DK0888289T3 - Antikonvulsive, enantiomore aminosyrederivater - Google Patents

Antikonvulsive, enantiomore aminosyrederivater

Info

Publication number
DK0888289T3
DK0888289T3 DK97916897T DK97916897T DK0888289T3 DK 0888289 T3 DK0888289 T3 DK 0888289T3 DK 97916897 T DK97916897 T DK 97916897T DK 97916897 T DK97916897 T DK 97916897T DK 0888289 T3 DK0888289 T3 DK 0888289T3
Authority
DK
Denmark
Prior art keywords
anticonvulsant
enantiomore
amino acid
acid derivatives
animal
Prior art date
Application number
DK97916897T
Other languages
Danish (da)
English (en)
Inventor
Harold Kohn
Original Assignee
Res Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21760388&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0888289(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Res Corp Technologies Inc filed Critical Res Corp Technologies Inc
Application granted granted Critical
Publication of DK0888289T3 publication Critical patent/DK0888289T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK97916897T 1996-03-15 1997-03-17 Antikonvulsive, enantiomore aminosyrederivater DK0888289T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1352296P 1996-03-15 1996-03-15
PCT/US1997/004579 WO1997033861A1 (en) 1996-03-15 1997-03-17 Anticonvulsant enantiomeric amino acid derivatives

Publications (1)

Publication Number Publication Date
DK0888289T3 true DK0888289T3 (da) 2001-09-03

Family

ID=21760388

Family Applications (2)

Application Number Title Priority Date Filing Date
DK97916897T DK0888289T3 (da) 1996-03-15 1997-03-17 Antikonvulsive, enantiomore aminosyrederivater
DK00109377T DK1038522T3 (da) 1996-03-15 1997-03-17 Antikonvulsive enantiomere aminosyrederivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK00109377T DK1038522T3 (da) 1996-03-15 1997-03-17 Antikonvulsive enantiomere aminosyrederivater

Country Status (12)

Country Link
EP (2) EP1038522B1 (es)
JP (1) JP3145414B2 (es)
AT (2) ATE202079T1 (es)
AU (1) AU718577B2 (es)
CA (1) CA2248317C (es)
DE (3) DE122009000010I2 (es)
DK (2) DK0888289T3 (es)
ES (2) ES2157567T3 (es)
FR (1) FR09C0006I2 (es)
NL (1) NL300376I1 (es)
PT (2) PT1038522E (es)
WO (1) WO1997033861A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048899A (en) * 1997-03-17 2000-04-11 Research Corporation Tech., Inc. Anticonvulsant enantiomeric amino acid derivatives
EP1642889A1 (en) * 2004-10-02 2006-04-05 Schwarz Pharma Ag Improved synthesis scheme for lacosamide
EP1873527A1 (en) 2006-06-30 2008-01-02 Schwarz Pharma Ag Method for identifying CRMP modulators
US8093426B2 (en) * 2007-12-04 2012-01-10 Ranbaxy Laboratories Limited Intermediate compounds and their use in preparation of lacosamide
DE102008059155A1 (de) 2008-11-27 2010-06-02 Ratiopharm Gmbh Trockenverarbeitung und neue Formen von Lacosamid
EP2462107A1 (en) 2009-08-06 2012-06-13 Medichem, S.A. Solid forms of an n-(phenylmethyl)propanamide derivative and processes of preparation
JP5564570B2 (ja) * 2009-09-25 2014-07-30 カディラ・ヘルスケア・リミテッド ラコサミドおよびその中間体の調製方法
IT1398044B1 (it) * 2010-01-29 2013-02-07 Archimica Srl Processo per la preparazione della lacosamide
EP2534128A1 (en) 2010-02-08 2012-12-19 Natco Pharma Limited A process for the preparation of lacosamide
WO2011099033A1 (en) * 2010-02-09 2011-08-18 Msn Laboratories Limited Process for preparing (r)-2-acetamido-n-benzyl-3-methoxy-propionamide
EP2399901A1 (en) 2010-06-23 2011-12-28 Archimica GmbH Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide
EP2621893A1 (en) 2010-10-01 2013-08-07 UCB Pharma GmbH Process for the preparation of amino acid derivatives
EP2627639B1 (en) * 2010-10-15 2021-12-22 Nektar Therapeutics N-optionally substituted aryl-2-oligomer-3-alkoxypropionamides
EP2444390B1 (en) 2010-10-19 2017-02-01 Euticals GmbH Process for producing Lacosamide
EP2468261A1 (en) 2010-12-02 2012-06-27 UCB Pharma GmbH Formulation of lacosamide
US20130251813A1 (en) 2010-12-02 2013-09-26 Ucb Pharma Gmbh Formulation of lacosamide
CN104771356A (zh) * 2014-01-09 2015-07-15 山东方明药业集团股份有限公司 一种拉科酰胺注射液及其制备方法
US11278634B1 (en) 2021-02-12 2022-03-22 Extrovis Ag Stable parenteral composition of lacosamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378729A (en) * 1985-02-15 1995-01-03 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
ATE62222T1 (de) * 1985-02-15 1991-04-15 Res Corp Technologies Inc Aminosaeure-derivate und ihre anwendung zur herstellung eines antikrampfmittels.

Also Published As

Publication number Publication date
EP1038522B1 (en) 2004-06-02
DE122009000010I2 (de) 2010-10-21
EP1038522A3 (en) 2003-01-15
AU718577B2 (en) 2000-04-13
DE69729392D1 (de) 2004-07-08
DK1038522T3 (da) 2004-10-11
EP1038522A2 (en) 2000-09-27
PT888289E (pt) 2001-09-28
EP0888289A1 (en) 1999-01-07
ATE268169T1 (de) 2004-06-15
DE69705210T2 (de) 2001-09-20
CA2248317A1 (en) 1997-09-18
AU2539497A (en) 1997-10-01
DE69705210D1 (de) 2001-07-19
FR09C0006I1 (es) 2009-04-17
PT1038522E (pt) 2004-10-29
EP0888289B1 (en) 2001-06-13
JP2000505476A (ja) 2000-05-09
FR09C0006I2 (fr) 2009-12-18
JP3145414B2 (ja) 2001-03-12
NL300376I1 (nl) 2009-05-06
ATE202079T1 (de) 2001-06-15
DE122009000010I1 (de) 2009-05-20
ES2157567T3 (es) 2001-08-16
CA2248317C (en) 2003-12-02
WO1997033861A1 (en) 1997-09-18
ES2218024T3 (es) 2004-11-16
DE69729392T2 (de) 2005-06-02

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