DK0892815T3 - Fremgangsmåde til fremstilling af en porøs tværbundet polysaccharidgel og dennes anvendelse som gelfiltreringsmedium og ved chromatografi - Google Patents

Fremgangsmåde til fremstilling af en porøs tværbundet polysaccharidgel og dennes anvendelse som gelfiltreringsmedium og ved chromatografi

Info

Publication number
DK0892815T3
DK0892815T3 DK97919836T DK97919836T DK0892815T3 DK 0892815 T3 DK0892815 T3 DK 0892815T3 DK 97919836 T DK97919836 T DK 97919836T DK 97919836 T DK97919836 T DK 97919836T DK 0892815 T3 DK0892815 T3 DK 0892815T3
Authority
DK
Denmark
Prior art keywords
gel
cross
polysaccharide
chromatography
preparation
Prior art date
Application number
DK97919836T
Other languages
Danish (da)
English (en)
Inventor
Hans Berg
Original Assignee
Amersham Biosciences Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Biosciences Ab filed Critical Amersham Biosciences Ab
Application granted granted Critical
Publication of DK0892815T3 publication Critical patent/DK0892815T3/da

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/291—Gel sorbents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/262—Synthetic macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by polycondensation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B01J20/267—Cross-linked polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0036—Galactans; Derivatives thereof
    • C08B37/0039—Agar; Agarose, i.e. D-galactose, 3,6-anhydro-D-galactose, methylated, sulfated, e.g. from the red algae Gelidium and Gracilaria; Agaropectin; Derivatives thereof, e.g. Sepharose, i.e. crosslinked agarose
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B01D15/327—Reversed phase with hydrophobic interaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34—Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3828—Ligand exchange chromatography, e.g. complexation, chelation or metal interaction chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DK97919836T 1996-04-11 1997-04-07 Fremgangsmåde til fremstilling af en porøs tværbundet polysaccharidgel og dennes anvendelse som gelfiltreringsmedium og ved chromatografi DK0892815T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9601368A SE9601368D0 (sv) 1996-04-11 1996-04-11 Process for the production of a porous cross-linked polysaccharide gel

Publications (1)

Publication Number Publication Date
DK0892815T3 true DK0892815T3 (da) 2004-06-21

Family

ID=20402148

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97919836T DK0892815T3 (da) 1996-04-11 1997-04-07 Fremgangsmåde til fremstilling af en porøs tværbundet polysaccharidgel og dennes anvendelse som gelfiltreringsmedium og ved chromatografi

Country Status (10)

