AT261126B - Verfahren zur Herstellung von neuen Benzomorphanen - Google Patents
Verfahren zur Herstellung von neuen BenzomorphanenInfo
- Publication number
- AT261126B AT261126B AT1074264A AT1074264A AT261126B AT 261126 B AT261126 B AT 261126B AT 1074264 A AT1074264 A AT 1074264A AT 1074264 A AT1074264 A AT 1074264A AT 261126 B AT261126 B AT 261126B
- Authority
- AT
- Austria
- Prior art keywords
- benzomorphans
- new
- production
- new benzomorphans
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Discharge Lamp (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33229663A | 1963-12-20 | 1963-12-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
AT261126B true AT261126B (de) | 1968-04-10 |
Family
ID=23297612
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT392865A AT249276B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung neuer Benzomorphane |
AT392965A AT249277B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung neuer Benzomorphane |
AT1074264A AT261126B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung von neuen Benzomorphanen |
AT1074364A AT253687B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung von neuen Benzomorphanen |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT392865A AT249276B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung neuer Benzomorphane |
AT392965A AT249277B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung neuer Benzomorphane |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT1074364A AT253687B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung von neuen Benzomorphanen |
Country Status (12)
Country | Link |
---|---|
AT (4) | AT249276B (de) |
BE (2) | BE657406A (de) |
CH (7) | CH449639A (de) |
DE (2) | DE1445854A1 (de) |
DK (4) | DK108497C (de) |
ES (4) | ES307299A1 (de) |
FR (2) | FR4346M (de) |
GB (2) | GB1077711A (de) |
IL (2) | IL22643A (de) |
NL (3) | NL6414821A (de) |
NO (2) | NO119274B (de) |
SE (2) | SE305657B (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
EP2987788A1 (de) | 2002-05-17 | 2016-02-24 | Taiwanj Pharmaceuticals Co., Ltd. | Opioid und opioidähnliche verbindungen und verwendung davon |
US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
EP2125750B1 (de) | 2007-02-26 | 2014-05-21 | Vitae Pharmaceuticals, Inc. | Zyklische harnstoff- und carbamat-hemmer aus 11-beta-hydroxysteroid-dehydrogenase 1 |
ATE554078T1 (de) | 2007-07-26 | 2012-05-15 | Vitae Pharmaceuticals Inc | Synthese von 11-beta-hydroxysteroid-dehydrogenase-1-hemmern |
AR069207A1 (es) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
CL2008003407A1 (es) | 2007-11-16 | 2010-01-11 | Boehringer Ingelheim Int | Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1. |
WO2009075835A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceutical, Inc | CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1 |
TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
US8592409B2 (en) | 2008-01-24 | 2013-11-26 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
JP5734666B2 (ja) | 2008-02-11 | 2015-06-17 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の1,3−オキサアゼパン−2−オン及び1,3−ジアゼパン−2−オン阻害剤 |
EP2245014B1 (de) * | 2008-02-12 | 2011-11-02 | Boehringer Ingelheim International GmbH | Harnstoff-derivate von benzomorphanen, entsprechende gerüste, medikamente mit solchen verbindungen und ihre verwendung |
JP5730021B2 (ja) | 2008-02-15 | 2015-06-03 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤としてのシクロアルキルラクタム誘導体 |
AR071609A1 (es) | 2008-05-01 | 2010-06-30 | Vitae Pharmaceuticals Inc | Inhibidores ciclicos de 11(beta) -hidroxiesteroide deshidrogenasa 1 |
EP2291370B1 (de) | 2008-05-01 | 2013-11-27 | Vitae Pharmaceuticals, Inc. | Cyclische inhibitoren von 11beta-hydroxysteroiddehydrogenase 1 |
CA2723032A1 (en) | 2008-05-01 | 2009-11-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
AR071236A1 (es) | 2008-05-01 | 2010-06-02 | Vitae Pharmaceuticals Inc | Inhibidores ciclicos de la 11beta-hidroxiesteroide deshidrogenasa 1 |
CL2009001151A1 (es) | 2008-05-13 | 2010-08-13 | Boehringer Ingelheim Int | Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos. |
CA2730499A1 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
WO2010010157A2 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1 |
TW201022266A (en) | 2008-10-23 | 2010-06-16 | Boehringer Ingelheim Int | Urea derivatives of substituted nortropanes, medicaments containing such compounds and their use |
EP2393807B1 (de) | 2009-02-04 | 2013-08-14 | Boehringer Ingelheim International GmbH | Zyklische 11beta-hydroxysteroid-dehydrogenase-1-hemmer |
MA33216B1 (fr) | 2009-04-30 | 2012-04-02 | Boehringer Ingelheim Int | Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1 |
EP2438049B1 (de) | 2009-06-02 | 2014-05-14 | Boehringer Ingelheim International GmbH | Cyclische inhibitoren von 11beta-hydroxysteroiddehydrogenase 1 |
EP2440537A1 (de) | 2009-06-11 | 2012-04-18 | Vitae Pharmaceuticals, Inc. | Cyclische hemmer der 11beta-hydroxysteroiddehydrogenase 1 auf basis der 1,3 -oxazinan- 2 -on-struktur |
US8883778B2 (en) | 2009-07-01 | 2014-11-11 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1 |
TWI531571B (zh) | 2009-11-06 | 2016-05-01 | 維它藥物公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜芳基羰基衍生物 |
EP2582698B1 (de) | 2010-06-16 | 2016-09-14 | Vitae Pharmaceuticals, Inc. | Substituierte 5-,6- und 7-gliedrige heterocyclen, medikamente mit derartigen verbindungen und ihre verwendung |
EP2585444B1 (de) | 2010-06-25 | 2014-10-22 | Boehringer Ingelheim International GmbH | Azaspirohexanone als 11-beta-hsd1-hemmer zur behandlung von stoffwechselerkrankungen |
WO2012059416A1 (en) | 2010-11-02 | 2012-05-10 | Boehringer Ingelheim International Gmbh | Pharmaceutical combinations for the treatment of metabolic disorders |
TWI537258B (zh) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物 |
WO2013025664A1 (en) | 2011-08-17 | 2013-02-21 | Boehringer Ingelheim International Gmbh | Indenopyridine derivatives |
-
0
- NL NL127995D patent/NL127995C/xx active
-
1964
- 1964-11-30 CH CH1618767A patent/CH449639A/de unknown
- 1964-11-30 CH CH1619167A patent/CH449643A/de unknown
- 1964-11-30 CH CH1618867A patent/CH449640A/de unknown
- 1964-11-30 CH CH1619067A patent/CH449642A/de unknown
- 1964-11-30 CH CH1538464A patent/CH446371A/de unknown
- 1964-11-30 CH CH1618967A patent/CH449641A/de unknown
- 1964-11-30 CH CH1538364A patent/CH448118A/de unknown
- 1964-12-18 DE DE19641445854 patent/DE1445854A1/de active Pending
- 1964-12-18 DE DE19641445853 patent/DE1445853A1/de active Pending
- 1964-12-18 IL IL2264364A patent/IL22643A/xx unknown
- 1964-12-18 NL NL6414821A patent/NL6414821A/xx unknown
- 1964-12-18 SE SE1536164A patent/SE305657B/xx unknown
- 1964-12-18 GB GB5149864A patent/GB1077711A/en not_active Expired
- 1964-12-18 AT AT392865A patent/AT249276B/de active
- 1964-12-18 IL IL2264264A patent/IL22642A/xx unknown
- 1964-12-18 GB GB5150064A patent/GB1092394A/en not_active Expired
- 1964-12-18 SE SE1536064A patent/SE322779B/xx unknown
- 1964-12-18 AT AT392965A patent/AT249277B/de active
- 1964-12-18 AT AT1074264A patent/AT261126B/de active
- 1964-12-18 AT AT1074364A patent/AT253687B/de active
- 1964-12-18 NL NL6414820A patent/NL6414820A/xx unknown
- 1964-12-19 DK DK429865A patent/DK108497C/da active
- 1964-12-19 NO NO15606364A patent/NO119274B/no unknown
- 1964-12-19 ES ES0307299A patent/ES307299A1/es not_active Expired
- 1964-12-19 ES ES0307300A patent/ES307300A1/es not_active Expired
- 1964-12-19 NO NO15606264A patent/NO119273B/no unknown
- 1964-12-19 DK DK626864A patent/DK106552C/da active
- 1964-12-19 ES ES0307301A patent/ES307301A1/es not_active Expired
- 1964-12-19 DK DK429765A patent/DK108496C/da active
- 1964-12-19 DK DK626764A patent/DK108495C/da active
- 1964-12-19 ES ES0307302A patent/ES307302A1/es not_active Expired
- 1964-12-21 BE BE657406D patent/BE657406A/xx unknown
- 1964-12-21 BE BE657405D patent/BE657405A/xx unknown
-
1965
- 1965-03-19 FR FR9866A patent/FR4346M/fr active Active
- 1965-03-19 FR FR9865A patent/FR4345M/fr active Active
Also Published As
Publication number | Publication date |
---|---|
NO119273B (de) | 1970-04-27 |
NL6414821A (de) | 1965-06-21 |
SE305657B (de) | 1968-11-04 |
IL22642A (en) | 1968-07-25 |
GB1092394A (en) | 1967-11-22 |
CH449641A (de) | 1968-01-15 |
ES307301A1 (es) | 1965-05-16 |
DK108497C (da) | 1967-12-27 |
DK106552C (da) | 1967-02-20 |
NL6414820A (de) | 1965-06-21 |
CH449643A (de) | 1968-01-15 |
ES307300A1 (es) | 1965-05-01 |
DE1445853A1 (de) | 1968-12-05 |
DK108495C (da) | 1967-12-27 |
CH449639A (de) | 1968-01-15 |
ES307302A1 (es) | 1965-05-16 |
NO119274B (de) | 1970-04-27 |
AT253687B (de) | 1967-04-25 |
AT249277B (de) | 1966-09-12 |
CH449640A (de) | 1968-01-15 |
ES307299A1 (es) | 1965-05-16 |
BE657406A (de) | 1965-06-21 |
SE322779B (de) | 1970-04-20 |
NL127995C (de) | |
DK108496C (da) | 1967-12-27 |
CH449642A (de) | 1968-01-15 |
AT249276B (de) | 1966-09-12 |
CH446371A (de) | 1967-11-15 |
IL22643A (en) | 1968-07-25 |
FR4345M (de) | 1966-08-16 |
CH448118A (de) | 1967-12-15 |
FR4346M (de) | 1966-08-16 |
GB1077711A (en) | 1967-08-02 |
DE1445854A1 (de) | 1968-12-05 |
BE657405A (de) | 1965-06-21 |
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