FR09C0006I1 - - Google Patents
Info
- Publication number
- FR09C0006I1 FR09C0006I1 FR09C0006C FR09C0006I1 FR 09C0006 I1 FR09C0006 I1 FR 09C0006I1 FR 09C0006 C FR09C0006 C FR 09C0006C FR 09C0006 I1 FR09C0006 I1 FR 09C0006I1
- Authority
- FR
- France
- Prior art keywords
- animal
- unsubstituted
- chem
- administering
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1352296P | 1996-03-15 | 1996-03-15 | |
PCT/US1997/004579 WO1997033861A1 (en) | 1996-03-15 | 1997-03-17 | Anticonvulsant enantiomeric amino acid derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
FR09C0006I1 true FR09C0006I1 (es) | 2009-04-17 |
FR09C0006I2 FR09C0006I2 (fr) | 2009-12-18 |
Family
ID=21760388
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR09C0006C Active FR09C0006I2 (fr) | 1996-03-15 | 2009-02-26 | Derives aminoacides enantiomeriques ayant un effet anti-convulsif |
Country Status (12)
Country | Link |
---|---|
EP (2) | EP1038522B1 (es) |
JP (1) | JP3145414B2 (es) |
AT (2) | ATE268169T1 (es) |
AU (1) | AU718577B2 (es) |
CA (1) | CA2248317C (es) |
DE (3) | DE122009000010I2 (es) |
DK (2) | DK0888289T3 (es) |
ES (2) | ES2157567T3 (es) |
FR (1) | FR09C0006I2 (es) |
NL (1) | NL300376I1 (es) |
PT (2) | PT888289E (es) |
WO (1) | WO1997033861A1 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6048899A (en) * | 1997-03-17 | 2000-04-11 | Research Corporation Tech., Inc. | Anticonvulsant enantiomeric amino acid derivatives |
EP1642889A1 (en) * | 2004-10-02 | 2006-04-05 | Schwarz Pharma Ag | Improved synthesis scheme for lacosamide |
EP1873527A1 (en) | 2006-06-30 | 2008-01-02 | Schwarz Pharma Ag | Method for identifying CRMP modulators |
US8093426B2 (en) | 2007-12-04 | 2012-01-10 | Ranbaxy Laboratories Limited | Intermediate compounds and their use in preparation of lacosamide |
DE102008059155A1 (de) | 2008-11-27 | 2010-06-02 | Ratiopharm Gmbh | Trockenverarbeitung und neue Formen von Lacosamid |
AR080275A1 (es) | 2009-08-06 | 2012-03-28 | Medichem Sa | Formas solidas de un derivado de n-( fenilmetil) propanamida y procedimientos de preparacion |
JP5564570B2 (ja) * | 2009-09-25 | 2014-07-30 | カディラ・ヘルスケア・リミテッド | ラコサミドおよびその中間体の調製方法 |
IT1398044B1 (it) * | 2010-01-29 | 2013-02-07 | Archimica Srl | Processo per la preparazione della lacosamide |
KR20120128667A (ko) | 2010-02-08 | 2012-11-27 | 낫코 파마 리미티드 | 라코사미드의 제조방법 |
WO2011099033A1 (en) * | 2010-02-09 | 2011-08-18 | Msn Laboratories Limited | Process for preparing (r)-2-acetamido-n-benzyl-3-methoxy-propionamide |
EP2399901A1 (en) | 2010-06-23 | 2011-12-28 | Archimica GmbH | Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide |
EP2621893A1 (en) | 2010-10-01 | 2013-08-07 | UCB Pharma GmbH | Process for the preparation of amino acid derivatives |
WO2012051551A1 (en) * | 2010-10-15 | 2012-04-19 | Nektar Therapeutics | N-optionally substituted aryl-2-oligomer-3-alkoxypropionamides |
HUE031138T2 (en) | 2010-10-19 | 2017-06-28 | Euticals Gmbh | A method of producing lacosamide |
WO2012072256A2 (en) | 2010-12-02 | 2012-06-07 | Ucb Pharma Gmbh | Once daily formulation of lacosamide |
