DK0960943T3 - Medie til dyrkning af mikroorganismer og fremgangsmåde til fremstilling af umættede fedtsyrer eller lipider indeholdende dem - Google Patents
Medie til dyrkning af mikroorganismer og fremgangsmåde til fremstilling af umættede fedtsyrer eller lipider indeholdende dem Download PDFInfo
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- DK0960943T3 DK0960943T3 DK97950433.9T DK97950433T DK0960943T3 DK 0960943 T3 DK0960943 T3 DK 0960943T3 DK 97950433 T DK97950433 T DK 97950433T DK 0960943 T3 DK0960943 T3 DK 0960943T3
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- ions
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- mortierella
- unsaturated fatty
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- 239000005642 Oleic acid Substances 0.000 description 1
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- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 108010009736 Protein Hydrolysates Proteins 0.000 description 1
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- 238000007605 air drying Methods 0.000 description 1
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- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 239000001166 ammonium sulphate Substances 0.000 description 1
- 150000008064 anhydrides Chemical class 0.000 description 1
- NGPGDYLVALNKEG-UHFFFAOYSA-N azanium;azane;2,3,4-trihydroxy-4-oxobutanoate Chemical compound [NH4+].[NH4+].[O-]C(=O)C(O)C(O)C([O-])=O NGPGDYLVALNKEG-UHFFFAOYSA-N 0.000 description 1
- 235000013527 bean curd Nutrition 0.000 description 1
- 230000003542 behavioural effect Effects 0.000 description 1
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- 239000001110 calcium chloride Substances 0.000 description 1
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- 108010079058 casein hydrolysate Proteins 0.000 description 1
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- 235000013339 cereals Nutrition 0.000 description 1
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- 238000007385 chemical modification Methods 0.000 description 1
- SIHHLZPXQLFPMC-UHFFFAOYSA-N chloroform;methanol;hydrate Chemical compound O.OC.ClC(Cl)Cl SIHHLZPXQLFPMC-UHFFFAOYSA-N 0.000 description 1
- 229910001429 cobalt ion Inorganic materials 0.000 description 1
- XLJKHNWPARRRJB-UHFFFAOYSA-N cobalt(2+) Chemical compound [Co+2] XLJKHNWPARRRJB-UHFFFAOYSA-N 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 229910001431 copper ion Inorganic materials 0.000 description 1
- 229910000366 copper(II) sulfate Inorganic materials 0.000 description 1
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- 235000012343 cottonseed oil Nutrition 0.000 description 1
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- 230000003247 decreasing effect Effects 0.000 description 1
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- 239000008121 dextrose Substances 0.000 description 1
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- 229960004132 diethyl ether Drugs 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229910000397 disodium phosphate Inorganic materials 0.000 description 1
- 229940090949 docosahexaenoic acid Drugs 0.000 description 1
- KAUVQQXNCKESLC-UHFFFAOYSA-N docosahexaenoic acid (DHA) Natural products COC(=O)C(C)NOCC1=CC=CC=C1 KAUVQQXNCKESLC-UHFFFAOYSA-N 0.000 description 1
- 125000004494 ethyl ester group Chemical group 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 235000019688 fish Nutrition 0.000 description 1
- 235000019253 formic acid Nutrition 0.000 description 1
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- 238000004108 freeze drying Methods 0.000 description 1
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- 230000008014 freezing Effects 0.000 description 1
- 235000001727 glucose Nutrition 0.000 description 1
- 150000004677 hydrates Chemical class 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 150000002617 leukotrienes Chemical class 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- ZMKDEQUXYDZSNN-UHFFFAOYSA-N linolelaidic acid Natural products CCCCCCCCC=CCC=CCCCCC(O)=O ZMKDEQUXYDZSNN-UHFFFAOYSA-N 0.000 description 1
- 235000021388 linseed oil Nutrition 0.000 description 1
- 239000000944 linseed oil Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 229960002337 magnesium chloride Drugs 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 229940050906 magnesium chloride hexahydrate Drugs 0.000 description 1
- DHRRIBDTHFBPNG-UHFFFAOYSA-L magnesium dichloride hexahydrate Chemical compound O.O.O.O.O.O.[Mg+2].[Cl-].[Cl-] DHRRIBDTHFBPNG-UHFFFAOYSA-L 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 229910052748 manganese Inorganic materials 0.000 description 1
- 239000011572 manganese Substances 0.000 description 1
- 229910001437 manganese ion Inorganic materials 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 229910001453 nickel ion Inorganic materials 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 229940038384 octadecane Drugs 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 125000001477 organic nitrogen group Chemical group 0.000 description 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 description 1
- 229960004838 phosphoric acid Drugs 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 150000003815 prostacyclins Chemical class 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108010009004 proteose-peptone Proteins 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000004153 renaturation Methods 0.000 description 1
- 210000001525 retina Anatomy 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- VWDWKYIASSYTQR-UHFFFAOYSA-N sodium nitrate Inorganic materials [Na+].[O-][N+]([O-])=O VWDWKYIASSYTQR-UHFFFAOYSA-N 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 150000003595 thromboxanes Chemical class 0.000 description 1
- 229910021654 trace metal Inorganic materials 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 125000005457 triglyceride group Chemical group 0.000 description 1
- 239000012137 tryptone Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6432—Eicosapentaenoic acids [EPA]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Botany (AREA)
- Tropical Medicine & Parasitology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34954196 | 1996-12-27 | ||
| PCT/JP1997/004898 WO1998029558A1 (fr) | 1996-12-27 | 1997-12-26 | Milieu destine a la culture de micro-organismes et procede permettant de produire des acides gras insatures ou des lipides renfermant ceux-ci |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0960943T3 true DK0960943T3 (da) | 2014-02-24 |
Family
