DK0949335T4 - Fremgangsmåde til fremstilling af en oprenset dimer af knogleafledt faktor - Google Patents

Fremgangsmåde til fremstilling af en oprenset dimer af knogleafledt faktor

Info

Publication number
DK0949335T4
DK0949335T4 DK97950371T DK97950371T DK0949335T4 DK 0949335 T4 DK0949335 T4 DK 0949335T4 DK 97950371 T DK97950371 T DK 97950371T DK 97950371 T DK97950371 T DK 97950371T DK 0949335 T4 DK0949335 T4 DK 0949335T4
Authority
DK
Denmark
Prior art keywords
preparing
derived factor
purified bone
factor dimer
dimer
Prior art date
Application number
DK97950371T
Other languages
Danish (da)
English (en)
Other versions
DK0949335T3 (da
Inventor
Jun Honda
Hidetoshi Andou
Shunjiro Sugimoto
Original Assignee
Bioph Biotech Entw Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18445882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0949335(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bioph Biotech Entw Pharm Gmbh filed Critical Bioph Biotech Entw Pharm Gmbh
Application granted granted Critical
Publication of DK0949335T3 publication Critical patent/DK0949335T3/da
Publication of DK0949335T4 publication Critical patent/DK0949335T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK97950371T 1996-12-25 1997-12-24 Fremgangsmåde til fremstilling af en oprenset dimer af knogleafledt faktor DK0949335T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP35581296 1996-12-25
PCT/JP1997/004784 WO1998029559A1 (fr) 1996-12-25 1997-12-24 Procede de preparation de dimeres purifies a partir de facteur derive de l'os

Publications (2)

Publication Number Publication Date
DK0949335T3 DK0949335T3 (da) 2004-08-30
DK0949335T4 true DK0949335T4 (da) 2009-03-23

Family

ID=18445882

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97950371T DK0949335T4 (da) 1996-12-25 1997-12-24 Fremgangsmåde til fremstilling af en oprenset dimer af knogleafledt faktor

Country Status (21)

Country Link
US (1) US6551801B1 (fr)
EP (1) EP0949335B2 (fr)
KR (1) KR20000062328A (fr)
AP (1) AP9901539A0 (fr)
AT (1) ATE266095T1 (fr)
AU (1) AU5339598A (fr)
BR (1) BR9714183A (fr)
CA (1) CA2275464A1 (fr)
DE (1) DE69728997T3 (fr)
DK (1) DK0949335T4 (fr)
EA (1) EA199900596A1 (fr)
ES (1) ES2216181T5 (fr)
HU (1) HUP0002573A2 (fr)
IL (1) IL130641A0 (fr)
NO (1) NO993151D0 (fr)
PL (1) PL334303A1 (fr)
PT (1) PT949335E (fr)
SI (1) SI0949335T2 (fr)
TR (1) TR199901479T2 (fr)
WO (1) WO1998029559A1 (fr)
ZA (1) ZA9711580B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7811793B2 (en) * 1996-12-25 2010-10-12 Biopharma Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh Process for preparing purified active monomer of bone-derived factor
US20040019185A1 (en) * 1996-12-25 2004-01-29 Hidetoshi Andou Process for preparing purified active monomer of bone-derived factor
EP1273655A4 (fr) * 2000-03-30 2004-08-04 Takeda Chemical Industries Ltd Procede de production de proteine de recombinaison
AU2003209071B2 (en) * 2002-02-08 2008-08-14 The University Of Erlangen-Nuremberg Formulation comprising bioactive agents and method of using same
EP1542711A4 (fr) * 2002-08-13 2009-07-01 Wyeth Corp Peptides utilises en tant qu'excipients de solubilisation pour la transformation des proteines du facteur de croissance
JP4800739B2 (ja) * 2005-10-20 2011-10-26 デンカ生研株式会社 アッセイ用媒体及びアッセイ方法
JP5386354B2 (ja) * 2006-09-08 2014-01-15 ワイス・エルエルシー アフィニティークロマトグラフィーを使用するタンパク質精製におけるアルギニン洗浄
AU2007234612B2 (en) * 2006-12-14 2013-06-27 Johnson & Johnson Regenerative Therapeutics, Llc Protein stabilization formulations
US7678764B2 (en) 2007-06-29 2010-03-16 Johnson & Johnson Regenerative Therapeutics, Llc Protein formulations for use at elevated temperatures
JP5323832B2 (ja) 2007-08-07 2013-10-23 アドバンスト・テクノロジーズ・アンド・リジェネレイティブ・メディスン・エルエルシー 酸性水溶液中にｇｄｆ−５を含むタンパク質製剤
US7947649B2 (en) * 2008-04-14 2011-05-24 Advanced Technologies And Regenerative Medicine, Llc Liquid buffered GDF-5 formulations
US8398611B2 (en) 2010-12-28 2013-03-19 Depuy Mitek, Inc. Compositions and methods for treating joints
US8455436B2 (en) 2010-12-28 2013-06-04 Depuy Mitek, Llc Compositions and methods for treating joints
US8524662B2 (en) 2010-12-28 2013-09-03 Depuy Mitek, Llc Compositions and methods for treating joints
US8623839B2 (en) 2011-06-30 2014-01-07 Depuy Mitek, Llc Compositions and methods for stabilized polysaccharide formulations
US9682099B2 (en) 2015-01-20 2017-06-20 DePuy Synthes Products, Inc. Compositions and methods for treating joints

