DK0923378T3 - Fremme af sårheling ved kemisk modificerede tetracykliner - Google Patents
Fremme af sårheling ved kemisk modificerede tetracyklinerInfo
- Publication number
- DK0923378T3 DK0923378T3 DK97935248T DK97935248T DK0923378T3 DK 0923378 T3 DK0923378 T3 DK 0923378T3 DK 97935248 T DK97935248 T DK 97935248T DK 97935248 T DK97935248 T DK 97935248T DK 0923378 T3 DK0923378 T3 DK 0923378T3
- Authority
- DK
- Denmark
- Prior art keywords
- activity
- wound healing
- capacity
- epithelialized tissue
- healing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/691,135 US5827840A (en) | 1996-08-01 | 1996-08-01 | Promotion of wound healing by chemically-modified tetracyclines |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0923378T3 true DK0923378T3 (da) | 2006-04-03 |
Family
ID=24775298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97935248T DK0923378T3 (da) | 1996-08-01 | 1997-08-01 | Fremme af sårheling ved kemisk modificerede tetracykliner |
Country Status (11)
Country | Link |
---|---|
US (1) | US5827840A (fr) |
EP (1) | EP0923378B1 (fr) |
JP (1) | JP2000516214A (fr) |
KR (1) | KR100494206B1 (fr) |
AT (1) | ATE309804T1 (fr) |
AU (1) | AU3823497A (fr) |
CA (1) | CA2261805C (fr) |
DE (1) | DE69734661T2 (fr) |
DK (1) | DK0923378T3 (fr) |
ES (1) | ES2255107T3 (fr) |
WO (1) | WO1998005340A1 (fr) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6015804A (en) * | 1998-09-11 | 2000-01-18 | The Research Foundation Of State University Of New York | Method of using tetracycline compounds to enhance interleukin-10 production |
US7300667B1 (en) | 1999-05-27 | 2007-11-27 | Euro-Celtique, S.A. | Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract |
PT1180017E (pt) | 1999-05-27 | 2010-05-28 | Euro Celtique Sa | Preparações com povidona-iodo para o tratamento de feridas |
EP1829546A1 (fr) * | 1999-09-14 | 2007-09-05 | Mucosal Therapeutics LLC | Formulations pour traiter ou prévenir la mucosite |
JP2003509367A (ja) * | 1999-09-14 | 2003-03-11 | オラファーマ, インコーポレイテッド | 粘膜炎を治療または予防するための処方物 |
US6946118B1 (en) | 1999-09-14 | 2005-09-20 | Orapharma, Inc. | Formulations for treating or preventing mucositis |
NZ522733A (en) * | 2000-06-02 | 2004-05-28 | Yu Liu | Non-antibacterial tetracycline as anti-fungal agents |
KR100982753B1 (ko) * | 2001-04-05 | 2010-09-16 | 콜라제넥스 파마슈티칼스, 인크 | 테트라사이클린 화합물 및 테트라사이클린 유도체의 전달조절 |
US7211267B2 (en) | 2001-04-05 | 2007-05-01 | Collagenex Pharmaceuticals, Inc. | Methods of treating acne |
PT1383508E (pt) * | 2001-04-05 | 2006-11-30 | Collagenex Pharm Inc | Doxiciclina destinada ao tratamento da acne |
EP1408987B1 (fr) | 2001-07-13 | 2013-04-10 | Paratek Pharmaceuticals, Inc. | Composes de tetracycline a activites therapeutiques cibles |
US20060194773A1 (en) * | 2001-07-13 | 2006-08-31 | Paratek Pharmaceuticals, Inc. | Tetracyline compounds having target therapeutic activities |
WO2003094954A1 (fr) * | 2001-09-25 | 2003-11-20 | Quick Med Technologies, Inc. | Composition et procede servant a minimiser ou a eviter les effets nefastes de vesicants |
WO2003053447A1 (fr) * | 2001-12-20 | 2003-07-03 | Hanauske-Abel Hartmut M | Traitement permettant de prevenir ou de retarder un accouchement premature |
EP2311798A1 (fr) | 2002-01-08 | 2011-04-20 | Paratek Pharmaceuticals, Inc. | Composés de tétracycline 4-dedimethylamino |
EA200802365A1 (ru) | 2002-03-08 | 2009-08-28 | Паратек Фармасьютикалс, Инк. | Аминометилзамещенные тетрациклиновые соединения |
IL164180A0 (en) | 2002-03-21 | 2005-12-18 | Paratek Pharm Innc | Substituted tetracycline compounds |
US8192749B2 (en) | 2003-04-16 | 2012-06-05 | Galderma Laboratories Inc. | Methods of simultaneously treating ocular rosacea and acne rosacea |
EP1494681A4 (fr) * | 2002-04-16 | 2008-08-06 | Collagenex Pharm Inc | Procedes pour traiter simultanement de la keratite rosacee et de l'acne rosacee |
WO2003092629A2 (fr) * | 2002-05-06 | 2003-11-13 | Collagenex Pharmaceuticals, Inc. | Procede de traitement simultane de mucosite et d'infection fongique |
EP1531830A4 (fr) * | 2002-07-12 | 2007-09-05 | Univ New York State Res Found | Procede de reduction des taux de proteine c-reactive au moyen de formulations de tetracycline non antibacteriennes |
WO2004006850A2 (fr) | 2002-07-12 | 2004-01-22 | Paratek Pharmaceuticals, Inc | Composes de tetracycline substituee en 3, 10, et 12a |
US20080139512A1 (en) * | 2002-09-25 | 2008-06-12 | Quick-Med Technologies, Inc. | Method for minimizing or avoiding adverse effects of vesicants |
US7749532B2 (en) | 2003-04-07 | 2010-07-06 | Supernus Pharmaceuticals, Inc. | Once daily formulations of tetracyclines |
WO2005009943A2 (fr) | 2003-07-09 | 2005-02-03 | Paratek Pharmaceuticals, Inc. | Composes de tetracycline substitues |
JP4738333B2 (ja) | 2003-07-09 | 2011-08-03 | パラテック ファーマシューティカルズ インコーポレイテッド | 9−アミノメチルテトラサイクリン化合物のプロドラッグ |
NZ547628A (en) * | 2003-11-06 | 2010-07-30 | Univ New York State Res Found | Methods of treating eczema |
CA2553510C (fr) | 2004-01-15 | 2012-09-25 | Paratek Pharmaceuticals, Inc. | Derives a cycle aromatique a provenant de composes de tetracycline |
CA2585418A1 (fr) | 2004-10-25 | 2006-05-04 | Paratek Pharmaceuticals, Inc. | 4-aminotetracyclines et procedes d'utilisation |
EP2949644A3 (fr) | 2004-10-25 | 2016-04-20 | Paratek Pharmaceuticals, Inc. | Composés de tétracycline substituée |
US20060252731A1 (en) * | 2005-05-06 | 2006-11-09 | Pfeiffer David F | Methods of treating recurrent aphthous stomatitis |
CA2616224A1 (fr) * | 2005-07-21 | 2007-02-01 | Paratek Pharmaceuticals, Inc. | Tetracyclines 10-substituees et leurs procedes d'utilisation |
US8318706B2 (en) | 2006-12-21 | 2012-11-27 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds |
PT2120963T (pt) * | 2006-12-21 | 2018-12-17 | Paratek Pharm Innc | Compostos tetraciclina substituídos para tratamento de distúrbios inflamatórios da pele |
CA2688662A1 (fr) | 2007-04-27 | 2008-11-06 | Paratek Pharmaceuticals, Inc. | Methodes de synthese et de purification de composes de type aminoalkyle de tetracycline |
ATE555079T1 (de) * | 2007-07-06 | 2012-05-15 | Paratek Pharm Innc | Verfahren zur synthese von 9-substituiertem minocyclin |
TW202216656A (zh) | 2008-05-23 | 2022-05-01 | 美商Prtk Spv2公司 | 四環素化合物之甲苯磺酸鹽及同素異形體 |
ES2558512T3 (es) | 2008-08-08 | 2016-02-04 | Tetraphase Pharmaceuticals, Inc. | Compuestos de tetraciclina sustituida con C7-fluoro |
CN102459153A (zh) | 2009-05-08 | 2012-05-16 | 四相制药公司 | 四环素类化合物 |
CN105622496B (zh) | 2009-08-28 | 2019-03-05 | 四相制药公司 | 四环素类化合物 |
PL2552890T3 (pl) | 2010-03-31 | 2017-07-31 | Tetraphase Pharmaceuticals, Inc. | Policykliczne związki tetracyklinowe |
PT2890673T (pt) | 2012-08-31 | 2019-02-19 | Tetraphase Pharmaceuticals Inc | Compostos de tetraciclina |
CN104307031B (zh) * | 2014-11-10 | 2015-12-30 | 刘维峰 | 一种皮肤外用修复材料的制备方法及用途 |
US10961190B2 (en) | 2016-10-19 | 2021-03-30 | Tetraphase Pharmaceuticals, Inc. | Crystalline forms of eravacycline |
WO2020097450A1 (fr) | 2018-11-09 | 2020-05-14 | Tetraphase Pharmaceuticals, Inc. | Formes polymorphes d'un composé et utilisations associées |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1767900U (de) * | 1958-03-27 | 1958-06-04 | Herbert Dipl Ing Fritzsche | Hand- oder taschenleuchte mit blinker. |
US3823212A (en) * | 1968-11-27 | 1974-07-09 | Freudenberg C Fa | Process for the production of collagen fiber fabrics in the form of felt-like membranes or sponge-like layers |
US4016877A (en) * | 1976-02-23 | 1977-04-12 | Avicon, Inc. | Fibrous collagen derived web having hemostatic and wound sealing properties |
US4294241A (en) * | 1977-06-09 | 1981-10-13 | Teruo Miyata | Collagen skin dressing |
US4130555A (en) * | 1977-09-06 | 1978-12-19 | Nippi Incorporated | Peptide mixtures derived from collagenous material or gelatin |
US4412947A (en) * | 1979-09-12 | 1983-11-01 | Seton Company | Collagen sponge |
US4440680A (en) * | 1980-09-24 | 1984-04-03 | Seton Company | Macromolecular biologically active collagen articles |
DE3037513C2 (de) * | 1980-10-03 | 1983-05-05 | Steffan, Wolfgang, 8425 Neustadt | Kollagene Wundauflage |
US4578067A (en) * | 1982-04-12 | 1986-03-25 | Alcon (Puerto Rico) Inc. | Hemostatic-adhesive, collagen dressing for severed biological surfaces |
US4925833A (en) * | 1983-12-29 | 1990-05-15 | The Research Foundation Of State University Of New York | Use of tetracycline to enhance bone protein synthesis and/or treatment of osteoporosis |
US4666897A (en) * | 1983-12-29 | 1987-05-19 | Research Foundation Of State University | Inhibition of mammalian collagenolytic enzymes by tetracyclines |
US4704383A (en) * | 1983-12-29 | 1987-11-03 | The Research Foundation Of State University Of New York | Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same |
US4935412A (en) * | 1983-12-29 | 1990-06-19 | The Research Foundation Of State University Of New York | Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same |
US4837024A (en) * | 1984-02-24 | 1989-06-06 | The Regents Of The University Of California | Compositions, articles and mehtod for improving wound healing |
US4837285A (en) * | 1984-03-27 | 1989-06-06 | Medimatrix | Collagen matrix beads for soft tissue repair |
IT1181737B (it) * | 1985-11-26 | 1987-09-30 | Pierfrancesco Morganti | Supproto di collagene biologicamente attivo per uso cosmetico e farmaceutico e metodo per prepararlo |
US5196196A (en) * | 1986-06-03 | 1993-03-23 | Incyte Pharmaceuticals, Inc. | Use of protease nexin-I in wound dressings |
US4813942A (en) * | 1987-03-17 | 1989-03-21 | Bioderm, Inc. | Three step wound treatment method and dressing therefor |
US4969912A (en) * | 1988-02-18 | 1990-11-13 | Kelman Charles D | Human collagen processing and autoimplant use |
US5110604A (en) * | 1988-06-30 | 1992-05-05 | Collagen Corporation | Processes for producing collagen matrixes and methods of using same |
US4950483A (en) * | 1988-06-30 | 1990-08-21 | Collagen Corporation | Collagen wound healing matrices and process for their production |
US5024841A (en) * | 1988-06-30 | 1991-06-18 | Collagen Corporation | Collagen wound healing matrices and process for their production |
GB8827305D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
US5227168A (en) * | 1989-11-21 | 1993-07-13 | Bruce Barber | Method of treating a wound |
US5308839A (en) * | 1989-12-04 | 1994-05-03 | The Research Foundation Of State University Of New York | Composition comprising non-steroidal anti-inflammatory agent tenidap and effectively non-antibacterial tetracycline |
JP3016587B2 (ja) * | 1989-12-04 | 2000-03-06 | ザ・リサーチ・ファンデーション・オブ・ステート・ユニバーシティ・オブ・ニューヨーク | 非ステロイド抗炎症剤及びテトラサイクリンの配合 |
GB9000846D0 (en) * | 1990-01-15 | 1990-03-14 | Beecham Group Plc | Novel compounds |
US5008283A (en) * | 1990-03-19 | 1991-04-16 | Pfizer Inc. | Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase |
GB9008065D0 (en) * | 1990-04-10 | 1990-06-06 | Beecham Group Plc | Novel compounds |
US5081106A (en) * | 1990-07-16 | 1992-01-14 | The Oregon Health Sciences University | Wound dressing protocol utilizing collagen gelatin formed with iodine |
US5156601A (en) * | 1991-03-20 | 1992-10-20 | Hydromer, Inc. | Tacky, hydrophilic gel dressings and products therefrom |
US5229380A (en) * | 1991-06-28 | 1993-07-20 | Harris Richard Y | Method for treating helicobacter pylori gastritis |
US5258371A (en) * | 1992-05-29 | 1993-11-02 | Kuraray Co., Ltd. | Method to reduce connective tissue destruction |
EP0599397B1 (fr) * | 1992-11-17 | 1996-08-28 | The Research Foundation Of State University Of New York | Tétracyclines comprenant les tétracyclines modifiées chimiquement afin d'être non-antimicrobiennes inhibent la réticulation excessive du collagène lors du diabète |
-
1996
- 1996-08-01 US US08/691,135 patent/US5827840A/en not_active Expired - Lifetime
-
1997
- 1997-08-01 CA CA002261805A patent/CA2261805C/fr not_active Expired - Fee Related
- 1997-08-01 DE DE69734661T patent/DE69734661T2/de not_active Expired - Lifetime
- 1997-08-01 AU AU38234/97A patent/AU3823497A/en not_active Abandoned
- 1997-08-01 JP JP10508075A patent/JP2000516214A/ja active Pending
- 1997-08-01 AT AT97935248T patent/ATE309804T1/de active
- 1997-08-01 DK DK97935248T patent/DK0923378T3/da active
- 1997-08-01 EP EP97935248A patent/EP0923378B1/fr not_active Expired - Lifetime
- 1997-08-01 KR KR10-1999-7000866A patent/KR100494206B1/ko not_active IP Right Cessation
- 1997-08-01 WO PCT/US1997/013534 patent/WO1998005340A1/fr active IP Right Grant
- 1997-08-01 ES ES97935248T patent/ES2255107T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69734661T2 (de) | 2006-08-10 |
KR100494206B1 (ko) | 2005-06-13 |
AU3823497A (en) | 1998-02-25 |
DE69734661D1 (de) | 2005-12-22 |
EP0923378A4 (fr) | 2000-11-15 |
CA2261805A1 (fr) | 1998-02-12 |
US5827840A (en) | 1998-10-27 |
WO1998005340A1 (fr) | 1998-02-12 |
ATE309804T1 (de) | 2005-12-15 |
CA2261805C (fr) | 2008-11-04 |
KR20000029753A (ko) | 2000-05-25 |
EP0923378B1 (fr) | 2005-11-16 |
ES2255107T3 (es) | 2006-06-16 |
EP0923378A1 (fr) | 1999-06-23 |
JP2000516214A (ja) | 2000-12-05 |
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