Country Link
US (1) US6602990B1 (enExample)
EP (1) EP0892815B1 (enExample)
JP (1) JP4081143B2 (enExample)
AT (1) ATE261992T1 (enExample)
AU (1) AU726086B2 (enExample)
DE (1) DE69728141T2 (enExample)
DK (1) DK0892815T3 (enExample)
ES (1) ES2217413T3 (enExample)
SE (1) SE9601368D0 (enExample)
WO (1) WO1997038018A1 (enExample)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998606A (en) * 1997-11-10 1999-12-07 Grandics; Peter Mn(IV)-mediated crosslinking and functionalization of chromatography media
DE19803415A1 (de) * 1998-01-29 1999-08-05 Aventis Res & Tech Gmbh & Co Trennung von Stoffgemischen unter Einsatz von Polysacchariden
SE9901825D0 (sv) 1999-05-20 1999-05-20 Amersham Pharm Biotech Ab Foamed material filled with inner material
SE0004929D0 (sv) * 2000-12-29 2000-12-29 Apbiotech Ab A method for producing liquid chromatography matrices
SE0004928D0 (sv) 2000-12-29 2000-12-29 Apbiotech Ab A method for the manufacturing of porous material
EP1637864B1 (en) * 2003-03-26 2011-12-21 Daicel Chemical Industries, Ltd. Process for producing a separating agent for chromatography
SE0400490D0 (sv) 2004-02-26 2004-02-26 Amersham Biosciences Ab Plasmid purification
EP1793926B1 (en) * 2004-09-22 2016-11-23 GE Healthcare BioProcess R&D AB Method of preparing a chromatography matrix
SE0402322D0 (sv) * 2004-09-22 2004-09-22 Amersham Biosciences Ab Method of preparing a chromatography matrix
CA2583578C (en) 2004-10-21 2014-04-01 Ge Healthcare Bio-Sciences Ab Chromatography ligand
WO2006065208A1 (en) * 2004-12-14 2006-06-22 Ge Healthcare Bio-Sciences Ab Purification of immunoglobulins
US8728828B2 (en) * 2004-12-22 2014-05-20 Ge Healthcare Bio-Sciences Ab Purification of immunoglobulins
WO2006085806A1 (en) * 2005-02-14 2006-08-17 Ge Healthcare Bio-Sciences Ab Liquid chromatography column
CN101218023B (zh) * 2005-07-06 2012-02-08 通用电气健康护理生物科学股份公司 制备分离基质的方法
SE529259C2 (sv) * 2005-08-31 2007-06-12 Ge Healthcare Bio Sciences Ab Tillverkning av kromarografimatriser, en kromarografimatris, en vätskekromatografikolonn, prcess för att isolera målföreningar och användning av en kromarografimatris för vätskekromatografi
SG131016A1 (en) * 2005-09-19 2007-04-26 Millipore Corp Asymmetric porous adsorptive bead
WO2007058599A1 (en) * 2005-11-21 2007-05-24 Ge Healthcare Bio-Sciences Ab Manufacture of a chromatography matrix
US20070161785A1 (en) * 2005-12-05 2007-07-12 Clontech Laboratories, Inc. High density metal ion affinity compositions and methods for making and using the same
US8481298B2 (en) * 2006-09-29 2013-07-09 Ge Healthcare Bio-Sciences Ab Separation matrix for viral purification
ES2586613T3 (es) * 2007-05-04 2016-10-17 Bio-Works Technologies Ab Método para la fabricación de geles de agarosa
EP2165758A4 (en) 2007-05-30 2016-08-03 Kaneka Corp POROUS SUPPORT COMPRISING A FORMYL GROUP, ABSORBENT PRODUCT USING THE POROUS CARRIER, PROCESS FOR PRODUCING THE POROUS CARRIER, AND PROCESS FOR PRODUCING THE ABSORBENT PRODUCT
SG149759A1 (en) 2007-07-10 2009-02-27 Millipore Corp Media for affinity chromatography
CN101765458B (zh) * 2007-07-25 2014-05-28 通用电气健康护理生物科学股份公司 分离基质
JP5504596B2 (ja) 2007-08-31 2014-05-28 Ｊｎｃ株式会社 多孔性セルロースゲル、その製造方法及びその用途
CN101939094B (zh) * 2008-02-05 2013-11-20 通用电气健康护理生物科学股份公司 分离介质的制备方法
EP2488295A1 (en) * 2009-10-12 2012-08-22 GE Healthcare Bio-Sciences AB Separation matrices
US9352298B2 (en) 2010-12-14 2016-05-31 Jsr Corporation Method for producing polymer particles, and polymer particles
EP2831096B1 (en) 2012-03-28 2020-04-29 GE Healthcare BioProcess R&D AB Affinity chromatography matrix
EP2919902B1 (en) 2012-11-13 2020-01-01 GE Healthcare BioProcess R&D AB Multimodal anion exchange matrices
WO2014092636A1 (en) 2012-12-14 2014-06-19 Ge Healthcare Bio-Sciences Ab Method for cleaning of packed bed chromatography columns
ES2859723T3 (es) * 2012-12-28 2021-10-04 Nalco Co Tratamiento químico para mejorar la separación y lavado del lodo rojo en el proceso Bayer
JPWO2014157606A1 (ja) * 2013-03-29 2017-02-16 国立大学法人京都大学 架橋された疎水化多糖ナノゲル粒子とその製造方法
US10221211B2 (en) 2013-09-27 2019-03-05 Kaneka Corporation Process for producing porous cellulose beads using alkali aqueous solution
RU2665442C2 (ru) * 2013-10-10 2018-08-29 ДжиИ Хелткер Биопроцесс АрЭндДи АБ Способ получения хроматографического материала
JP5883068B2 (ja) * 2014-05-19 2016-03-09 株式会社カネカ 多孔質担体、およびそれを用いた精製用吸着体、およびそれらの製造方法、およびそれらを用いた精製方法
WO2015197338A1 (en) 2014-06-24 2015-12-30 Ge Healthcare Bio-Sciences Ab Chromatography method
US11566082B2 (en) 2014-11-17 2023-01-31 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
CN106140038B (zh) * 2015-04-08 2019-07-12 通用电气公司 制备聚合物微粒的方法和装置
GB201509677D0 (en) 2015-06-04 2015-07-22 Ge Healthcare Bio Sciences Ab Manufacturing process for polysaccharide beads
GB201515339D0 (en) * 2015-08-28 2015-10-14 Ge Healthcare Bio Sciences Ab A seperation matrix and a method of seperating antibodies
US10427950B2 (en) 2015-12-04 2019-10-01 Ecolab Usa Inc. Recovery of mining processing product using boronic acid-containing polymers
EP3439780B1 (en) 2016-04-06 2024-07-03 Cytiva BioProcess R&D AB Chromatography matrix
US10730908B2 (en) 2016-05-11 2020-08-04 Ge Healthcare Bioprocess R&D Ab Separation method
US10513537B2 (en) 2016-05-11 2019-12-24 Ge Healthcare Bioprocess R&D Ab Separation matrix
JP7031934B2 (ja) 2016-05-11 2022-03-08 サイティバ・バイオプロセス・アールアンドディ・アクチボラグ 分離マトリックス
WO2017194593A1 (en) 2016-05-11 2017-11-16 Ge Healthcare Bioprocess R&D Ab Method of cleaning and/or sanitizing a separation matrix
WO2017194592A1 (en) 2016-05-11 2017-11-16 Ge Healthcare Bioprocess R&D Ab Method of storing a separation matrix
US10654887B2 (en) * 2016-05-11 2020-05-19 Ge Healthcare Bio-Process R&D Ab Separation matrix
US10703774B2 (en) * 2016-09-30 2020-07-07 Ge Healthcare Bioprocess R&D Ab Separation method
US10889615B2 (en) 2016-05-11 2021-01-12 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
CN107537412B (zh) 2016-06-27 2021-06-01 思拓凡生物工艺研发有限公司 制备聚合物微球的方法和系统
US12448411B2 (en) 2016-09-30 2025-10-21 Cytiva Bioprocess R&D Ab Separation method
GB201703116D0 (en) 2017-02-27 2017-04-12 Ge Healthcare Bioprocess R&D Ab A seperation matrix and a method of seperating antibodies
GB201708277D0 (en) 2017-05-24 2017-07-05 Ge Healthcare A Recombinant protein
GB201710130D0 (en) 2017-06-26 2017-08-09 Ge Healthcare Bioprocess R & D Ab A Method of seperation
EP3689893A4 (en) 2017-09-25 2021-12-15 JSR Corporation IMMUNOGLOBULIN-BINDING PROTEIN AND AFFINITY CARRIERS THEREFORE
JP7159175B2 (ja) 2017-09-25 2022-10-24 Jsr株式会社 イムノグロブリン結合タンパク質、及びそれを用いたアフィニティー担体
GB2573133A (en) * 2018-04-25 2019-10-30 Ge Healthcare Bioprocess R&D Ab Separation matrix and method of separation
GB201810690D0 (en) 2018-06-29 2018-08-15 Ge Healthcare Bioprocess R&D Ab Chromatography beads, production and use thereof
EP3842536A4 (en) 2018-08-24 2023-01-18 JSR Corporation IMMUNOGLOBULIN-BINDING PROTEIN AND AFFINITY CARRIER WITH IT
GB201820806D0 (en) 2018-12-20 2019-02-06 Ge Healthcare Bioprocess R&D Ab Large pore agarose
WO2020221781A1 (en) 2019-04-29 2020-11-05 Cytiva Bioprocess R&D Ab Method for separation of antibodies or antibody fragments being devoid of an fc region capable of binding to protein a
GB201905919D0 (en) 2019-04-29 2019-06-12 Ge Healthcare Bioprocess R & D Ab Method of manufacturing agar or agarose beads
GB202018588D0 (en) 2020-11-26 2021-01-13 Cytiva Bioprocess R & D Ab Separation matrix
CN116802152A (zh) 2021-02-12 2023-09-22 埃科莱布美国股份有限公司 使用硼酸官能化化合物纯化铝土矿矿石
GB202109246D0 (en) 2021-06-28 2021-08-11 Cytiva Bioprocess R & D Ab A method of separating bispecific antibodies
GB202110014D0 (en) 2021-07-12 2021-08-25 Cytiva Bioprocess R & D Ab A method for separating adeno-associated virus capsids, compositions obtained by said method and uses thereof
SE545486C2 (en) 2021-07-15 2023-09-26 Bio Works Tech Ab Method for the manufacture of agar or agarose beads using vegetable oil
GB202113626D0 (en) 2021-09-24 2021-11-10 Cytiva Bioprocess R & D Ab FC binding polypeptides
KR20240120721A (ko) 2021-12-07 2024-08-07 씨티바 바이오프로세스 알＆디 에이비 분리 매트릭스 및 표적 분자를 분리하는 방법
GB202202777D0 (en) 2022-03-01 2022-04-13 Cytiva Bioprocess R & D Ab A method for separating supercoiled plasmid DNA
GB202203478D0 (en) 2022-03-14 2022-04-27 Cytiva Bioprocess R & D Ab Vh3 binding polypeptides
GB202203640D0 (en) 2022-03-16 2022-04-27 Cytiva Bioprocess R & D Ab Alkali-stabilized kappa light chain-binding separation matrix
GB202206123D0 (en) 2022-04-27 2022-06-08 Cytiva Bioprocess R & D Ab A pre-screening method and a method for separating adeno-associated virus capsids
GB202214280D0 (en) 2022-09-29 2022-11-16 Cytiva Vioprocess R&D Ab Chromatography ligand and chromatography material, and uses thereof
GB202215814D0 (en) 2022-10-26 2022-12-07 Cytiva Bioprocess R & D Ab A chromatography device, system, and use thereof for analytic separation
WO2024217979A1 (en) 2023-04-19 2024-10-24 Cytiva Bioprocess R&D Ab A method for purification of extracellular vesicles or enveloped viruses by means of size exclusion chromatography
WO2024256192A1 (en) 2023-06-13 2024-12-19 Cytiva Bioprocess R&D Ab Purification of enveloped or membranous biological particles
US12312447B2 (en) 2023-06-19 2025-05-27 Zhejiang Triple Win New Material Co., Ltd. Preparation method for polysaccharide spherical gel resin
CN121712792A (zh) 2023-08-14 2026-03-20 思拓凡生物工艺研发有限公司 Vh3结合分离基质和其使用方法
CN121772964A (zh) 2023-09-01 2026-03-31 漂莱特公司 具有提高的线性流速的用于液相色谱的分离基质和方法
CN121843970A (zh) 2023-09-12 2026-04-10 思拓凡生物工艺研发有限公司 用于寡核苷酸和肽的固相合成的载体材料
KR102741170B1 (ko) * 2023-10-13 2024-12-10 퓨리오젠 주식회사 다공성 아가 또는 아가로스 비드 및 이의 제조방법
EP4541814A1 (en) 2023-10-20 2025-04-23 Cytiva BioProcess R&D AB Stabilized polypeptides
EP4541444A1 (en) 2023-10-20 2025-04-23 Cytiva BioProcess R&D AB Fusion protein for affinity capture
WO2025083267A1 (en) 2023-10-20 2025-04-24 Cytiva Bioprocess R&D Ab Aav9 binding polypeptides
WO2025186218A1 (en) 2024-03-04 2025-09-12 Cytiva Bioprocess R&D Ab Purification and analysis of rna
WO2025202371A1 (en) 2024-03-27 2025-10-02 Cytiva Bioprocess R&D Ab Preparation of circular rna
WO2026057420A1 (en) 2024-09-10 2026-03-19 Cytiva Bioprocess R&D Ab Affinity ligand for purification of antibodies of isotype iga
EP4717704A1 (en) 2024-09-26 2026-04-01 Cytiva BioProcess R&D AB Novel protein a ligand that enables milder elution

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3860573A (en) * 1971-10-01 1975-01-14 Orion Yhtymae Oy Method for cross-linking agarose or agar
US3873514A (en) 1974-05-17 1975-03-25 Bio Rad Laboratories Preparation of gel for affinity chromatography
SE449225B (sv) * 1980-12-18 1987-04-13 Gelinnovation Hb Gelprodukt baserad pa partiklar innehallande galaktan for separationsendamal, molekyl- och partikelimmobilisering
SE8205908D0 (sv) * 1982-10-18 1982-10-18 Pharmacia Diagnostics Ab Sett att bilda polymerskikt
SE437270B (sv) * 1983-07-19 1985-02-18 Pharmacia Ab Separationsmaterial av tverbunden agaros och dess framstellning separationsmaterial av tverbunden agaros och dess framstellning
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
SE458525B (sv) * 1985-05-23 1989-04-10 Pharmacia Ab Foerfarande foer tvaerbindning av en poroes agar- eller agarosgel
CA1329800C (en) * 1987-12-29 1994-05-24 Hiroaki Takayanagi Composite separating agent
EP0610441A4 (en) * 1991-10-29 1996-01-10 Clover Cons Ltd CROSSLINKABLE POLYSACCHARIDES, POLYCATIONS AND LIPIDS CAN BE USED TO ENCODE AND DISPENSE MEDICINAL PRODUCTS.
SE9200827D0 (sv) * 1992-03-18 1992-03-18 Pharmacia Lkb Biotech Supet porous polysaccharide gels
US5371208A (en) * 1992-12-30 1994-12-06 Guest Elchrom Scientific Ltd. Preparation of cross-linked linear polysaccharide polymers as gels for electrophoresis
US5785832A (en) * 1995-07-26 1998-07-28 Chiari; Marcella Covalently cross-linked, mixed-bed agarose-polyacrylamide matrices for electrophoresis and chromatography
US5840877A (en) * 1996-09-05 1998-11-24 Guest Elchrom Scientific Electrophoresis gels of enhanced selectivity
SE9700769D0 (sv) * 1997-03-04 1997-03-04 Pharmacia Biotech Ab Matriser för separation och separation som utnyttjar matriserna

