaceuticals, Inc. | Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1 |
| AR069207A1 (es) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
| EP2220048B1 (de) | 2007-11-16 | 2017-01-25 | Boehringer Ingelheim International GmbH | Aryl- und heteroarylcarbonylderivate von benzomorphanen und verwandten grundgerüsten, solche verbindungen enthaltende medikamente und deren verwendung |
| WO2009075835A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceutical, Inc | CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1 |
| TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| CA2712500A1 (en) | 2008-01-24 | 2009-07-30 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| WO2009102428A2 (en) | 2008-02-11 | 2009-08-20 | Vitae Pharmaceuticals, Inc. | 1,3-OXAZEPAN-2-ONE AND 1,3-DIAZEPAN-2-ONE INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE 1 |
| EP2245014B1 (de) * | 2008-02-12 | 2011-11-02 | Boehringer Ingelheim International GmbH | Harnstoff-derivate von benzomorphanen, entsprechende gerüste, medikamente mit solchen verbindungen und ihre verwendung |
| WO2009102460A2 (en) | 2008-02-15 | 2009-08-20 | Vitae Pharmaceuticals, Inc. | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| JP5451752B2 (ja) | 2008-05-01 | 2014-03-26 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター |
| EP2300461B1 (de) | 2008-05-01 | 2013-04-17 | Vitae Pharmaceuticals, Inc. | Cyclische inhibitoren von 11beta-hydroxysteroiddehydrogenase 1 |
| JP5538365B2 (ja) | 2008-05-01 | 2014-07-02 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤 |
| US8569292B2 (en) | 2008-05-01 | 2013-10-29 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| US8765780B2 (en) | 2008-05-13 | 2014-07-01 | Boehringer Ingelheim International Gmbh | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
| RU2539979C2 (ru) | 2008-07-25 | 2015-01-27 | Вайтаи Фармасьютиклз, Инк. | Циклические ингибиторы 11бета-гидроксистероид-дегидрогеназы 1 |
| JP5777030B2 (ja) | 2008-07-25 | 2015-09-09 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤 |
| JP5544366B2 (ja) | 2008-10-23 | 2014-07-09 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換ノルトロパンの尿素誘導体、該化合物を含有する医薬及びその使用 |
| WO2010089303A1 (en) | 2009-02-04 | 2010-08-12 | Boehringer Ingelheim International Gmbh | CYCLIC INHIBITORS OF 11 β-HYDROXYSTEROID DEHYDROGENASE 1 |
| UA109255C2 (ru) | 2009-04-30 | 2015-08-10 | Берінгер Інгельхайм Інтернешнл Гмбх | Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1 |
| US8703765B2 (en) | 2009-06-02 | 2014-04-22 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| EP2440537A1 (de) | 2009-06-11 | 2012-04-18 | Vitae Pharmaceuticals, Inc. | Cyclische hemmer der 11beta-hydroxysteroiddehydrogenase 1 auf basis der 1,3 -oxazinan- 2 -on-struktur |
| WO2011002910A1 (en) | 2009-07-01 | 2011-01-06 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| TWI531571B (zh) | 2009-11-06 | 2016-05-01 | 維它藥物公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物 |
| WO2011159760A1 (en) | 2010-06-16 | 2011-12-22 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
| JP5813106B2 (ja) | 2010-06-25 | 2015-11-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 代謝障害の処置のための１１−β−ＨＳＤ１のインヒビターとしてのアザスピロヘキサノン |
| EP2635268A1 (de) | 2010-11-02 | 2013-09-11 | Boehringer Ingelheim International GmbH | Pharmazeutische kombinationen zur behandlung von stoffwechselerkrankungen |
| TWI537258B (zh) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物 |
| EP2744783A1 (de) | 2011-08-17 | 2014-06-25 | Boehringer Ingelheim International GmbH | Indenopyridinderivate |
-
0
- NL NL127995D patent/NL127995C/xx active
-
1964
- 1964-11-30 CH CH1538464A patent/CH446371A/de unknown
- 1964-11-30 CH CH1619167A patent/CH449643A/de unknown
- 1964-11-30 CH CH1618767A patent/CH449639A/de unknown
- 1964-11-30 CH CH1618867A patent/CH449640A/de unknown
- 1964-11-30 CH CH1619067A patent/CH449642A/de unknown
- 1964-11-30 CH CH1538364A patent/CH448118A/de unknown
- 1964-11-30 CH CH1618967A patent/CH449641A/de unknown
- 1964-12-18 IL IL2264264A patent/IL22642A/xx unknown
- 1964-12-18 AT AT392865A patent/AT249276B/de active
- 1964-12-18 IL IL2264364A patent/IL22643A/xx unknown
- 1964-12-18 NL NL6414821A patent/NL6414821A/xx unknown
- 1964-12-18 GB GB5149864A patent/GB1077711A/en not_active Expired
- 1964-12-18 SE SE1536164A patent/SE305657B/xx unknown
- 1964-12-18 NL NL6414820A patent/NL6414820A/xx unknown
- 1964-12-18 SE SE1536064A patent/SE322779B/xx unknown
- 1964-12-18 GB GB5150064A patent/GB1092394A/en not_active Expired
- 1964-12-18 AT AT392965A patent/AT249277B/de active
- 1964-12-18 DE DE19641445853 patent/DE1445853A1/de active Pending
- 1964-12-18 DE DE19641445854 patent/DE1445854A1/de active Pending
- 1964-12-18 AT AT1074264A patent/AT261126B/de active
- 1964-12-18 AT AT1074364A patent/AT253687B/de active
- 1964-12-19 ES ES0307299A patent/ES307299A1/es not_active Expired
- 1964-12-19 DK DK429865A patent/DK108497C/da active
- 1964-12-19 ES ES0307302A patent/ES307302A1/es not_active Expired
- 1964-12-19 NO NO15606264A patent/NO119273B/no unknown
- 1964-12-19 ES ES0307300A patent/ES307300A1/es not_active Expired
- 1964-12-19 DK DK626764A patent/DK108495C/da active
- 1964-12-19 NO NO15606364A patent/NO119274B/no unknown
- 1964-12-19 ES ES0307301A patent/ES307301A1/es not_active Expired
- 1964-12-19 DK DK626864A patent/DK106552C/da active
- 1964-12-19 DK DK429765A patent/DK108496C/da active
- 1964-12-21 BE BE657405D patent/BE657405A/xx unknown
- 1964-12-21 BE BE657406D patent/BE657406A/xx unknown
-
1965
- 1965-03-19 FR FR9866A patent/FR4346M/fr active Active
- 1965-03-19 FR FR9865A patent/FR4345M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CH449642A (de) | 1968-01-15 |
| CH449640A (de) | 1968-01-15 |
| DK106552C (da) | 1967-02-20 |
| CH449643A (de) | 1968-01-15 |
| ES307301A1 (es) | 1965-05-16 |
| AT249277B (de) | 1966-09-12 |
| FR4346M (de) | 1966-08-16 |
| NO119273B (de) | 1970-04-27 |
| ES307300A1 (es) | 1965-05-01 |
| ES307302A1 (es) | 1965-05-16 |
| DK108496C (da) | 1967-12-27 |
| CH449641A (de) | 1968-01-15 |
| BE657405A (de) | 1965-06-21 |
| AT261126B (de) | 1968-04-10 |
| NL6414821A (de) | 1965-06-21 |
| NL6414820A (de) | 1965-06-21 |
| IL22642A (en) | 1968-07-25 |
| SE305657B (de) | 1968-11-04 |
| NL127995C (de) | |
| GB1077711A (en) | 1967-08-02 |
| NO119274B (de) | 1970-04-27 |
| AT249276B (de) | 1966-09-12 |
| IL22643A (en) | 1968-07-25 |
| CH448118A (de) | 1967-12-15 |
| GB1092394A (en) | 1967-11-22 |
| SE322779B (de) | 1970-04-20 |
| AT253687B (de) | 1967-04-25 |
| DE1445854A1 (de) | 1968-12-05 |
| BE657406A (de) | 1965-06-21 |
| ES307299A1 (es) | 1965-05-16 |
| DK108497C (da) | 1967-12-27 |
| DK108495C (da) | 1967-12-27 |
| FR4345M (de) | 1966-08-16 |
| CH446371A (de) | 1967-11-15 |
| DE1445853A1 (de) | 1968-12-05 |
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