ID=18404424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97950433.9T DK0960943T3 (da) | 1996-12-27 | 1997-12-26 | Medie til dyrkning af mikroorganismer og fremgangsmåde til fremstilling af umættede fedtsyrer eller lipider indeholdende dem |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6746857B2 (da) |
| EP (2) | EP2308988A1 (da) |
| JP (1) | JP4197744B2 (da) |
| KR (1) | KR100653107B1 (da) |
| CA (1) | CA2276179C (da) |
| DK (1) | DK0960943T3 (da) |
| ES (1) | ES2446982T3 (da) |
| PT (1) | PT960943E (da) |
| WO (1) | WO1998029558A1 (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9802561D0 (en) * | 1998-02-07 | 1998-04-01 | Zeneca Ltd | Mortierella |
| JP4088097B2 (ja) * | 2002-04-26 | 2008-05-21 | サントリー株式会社 | 高度不飽和脂肪酸含有脂質の製造方法 |
| DK3111767T3 (da) | 2002-06-19 | 2019-08-26 | Dsm Ip Assets Bv | Mikrobiel olie og fremgangsmåder til forarbejdning deraf |
| KR20140023448A (ko) * | 2002-06-19 | 2014-02-26 | 디에스엠 아이피 어셋츠 비.브이. | 다가불포화 지방산을 함유하는 미생물 오일의 제조방법 |
| KR101180594B1 (ko) * | 2003-10-02 | 2012-09-06 | 마텍 바이오싸이언스스 코포레이션 | 변형량의 염소 및 칼륨을 사용하는 미세조류 중에 고농도디에치에이의 생산 |
| US7247468B2 (en) | 2004-04-30 | 2007-07-24 | Daiso Co., Ltd. | Method for producing optically active 1,2-diols by microorganism culturing |
| DK1776450T3 (da) | 2004-08-12 | 2010-06-21 | Nippon Suisan Kaisha Ltd | Fremgangsmåde til polyumættet fedtsyreproduktion under anvendelse af hidtil ukendt cellepræservationsteknik |
| JP4849806B2 (ja) * | 2005-02-08 | 2012-01-11 | 日本水産株式会社 | 新規な菌体処理方法を用いた高度不飽和脂肪酸の製造方法 |
| US8241868B2 (en) | 2005-02-08 | 2012-08-14 | Nippon Suisan Kaisha, Ltd. | Production of polyunsaturated fatty acids using cell treatment method |
| JP2007209272A (ja) * | 2006-02-10 | 2007-08-23 | Suntory Ltd | 微生物発酵による長鎖高度不飽和脂肪酸を構成要素として含むリン脂質の製造方法 |
| US8207363B2 (en) | 2009-03-19 | 2012-06-26 | Martek Biosciences Corporation | Thraustochytrids, fatty acid compositions, and methods of making and uses thereof |
| CA2787344C (en) | 2010-01-19 | 2018-03-20 | Dsm Ip Assets B.V. | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
| KR20140057394A (ko) * | 2010-06-30 | 2014-05-12 | 닛폰 스이산 가부시키가이샤 | 유용 물질의 제조 방법 |
| US9175256B2 (en) * | 2010-12-23 | 2015-11-03 | Exxonmobil Research And Engineering Company | Production of fatty acids and fatty acid derivatives by recombinant microorganisms expressing polypeptides having lipolytic activity |
| US9222112B2 (en) | 2011-07-21 | 2015-12-29 | Dsm Ip Assets B.V. | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
| WO2013161674A1 (ja) * | 2012-04-27 | 2013-10-31 | 花王株式会社 | 乳酸の製造方法 |
| KR101439634B1 (ko) * | 2012-10-26 | 2014-09-15 | 주식회사 바이오에프디엔씨 | 항균펩타이드 베타 디펜신 3 및 그 유사체의 재조합 단백질로의 대량 생산 방법 |
| CN106755151B (zh) * | 2017-02-23 | 2021-03-23 | 内蒙古金达威药业有限公司 | 一种利用微生物发酵生产ara的方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3795585A (en) * | 1972-08-31 | 1974-03-05 | Agency Ind Science Techn | Method for manufacture of alpha-galactosidase |
| JPS5264484A (en) | 1975-11-22 | 1977-05-27 | Hiroshi Iizuka | Production of arachidonic aczd |
| JPS5822199B2 (ja) | 1981-03-03 | 1983-05-07 | 工業技術院長 | γ−リノレン酸含量の高い脂質の製造方法 |
| JPS59130191A (ja) | 1983-01-12 | 1984-07-26 | Agency Of Ind Science & Technol | γ−リノレン酸含量の高い脂質の製造方法 |
| JPS59205979A (ja) | 1983-05-11 | 1984-11-21 | Agency Of Ind Science & Technol | 微生物菌体の製造方法 |
| JPS60126091A (ja) * | 1983-12-14 | 1985-07-05 | Nisshin Oil Mills Ltd:The | γ−リノレン酸含量の高い脂質成分の製造方法 |
| EP0155420B1 (en) * | 1984-02-09 | 1988-03-23 | The Agency of Industrial Science and Technology | A method for the preparation of a fungal body and a lipid rich in gamma-linolenic acid therefrom |
| JPH0716424B2 (ja) | 1985-10-01 | 1995-03-01 | ライオン株式会社 | アラキドン酸含有脂質の製造方法 |
| JPH0761277B2 (ja) * | 1986-02-12 | 1995-07-05 | 武田薬品工業株式会社 | ▲醗▼酵法による（−）トランス−２，３−エポキシコハク酸の製造法 |
| JPH0734752B2 (ja) | 1986-03-31 | 1995-04-19 | サントリー株式会社 | アラキドン酸及びこれを含有する脂質の製造方法 |
| CA1317901C (en) | 1986-07-08 | 1993-05-18 | Yoshifumi Shinmen | Process for production of bishomo-_-linolenic acid and eicosapentaenoic acid |
| JPH0712315B2 (ja) | 1986-07-08 | 1995-02-15 | サントリー株式会社 | エイコサペンタエン酸及びこれを含有する脂質の製造方法 |
| JPH0722513B2 (ja) | 1986-07-08 | 1995-03-15 | サントリー株式会社 | ビスホモ―γ―リノレン酸及びこれを含有する脂質の製造方法 |
| JPS63133994A (ja) | 1986-11-21 | 1988-06-06 | Lion Corp | γ−リノレン酸を含有する脂質の製造方法 |
| DE3785023T3 (de) | 1987-01-28 | 1998-12-17 | Suntory Limited, Osaka | Verfahren zur Herstellung von Arachidonsäure. |
| JPS63240791A (ja) | 1987-03-27 | 1988-10-06 | Kanegafuchi Chem Ind Co Ltd | カビ類または藻類による脂質の製造法 |
| JP2582622B2 (ja) | 1987-10-27 | 1997-02-19 | 日東化学工業株式会社 | 糸状菌による高度不飽和脂肪酸の製造法 |
| JP2730081B2 (ja) | 1988-09-24 | 1998-03-25 | 日本油脂株式会社 | 微生物によるアラキドン酸含有油脂の製造方法 |
| JP2740854B2 (ja) * | 1989-07-18 | 1998-04-15 | 出光石油化学株式会社 | ジホモ―γ―リノレン酸の製造法および脂肪酸の△５位不飽和化反応抑制剤 |
| US5658767A (en) | 1991-01-24 | 1997-08-19 | Martek Corporation | Arachidonic acid and methods for the production and use thereof |
| JP3354581B2 (ja) | 1991-09-30 | 2002-12-09 | サントリー株式会社 | ジホモ−γ−リノレン酸及びこれを含有する脂質の製造方法 |
| JP3354582B2 (ja) | 1991-09-30 | 2002-12-09 | サントリー株式会社 | オメガ９系高度不飽和脂肪酸およびこれを含有する脂質の製造方法 |
| JP3354608B2 (ja) | 1992-11-16 | 2002-12-09 | サントリー株式会社 | 高度不飽和脂肪酸及びこれを含有する脂質の製造方法 |
| US5583019A (en) | 1995-01-24 | 1996-12-10 | Omegatech Inc. | Method for production of arachidonic acid |
| CA2250575C (en) * | 1996-03-28 | 2007-07-24 | Gist-Brocades B.V. | Process for the preparation of a granular microbial biomass and isolation of valuable compounds therefrom |
-
1997
- 1997-12-26 PT PT97950433T patent/PT960943E/pt unknown
- 1997-12-26 DK DK97950433.9T patent/DK0960943T3/da active
- 1997-12-26 CA CA002276179A patent/CA2276179C/en not_active Expired - Lifetime
- 1997-12-26 ES ES97950433.9T patent/ES2446982T3/es not_active Expired - Lifetime
- 1997-12-26 EP EP10181443A patent/EP2308988A1/en not_active Withdrawn
- 1997-12-26 KR KR1019997005817A patent/KR100653107B1/ko not_active IP Right Cessation
- 1997-12-26 US US09/331,759 patent/US6746857B2/en not_active Expired - Lifetime
- 1997-12-26 JP JP52987298A patent/JP4197744B2/ja not_active Expired - Lifetime
- 1997-12-26 WO PCT/JP1997/004898 patent/WO1998029558A1/ja active IP Right Grant
- 1997-12-26 EP EP97950433.9A patent/EP0960943B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0960943A4 (en) | 2004-09-08 |
| US6746857B2 (en) | 2004-06-08 |
| EP0960943A1 (en) | 1999-12-01 |
| EP2308988A1 (en) | 2011-04-13 |
| PT960943E (pt) | 2014-04-29 |
| WO1998029558A1 (fr) | 1998-07-09 |
| AU5341498A (en) | 1998-07-31 |
| JP4197744B2 (ja) | 2008-12-17 |
| AU740811B2 (en) | 2001-11-15 |
| KR20000062343A (ko) | 2000-10-25 |
| ES2446982T3 (es) | 2014-03-11 |
| CA2276179A1 (en) | 1998-07-09 |
| CA2276179C (en) | 2008-01-08 |
| EP0960943B1 (en) | 2014-02-12 |
| KR100653107B1 (ko) | 2006-12-04 |
| US20010016342A1 (en) | 2001-08-23 |
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