DE3678469D1 - Aminosaeure-derivate und ihre anwendung zur herstellung eines antikrampfmittels. - Google Patents

Aminosaeure-derivate und ihre anwendung zur herstellung eines antikrampfmittels.

Info

Publication number
DE3678469D1
DE3678469D1 DE8686101865T DE3678469T DE3678469D1 DE 3678469 D1 DE3678469 D1 DE 3678469D1 DE 8686101865 T DE8686101865 T DE 8686101865T DE 3678469 T DE3678469 T DE 3678469T DE 3678469 D1 DE3678469 D1 DE 3678469D1
Authority
DE
Germany
Prior art keywords
lower alkyl
spractive
production
amino acid
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686101865T
Other languages
English (en)
Inventor
Harold L Kohn
Darrell Watson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Corp Technologies Inc
Original Assignee
Research Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp Technologies Inc filed Critical Research Corp Technologies Inc
Application granted granted Critical
Publication of DE3678469D1 publication Critical patent/DE3678469D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8686101865T 1985-02-15 1986-02-14 Aminosaeure-derivate und ihre anwendung zur herstellung eines antikrampfmittels. Expired - Lifetime DE3678469D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US70219585A 1985-02-15 1985-02-15

Publications (1)

Publication Number Publication Date
DE3678469D1 true DE3678469D1 (de) 1991-05-08

Family

ID=24820226

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686101865T Expired - Lifetime DE3678469D1 (de) 1985-02-15 1986-02-14 Aminosaeure-derivate und ihre anwendung zur herstellung eines antikrampfmittels.

Country Status (11)

Country Link
EP (1) EP0194464B1 (de)
JP (1) JPH06104649B2 (de)
AT (1) ATE62222T1 (de)
AU (1) AU596573B2 (de)
CA (1) CA1340902C (de)
DE (1) DE3678469D1 (de)
DK (1) DK173553B1 (de)
ES (1) ES8708142A1 (de)
GR (1) GR860455B (de)
IE (1) IE58422B1 (de)
PT (1) PT82032B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2569186B1 (fr) * 1984-08-20 1986-09-05 Lafon Labor Derives de 1-(n-(a-amino-a-methylacetyl)-aminophenyl)-2-amino-propanone, procede de preparation et utilisation en therapeutique
US5378729A (en) * 1985-02-15 1995-01-03 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
US5654301A (en) * 1985-02-15 1997-08-05 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
NZ222045A (en) * 1986-08-21 1989-10-27 Res Corp Technologies Inc From diamides up to tetrapeptides for use as anticanvulsants
CA2017217C (en) * 1989-05-19 2002-02-19 Harold L. Kohn Amino acid derivative anticonvulsant
EP0593615B1 (de) * 1991-07-10 1996-01-31 MERCK SHARP & DOHME LTD. Aromatische verbindungen diese enthaltende pharmazeutische zusammensetzungen und ihre therapeutische verwendung
GB9211193D0 (en) * 1992-05-27 1992-07-08 Merck Sharp & Dohme Therapeutic agents
WO1994003429A1 (en) * 1992-07-31 1994-02-17 Merck Sharp & Dohme Limited Substituted amines as tachykinin receptor antagonists
US5773475A (en) * 1997-03-17 1998-06-30 Research Corporation Technologies, Inc. Anticonvulsant enantiomeric amino acid derivatives
ES2218024T3 (es) * 1996-03-15 2004-11-16 Research Corporation Technologies, Inc Derivados de aminoacido enantiomerico anticonvulsionante.
US6048899A (en) * 1997-03-17 2000-04-11 Research Corporation Tech., Inc. Anticonvulsant enantiomeric amino acid derivatives
EP0997147B1 (de) 1997-07-08 2006-03-15 Ono Pharmaceutical Co., Ltd. Aminosäurederivate
US6028102A (en) * 1998-02-24 2000-02-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Anticonvulsant drugs and pharmaceutical compositions thereof
TWI245035B (en) 1998-06-26 2005-12-11 Ono Pharmaceutical Co Amino acid derivatives and a pharmaceutical composition comprising the derivatives
US6903119B1 (en) 1998-07-14 2005-06-07 Ono Pharmaceutical Co., Ltd. Amino acid derivatives and drugs containing the same as the active ingredient
ES2190305B1 (es) * 2000-05-24 2004-07-01 Medichem S.A. Compuestos intermedios para la preparacion de mirtazapina y sus procedimientos de obtencion.
EP1604656A1 (de) 2004-06-09 2005-12-14 Schwarz Pharma Ag Neue Verwendung von Peptidverbindungen zur Behandlung von amyotropher Lateralsklerose (ALS)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2676188A (en) * 1950-12-16 1954-04-20 American Home Prod Acylated glycinamides
GB1051220A (de) * 1963-03-21
IE33790B1 (en) * 1968-06-04 1974-10-30 Beecham Group Ltd Derivatives of n-acylaminoacid amides
US3707559A (en) * 1971-05-14 1972-12-26 Searle & Co N-acyl phenylalanine amides
JPS557242A (en) * 1978-06-30 1980-01-19 Tanabe Seiyaku Co Ltd Phenethylamine derivative
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
FR2489319A1 (fr) * 1980-08-27 1982-03-05 Clin Midy Derives de l'acide amino-4 butyrique et les medicaments, actifs notamment sur le systeme nerveux central, en contenant

Also Published As

Publication number Publication date
AU596573B2 (en) 1990-05-10
EP0194464B1 (de) 1991-04-03
JPS61200950A (ja) 1986-09-05
ES552348A0 (es) 1987-10-16
PT82032A (en) 1986-03-01
DK173553B1 (da) 2001-03-12
CA1340902C (en) 2000-02-22
EP0194464A1 (de) 1986-09-17
PT82032B (pt) 1988-07-01
JPH06104649B2 (ja) 1994-12-21
DK72686A (da) 1986-08-16
DK72686D0 (da) 1986-02-14
ATE62222T1 (de) 1991-04-15
IE860411L (en) 1986-08-15
IE58422B1 (en) 1993-09-22
AU5371186A (en) 1986-08-21
ES8708142A1 (es) 1987-10-16
GR860455B (en) 1986-06-18

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Legal Events

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