EP2468261A1 (en) | 2010-12-02 | 2012-06-27 | UCB Pharma GmbH | Formulation of lacosamide |
CN104771356A (zh) * | 2014-01-09 | 2015-07-15 | 山东方明药业集团股份有限公司 | 一种拉科酰胺注射液及其制备方法 |
US11278634B1 (en) | 2021-02-12 | 2022-03-22 | Extrovis Ag | Stable parenteral composition of lacosamide |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0194464B1 (en) * | 1985-02-15 | 1991-04-03 | Research Corporation Technologies, Inc. (a Delaware corp.) | Amino acid derivatives and use thereof for the preparation of an anticonvulsant |
US5378729A (en) * | 1985-02-15 | 1995-01-03 | Research Corporation Technologies, Inc. | Amino acid derivative anticonvulsant |
-
1997
- 1997-03-17 ES ES97916897T patent/ES2157567T3/es not_active Expired - Lifetime
- 1997-03-17 DK DK97916897T patent/DK0888289T3/da active
- 1997-03-17 CA CA002248317A patent/CA2248317C/en not_active Expired - Lifetime
- 1997-03-17 EP EP00109377A patent/EP1038522B1/en not_active Expired - Lifetime
- 1997-03-17 AU AU25394/97A patent/AU718577B2/en not_active Expired
- 1997-03-17 DE DE122009000010C patent/DE122009000010I2/de active Active
- 1997-03-17 DE DE69729392T patent/DE69729392T2/de not_active Expired - Lifetime
- 1997-03-17 PT PT97916897T patent/PT888289E/pt unknown
- 1997-03-17 DK DK00109377T patent/DK1038522T3/da active
- 1997-03-17 AT AT00109377T patent/ATE268169T1/de active
- 1997-03-17 AT AT97916897T patent/ATE202079T1/de active
- 1997-03-17 DE DE69705210T patent/DE69705210T2/de not_active Expired - Lifetime
- 1997-03-17 PT PT00109377T patent/PT1038522E/pt unknown
- 1997-03-17 EP EP97916897A patent/EP0888289B1/en not_active Expired - Lifetime
- 1997-03-17 JP JP53292897A patent/JP3145414B2/ja not_active Expired - Lifetime
- 1997-03-17 WO PCT/US1997/004579 patent/WO1997033861A1/en active IP Right Grant
- 1997-03-17 ES ES00109377T patent/ES2218024T3/es not_active Expired - Lifetime
-
2009
- 2009-02-16 NL NL300376C patent/NL300376I1/nl unknown
- 2009-02-26 FR FR09C0006C patent/FR09C0006I2/fr active Active
Also Published As
Publication number | Publication date |
---|---|
AU2539497A (en) | 1997-10-01 |
DK0888289T3 (da) | 2001-09-03 |
ES2157567T3 (es) | 2001-08-16 |
DE122009000010I2 (de) | 2010-10-21 |
WO1997033861A1 (en) | 1997-09-18 |
DE122009000010I1 (de) | 2009-05-20 |
EP1038522A3 (en) | 2003-01-15 |
NL300376I1 (nl) | 2009-05-06 |
DK1038522T3 (da) | 2004-10-11 |
DE69729392D1 (de) | 2004-07-08 |
FR09C0006I2 (fr) | 2009-12-18 |
PT888289E (pt) | 2001-09-28 |
JP2000505476A (ja) | 2000-05-09 |
ATE268169T1 (de) | 2004-06-15 |
DE69705210T2 (de) | 2001-09-20 |
EP1038522B1 (en) | 2004-06-02 |
JP3145414B2 (ja) | 2001-03-12 |
DE69705210D1 (de) | 2001-07-19 |
AU718577B2 (en) | 2000-04-13 |
CA2248317C (en) | 2003-12-02 |
EP0888289A1 (en) | 1999-01-07 |
PT1038522E (pt) | 2004-10-29 |
EP0888289B1 (en) | 2001-06-13 |
ES2218024T3 (es) | 2004-11-16 |
EP1038522A2 (en) | 2000-09-27 |
ATE202079T1 (de) | 2001-06-15 |
CA2248317A1 (en) | 1997-09-18 |
DE69729392T2 (de) | 2005-06-02 |
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