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1225225A3 (fr) * 1988-04-08 2003-01-08 Stryker Corporation Dispositifs ostéogéniques
ATE287949T1 (de) * 1992-07-31 2005-02-15 Stryker Corp Löslicher komplex morphogener proteine und zusammensetzungen davon
JP3570558B2 (ja) * 1993-05-01 2004-09-29 持田製薬株式会社 Ｄｎａ断片およびそれを含むベクター、該ベクターによって形質転換された形質転換体、該ベクターを用いる蛋白質の産生方法
US5385887A (en) * 1993-09-10 1995-01-31 Genetics Institute, Inc. Formulations for delivery of osteogenic proteins
US5399677A (en) * 1993-12-07 1995-03-21 Genetics Institute, Inc. Mutants of bone morphogenetic proteins
US5702637A (en) 1995-04-19 1997-12-30 Minnesota Mining And Manufacturing Company Liquid crystal compounds having a chiral fluorinated terminal portion
PL186518B1 (pl) * 1995-04-19 2004-01-30 Bioph Biotech Entw Pharm Gmbh Białko, kompozycja farmaceutyczna i sposób wytwarzania białka

Also Published As

Publication number Publication date
KR20000062328A (ko) 2000-10-25
SI0949335T1 (en) 2004-10-31
ATE266095T1 (de) 2004-05-15
EP0949335B2 (fr) 2008-11-19
PT949335E (pt) 2004-09-30
DE69728997T2 (de) 2004-09-02
EP0949335A4 (fr) 2003-01-22
ZA9711580B (en) 1999-09-23
TR199901479T2 (xx) 1999-09-21
HUP0002573A2 (hu) 2000-12-28
EP0949335A1 (fr) 1999-10-13
BR9714183A (pt) 2000-02-29
NO993151L (no) 1999-06-24
DE69728997T3 (de) 2009-07-09
DE69728997D1 (de) 2004-06-09
CA2275464A1 (fr) 1998-07-09
ES2216181T3 (es) 2004-10-16
AP9901539A0 (en) 1999-06-30
NO993151D0 (no) 1999-06-24
EA199900596A1 (ru) 2000-02-28
DK0949335T3 (da) 2004-08-30
SI0949335T2 (sl) 2009-04-30
AU5339598A (en) 1998-07-31
US6551801B1 (en) 2003-04-22
ES2216181T5 (es) 2009-03-01
IL130641A0 (en) 2000-06-01
WO1998029559A1 (fr) 1998-07-09
EP0949335B1 (fr) 2004-05-06
PL334303A1 (en) 2000-02-14

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