DE69231486D1 - Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und -regenerierung - Google Patents

Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und -regenerierung

Info

Publication number
DE69231486D1
DE69231486D1 DE69231486T DE69231486T DE69231486D1 DE 69231486 D1 DE69231486 D1 DE 69231486D1 DE 69231486 T DE69231486 T DE 69231486T DE 69231486 T DE69231486 T DE 69231486T DE 69231486 D1 DE69231486 D1 DE 69231486D1
Authority
DE
Germany
Prior art keywords
regeneration
dexamethasone
composition containing
tissue repair
pdgf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69231486T
Other languages
English (en)
Other versions
DE69231486T2 (de
Inventor
Robert Bruce Rutherford
Marc F Charette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Connecticut
Creative Biomolecules Inc
Original Assignee
University of Connecticut
Creative Biomolecules Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Connecticut, Creative Biomolecules Inc filed Critical University of Connecticut
Application granted granted Critical
Publication of DE69231486D1 publication Critical patent/DE69231486D1/de
Publication of DE69231486T2 publication Critical patent/DE69231486T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69231486T 1991-03-12 1992-03-12 Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und -regenerierung Expired - Fee Related DE69231486T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/669,070 US5149691A (en) 1991-03-12 1991-03-12 Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone
PCT/US1992/002043 WO1992016181A2 (en) 1991-03-12 1992-03-12 Composition for promoting tissue repair and regeneration

Publications (2)

Publication Number Publication Date
DE69231486D1 true DE69231486D1 (de) 2000-11-02
DE69231486T2 DE69231486T2 (de) 2001-04-26

Family

ID=24684879

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69231486T Expired - Fee Related DE69231486T2 (de) 1991-03-12 1992-03-12 Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und -regenerierung

Country Status (8)

Country Link
US (2) US5149691A (de)
EP (1) EP0575484B1 (de)
JP (1) JPH07505858A (de)
AT (1) ATE196604T1 (de)
AU (1) AU656372B2 (de)
CA (1) CA2106073C (de)
DE (1) DE69231486T2 (de)
WO (1) WO1992016181A2 (de)

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US5770209A (en) * 1991-08-30 1998-06-23 University Of South Florida Acceleration of wound healing using connective tissue growth factor
US5408040A (en) * 1991-08-30 1995-04-18 University Of South Florida Connective tissue growth factor(CTGF)
US5444151A (en) * 1992-05-15 1995-08-22 Ludwig Institute For Cancer Research Platelet derived growth factor antagonists
US5326695A (en) * 1992-05-15 1994-07-05 Ludwig Institute For Cancer Research Platelet derived growth factor agonists
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US5455041A (en) * 1993-09-13 1995-10-03 Research Foundation Of State University Of New York At Buffalo Method for inducing periodontal tissue regeneration
US5942496A (en) * 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
EP0743066A3 (de) * 1995-05-16 1998-09-30 Mitsui Pharmaceuticals, Inc. Wundheilmittel
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US6902584B2 (en) 1995-10-16 2005-06-07 Depuy Spine, Inc. Bone grafting matrix
EP0915967A1 (de) * 1996-05-28 1999-05-19 The Board Of Regents Of The University Of Michigan Entwicklung von oralem gewebe
DE19754140A1 (de) * 1997-12-05 1999-06-24 Era Beschichtung Gmbh & Co Kg Innenraummaterial auf der Basis von Kunststoff, Verfahren zu dessen Herstellung und Verwendung desselben
AU2763099A (en) 1998-06-22 2000-01-10 Charles E. Worden Enriched platelet wound healant
WO2001032197A2 (en) * 1999-11-02 2001-05-10 Eli Lilly And Company Methods of using lp8, a pdgf-related protein, to treat musculoskeletal disorders
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RU2308954C2 (ru) 2002-05-09 2007-10-27 Медиджинез Фармацевтическая композиция для лечения ран, содержащая плазму или сыворотку крови
US6616923B1 (en) * 2002-07-26 2003-09-09 Chiou Consulting, Inc. Aqueous compositions for facial cosmetics
US20040018220A1 (en) * 2002-07-26 2004-01-29 Chiou Consulting, Inc. Aqueous compositions for facial cosmetics
US20060076295A1 (en) 2004-03-15 2006-04-13 The Trustees Of Columbia University In The City Of New York Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
EP1622691B1 (de) 2003-03-14 2011-05-25 The Trustees of Columbia University in the City of New York Systeme und verfahren für auf blut basierende therapien mit einer membranlosen mikrofluid-austauschvorrichtung
US7309232B2 (en) * 2003-10-10 2007-12-18 Dentigenix Inc. Methods for treating dental conditions using tissue scaffolds
US7258875B2 (en) * 2003-12-04 2007-08-21 Chiou Consulting, Inc. Compositions and methods for topical treatment of skin infection
US8293890B2 (en) * 2004-04-30 2012-10-23 Advanced Cardiovascular Systems, Inc. Hyaluronic acid based copolymers
GB0414803D0 (en) * 2004-07-01 2004-08-04 Glaxo Group Ltd Composition
US7473678B2 (en) * 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US20060115266A1 (en) * 2004-12-01 2006-06-01 Gil Levi All-optical protection signaling systems and methods in optical communication networks
US8119591B2 (en) * 2005-08-01 2012-02-21 Genera Istrazivanja D.O.O. Methods and compositions for regenerating articular cartilage
BRPI0618794A2 (pt) 2005-11-17 2011-09-13 Biomimetic Therapeutics Inc uso de uma matriz biocompatìvel, kit e composição para aumento ósseo, especialmente para aumento do osso maxilofacial
AU2006335748A1 (en) 2006-01-23 2007-07-26 Imagene Co., Ltd. Novel peptide and use thereof
ES2427993T3 (es) * 2006-02-09 2013-11-05 Biomimetic Therapeutics, Llc Composiciones y métodos para el tratamiento de hueso
CN101534917A (zh) 2006-05-22 2009-09-16 纽约市哥伦比亚大学理事会 采用萃取流体排出流过滤的微流无膜交换系统和方法
WO2008005427A2 (en) 2006-06-30 2008-01-10 Biomimetic Therapeutics, Inc. Pdgf-biomatrix compositions and methods for treating rotator cuff injuries
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
AU2007333425B2 (en) 2006-11-03 2014-03-27 Biomimetic Therapeutics, Llc Compositions and methods for arthrodetic procedures
AU2013203287B2 (en) * 2006-11-03 2015-12-17 Biomimetic Therapeutics, Llc. Compositions and methods for arthrodetic procedures
US9511076B2 (en) * 2008-05-30 2016-12-06 Clarion Research Group Formulations and methods for recovery from dental surgery
US8282963B2 (en) * 2007-10-15 2012-10-09 The Regents Of The University Of Colorado, A Body Corporate Methods for extracting platelets and compositions obtained therefrom
DK2244724T3 (en) 2008-01-07 2015-06-29 Rapid Pathogen Screening Inc Use of peptides for promoting wound healing
CN102065926A (zh) 2008-02-04 2011-05-18 纽约市哥伦比亚大学理事会 流体分离装置、系统和方法
RU2010137106A (ru) 2008-02-07 2012-03-20 Байомайметик Терапьютикс, Инк. (Us) Композиции и способы для дистракциионного остеогенеза
CA2735885C (en) 2008-09-09 2018-08-28 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
EP2403508B1 (de) * 2009-03-06 2015-10-28 Université Paris Descartes Verfahren zur krebsbehandlung mit konditioniertem kulturmedium aus zahnfleisch-fibroblasten
BR112012020566B1 (pt) 2010-02-22 2021-09-21 Biomimetic Therapeutics, Llc Composição de fator de crescimento derivado de plaqueta
EP2395015B1 (de) 2010-06-14 2013-03-06 Gene Signal International SA Peptide für die Wundheilung
US8288334B2 (en) 2010-06-14 2012-10-16 Gene Signal International Sa Peptides for wound healing
CN103097405B (zh) 2010-06-14 2015-06-10 基因信号国际公司 用于伤口愈合的新型肽
WO2012021249A2 (en) 2010-07-12 2012-02-16 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases
US20130108683A1 (en) * 2011-10-25 2013-05-02 Biomimetic Therapeutics, Inc. Compositions and methods for treating partial and full thickness wounds and injuries
WO2013123432A2 (en) 2012-02-16 2013-08-22 Atyr Pharma, Inc. Histidyl-trna synthetases for treating autoimmune and inflammatory diseases
CN105378075B (zh) 2013-03-15 2022-04-05 Atyr 医药公司 组氨酰-trna合成酶-fc缀合物
AU2015332556B2 (en) 2014-10-14 2021-04-29 Samuel Lynch Compositions for treating wounds
JP2020517638A (ja) 2017-04-20 2020-06-18 エータイアー ファーマ， インコーポレイテッド 肺の炎症を治療するための組成物および方法
KR102668789B1 (ko) 2018-11-23 2024-05-24 (주)메디코스바이오텍 창상치료용 약학조성물
CZ308845B6 (cs) 2019-01-21 2021-07-07 Globetech Innovation S.R.O Farmaceutická směs topicky hojivých peptidových složek pro použití k topické léčbě kožních defektů a/nebo k topickému hojení ran
PL245202B1 (pl) 2020-03-06 2024-06-03 Gdanski Univ Medyczny Lipopeptydowe koniugaty i ich sole, sposób wytwarzania lipopeptydowych koniugatów i ich soli, kompozycja farmaceutyczna zawierająca lipopeptydowy koniugat i jego sole do leczenia ran przewlekłych

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US4957742A (en) * 1984-11-29 1990-09-18 Regents Of The University Of Minnesota Method for promoting hair growth
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DE69226525T2 (de) * 1991-04-12 1999-04-08 Creative Biomolecules Inc Verwendung von aus blutplättchen gewonnenem wachstumsfaktor zur herstellung eines medikaments zur behandlung von gastrointestinaler geschwüre

Also Published As

Publication number Publication date
AU1559192A (en) 1992-10-21
DE69231486T2 (de) 2001-04-26
CA2106073A1 (en) 1993-09-13
EP0575484A1 (de) 1993-12-29
WO1992016181A2 (en) 1992-10-01
EP0575484B1 (de) 2000-09-27
JPH07505858A (ja) 1995-06-29
AU656372B2 (en) 1995-02-02
WO1992016181A3 (en) 1992-11-12
ATE196604T1 (de) 2000-10-15
CA2106073C (en) 2003-09-30
US5149691A (en) 1992-09-22
US5376636A (en) 1994-12-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee