DK1071804T3 - Anvendelse af triplex-struktur-dna-sekvenser til overførsel af nukleotidsekvenser - Google Patents
Anvendelse af triplex-struktur-dna-sekvenser til overførsel af nukleotidsekvenserInfo
- Publication number
- DK1071804T3 DK1071804T3 DK99915829.8T DK99915829T DK1071804T3 DK 1071804 T3 DK1071804 T3 DK 1071804T3 DK 99915829 T DK99915829 T DK 99915829T DK 1071804 T3 DK1071804 T3 DK 1071804T3
- Authority
- DK
- Denmark
- Prior art keywords
- retroviral
- recombinant
- regulators
- particles
- sequence
- Prior art date
Links
- 108091028043 Nucleic acid sequence Proteins 0.000 title 2
- 230000001177 retroviral effect Effects 0.000 abstract 6
- 239000002245 particle Substances 0.000 abstract 3
- 239000002157 polynucleotide Substances 0.000 abstract 3
- 102000040430 polynucleotide Human genes 0.000 abstract 3
- 108091033319 polynucleotide Proteins 0.000 abstract 3
- 238000010839 reverse transcription Methods 0.000 abstract 3
- 108700019146 Transgenes Proteins 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 101710091045 Envelope protein Proteins 0.000 abstract 1
- 101710177291 Gag polyprotein Proteins 0.000 abstract 1
- 101710125418 Major capsid protein Proteins 0.000 abstract 1
- 101710188315 Protein X Proteins 0.000 abstract 1
- 102100021696 Syncytin-1 Human genes 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 239000000824 cytostatic agent Substances 0.000 abstract 1
- 230000001085 cytostatic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 229960001438 immunostimulant agent Drugs 0.000 abstract 1
- 239000003022 immunostimulating agent Substances 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 230000000977 initiatory effect Effects 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
- 108010089520 pol Gene Products Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16061—Methods of inactivation or attenuation
- C12N2740/16062—Methods of inactivation or attenuation by genetic engineering
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9805197A FR2777909B1 (fr) | 1998-04-24 | 1998-04-24 | Utilisation de sequences d'adn de structure triplex pour le tranfert de sequences de nucleotides dans des cellules, vecteurs recombinants contenant ces sequences triplex |
| PCT/FR1999/000974 WO1999055892A1 (fr) | 1998-04-24 | 1999-04-23 | Utilisation de sequences d'adn de structure triplex pour le transfert de sequences nucleotidiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1071804T3 true DK1071804T3 (da) | 2012-07-02 |
Family
ID=9525665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99915829.8T DK1071804T3 (da) | 1998-04-24 | 1999-04-23 | Anvendelse af triplex-struktur-dna-sekvenser til overførsel af nukleotidsekvenser |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US6682907B1 (da) |
| EP (2) | EP2292778B1 (da) |
| JP (1) | JP4571306B2 (da) |
| AT (1) | ATE553205T1 (da) |
| AU (1) | AU3427299A (da) |
| CA (1) | CA2326719C (da) |
| CY (1) | CY1112985T1 (da) |
| DK (1) | DK1071804T3 (da) |
| ES (2) | ES2384553T3 (da) |
| FR (1) | FR2777909B1 (da) |
| HK (1) | HK1034283A1 (da) |
| PT (1) | PT1071804E (da) |
| WO (1) | WO1999055892A1 (da) |
Families Citing this family (118)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2777909B1 (fr) | 1998-04-24 | 2002-08-02 | Pasteur Institut | Utilisation de sequences d'adn de structure triplex pour le tranfert de sequences de nucleotides dans des cellules, vecteurs recombinants contenant ces sequences triplex |
| EP1092779B1 (en) * | 1999-10-11 | 2009-11-25 | Institut Pasteur | Lentiviral vectors for the preparation of immunotherapeutical compositions |
| DK1224314T3 (da) * | 1999-10-12 | 2007-05-21 | Inst Nat Sante Rech Med | Lentiviralt triplex-DNA samt vektorer og rekombinante celler indeholder lentiviralt triplex-DNA |
| US7419829B2 (en) * | 2000-10-06 | 2008-09-02 | Oxford Biomedica (Uk) Limited | Vector system |
| US7575924B2 (en) | 2000-11-13 | 2009-08-18 | Research Development Foundation | Methods and compositions relating to improved lentiviral vectors and their applications |
| DK1412493T3 (da) | 2001-08-02 | 2012-01-09 | Inst Clayton De La Rech | Fremgangsmåder og sammensætninger der angår forbedrede lentiviral-vektor.-produktionsystemer |
| WO2003029412A2 (en) | 2001-10-02 | 2003-04-10 | Institut Clayton De La Recherche | Restricted expression lentivial vectors |
| US20030194392A1 (en) * | 2002-04-10 | 2003-10-16 | Pierre Charneau | Lentiviral triplex DNA, and vectors and recombinant cells containing lentiviral triplex DNA |
| EP1552025A4 (en) * | 2002-10-18 | 2006-12-13 | Cylene Pharmaceuticals Inc | METHODS FOR IDENTIFYING TARGETED ANTIVIRAL MOLECULES TO QUADRUPLEX STRUCTURES |
| FR2870126B1 (fr) * | 2004-05-17 | 2009-07-17 | Pasteur Institut | Vecteur lentiviral recombinant d'expression d'une proteine de flaviviridae et ses applications comme vaccin |
| US8222029B2 (en) | 2005-05-16 | 2012-07-17 | Institut Pasteur | Lentiviral vector-based vaccine |
| EP1748067A1 (en) | 2005-07-29 | 2007-01-31 | Institut Pasteur | Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes |
| EP2150618B1 (en) | 2007-05-04 | 2017-10-11 | University Health Network | Il-12 immunotherapy for cancer |
| WO2009120947A1 (en) * | 2008-03-28 | 2009-10-01 | Virxsys Corporation | Lentivirus-based immunogenic vectors |
| US8323891B2 (en) * | 2008-08-01 | 2012-12-04 | Claflin University | miRNA triplex formations for the downregulation of viral replication |
| EP2385107B1 (en) | 2010-05-03 | 2016-08-24 | Institut Pasteur | Lentiviral vector based immunological compounds against malaria |
| EP2666477A1 (en) | 2012-05-23 | 2013-11-27 | Theravectys | Lentiviral vectors containing an MHC class I promoter |
| EP2643343A1 (en) | 2010-11-26 | 2013-10-02 | Institut Pasteur | Identification of a human gyrovirus and applications. |
| CN103476928B (zh) | 2010-12-09 | 2017-03-29 | 巴斯德研究所 | 用于获得高产量重组蛋白表达的基于mgmt的方法 |
| RS57397B8 (sr) | 2011-06-10 | 2020-01-31 | Univ Oregon Health & Science | Cmv glikoproteini i rekombinantni vektori |
| AU2012267512B2 (en) | 2011-06-10 | 2014-11-20 | Bluebird Bio, Inc. | Gene therapy vectors for adrenoleukodystrophy and adrenomyeloneuropathy |
| EP2568289A3 (en) | 2011-09-12 | 2013-04-03 | International AIDS Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies |
| WO2013043196A1 (en) | 2011-09-23 | 2013-03-28 | Bluebird Bio, Inc. | Improved gene therapy methods |
| EA032699B1 (ru) | 2011-09-30 | 2019-07-31 | Блубёрд Био, Инк. | Способ повышения эффективности трансдукции кроветворных клеток лентивирусом |
| US9402894B2 (en) | 2011-10-27 | 2016-08-02 | International Aids Vaccine Initiative | Viral particles derived from an enveloped virus |
| EP2788477A2 (en) | 2011-12-07 | 2014-10-15 | Institut Pasteur | Identification of a swine parecho-like virus and applications |
| NO2788478T3 (da) | 2011-12-09 | 2018-01-20 | ||
| US9347065B2 (en) | 2012-03-29 | 2016-05-24 | International Aids Vaccine Initiative | Methods to improve vector expression and genetic stability |
| US20150182617A1 (en) | 2012-07-25 | 2015-07-02 | Theravectys | Glycoproteins for pseudotyping lentivectors |
| CN104955943B (zh) | 2012-11-27 | 2018-09-25 | 儿童医疗中心有限公司 | 用于胎儿血红蛋白再诱导的靶向bcl11a远端调控元件 |
| AU2013204922B2 (en) | 2012-12-20 | 2015-05-14 | Celgene Corporation | Chimeric antigen receptors |
| JP6493692B2 (ja) | 2013-03-15 | 2019-04-10 | セルジーン コーポレイション | 修飾されたｔリンパ球 |
| EP2878667A1 (en) | 2013-11-29 | 2015-06-03 | Institut Pasteur | TAL effector means useful for partial or full deletion of DNA tandem repeats |
| KR102161927B1 (ko) | 2014-04-25 | 2020-10-06 | 블루버드 바이오, 인코포레이티드. | 양자 세포 치료제를 제조하는 개선된 방법 |
| WO2015164750A2 (en) | 2014-04-25 | 2015-10-29 | Children's Medical Center Corporation | Compositions and methods to treating hemoglobinopathies |
| CN106536549B (zh) | 2014-04-25 | 2020-01-17 | 蓝鸟生物公司 | Mnd启动子嵌合抗原受体 |
| JP6663359B2 (ja) | 2014-06-06 | 2020-03-11 | ブルーバード バイオ， インコーポレイテッド | 改善されたｔ細胞組成物 |
| RU2747457C2 (ru) | 2014-07-24 | 2021-05-05 | Блубёрд Био, Инк. | Химерные антигенные рецепторы к bcma |
| EP3031923A1 (en) | 2014-12-11 | 2016-06-15 | Institut Pasteur | Lentiviral vector-based japanese encephalitis immunogenic composition |
| HUE056074T2 (hu) | 2014-12-12 | 2022-01-28 | 2Seventy Bio Inc | BCMA kiméra antigénreceptorok |
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| WO2017134265A1 (en) | 2016-02-05 | 2017-08-10 | Institut Pasteur | Use of inhibitors of adam12 as adjuvants in tumor therapies |
| CN108883136A (zh) | 2016-02-12 | 2018-11-23 | 蓝鸟生物公司 | Vcn增强子组合物及其使用方法 |
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| EP3452067A1 (en) | 2016-05-03 | 2019-03-13 | Wayne State University | Method of enhancing viral-mediated gene delivery in the eye using proteosome inhibitors |
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| ES2952525T3 (es) | 2016-09-08 | 2023-11-02 | 2Seventy Bio Inc | Variantes de endonucleasa homing PD-1, composiciones y métodos de uso |
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| EP0611822B1 (en) * | 1993-02-17 | 2002-05-22 | Wisconsin Alumni Research Foundation | More complex type retroviruses having mixed type LTR, and uses thereof |
| US6013516A (en) * | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| EP0885302A1 (en) * | 1996-03-05 | 1998-12-23 | The Regents Of The University Of California | Recombinant live feline immunodeficiency virus and proviral dna vaccines |
| JP2001513643A (ja) * | 1997-03-06 | 2001-09-04 | ウーベルラ、クラウス | レンチウイルスをベースとするベクター及びベクター系 |
| US20010007659A1 (en) | 1997-04-17 | 2001-07-12 | The University Of California | Use of lentiviral vectors for antigen presentation in dendritic cells |
| FR2777909B1 (fr) | 1998-04-24 | 2002-08-02 | Pasteur Institut | Utilisation de sequences d'adn de structure triplex pour le tranfert de sequences de nucleotides dans des cellules, vecteurs recombinants contenant ces sequences triplex |
| US7622300B2 (en) | 1998-06-03 | 2009-11-24 | Kappes John C | Trans-lentiviral vector particles and transduction of eukaryotic cells therewith |
| GB9825524D0 (en) | 1998-11-20 | 1999-01-13 | Oxford Biomedica Ltd | Vector |
| EP1092779B1 (en) * | 1999-10-11 | 2009-11-25 | Institut Pasteur | Lentiviral vectors for the preparation of immunotherapeutical compositions |
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| US20030194392A1 (en) | 2002-04-10 | 2003-10-16 | Pierre Charneau | Lentiviral triplex DNA, and vectors and recombinant cells containing lentiviral triplex DNA |
| US8158413B2 (en) | 2005-10-17 | 2012-04-17 | Institut Pasteur | Lentiviral vector-based vaccine |
| US8222029B2 (en) | 2005-05-16 | 2012-07-17 | Institut Pasteur | Lentiviral vector-based vaccine |
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1998
- 1998-04-24 FR FR9805197A patent/FR2777909B1/fr not_active Expired - Lifetime
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1999
- 1999-04-23 WO PCT/FR1999/000974 patent/WO1999055892A1/fr active Application Filing
- 1999-04-23 ES ES99915829T patent/ES2384553T3/es not_active Expired - Lifetime
- 1999-04-23 CA CA2326719A patent/CA2326719C/fr not_active Expired - Lifetime
- 1999-04-23 PT PT99915829T patent/PT1071804E/pt unknown
- 1999-04-23 AT AT99915829T patent/ATE553205T1/de active
- 1999-04-23 EP EP10172183.5A patent/EP2292778B1/fr not_active Expired - Lifetime
- 1999-04-23 ES ES10172183.5T patent/ES2607484T3/es not_active Expired - Lifetime
- 1999-04-23 JP JP2000546035A patent/JP4571306B2/ja not_active Expired - Lifetime
- 1999-04-23 DK DK99915829.8T patent/DK1071804T3/da active
- 1999-04-23 EP EP99915829A patent/EP1071804B1/fr not_active Expired - Lifetime
- 1999-04-23 AU AU34272/99A patent/AU3427299A/en not_active Abandoned
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2000
- 2000-10-17 US US09/688,990 patent/US6682907B1/en not_active Expired - Lifetime
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2001
- 2001-07-10 HK HK01104791.2A patent/HK1034283A1/xx not_active IP Right Cessation
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- 2003-06-25 US US10/602,663 patent/US20060040347A1/en not_active Abandoned
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- 2008-05-28 US US12/153,959 patent/US7981671B2/en not_active Expired - Fee Related
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2010
- 2010-06-10 US US12/813,375 patent/US8367068B2/en not_active Expired - Fee Related
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- 2011-09-21 US US13/238,133 patent/US8450087B2/en not_active Expired - Fee Related
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| US8460678B2 (en) | 2013-06-11 |
| AU3427299A (en) | 1999-11-16 |
| EP1071804B1 (fr) | 2012-04-11 |
| EP2292778B1 (fr) | 2016-09-14 |
| CY1112985T1 (el) | 2016-04-13 |
| PT1071804E (pt) | 2012-06-26 |
| US8367068B2 (en) | 2013-02-05 |
| US20060040347A1 (en) | 2006-02-23 |
| FR2777909A1 (fr) | 1999-10-29 |
| US20120252113A1 (en) | 2012-10-04 |
| US7981671B2 (en) | 2011-07-19 |
| US20120095083A1 (en) | 2012-04-19 |
| FR2777909B1 (fr) | 2002-08-02 |
| ATE553205T1 (de) | 2012-04-15 |
| US20100221820A1 (en) | 2010-09-02 |
| CA2326719C (fr) | 2011-04-12 |
| JP2002512804A (ja) | 2002-05-08 |
| WO1999055892A1 (fr) | 1999-11-04 |
| US8450087B2 (en) | 2013-05-28 |
| EP1071804A1 (fr) | 2001-01-31 |
| CA2326719A1 (fr) | 1999-11-04 |
| EP2292778A1 (fr) | 2011-03-09 |
| JP4571306B2 (ja) | 2010-10-27 |
| HK1034283A1 (en) | 2001-10-19 |
| US6682907B1 (en) | 2004-01-27 |
| ES2607484T3 (es) | 2017-03-31 |
| ES2384553T3 (es) | 2012-07-06 |
| US20120252114A1 (en) | 2012-10-04 |
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