Also Published As

Publication number Publication date
JP4081143B2 (ja) 2008-04-23
EP0892815A1 (en) 1999-01-27
ES2217413T3 (es) 2004-11-01
AU2417897A (en) 1997-10-29
DE69728141T2 (de) 2005-02-17
US6602990B1 (en) 2003-08-05
EP0892815B1 (en) 2004-03-17
SE9601368D0 (sv) 1996-04-11
AU726086B2 (en) 2000-11-02
ATE261992T1 (de) 2004-04-15
DE69728141D1 (de) 2004-04-22
WO1997038018A1 (en) 1997-10-16
JP2000508361A (ja) 2000-07-04

Similar Documents

Publication Publication Date Title
DK0892815T3 (da) Fremgangsmåde til fremstilling af en porøs tværbundet polysaccharidgel og dennes anvendelse som gelfiltreringsmedium og ved chromatografi
DK0991705T3 (da) Åbenporede, bionedbrydelige matricer
ATE57475T1 (de) Quervernetzte, poren enthaltende mikrofibrillierte cellulose, hergestellt durch gefrieren und loesungsmittelaustausch.
DK1282663T3 (da) Gel af et poly-a-1,4-glucan og stivelse
PT910412E (pt) Hidrogeis hidrolisaveis para libertacao controlada
DK0550450T3 (da) Anvendelse af tværbundne krystaller som ny fremgangsmåde til immobilisering af enzymer
DK0932444T3 (da) Anvendelse af modificeret stivelse som et middel til at danne en termoreversibel gel
AU2002326633A1 (en) Separation column having a photopolymerized sol-gel component and associated methods
NZ511308A (en) Preparation of cross-linked polysaccharides containing carboxy groups, allowing complete control of the degree of cross-linking
SE0402322D0 (sv) Method of preparing a chromatography matrix
PT809110E (pt) Microparticulas macromoleculares e metodos de producao
DE60212374D1 (de) Vernetzung der stärke
NO20013691L (no) Bindemiddel
FR2330695B3 (enExample)
DK0952959T3 (da) Polyhalophosphazenopløsninger, som er stabile overfor geldannelse
SE9803448D0 (sv) Polysaccharide based absorbent polymer material
NO160926C (no) Fremgangsmaate til fremstilling av en polymerdispersjon, og anvendelse av denne som bindemiddel.
ATE469936T1 (de) Modifiziertes polymer und modifizierte polymermembran
DE69606303D1 (de) Fotochemisch vernetzte polysaccharidderivate ohne photopolymerisierbaren funktionellen gruppen
RU94010864A (ru) Способ получения инсулинсодержащих полимерных гидрогелей
SE0004928D0 (sv) A method for the manufacturing of porous material
BR9808110A (pt) Processo para preparar um xerogel baseado em poliisocianato, dito xerogel, e, uso do mesmo
WO2003023796A3 (en) Method of making an electret
CA2251050A1 (en) Process for the production of a porous cross-linked polysaccharide gel and its use as a gel filtration media and in chromatography
DK159139C (da) Fremgangsmaade til fremstilling af flade emner, saasom luvforsynede maatter