DK0945454T3 - Iminochlorin-asparaginsyrederivater - Google Patents

Iminochlorin-asparaginsyrederivater

Info

Publication number
DK0945454T3
DK0945454T3 DK97941282T DK97941282T DK0945454T3 DK 0945454 T3 DK0945454 T3 DK 0945454T3 DK 97941282 T DK97941282 T DK 97941282T DK 97941282 T DK97941282 T DK 97941282T DK 0945454 T3 DK0945454 T3 DK 0945454T3
Authority
DK
Denmark
Prior art keywords
aspartic acid
acid derivatives
present
iminochlorin
iminochlorin aspartic
Prior art date
Application number
DK97941282T
Other languages
Danish (da)
English (en)
Inventor
Muneo Hikida
Masahiko Mori
Isao Sakata
Susumu Nakajima
Hiroyuki Takata
Original Assignee
Wyeth Lederle Japan Ltd
Photochemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Lederle Japan Ltd, Photochemical Co Ltd filed Critical Wyeth Lederle Japan Ltd
Application granted granted Critical
Publication of DK0945454T3 publication Critical patent/DK0945454T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK97941282T 1996-10-01 1997-09-30 Iminochlorin-asparaginsyrederivater DK0945454T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP27861196 1996-10-01
PCT/JP1997/003484 WO1998014453A1 (fr) 1996-10-01 1997-09-30 Derives d'acide iminochlorinaspartique

Publications (1)

Publication Number Publication Date
DK0945454T3 true DK0945454T3 (da) 2003-10-27

Family

ID=17599698

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97941282T DK0945454T3 (da) 1996-10-01 1997-09-30 Iminochlorin-asparaginsyrederivater

Country Status (12)

Country Link
US (1) US6063777A (de)
EP (1) EP0945454B1 (de)
JP (1) JP3613599B2 (de)
KR (1) KR100463478B1 (de)
AT (1) ATE244244T1 (de)
AU (1) AU713059B2 (de)
CA (1) CA2268968C (de)
DE (1) DE69723298T2 (de)
DK (1) DK0945454T3 (de)
ES (1) ES2202640T3 (de)
PT (1) PT945454E (de)
WO (1) WO1998014453A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060212025A1 (en) 1998-11-30 2006-09-21 Light Bioscience, Llc Method and apparatus for acne treatment
US9192780B2 (en) 1998-11-30 2015-11-24 L'oreal Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders
US6887260B1 (en) 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
JP2002534483A (ja) * 1999-01-15 2002-10-15 ライト サイエンシーズ コーポレイション 代謝性骨障害または骨転移のための治療的組成物
US20030114434A1 (en) * 1999-08-31 2003-06-19 James Chen Extended duration light activated cancer therapy
KR100748908B1 (ko) * 1999-11-30 2007-08-13 가부시키가이샤 히까리케미카루겡뀨쇼 포르피린 화합물
US7897140B2 (en) 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
US7753943B2 (en) * 2001-02-06 2010-07-13 Qlt Inc. Reduced fluence rate PDT
ES2304429T3 (es) 2001-02-06 2008-10-16 Qlt Inc. Terapia fotodinamica con indice de fluencia reducido.
JP2005527493A (ja) * 2002-01-23 2005-09-15 ライト サイエンシーズ コーポレイション 光線力学療法のためのシステムおよび方法
JP4394334B2 (ja) * 2002-06-25 2010-01-06 浜松ホトニクス株式会社 脈管病に関する光物理化学的診断・治療薬
DE60328496D1 (en) 2002-06-27 2009-09-03 Health Research Inc Fluorinierte chlorin und bacteriochlorin photosensitizer für fotodynamische therapie
IL152900A0 (en) * 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
US20060282132A1 (en) * 2003-06-20 2006-12-14 Keio University Photodynamic therapy equipment, method for controlling photodynamic therapy equipment and method of photodynamic method
CN101247768A (zh) 2003-07-31 2008-08-20 莱特生物科学有限公司 用于光动力学治疗烧伤、创伤和相关皮肤病的系统和方法
JPWO2006085517A1 (ja) * 2005-02-08 2008-06-26 株式会社光ケミカル研究所 クロリン類及びポルフィリン類のｐｄｔ用軟膏製剤及び坐剤
JP2006306743A (ja) * 2005-04-26 2006-11-09 Hamamatsu Photonics Kk 体液処理方法
JP5179245B2 (ja) * 2008-04-30 2013-04-10 功 阪田 皮膚疾患治療剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS625986A (ja) * 1985-04-30 1987-01-12 Nippon Petrochem Co Ltd 新規なテトラピロ−ル化合物
JP3191223B2 (ja) * 1991-10-04 2001-07-23 株式会社光ケミカル研究所 ポルフィリン誘導体とその用途
JP3450399B2 (ja) * 1993-12-28 2003-09-22 大鵬薬品工業株式会社 血管新生阻害剤
JP3718887B2 (ja) * 1995-10-30 2005-11-24 株式会社光ケミカル研究所 ポルフィリン誘導体とその用途
US5770730A (en) * 1996-03-08 1998-06-23 Health Research, Inc. Synthesis of carbodimide analogs of chlorins and bacteriochlorins and their use for diagnosis and treatment of cancer

Also Published As

Publication number Publication date
AU4322997A (en) 1998-04-24
KR20000048843A (ko) 2000-07-25
DE69723298T2 (de) 2004-02-05
CA2268968C (en) 2006-10-10
EP0945454A1 (de) 1999-09-29
KR100463478B1 (ko) 2004-12-29
CA2268968A1 (en) 1998-04-09
AU713059B2 (en) 1999-11-25
DE69723298D1 (de) 2003-08-07
EP0945454A4 (de) 1999-11-24
WO1998014453A1 (fr) 1998-04-09
JP3613599B2 (ja) 2005-01-26
PT945454E (pt) 2003-11-28
ES2202640T3 (es) 2004-04-01
EP0945454B1 (de) 2003-07-02
US6063777A (en) 2000-05-16
ATE244244T1 (de) 2003-07-15

Similar Documents

Publication Publication Date Title
DE69723298D1 (de) Iminochlorinasparaginsaeure-derivate
ATE252529T1 (de) Colchinolderivate als gefässschädigende mittel
ES2191260T3 (es) Derivados de la imidazolidin-4-ona utiles como agentes anticancerosos.
EA200100766A1 (ru) Хинолин-2-он замещенные гетероарильные производные, используемые в качестве противоопухолевых агентов
DE69922216D1 (de) Porphyrin derivate, ihre verwendung in der photodynamischen therapie und diese enthaltende medizinische geräte
NO943524D0 (no) Fremgangsmåte for behandling av tumor
IT1229570B (it) Derivati fluorurati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.
IT1137640B (it) Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
PT1104759E (pt) Compostos heteroaril-fenil-pirazole como agentes anti-inflamatorios e analgesicos
CA2335514A1 (en) Alkyl ether analogs of chlorins having an n-substituted imide ring
ATE359786T1 (de) Camptothecin derivate
BRPI9916096B8 (pt) derivados de bacterioclorofila substituídos com paládio, processos para sua preparação, composição compreendendo esses derivados e seu uso.
IT1229569B (it) Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.
DK196688A (da) Bicykliske forbindelser og fremgangsmaade til fremstilling deraf
NO20052360L (no) Forbedrede formuleringer inneholdende substituerte imidazolderivater
AU773261B2 (en) Porphyrin compound
FI801769A (fi) Paromomycin-derivat foerfarande foer deras framstaellning och terapeutiska kompositioner daer de ingaor
DK0986393T3 (da) Anvendelse af et nitroxid eller et prodrug heraf ved profylaktisk og terapeutisk behandling af cancer
US4965064A (en) Pheophorbide derivatives
TR199801398T2 (xx) Ast�m� tedavi edici maddeler
GB8405113D0 (en) N-arylpiperazine derivatives
RU2217426C2 (ru) Цианиминохиноксалиновые производные, способ их получения (варианты), промежуточные соединения и фармацевтическая композиция
NO803862L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive fenylaminoimidazolin-derivater
RU99128088A (ru) Цианоамиды, как ингибиторы пролиферации клеток