ATE62222T1 - Aminosaeure-derivate und ihre anwendung zur herstellung eines antikrampfmittels. - Google Patents
Aminosaeure-derivate und ihre anwendung zur herstellung eines antikrampfmittels.Info
- Publication number
- ATE62222T1 ATE62222T1 AT86101865T AT86101865T ATE62222T1 AT E62222 T1 ATE62222 T1 AT E62222T1 AT 86101865 T AT86101865 T AT 86101865T AT 86101865 T AT86101865 T AT 86101865T AT E62222 T1 ATE62222 T1 AT E62222T1
- Authority
- AT
- Austria
- Prior art keywords
- lower alkyl
- sempk
- agent
- preparation
- amino acid
- Prior art date
Links
- 150000003862 amino acid derivatives Chemical class 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000001773 anti-convulsant effect Effects 0.000 abstract 2
- 239000001961 anticonvulsive agent Substances 0.000 abstract 2
- 229960003965 antiepileptics Drugs 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70219585A | 1985-02-15 | 1985-02-15 | |
| EP86101865A EP0194464B1 (de) | 1985-02-15 | 1986-02-14 | Aminosäure-Derivate und ihre Anwendung zur Herstellung eines Antikrampfmittels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE62222T1 true ATE62222T1 (de) | 1991-04-15 |
Family
ID=24820226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86101865T ATE62222T1 (de) | 1985-02-15 | 1986-02-14 | Aminosaeure-derivate und ihre anwendung zur herstellung eines antikrampfmittels. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0194464B1 (de) |
| JP (1) | JPH06104649B2 (de) |
| AT (1) | ATE62222T1 (de) |
| AU (1) | AU596573B2 (de) |
| CA (1) | CA1340902C (de) |
| DE (1) | DE3678469D1 (de) |
| DK (1) | DK173553B1 (de) |
| ES (1) | ES8708142A1 (de) |
| GR (1) | GR860455B (de) |
| IE (1) | IE58422B1 (de) |
| PT (1) | PT82032B (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2569186B1 (fr) * | 1984-08-20 | 1986-09-05 | Lafon Labor | Derives de 1-(n-(a-amino-a-methylacetyl)-aminophenyl)-2-amino-propanone, procede de preparation et utilisation en therapeutique |
| US5378729A (en) | 1985-02-15 | 1995-01-03 | Research Corporation Technologies, Inc. | Amino acid derivative anticonvulsant |
| US5654301A (en) * | 1985-02-15 | 1997-08-05 | Research Corporation Technologies, Inc. | Amino acid derivative anticonvulsant |
| NZ222045A (en) * | 1986-08-21 | 1989-10-27 | Res Corp Technologies Inc | From diamides up to tetrapeptides for use as anticanvulsants |
| NZ233728A (en) * | 1989-05-19 | 1993-04-28 | Res Corp Technologies Inc | Amino acid compounds and pharmaceutical compositions thereof |
| ATE133658T1 (de) * | 1991-07-10 | 1996-02-15 | Merck Sharp & Dohme | Aromatische verbindungen diese enthaltende pharmazeutische zusammensetzungen und ihre therapeutische verwendung |
| GB9211193D0 (en) * | 1992-05-27 | 1992-07-08 | Merck Sharp & Dohme | Therapeutic agents |
| WO1994003429A1 (en) * | 1992-07-31 | 1994-02-17 | Merck Sharp & Dohme Limited | Substituted amines as tachykinin receptor antagonists |
| EP1038522B1 (de) * | 1996-03-15 | 2004-06-02 | Research Corporation Technologies, Inc | Antikonvulsive enantiomerische Aminosäurederivate |
| US5773475A (en) | 1997-03-17 | 1998-06-30 | Research Corporation Technologies, Inc. | Anticonvulsant enantiomeric amino acid derivatives |
| US6048899A (en) * | 1997-03-17 | 2000-04-11 | Research Corporation Tech., Inc. | Anticonvulsant enantiomeric amino acid derivatives |
| ATE320249T1 (de) | 1997-07-08 | 2006-04-15 | Ono Pharmaceutical Co | Aminosäurederivate |
| US6028102A (en) * | 1998-02-24 | 2000-02-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Anticonvulsant drugs and pharmaceutical compositions thereof |
| TWI245035B (en) | 1998-06-26 | 2005-12-11 | Ono Pharmaceutical Co | Amino acid derivatives and a pharmaceutical composition comprising the derivatives |
| WO2000004005A1 (en) | 1998-07-14 | 2000-01-27 | Ono Pharmaceutical Co., Ltd. | Amino acid derivatives and drugs containing the same as the active ingredient |
| ES2190305B1 (es) * | 2000-05-24 | 2004-07-01 | Medichem S.A. | Compuestos intermedios para la preparacion de mirtazapina y sus procedimientos de obtencion. |
| EP1604656A1 (de) | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Neue Verwendung von Peptidverbindungen zur Behandlung von amyotropher Lateralsklerose (ALS) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2676188A (en) * | 1950-12-16 | 1954-04-20 | American Home Prod | Acylated glycinamides |
| GB1051220A (de) * | 1963-03-21 | |||
| IE33790B1 (en) * | 1968-06-04 | 1974-10-30 | Beecham Group Ltd | Derivatives of n-acylaminoacid amides |
| US3707559A (en) * | 1971-05-14 | 1972-12-26 | Searle & Co | N-acyl phenylalanine amides |
| JPS557242A (en) * | 1978-06-30 | 1980-01-19 | Tanabe Seiyaku Co Ltd | Phenethylamine derivative |
| FR2480747A1 (fr) * | 1980-04-17 | 1981-10-23 | Roques Bernard | Derives d'acides amines et leur application therapeutique |
| FR2489319A1 (fr) * | 1980-08-27 | 1982-03-05 | Clin Midy | Derives de l'acide amino-4 butyrique et les medicaments, actifs notamment sur le systeme nerveux central, en contenant |
-
1986
- 1986-02-14 DK DK198600726A patent/DK173553B1/da not_active IP Right Cessation
- 1986-02-14 CA CA000501869A patent/CA1340902C/en not_active Expired - Lifetime
- 1986-02-14 DE DE8686101865T patent/DE3678469D1/de not_active Expired - Lifetime
- 1986-02-14 EP EP86101865A patent/EP0194464B1/de not_active Expired - Lifetime
- 1986-02-14 AT AT86101865T patent/ATE62222T1/de not_active IP Right Cessation
- 1986-02-14 IE IE41186A patent/IE58422B1/en not_active IP Right Cessation
- 1986-02-15 ES ES552348A patent/ES8708142A1/es not_active Expired
- 1986-02-15 JP JP61031742A patent/JPH06104649B2/ja not_active Expired - Lifetime
- 1986-02-17 AU AU53711/86A patent/AU596573B2/en not_active Expired
- 1986-02-17 GR GR860455A patent/GR860455B/el unknown
- 1986-02-17 PT PT82032A patent/PT82032B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT82032B (pt) | 1988-07-01 |
| ES552348A0 (es) | 1987-10-16 |
| DE3678469D1 (de) | 1991-05-08 |
| PT82032A (en) | 1986-03-01 |
| DK72686A (da) | 1986-08-16 |
| JPS61200950A (ja) | 1986-09-05 |
| EP0194464A1 (de) | 1986-09-17 |
| DK72686D0 (da) | 1986-02-14 |
| JPH06104649B2 (ja) | 1994-12-21 |
| GR860455B (en) | 1986-06-18 |
| CA1340902C (en) | 2000-02-22 |
| AU5371186A (en) | 1986-08-21 |
| AU596573B2 (en) | 1990-05-10 |
| ES8708142A1 (es) | 1987-10-16 |
| DK173553B1 (da) | 2001-03-12 |
| EP0194464B1 (de) | 1991-04-03 |
| IE58422B1 (en) | 1993-09-22 |
| IE860411L (en) | 1986-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |