BG64555B1 - Бис(акридинкарбоксамид) и бис(феназинкарбоксамид) като антитуморни агенти - Google Patents

Бис(акридинкарбоксамид) и бис(феназинкарбоксамид) като антитуморни агенти Download PDF

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Publication number
BG64555B1
BG64555B1 BG103329A BG10332999A BG64555B1 BG 64555 B1 BG64555 B1 BG 64555B1 BG 103329 A BG103329 A BG 103329A BG 10332999 A BG10332999 A BG 10332999A BG 64555 B1 BG64555 B1 BG 64555B1
Authority
BG
Bulgaria
Prior art keywords
arh
bis
nmr
compound
nch
Prior art date
Application number
BG103329A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG103329A (en
Inventor
William Denny
Swarnalatha Gamage
Julie SPICER
Bruce Baguley
Greame FINLAY
Original Assignee
Xenova Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenova Limited filed Critical Xenova Limited
Publication of BG103329A publication Critical patent/BG103329A/xx
Publication of BG64555B1 publication Critical patent/BG64555B1/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polishing Bodies And Polishing Tools (AREA)
  • Multicomponent Fibers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Liquid Crystal (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BG103329A 1996-10-18 1999-04-13 Бис(акридинкарбоксамид) и бис(феназинкарбоксамид) като антитуморни агенти BG64555B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9621795.5A GB9621795D0 (en) 1996-10-18 1996-10-18 Pharmaceutical compounds

Publications (2)

Publication Number Publication Date
BG103329A BG103329A (en) 2000-11-30
BG64555B1 true BG64555B1 (bg) 2005-07-29

Family

ID=10801674

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103329A BG64555B1 (bg) 1996-10-18 1999-04-13 Бис(акридинкарбоксамид) и бис(феназинкарбоксамид) като антитуморни агенти

Country Status (29)

Country Link
US (1) US6114332A (cs)
EP (1) EP0934278B1 (cs)
JP (1) JP2001503399A (cs)
KR (1) KR20000049252A (cs)
CN (1) CN1116285C (cs)
AT (1) ATE223381T1 (cs)
AU (1) AU717724B2 (cs)
BG (1) BG64555B1 (cs)
BR (1) BR9711948A (cs)
CA (1) CA2268411C (cs)
CZ (1) CZ295302B6 (cs)
DE (1) DE69715230T2 (cs)
DK (1) DK0934278T3 (cs)
ES (1) ES2183142T3 (cs)
GB (2) GB9621795D0 (cs)
HU (1) HU221953B1 (cs)
ID (1) ID22444A (cs)
MY (1) MY122017A (cs)
NO (1) NO313381B1 (cs)
NZ (1) NZ335055A (cs)
PL (1) PL193669B1 (cs)
PT (1) PT934278E (cs)
RO (1) RO120636B1 (cs)
RU (1) RU2179972C2 (cs)
SK (1) SK285121B6 (cs)
TW (1) TW432060B (cs)
UA (1) UA67729C2 (cs)
WO (1) WO1998017650A1 (cs)
ZA (2) ZA979331B (cs)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6974878B2 (en) 2001-03-21 2005-12-13 Symyx Technologies, Inc. Catalyst ligands, catalytic metal complexes and processes using same
EP1131283A1 (en) * 1999-09-10 2001-09-12 Symyx Technologies Catalyst ligands, catalytic metal complexes and processes using and methods of making same
AU2003300720A1 (en) * 2003-12-31 2005-07-21 Council Of Scientific And Industrial Research C-8 linked pyrrolo(2,1-c)(1,4)benzodiazepine-acridone/acridine hybrids
US9856225B2 (en) * 2013-12-24 2018-01-02 University Of Florida Research Foundation, Incorporated Substituted phenazines as antimicrobial agents
CN104961801B (zh) * 2015-07-13 2018-01-19 兰州大学 一种具有多靶点的抗菌多肽偶联物及其二聚物的合成和应用
CN106554321B (zh) * 2015-09-25 2019-05-28 陆源 一种吩嗪类物质、其制备方法及其应用
US20240279204A1 (en) * 2021-12-09 2024-08-22 Korea Institute Of Ocean Science & Technology Novel diphenazine compound, and use thereof for preventing or treating cancer or neuroinflammatory diseases
WO2025043616A1 (zh) * 2023-08-31 2025-03-06 侯明宏 吖啶类衍生物用于抗癌的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201084A (en) * 1982-06-25 1985-10-11 New Zealand Dev Finance 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such
EP0172744A2 (en) * 1984-08-16 1986-02-26 Development Finance Corporation Of New Zealand Phenazinecarboxamide compounds
IT1293525B1 (it) * 1997-08-01 1999-03-01 Uni Degli Studi Camerino Bis-acridincarbossiammidi aventi attivita' antitumorale

Also Published As

Publication number Publication date
ZA979331B (en) 1998-05-21
DE69715230D1 (de) 2002-10-10
HUP9902883A3 (en) 2001-01-29
ID22444A (id) 1999-10-14
AU4713797A (en) 1998-05-15
ZA979328B (en) 1998-07-06
CZ295302B6 (cs) 2005-07-13
BR9711948A (pt) 1999-08-24
PL193669B1 (pl) 2007-03-30
RU2179972C2 (ru) 2002-02-27
NO991833L (no) 1999-06-03
GB9908192D0 (en) 1999-06-02
ATE223381T1 (de) 2002-09-15
CN1240430A (zh) 2000-01-05
US6114332A (en) 2000-09-05
CA2268411A1 (en) 1998-04-30
PT934278E (pt) 2003-01-31
NO991833D0 (no) 1999-04-16
WO1998017650A1 (en) 1998-04-30
SK50499A3 (en) 2000-05-16
DK0934278T3 (da) 2003-01-06
EP0934278A1 (en) 1999-08-11
KR20000049252A (ko) 2000-07-25
CN1116285C (zh) 2003-07-30
CZ127199A3 (cs) 1999-09-15
GB9621795D0 (en) 1996-12-11
AU717724B2 (en) 2000-03-30
RO120636B1 (ro) 2006-05-30
ES2183142T3 (es) 2003-03-16
EP0934278B1 (en) 2002-09-04
GB2334032B (en) 2000-11-08
NO313381B1 (no) 2002-09-23
PL332877A1 (en) 1999-10-25
SK285121B6 (sk) 2006-06-01
JP2001503399A (ja) 2001-03-13
BG103329A (en) 2000-11-30
TW432060B (en) 2001-05-01
CA2268411C (en) 2008-07-22
DE69715230T2 (de) 2009-09-17
NZ335055A (en) 2000-09-29
UA67729C2 (uk) 2004-07-15
MY122017A (en) 2006-03-31
HK1018773A1 (en) 2000-01-07
GB2334032A (en) 1999-08-11
HU221953B1 (hu) 2003-03-28

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