DK0934278T3 - Bis(acridincarboxamid) og bis(phenazincarboxamid) som antitumormidler - Google Patents

Bis(acridincarboxamid) og bis(phenazincarboxamid) som antitumormidler

Info

Publication number
DK0934278T3
DK0934278T3 DK97909456T DK97909456T DK0934278T3 DK 0934278 T3 DK0934278 T3 DK 0934278T3 DK 97909456 T DK97909456 T DK 97909456T DK 97909456 T DK97909456 T DK 97909456T DK 0934278 T3 DK0934278 T3 DK 0934278T3
Authority
DK
Denmark
Prior art keywords
bis
carboxamide
pct
alkyl
different
Prior art date
Application number
DK97909456T
Other languages
Danish (da)
English (en)
Inventor
William Alexander Denny
Swarnalatha A Gamage
Julie Ann Spicer
Bruce Charles Baguley
Graeme John Finlay
Original Assignee
Xenova Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenova Ltd filed Critical Xenova Ltd
Application granted granted Critical
Publication of DK0934278T3 publication Critical patent/DK0934278T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polishing Bodies And Polishing Tools (AREA)
  • Multicomponent Fibers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Liquid Crystal (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK97909456T 1996-10-18 1997-10-17 Bis(acridincarboxamid) og bis(phenazincarboxamid) som antitumormidler DK0934278T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9621795.5A GB9621795D0 (en) 1996-10-18 1996-10-18 Pharmaceutical compounds
PCT/GB1997/002886 WO1998017650A1 (en) 1996-10-18 1997-10-17 Bis(acridinecarboxamide) and bis(phenazinecarboxamide) as antitumour agents

Publications (1)

Publication Number Publication Date
DK0934278T3 true DK0934278T3 (da) 2003-01-06

Family

ID=10801674

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97909456T DK0934278T3 (da) 1996-10-18 1997-10-17 Bis(acridincarboxamid) og bis(phenazincarboxamid) som antitumormidler

Country Status (29)

Country Link
US (1) US6114332A (cs)
EP (1) EP0934278B1 (cs)
JP (1) JP2001503399A (cs)
KR (1) KR20000049252A (cs)
CN (1) CN1116285C (cs)
AT (1) ATE223381T1 (cs)
AU (1) AU717724B2 (cs)
BG (1) BG64555B1 (cs)
BR (1) BR9711948A (cs)
CA (1) CA2268411C (cs)
CZ (1) CZ295302B6 (cs)
DE (1) DE69715230T2 (cs)
DK (1) DK0934278T3 (cs)
ES (1) ES2183142T3 (cs)
GB (2) GB9621795D0 (cs)
HU (1) HU221953B1 (cs)
ID (1) ID22444A (cs)
MY (1) MY122017A (cs)
NO (1) NO313381B1 (cs)
NZ (1) NZ335055A (cs)
PL (1) PL193669B1 (cs)
PT (1) PT934278E (cs)
RO (1) RO120636B1 (cs)
RU (1) RU2179972C2 (cs)
SK (1) SK285121B6 (cs)
TW (1) TW432060B (cs)
UA (1) UA67729C2 (cs)
WO (1) WO1998017650A1 (cs)
ZA (2) ZA979331B (cs)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6974878B2 (en) 2001-03-21 2005-12-13 Symyx Technologies, Inc. Catalyst ligands, catalytic metal complexes and processes using same
EP1131283A1 (en) * 1999-09-10 2001-09-12 Symyx Technologies Catalyst ligands, catalytic metal complexes and processes using and methods of making same
AU2003300720A1 (en) * 2003-12-31 2005-07-21 Council Of Scientific And Industrial Research C-8 linked pyrrolo(2,1-c)(1,4)benzodiazepine-acridone/acridine hybrids
US9856225B2 (en) * 2013-12-24 2018-01-02 University Of Florida Research Foundation, Incorporated Substituted phenazines as antimicrobial agents
CN104961801B (zh) * 2015-07-13 2018-01-19 兰州大学 一种具有多靶点的抗菌多肽偶联物及其二聚物的合成和应用
CN106554321B (zh) * 2015-09-25 2019-05-28 陆源 一种吩嗪类物质、其制备方法及其应用
US20240279204A1 (en) * 2021-12-09 2024-08-22 Korea Institute Of Ocean Science & Technology Novel diphenazine compound, and use thereof for preventing or treating cancer or neuroinflammatory diseases
WO2025043616A1 (zh) * 2023-08-31 2025-03-06 侯明宏 吖啶类衍生物用于抗癌的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201084A (en) * 1982-06-25 1985-10-11 New Zealand Dev Finance 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such
EP0172744A2 (en) * 1984-08-16 1986-02-26 Development Finance Corporation Of New Zealand Phenazinecarboxamide compounds
IT1293525B1 (it) * 1997-08-01 1999-03-01 Uni Degli Studi Camerino Bis-acridincarbossiammidi aventi attivita' antitumorale

Also Published As

Publication number Publication date
ZA979331B (en) 1998-05-21
DE69715230D1 (de) 2002-10-10
HUP9902883A3 (en) 2001-01-29
ID22444A (id) 1999-10-14
AU4713797A (en) 1998-05-15
ZA979328B (en) 1998-07-06
CZ295302B6 (cs) 2005-07-13
BR9711948A (pt) 1999-08-24
PL193669B1 (pl) 2007-03-30
RU2179972C2 (ru) 2002-02-27
NO991833L (no) 1999-06-03
GB9908192D0 (en) 1999-06-02
ATE223381T1 (de) 2002-09-15
CN1240430A (zh) 2000-01-05
US6114332A (en) 2000-09-05
CA2268411A1 (en) 1998-04-30
PT934278E (pt) 2003-01-31
NO991833D0 (no) 1999-04-16
WO1998017650A1 (en) 1998-04-30
SK50499A3 (en) 2000-05-16
EP0934278A1 (en) 1999-08-11
KR20000049252A (ko) 2000-07-25
CN1116285C (zh) 2003-07-30
CZ127199A3 (cs) 1999-09-15
GB9621795D0 (en) 1996-12-11
AU717724B2 (en) 2000-03-30
RO120636B1 (ro) 2006-05-30
ES2183142T3 (es) 2003-03-16
EP0934278B1 (en) 2002-09-04
GB2334032B (en) 2000-11-08
NO313381B1 (no) 2002-09-23
PL332877A1 (en) 1999-10-25
SK285121B6 (sk) 2006-06-01
JP2001503399A (ja) 2001-03-13
BG103329A (en) 2000-11-30
TW432060B (en) 2001-05-01
CA2268411C (en) 2008-07-22
DE69715230T2 (de) 2009-09-17
NZ335055A (en) 2000-09-29
UA67729C2 (uk) 2004-07-15
MY122017A (en) 2006-03-31
BG64555B1 (bg) 2005-07-29
HK1018773A1 (en) 2000-01-07
GB2334032A (en) 1999-08-11
HU221953B1 (hu) 2003-03-28

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