DK1073647T3 - 12,13-cyclopropan epothilon-derivater - Google Patents

12,13-cyclopropan epothilon-derivater

Info

Publication number
DK1073647T3
DK1073647T3 DK99915273T DK99915273T DK1073647T3 DK 1073647 T3 DK1073647 T3 DK 1073647T3 DK 99915273 T DK99915273 T DK 99915273T DK 99915273 T DK99915273 T DK 99915273T DK 1073647 T3 DK1073647 T3 DK 1073647T3
Authority
DK
Denmark
Prior art keywords
epothilone derivatives
cyclopropane
cyclopropane epothilone
derivatives
epothilone
Prior art date
Application number
DK99915273T
Other languages
Danish (da)
English (en)
Inventor
Gregory D Vite
Gerhard Hofle
Soong-Hoon Kim Kim
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DK1073647T3 publication Critical patent/DK1073647T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK99915273T 1998-04-21 1999-04-05 12,13-cyclopropan epothilon-derivater DK1073647T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8256498P 1998-04-21 1998-04-21
PCT/US1999/007448 WO1999054318A1 (en) 1998-04-21 1999-04-05 12,13-cyclopropane epothilone derivatives

Publications (1)

Publication Number Publication Date
DK1073647T3 true DK1073647T3 (da) 2009-11-09

Family

ID=22171978

Family Applications (3)

Application Number Title Priority Date Filing Date
DK99916383T DK1073648T3 (da) 1998-04-21 1999-04-05 12,13-Modificerede epothilonderivater
DK99915273T DK1073647T3 (da) 1998-04-21 1999-04-05 12,13-cyclopropan epothilon-derivater
DK05015236.2T DK1589017T3 (da) 1998-04-21 1999-04-05 12,13-modificerede epothilon-derivater

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK99916383T DK1073648T3 (da) 1998-04-21 1999-04-05 12,13-Modificerede epothilonderivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK05015236.2T DK1589017T3 (da) 1998-04-21 1999-04-05 12,13-modificerede epothilon-derivater

Country Status (17)

Country Link
US (2) US6399638B1 (tr)
EP (3) EP1073647B1 (tr)
JP (2) JP2002512238A (tr)
CN (1) CN1142923C (tr)
AR (2) AR015774A1 (tr)
AT (2) ATE435861T1 (tr)
AU (2) AU757733B2 (tr)
BR (1) BR9909795A (tr)
CA (2) CA2323609A1 (tr)
CY (2) CY1105836T1 (tr)
DE (2) DE69941083D1 (tr)
DK (3) DK1073648T3 (tr)
ES (3) ES2400049T3 (tr)
PE (1) PE20000460A1 (tr)
PT (3) PT1073648E (tr)
TR (1) TR200003036T2 (tr)
WO (2) WO1999054319A1 (tr)

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Also Published As

Publication number Publication date
JP2002512239A (ja) 2002-04-23
PT1073648E (pt) 2006-12-29
CY1105836T1 (el) 2011-02-02
CA2323609A1 (en) 1999-10-28
EP1073647A4 (en) 2003-01-02
CN1298398A (zh) 2001-06-06
ES2273484T3 (es) 2007-05-01
ES2327803T3 (es) 2009-11-03
AU748526B2 (en) 2002-06-06
EP1589017A2 (en) 2005-10-26
DK1589017T3 (da) 2013-03-18
CY1109593T1 (el) 2014-08-13
AR015007A1 (es) 2001-04-11
AU757733B2 (en) 2003-03-06
DE69941083D1 (en) 2009-08-20
US6399638B1 (en) 2002-06-04
DE69933287T2 (de) 2007-05-03
WO1999054319A1 (en) 1999-10-28
ATE340177T1 (de) 2006-10-15
US6380395B1 (en) 2002-04-30
AU3471699A (en) 1999-11-08
EP1589017A3 (en) 2009-04-22
PE20000460A1 (es) 2000-06-09
AU3382799A (en) 1999-11-08
WO1999054318A1 (en) 1999-10-28
EP1073648A4 (en) 2003-01-02
ATE435861T1 (de) 2009-07-15
EP1073647A1 (en) 2001-02-07
EP1073648A1 (en) 2001-02-07
CA2329181C (en) 2011-02-22
EP1073648B1 (en) 2006-09-20
EP1073647B1 (en) 2009-07-08
BR9909795A (pt) 2000-12-26
PT1073647E (pt) 2009-07-17
EP1589017B1 (en) 2012-12-05
CN1142923C (zh) 2004-03-24
AR015774A1 (es) 2001-05-16
JP2002512238A (ja) 2002-04-23
CA2329181A1 (en) 1999-10-28
DE69933287D1 (de) 2006-11-02
DK1073648T3 (da) 2007-01-08
PT1589017E (pt) 2013-03-04
ES2400049T3 (es) 2013-04-05
TR200003036T2 (tr) 2001-01-22
JP4476483B2 (ja) 2010-06-09

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