ATE196604T1 - Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und - regenerierung - Google Patents
Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und - regenerierungInfo
- Publication number
- ATE196604T1 ATE196604T1 AT92908042T AT92908042T ATE196604T1 AT E196604 T1 ATE196604 T1 AT E196604T1 AT 92908042 T AT92908042 T AT 92908042T AT 92908042 T AT92908042 T AT 92908042T AT E196604 T1 ATE196604 T1 AT E196604T1
- Authority
- AT
- Austria
- Prior art keywords
- regeneration
- dexamethason
- composition containing
- tissue repair
- pdgf
- Prior art date
Links
- 230000017423 tissue regeneration Effects 0.000 title abstract 3
- 238000011069 regeneration method Methods 0.000 title abstract 2
- 230000001737 promoting effect Effects 0.000 title 1
- 102000010780 Platelet-Derived Growth Factor Human genes 0.000 abstract 3
- 108010038512 Platelet-Derived Growth Factor Proteins 0.000 abstract 3
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000028169 periodontal disease Diseases 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000029663 wound healing Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/669,070 US5149691A (en) | 1991-03-12 | 1991-03-12 | Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone |
| PCT/US1992/002043 WO1992016181A2 (en) | 1991-03-12 | 1992-03-12 | Composition for promoting tissue repair and regeneration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE196604T1 true ATE196604T1 (de) | 2000-10-15 |
Family
ID=24684879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92908042T ATE196604T1 (de) | 1991-03-12 | 1992-03-12 | Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und - regenerierung |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5149691A (de) |
| EP (1) | EP0575484B1 (de) |
| JP (1) | JPH07505858A (de) |
| AT (1) | ATE196604T1 (de) |
| AU (1) | AU656372B2 (de) |
| CA (1) | CA2106073C (de) |
| DE (1) | DE69231486T2 (de) |
| WO (1) | WO1992016181A2 (de) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5149691A (en) * | 1991-03-12 | 1992-09-22 | Creative Biomolecules, Inc. | Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone |
| US5837258A (en) * | 1991-08-30 | 1998-11-17 | University Of South Florida | Induction of tissue, bone or cartilage formation using connective tissue growth factor |
| US5770209A (en) * | 1991-08-30 | 1998-06-23 | University Of South Florida | Acceleration of wound healing using connective tissue growth factor |
| US7384634B2 (en) * | 1991-08-30 | 2008-06-10 | University Of South Florida | Connective tissue growth factor |
| US5408040A (en) * | 1991-08-30 | 1995-04-18 | University Of South Florida | Connective tissue growth factor(CTGF) |
| US5326695A (en) * | 1992-05-15 | 1994-07-05 | Ludwig Institute For Cancer Research | Platelet derived growth factor agonists |
| US5444151A (en) * | 1992-05-15 | 1995-08-22 | Ludwig Institute For Cancer Research | Platelet derived growth factor antagonists |
| DE4228457A1 (de) * | 1992-08-27 | 1994-04-28 | Beiersdorf Ag | Herstellung von heterodimerem PDGF-AB mit Hilfe eines bicistronischen Vektorsystems in Säugerzellen |
| ATE180674T1 (de) * | 1993-03-29 | 1999-06-15 | Zymogenetics Inc | Osteoblastswachstumfordernde zusammensetzungen die pdgf und vitamin-d enthalten |
| US5455041A (en) * | 1993-09-13 | 1995-10-03 | Research Foundation Of State University Of New York At Buffalo | Method for inducing periodontal tissue regeneration |
