ATE138364T1 - Hemmungsstoff für aldosereduktase - Google Patents

Hemmungsstoff für aldosereduktase

Info

Publication number
ATE138364T1
ATE138364T1 AT91307304T AT91307304T ATE138364T1 AT E138364 T1 ATE138364 T1 AT E138364T1 AT 91307304 T AT91307304 T AT 91307304T AT 91307304 T AT91307304 T AT 91307304T AT E138364 T1 ATE138364 T1 AT E138364T1
Authority
AT
Austria
Prior art keywords
reductase inhibitor
aldose reductase
different
chem
carrier
Prior art date
Application number
AT91307304T
Other languages
English (en)
Inventor
Yukio Suzuki
Kouichi Kuno
Motoshi Shoda
Masao Yaso
Satoshi Yaginuma
Akira Asahi
Original Assignee
Asahi Chemical Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Ind filed Critical Asahi Chemical Ind
Application granted granted Critical
Publication of ATE138364T1 publication Critical patent/ATE138364T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT91307304T 1990-08-08 1991-08-08 Hemmungsstoff für aldosereduktase ATE138364T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2208128A JPH0495025A (ja) 1990-08-08 1990-08-08 アルドースリダクターゼ阻害剤

Publications (1)

Publication Number Publication Date
ATE138364T1 true ATE138364T1 (de) 1996-06-15

Family

ID=16551106

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91307304T ATE138364T1 (de) 1990-08-08 1991-08-08 Hemmungsstoff für aldosereduktase

Country Status (6)

Country Link
US (1) US5155259A (de)
EP (1) EP0473308B1 (de)
JP (1) JPH0495025A (de)
AT (1) ATE138364T1 (de)
DE (1) DE69119668T2 (de)
ES (1) ES2087247T3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5560936A (en) * 1992-10-26 1996-10-01 The United States Of America As Represented By The Department Of Health And Human Services Intrinsic inhibitors of aldose reductase
KR100340273B1 (ko) 1997-10-14 2002-06-14 야마모토 카즈모토 비페닐-5-알칸산 유도체 및 이의 용도
US6867320B2 (en) * 2002-02-21 2005-03-15 Asahi Kasei Pharma Corporation Substituted phenylalkanoic acid derivatives and use thereof
KR20060079190A (ko) * 2003-08-14 2006-07-05 아사히 가세이 파마 가부시키가이샤 치환 아릴알칸산 유도체 및 그의 용도
AU2007274477B2 (en) 2006-07-20 2010-11-25 Asahi Kasei Pharma Corporation Novel crystal of substituted phenylalkanoic acid and production process
EP2848252A3 (de) * 2007-03-23 2015-06-17 The Board of Regents of the University of Texas System Aldose-Reduktase-Inhibitoren zur Behandlung von Uveitis
US8916563B2 (en) 2010-07-16 2014-12-23 The Trustees Of Columbia University In The City Of New York Aldose reductase inhibitors and uses thereof
EP2593456B1 (de) 2010-07-16 2016-11-30 The Trustees of Columbia University in the City of New York Aldosereduktasehemmer und deren verwendungen
EP3352754B1 (de) 2016-06-21 2020-09-02 The Trustees of Columbia University in the City of New York Aldosereduktaseinhibitoren und verfahren zur verwendung davon
IL272246B2 (en) 2017-07-28 2026-01-01 Applied Therapeutics Inc History of 2-(4-oxo/thioketone/azo-3-((substituted)benzo[d]thiazol-2-yl)methyl)- 3,4-dihydrothieno[3,4-d]pyridazin-1-yl)acetic acid for use as an aldose reductase inhibitor for the treatment of galactosemia or prevention of galactosemia-related complications
KR20220003529A (ko) 2019-04-01 2022-01-10 어플라이드 테라퓨틱스 인크. 알도스 리덕타제의 억제제
MX2021013511A (es) 2019-05-07 2022-02-23 Univ Miami Tratamiento y deteccion de neuropatias heredadas y trastornos asociados.
IL297779A (en) 2020-05-01 2022-12-01 Applied Therapeutics Inc Aldose reductase inhibitors for treating sorbitol dehydrogenase deficiency

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62205095A (ja) * 1986-03-04 1987-09-09 Toyo Jozo Co Ltd 新生理活性物質アルドスタチンおよびその製造法

Also Published As

Publication number Publication date
DE69119668T2 (de) 1997-01-02
EP0473308B1 (de) 1996-05-22
JPH0495025A (ja) 1992-03-27
ES2087247T3 (es) 1996-07-16
US5155259A (en) 1992-10-13
DE69119668D1 (de) 1996-06-27
EP0473308A1 (de) 1992-03-04

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties