DK0949335T4 - Fremgangsmåde til fremstilling af en oprenset dimer af knogleafledt faktor - Google Patents
Fremgangsmåde til fremstilling af en oprenset dimer af knogleafledt faktorInfo
- Publication number
- DK0949335T4 DK0949335T4 DK97950371T DK97950371T DK0949335T4 DK 0949335 T4 DK0949335 T4 DK 0949335T4 DK 97950371 T DK97950371 T DK 97950371T DK 97950371 T DK97950371 T DK 97950371T DK 0949335 T4 DK0949335 T4 DK 0949335T4
- Authority
- DK
- Denmark
- Prior art keywords
- preparing
- derived factor
- purified bone
- factor dimer
- dimer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP35581296 | 1996-12-25 | ||
| PCT/JP1997/004784 WO1998029559A1 (fr) | 1996-12-25 | 1997-12-24 | Procede de preparation de dimeres purifies a partir de facteur derive de l'os |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK0949335T3 DK0949335T3 (da) | 2004-08-30 |
| DK0949335T4 true DK0949335T4 (da) | 2009-03-23 |
Family
ID=18445882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97950371T DK0949335T4 (da) | 1996-12-25 | 1997-12-24 | Fremgangsmåde til fremstilling af en oprenset dimer af knogleafledt faktor |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6551801B1 (da) |
| EP (1) | EP0949335B2 (da) |
| KR (1) | KR20000062328A (da) |
| AP (1) | AP9901539A0 (da) |
| AT (1) | ATE266095T1 (da) |
| AU (1) | AU5339598A (da) |
| BR (1) | BR9714183A (da) |
| CA (1) | CA2275464A1 (da) |
| DE (1) | DE69728997T3 (da) |
| DK (1) | DK0949335T4 (da) |
| EA (1) | EA199900596A1 (da) |
| ES (1) | ES2216181T5 (da) |
| HU (1) | HUP0002573A2 (da) |
| IL (1) | IL130641A0 (da) |
| NO (1) | NO993151D0 (da) |
| PL (1) | PL334303A1 (da) |
| PT (1) | PT949335E (da) |
| SI (1) | SI0949335T2 (da) |
| TR (1) | TR199901479T2 (da) |
| WO (1) | WO1998029559A1 (da) |
| ZA (1) | ZA9711580B (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040019185A1 (en) * | 1996-12-25 | 2004-01-29 | Hidetoshi Andou | Process for preparing purified active monomer of bone-derived factor |
| US7811793B2 (en) * | 1996-12-25 | 2010-10-12 | Biopharma Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh | Process for preparing purified active monomer of bone-derived factor |
| US20030120042A1 (en) * | 2000-03-30 | 2003-06-26 | Takao Yamada | Process for producing recombinant protein |
| CA2474919A1 (en) * | 2002-02-08 | 2003-08-14 | Wyeth | Formulation comprising bioactive agents and method of using same |
| JP2006508049A (ja) * | 2002-08-13 | 2006-03-09 | ワイエス | 増殖因子βタンパク質を形質転換するための可溶化賦形剤としてのペプチド |
| JP4800739B2 (ja) * | 2005-10-20 | 2011-10-26 | デンカ生研株式会社 | アッセイ用媒体及びアッセイ方法 |
| AR062711A1 (es) * | 2006-09-08 | 2008-11-26 | Wyeth Corp | Lavado de arginina en l a purificacion de proteinas usando cromatografia de afinidad |
| AU2007234612B2 (en) * | 2006-12-14 | 2013-06-27 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein stabilization formulations |
| US7678764B2 (en) | 2007-06-29 | 2010-03-16 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein formulations for use at elevated temperatures |
| WO2009020744A1 (en) | 2007-08-07 | 2009-02-12 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein formulations comprising gdf-5 in aqueous acidic solution |
| BRPI0911048A2 (pt) * | 2008-04-14 | 2015-12-29 | Atrm Llc | formulações líquidas tamponadas de gdf-5 |
| US8455436B2 (en) | 2010-12-28 | 2013-06-04 | Depuy Mitek, Llc | Compositions and methods for treating joints |
| US8398611B2 (en) | 2010-12-28 | 2013-03-19 | Depuy Mitek, Inc. | Compositions and methods for treating joints |
| US8524662B2 (en) | 2010-12-28 | 2013-09-03 | Depuy Mitek, Llc | Compositions and methods for treating joints |
| US8623839B2 (en) | 2011-06-30 | 2014-01-07 | Depuy Mitek, Llc | Compositions and methods for stabilized polysaccharide formulations |
| US9682099B2 (en) | 2015-01-20 | 2017-06-20 | DePuy Synthes Products, Inc. | Compositions and methods for treating joints |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68929472T2 (de) * | 1988-04-08 | 2004-05-13 | Stryker Corp., Kalamazoo | Biosynthetische knochenbildende Proteine, und sie enthaltende knochenbildende Vorrichtungen |
| AU678380B2 (en) * | 1992-07-31 | 1997-05-29 | Stryker Corporation | Morphogenic protein soluble complex and composition thereof |
| JP3570558B2 (ja) * | 1993-05-01 | 2004-09-29 | 持田製薬株式会社 | Ｄｎａ断片およびそれを含むベクター、該ベクターによって形質転換された形質転換体、該ベクターを用いる蛋白質の産生方法 |
| US5385887A (en) * | 1993-09-10 | 1995-01-31 | Genetics Institute, Inc. | Formulations for delivery of osteogenic proteins |
| US5399677A (en) * | 1993-12-07 | 1995-03-21 | Genetics Institute, Inc. | Mutants of bone morphogenetic proteins |
| US5702637A (en) * | 1995-04-19 | 1997-12-30 | Minnesota Mining And Manufacturing Company | Liquid crystal compounds having a chiral fluorinated terminal portion |
| US7235527B2 (en) * | 1995-04-19 | 2007-06-26 | Biopharm Gesellschaft Zur Biotechnologieschen Entwicklung Von Pharmaka Mbh | Protein and process for producing the same |
-
1997
- 1997-12-23 ZA ZA9711580A patent/ZA9711580B/xx unknown
- 1997-12-24 DE DE69728997T patent/DE69728997T3/de not_active Expired - Lifetime
- 1997-12-24 AT AT97950371T patent/ATE266095T1/de active
- 1997-12-24 PT PT97950371T patent/PT949335E/pt unknown
- 1997-12-24 BR BR9714183-6A patent/BR9714183A/pt not_active IP Right Cessation
- 1997-12-24 EP EP97950371A patent/EP0949335B2/en not_active Expired - Lifetime
- 1997-12-24 US US09/331,948 patent/US6551801B1/en not_active Expired - Fee Related
- 1997-12-24 CA CA002275464A patent/CA2275464A1/en not_active Abandoned
- 1997-12-24 AU AU53395/98A patent/AU5339598A/en not_active Abandoned
- 1997-12-24 TR TR1999/01479T patent/TR199901479T2/xx unknown
- 1997-12-24 HU HU0002573A patent/HUP0002573A2/hu unknown
- 1997-12-24 IL IL13064197A patent/IL130641A0/xx unknown
- 1997-12-24 SI SI9730664T patent/SI0949335T2/sl unknown
- 1997-12-24 WO PCT/JP1997/004784 patent/WO1998029559A1/ja not_active Ceased
- 1997-12-24 PL PL97334303A patent/PL334303A1/xx unknown
- 1997-12-24 AP APAP/P/1999/001539A patent/AP9901539A0/en unknown
- 1997-12-24 KR KR1019997005776A patent/KR20000062328A/ko not_active Withdrawn
- 1997-12-24 EA EA199900596A patent/EA199900596A1/ru unknown
- 1997-12-24 ES ES97950371T patent/ES2216181T5/es not_active Expired - Lifetime
- 1997-12-24 DK DK97950371T patent/DK0949335T4/da active
-
1999
- 1999-06-24 NO NO993151A patent/NO993151D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SI0949335T1 (en) | 2004-10-31 |
| TR199901479T2 (xx) | 1999-09-21 |
| EA199900596A1 (ru) | 2000-02-28 |
| US6551801B1 (en) | 2003-04-22 |
| CA2275464A1 (en) | 1998-07-09 |
| DE69728997D1 (de) | 2004-06-09 |
| EP0949335B2 (en) | 2008-11-19 |
| ES2216181T5 (es) | 2009-03-01 |
| WO1998029559A1 (fr) | 1998-07-09 |
| SI0949335T2 (sl) | 2009-04-30 |
| AU5339598A (en) | 1998-07-31 |
| HUP0002573A2 (hu) | 2000-12-28 |
| EP0949335B1 (en) | 2004-05-06 |
| IL130641A0 (en) | 2000-06-01 |
| NO993151L (no) | 1999-06-24 |
| PT949335E (pt) | 2004-09-30 |
| ATE266095T1 (de) | 2004-05-15 |
| NO993151D0 (no) | 1999-06-24 |
| BR9714183A (pt) | 2000-02-29 |
| DE69728997T2 (de) | 2004-09-02 |
| EP0949335A4 (en) | 2003-01-22 |
| EP0949335A1 (en) | 1999-10-13 |
| DK0949335T3 (da) | 2004-08-30 |
| PL334303A1 (en) | 2000-02-14 |
| AP9901539A0 (en) | 1999-06-30 |
| DE69728997T3 (de) | 2009-07-09 |
| ES2216181T3 (es) | 2004-10-16 |
| ZA9711580B (en) | 1999-09-23 |
| KR20000062328A (ko) | 2000-10-25 |
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