DK1077692T3 - Aminosyrestabiliserede gabapentin- og pregabalinpræparater og fremgangsmåder til fremstilling deraf - Google Patents

Aminosyrestabiliserede gabapentin- og pregabalinpræparater og fremgangsmåder til fremstilling deraf

Info

Publication number
DK1077692T3
DK1077692T3 DK99924166T DK99924166T DK1077692T3 DK 1077692 T3 DK1077692 T3 DK 1077692T3 DK 99924166 T DK99924166 T DK 99924166T DK 99924166 T DK99924166 T DK 99924166T DK 1077692 T3 DK1077692 T3 DK 1077692T3
Authority
DK
Denmark
Prior art keywords
pregabalin
gabapentin
preparations
preparation
methods
Prior art date
Application number
DK99924166T
Other languages
Danish (da)
English (en)
Inventor
Akira Aomatsu
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15097118&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1077692(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of DK1077692T3 publication Critical patent/DK1077692T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymerisation Methods In General (AREA)
DK99924166T 1998-05-15 1999-05-10 Aminosyrestabiliserede gabapentin- og pregabalinpræparater og fremgangsmåder til fremstilling deraf DK1077692T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13311398 1998-05-15
EP99924166A EP1077692B1 (en) 1998-05-15 1999-05-10 Amino acid stabilized gabapentin and pregabalin preparations and process for preparing the same

Publications (1)

Publication Number Publication Date
DK1077692T3 true DK1077692T3 (da) 2004-12-06

Family

ID=15097118

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99924166T DK1077692T3 (da) 1998-05-15 1999-05-10 Aminosyrestabiliserede gabapentin- og pregabalinpræparater og fremgangsmåder til fremstilling deraf

Country Status (37)

Country Link
US (1) US7309719B1 (id)
EP (1) EP1077692B1 (id)
JP (1) JP4612923B2 (id)
KR (1) KR100602047B1 (id)
CN (1) CN1303991C (id)
AR (1) AR020323A1 (id)
AT (1) ATE271864T1 (id)
AU (1) AU768277B2 (id)
BR (1) BR9910508B1 (id)
CA (1) CA2327285C (id)
CO (1) CO5021224A1 (id)
CR (1) CR6026A (id)
CU (1) CU23253B7 (id)
DE (1) DE69918977T2 (id)
DK (1) DK1077692T3 (id)
EG (1) EG26803A (id)
ES (1) ES2221385T3 (id)
GT (1) GT199900069A (id)
HK (1) HK1036586A1 (id)
HN (1) HN1999000072A (id)
HU (1) HU228771B1 (id)
ID (1) ID27724A (id)
IL (2) IL139298A0 (id)
IS (1) IS2233B (id)
MY (1) MY157878A (id)
NO (1) NO328959B1 (id)
NZ (1) NZ508015A (id)
PA (1) PA8472801A1 (id)
PE (1) PE20000556A1 (id)
PL (1) PL204921B1 (id)
PT (1) PT1077692E (id)
SI (1) SI1077692T1 (id)
SV (1) SV1999000064A (id)
TW (1) TWI243054B (id)
UY (1) UY25512A1 (id)
WO (1) WO1999059573A1 (id)
ZA (1) ZA200006484B (id)

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CN103494796B (zh) * 2013-09-30 2016-01-20 浙江华义医药有限公司 普瑞巴林稳定的药物组合物及其制备方法
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JP2018520112A (ja) 2015-05-26 2018-07-26 オディディ，イサ 制御持続放出プレガバリン
JP6919119B2 (ja) * 2017-01-23 2021-08-18 日新製薬株式会社 ３位が置換されたγ−アミノ酪酸誘導体を含有する圧縮固形医薬組成物。
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Also Published As

Publication number Publication date
IS5666A (is) 2000-10-16
HUP0102022A3 (en) 2002-11-28
TWI243054B (en) 2005-11-11
AU4073599A (en) 1999-12-06
BR9910508A (pt) 2001-01-02
CU23253B7 (es) 2007-12-17
ID27724A (id) 2001-04-26
EP1077692B1 (en) 2004-07-28
HUP0102022A2 (hu) 2001-11-28
SI1077692T1 (en) 2004-10-31
HK1036586A1 (en) 2002-01-11
NO20005768D0 (no) 2000-11-14
JP2000034226A (ja) 2000-02-02
KR20010043611A (ko) 2001-05-25
JP4612923B2 (ja) 2011-01-12
SV1999000064A (es) 2000-03-31
HN1999000072A (es) 2000-06-05
CR6026A (es) 2008-08-26
NO20005768L (no) 2000-11-14
UY25512A1 (es) 1999-07-19
ZA200006484B (en) 2002-02-11
DE69918977D1 (de) 2004-09-02
DE69918977T2 (de) 2005-07-28
US7309719B1 (en) 2007-12-18
CA2327285C (en) 2005-06-14
PE20000556A1 (es) 2000-08-10
WO1999059573A1 (en) 1999-11-25
AU768277B2 (en) 2003-12-04
CN1303991C (zh) 2007-03-14
ATE271864T1 (de) 2004-08-15
WO1999059573A9 (en) 2000-05-04
NO328959B1 (no) 2010-06-28
PL204921B1 (pl) 2010-02-26
CN1301155A (zh) 2001-06-27
IL139298A0 (en) 2001-11-25
MY157878A (en) 2016-07-29
HU228771B1 (en) 2013-05-28
EP1077692A1 (en) 2001-02-28
EG26803A (en) 2014-09-21
NZ508015A (en) 2003-11-28
PA8472801A1 (es) 2001-12-14
PT1077692E (pt) 2004-12-31
KR100602047B1 (ko) 2006-07-19
PL344218A1 (en) 2001-10-08
IL139298A (en) 2009-07-20
IS2233B (is) 2007-04-15
GT199900069A (es) 2000-11-04
BR9910508B1 (pt) 2012-01-24
CA2327285A1 (en) 1999-11-25
CO5021224A1 (es) 2001-03-27
ES2221385T3 (es) 2004-12-16
AR020323A1 (es) 2002-05-08

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