MX2019014100A - Variantes de endonucleasas cblb, composiciones y metodos de uso. - Google Patents

Variantes de endonucleasas cblb, composiciones y metodos de uso.

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Publication number
MX2019014100A
MX2019014100A MX2019014100A MX2019014100A MX2019014100A MX 2019014100 A MX2019014100 A MX 2019014100A MX 2019014100 A MX2019014100 A MX 2019014100A MX 2019014100 A MX2019014100 A MX 2019014100A MX 2019014100 A MX2019014100 A MX 2019014100A
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MX
Mexico
Prior art keywords
methods
compositions
cblb
endonuclease variants
disease
Prior art date
Application number
MX2019014100A
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English (en)
Inventor
Jarjour Jordan
Havens Kyle
Rachel Krostag Anne-
Original Assignee
Bluebird Bio Inc
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Publication date
Application filed by Bluebird Bio Inc filed Critical Bluebird Bio Inc
Publication of MX2019014100A publication Critical patent/MX2019014100A/es

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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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Abstract

La presente descripción proporciona composiciones y métodos de edición genómica mejorados para la edición de un gen CBLB; la descripción proporciona además células con edición genómica para la prevención, el tratamiento o la mejora de al menos un síntoma de un cáncer, una enfermedad infecciosa, una enfermedad autoinmunitaria, una enfermedad inflamatoria o una inmunodeficiencia.
MX2019014100A 2017-05-25 2018-05-25 Variantes de endonucleasas cblb, composiciones y metodos de uso. MX2019014100A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762511194P 2017-05-25 2017-05-25
US201762567417P 2017-10-03 2017-10-03
PCT/US2018/034726 WO2018218194A1 (en) 2017-05-25 2018-05-25 Cblb endonuclease variants, compositions, and methods of use

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MX2019014100A true MX2019014100A (es) 2020-02-07

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MX2019014100A MX2019014100A (es) 2017-05-25 2018-05-25 Variantes de endonucleasas cblb, composiciones y metodos de uso.

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US (3) US20210147818A1 (es)
EP (1) EP3630962A4 (es)
JP (3) JP7191042B2 (es)
KR (2) KR20230147767A (es)
CN (1) CN110799644A (es)
AU (1) AU2018273979A1 (es)
CA (1) CA3064014A1 (es)
IL (1) IL270776A (es)
MA (1) MA48797A (es)
MX (1) MX2019014100A (es)
WO (1) WO2018218194A1 (es)

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