| US5942496A (en) * | 1994-02-18 | 1999-08-24 | The Regent Of The University Of Michigan | Methods and compositions for multiple gene transfer into bone cells |
| US6551618B2 (en) | 1994-03-15 | 2003-04-22 | University Of Birmingham | Compositions and methods for delivery of agents for neuronal regeneration and survival |
| EP0743066A3 (de) * | 1995-05-16 | 1998-09-30 | Mitsui Pharmaceuticals, Inc. | Wundheilmittel |
| US5776193A (en) * | 1995-10-16 | 1998-07-07 | Orquest, Inc. | Bone grafting matrix |
| US6902584B2 (en) | 1995-10-16 | 2005-06-07 | Depuy Spine, Inc. | Bone grafting matrix |
| EP0915967A1 (de) * | 1996-05-28 | 1999-05-19 | The Board Of Regents Of The University Of Michigan | Entwicklung von oralem gewebe |
| DE19754140A1 (de) * | 1997-12-05 | 1999-06-24 | Era Beschichtung Gmbh & Co Kg | Innenraummaterial auf der Basis von Kunststoff, Verfahren zu dessen Herstellung und Verwendung desselben |
| MXPA00000009A (es) | 1998-06-22 | 2005-09-08 | Autologous Wound Therapy Inc | Solicitud para patente de utilidad para curativo de heridas mejorado enriquecido con plaquetas. |
| WO2001032197A2 (en) * | 1999-11-02 | 2001-05-10 | Eli Lilly And Company | Methods of using lp8, a pdgf-related protein, to treat musculoskeletal disorders |
| EP1390380B1 (de) | 2001-03-05 | 2009-09-30 | Siemens Healthcare Diagnostics Inc. | Verfahren und primer zur analyse von hiv-1-mutationen |
| AU2002312416A1 (en) * | 2001-06-07 | 2003-12-22 | Chiou Consulting, Inc | Compositions and methods for the prophylaxis and treatment of aphthous ulcers and herpes simplex lesions |
| US7819888B2 (en) * | 2001-10-23 | 2010-10-26 | Innovasive Devices, Inc. | Method and apparatus for harvesting and implanting bone plugs |
| DE10152956A1 (de) * | 2001-10-26 | 2003-05-15 | Fresenius Kabi De Gmbh | Pharmazeutische Zusammensetzung, einen Wachstumsfaktor und/oder ein Zytokin und ein antiseptisches Biguanid umfassend |
| US20050142208A1 (en) * | 2002-05-09 | 2005-06-30 | Won Min Yoo | Pharmceutical composition for treatment of wounds conntaining blood plasma or serum |
| US20040018220A1 (en) * | 2002-07-26 | 2004-01-29 | Chiou Consulting, Inc. | Aqueous compositions for facial cosmetics |
| US6616923B1 (en) * | 2002-07-26 | 2003-09-09 | Chiou Consulting, Inc. | Aqueous compositions for facial cosmetics |
| ATE510605T1 (de) | 2003-03-14 | 2011-06-15 | Univ Columbia | Systeme und verfahren für auf blut basierende therapien mit einer membranlosen mikrofluid- austauschvorrichtung |
| US20060076295A1 (en) | 2004-03-15 | 2006-04-13 | The Trustees Of Columbia University In The City Of New York | Systems and methods of blood-based therapies having a microfluidic membraneless exchange device |
| US7309232B2 (en) * | 2003-10-10 | 2007-12-18 | Dentigenix Inc. | Methods for treating dental conditions using tissue scaffolds |
| US7258875B2 (en) * | 2003-12-04 | 2007-08-21 | Chiou Consulting, Inc. | Compositions and methods for topical treatment of skin infection |
| US8293890B2 (en) * | 2004-04-30 | 2012-10-23 | Advanced Cardiovascular Systems, Inc. | Hyaluronic acid based copolymers |
| GB0414803D0 (en) * | 2004-07-01 | 2004-08-04 | Glaxo Group Ltd | Composition |
| US7473678B2 (en) * | 2004-10-14 | 2009-01-06 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods of use thereof |
| US20060115266A1 (en) * | 2004-12-01 | 2006-06-01 | Gil Levi | All-optical protection signaling systems and methods in optical communication networks |
| US8119591B2 (en) * | 2005-08-01 | 2012-02-21 | Genera Istrazivanja D.O.O. | Methods and compositions for regenerating articular cartilage |
| BRPI0618794A2 (pt) | 2005-11-17 | 2011-09-13 | Biomimetic Therapeutics Inc | uso de uma matriz biocompatìvel, kit e composição para aumento ósseo, especialmente para aumento do osso maxilofacial |
| CA2640064A1 (en) | 2006-01-23 | 2007-07-26 | Imagene Co., Ltd. | Novel peptide and use thereof |
| EP2311505B1 (de) * | 2006-02-09 | 2013-11-06 | BioMimetic Therapeutics, LLC | Zusammensetzungen und Verfahren zur Behandlung von Knochen |
| EP2019658B1 (de) | 2006-05-22 | 2012-01-25 | The Trustees of Columbia University in the City of New York | Verfahren für membranlosen mikrofluidaustausch in einem h-filter und filterung der extraktionsflüssigkeitsausgangsströme |
| ES2664229T3 (es) | 2006-06-30 | 2018-04-18 | Biomimetic Therapeutics, Llc | Composiciones y métodos de biomatriz-PDGF para el tratamiento de lesiones del manguito rotador |
| US9161967B2 (en) | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
| WO2008073628A2 (en) * | 2006-11-03 | 2008-06-19 | Biomimetic Therapeutics, Inc. | Compositions and methods for arthrodetic procedures |
| AU2013203287B2 (en) * | 2006-11-03 | 2015-12-17 | Stryker Corporation | Compositions and methods for arthrodetic procedures |
| US9511076B2 (en) * | 2008-05-30 | 2016-12-06 | Clarion Research Group | Formulations and methods for recovery from dental surgery |
| WO2009052221A2 (en) * | 2007-10-15 | 2009-04-23 | The Regents Of The University Of Colorado | Methods for extracting platelets and compositions obtained therefrom |
| CA2710822C (en) | 2008-01-07 | 2022-06-14 | Johannes Gerhardus Maria Bolscher | Use of histatin derived peptides for promoting wound healing |
| US8496606B2 (en) | 2008-02-04 | 2013-07-30 | The Trustees Of Columbia University In The City Of New York | Fluid separation devices, systems and methods |
| ES2422259T3 (es) | 2008-02-07 | 2013-09-10 | Biomimetic Therapeutics Inc | Composiciones para la osteogénesis por distracción |
| MX2011002555A (es) | 2008-09-09 | 2011-08-03 | Biomimetic Therapeutics Inc | Composiciones de factor de crecimiento derivadas de plaquetas y metodo para el tratamiento de lesiones de tendon y ligamentos. |
| WO2010100282A1 (en) * | 2009-03-06 | 2010-09-10 | Universite Paris Descartes | Method for treating cancer |
| CN107080834A (zh) | 2010-02-22 | 2017-08-22 | 生物模拟治疗有限责任公司 | 用于治疗腱病的血小板衍生生长因子组合物和方法 |
| JP2013536158A (ja) | 2010-06-14 | 2013-09-19 | ジーン シグナル インターナショナル ソシエテ アノニム | 創傷治癒のための新規ペプチド |
| US8288334B2 (en) | 2010-06-14 | 2012-10-16 | Gene Signal International Sa | Peptides for wound healing |
| ES2410804T3 (es) | 2010-06-14 | 2013-07-03 | Gene Signal International Sa | Péptidos para la curación de heridas |
| US20130202576A1 (en) | 2010-07-12 | 2013-08-08 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases |
| WO2013062995A1 (en) * | 2011-10-25 | 2013-05-02 | Biomimetic Therapeutics, Inc. | Compositions and methods for treating deep partial and full thickness wounds and injuries |
| CN104334196B (zh) | 2012-02-16 | 2018-04-10 | Atyr 医药公司 | 用于治疗自身免疫疾病和炎性疾病的组氨酰‑tRNA合成酶 |
| AU2014233436B2 (en) | 2013-03-15 | 2019-12-05 | Atyr Pharma, Inc. | Histidyl-tRNA synthetase-Fc conjugates |
| CN107106492B (zh) | 2014-10-14 | 2022-07-05 | 塞缪尔·林奇 | 用于治疗伤口的组合物 |
| JP7679175B2 (ja) | 2017-04-20 | 2025-05-19 | エータイアー ファーマ, インコーポレイテッド | 肺の炎症を治療するための組成物および方法 |
| KR102668789B1 (ko) | 2018-11-23 | 2024-05-24 | (주)메디코스바이오텍 | 창상치료용 약학조성물 |
| CZ308845B6 (cs) | 2019-01-21 | 2021-07-07 | Globetech Innovation S.R.O | Farmaceutická směs topicky hojivých peptidových složek pro použití k topické léčbě kožních defektů a/nebo k topickému hojení ran |
| PL245202B1 (pl) | 2020-03-06 | 2024-06-03 | Gdanski Univ Medyczny | Lipopeptydowe koniugaty i ich sole, sposób wytwarzania lipopeptydowych koniugatów i ich soli, kompozycja farmaceutyczna zawierająca lipopeptydowy koniugat i jego sole do leczenia ran przewlekłych |
| LU505892B1 (fr) | 2023-12-21 | 2025-06-24 | Lumatrix | Formule pharmaceutique de cicatrisation et de régénération de la peau et son utilisation |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6028999A (ja) * | 1983-06-30 | 1985-02-14 | Maruho Kk | 細胞増殖促進作用を有するたんぱく質、その組成物と製造方法 |
| US4957742A (en) * | 1984-11-29 | 1990-09-18 | Regents Of The University Of Minnesota | Method for promoting hair growth |
| US5124316A (en) * | 1986-11-14 | 1992-06-23 | President And Fellows Of Harvard College | Method for periodontal regeneration |
| US4861757A (en) * | 1986-11-14 | 1989-08-29 | Institute Of Molecular Biology | Wound healing and bone regeneration using PDGF and IGF-I |
| ATE80307T1 (de) * | 1986-12-11 | 1992-09-15 | British Tech Group | Verbesserungen im gebrauch oder in bezug auf den gebrauch von egf. |
| US4808402A (en) * | 1987-05-29 | 1989-02-28 | Northwestern University | Method and compositions for modulating neovascularization |
| US4874746A (en) * | 1987-12-22 | 1989-10-17 | Institute Of Molecular Biology, Inc. | Wound headling composition of TGF-alpha and PDGF |
| AU657472B2 (en) * | 1990-03-06 | 1995-03-16 | Claude Paul Genero | Towel or blanket support device |
| US5149691A (en) * | 1991-03-12 | 1992-09-22 | Creative Biomolecules, Inc. | Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone |
| EP0584286B1 (de) * | 1991-04-12 | 1998-08-05 | Creative Biomolecules, Inc. | Verwendung von aus blutplättchen gewonnenem wachstumsfaktor zur herstellung eines medikaments zur behandlung von gastrointestinaler geschwüre |
-
1991
- 1991-03-12 US US07/669,070 patent/US5149691A/en not_active Expired - Fee Related
-
1992
- 1992-03-12 WO PCT/US1992/002043 patent/WO1992016181A2/en not_active Ceased
- 1992-03-12 EP EP92908042A patent/EP0575484B1/de not_active Expired - Lifetime
- 1992-03-12 JP JP4507585A patent/JPH07505858A/ja active Pending
- 1992-03-12 US US07/849,931 patent/US5376636A/en not_active Expired - Fee Related
- 1992-03-12 AU AU15591/92A patent/AU656372B2/en not_active Ceased
- 1992-03-12 DE DE69231486T patent/DE69231486T2/de not_active Expired - Fee Related
- 1992-03-12 CA CA002106073A patent/CA2106073C/en not_active Expired - Fee Related
- 1992-03-12 AT AT92908042T patent/ATE196604T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US5149691A (en) | 1992-09-22 |
| DE69231486D1 (de) | 2000-11-02 |
| WO1992016181A3 (en) | 1992-11-12 |
| EP0575484B1 (de) | 2000-09-27 |
| US5376636A (en) | 1994-12-27 |
| CA2106073A1 (en) | 1993-09-13 |
| AU1559192A (en) | 1992-10-21 |
| AU656372B2 (en) | 1995-02-02 |
| EP0575484A1 (de) | 1993-12-29 |
| WO1992016181A2 (en) | 1992-10-01 |
| DE69231486T2 (de) | 2001-04-26 |
| JPH07505858A (ja) | 1995-06-29 |
| CA2106073C (en) | 2003-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |