FI893901A - Menetelmä tetrasyklisten masennuslääkkeiden valmistamiseksi - Google Patents

Menetelmä tetrasyklisten masennuslääkkeiden valmistamiseksi Download PDF

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Publication number
FI893901A
FI893901A FI893901A FI893901A FI893901A FI 893901 A FI893901 A FI 893901A FI 893901 A FI893901 A FI 893901A FI 893901 A FI893901 A FI 893901A FI 893901 A FI893901 A FI 893901A
Authority
FI
Finland
Prior art keywords
preparation
alkyl
tetracyclic antidepressants
different substituents
substituents
Prior art date
Application number
FI893901A
Other languages
English (en)
Swedish (sv)
Other versions
FI91638C (fi
FI91638B (fi
FI893901A0 (fi
Inventor
Johannes Hubertus Wieringa
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI893901A0 publication Critical patent/FI893901A0/fi
Publication of FI893901A publication Critical patent/FI893901A/fi
Application granted granted Critical
Publication of FI91638B publication Critical patent/FI91638B/fi
Publication of FI91638C publication Critical patent/FI91638C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI893901A 1988-08-26 1989-08-18 Menetelmä tetrasyklisten masennuslääkkeiden valmistamiseksi FI91638C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8802109 1988-08-26
NL8802109 1988-08-26

Publications (4)

Publication Number Publication Date
FI893901A0 FI893901A0 (fi) 1989-08-18
FI893901A true FI893901A (fi) 1990-02-27
FI91638B FI91638B (fi) 1994-04-15
FI91638C FI91638C (fi) 1994-07-25

Family

ID=19852805

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893901A FI91638C (fi) 1988-08-26 1989-08-18 Menetelmä tetrasyklisten masennuslääkkeiden valmistamiseksi

Country Status (16)

Country Link
US (1) US4977158A (fi)
EP (1) EP0357126B1 (fi)
JP (1) JP2521157B2 (fi)
KR (1) KR900003177A (fi)
AT (1) ATE104981T1 (fi)
AU (1) AU618392B2 (fi)
CA (1) CA1325807C (fi)
DE (1) DE68914917T2 (fi)
DK (1) DK415789A (fi)
ES (1) ES2056194T3 (fi)
FI (1) FI91638C (fi)
IE (1) IE62754B1 (fi)
MX (1) MX9203809A (fi)
NZ (1) NZ230128A (fi)
PT (1) PT91555B (fi)
ZA (1) ZA895623B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0726265T3 (da) * 1995-02-08 2001-10-22 Novartis Ag 10-Aminoaliphatyl-dibenz[b,f]oxepiner med antineurodegenerativ virkning
AU2418499A (en) * 1997-12-19 1999-07-12 Akzo Nobel N.V. Org-5222 in the treatment of depression
HRP20020305A8 (en) 2002-04-10 2009-03-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 2-thia-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
HRP20020440B1 (en) 2002-05-21 2008-02-29 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 1-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof
HRP20020452A2 (en) 2002-05-23 2004-02-29 Pliva D D 1,2-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediates for preparation thereof
HRP20030956A2 (en) * 2003-11-21 2005-08-31 Pliva-Istra�iva�ki institut d.o.o. USE OF 1,2-DIAZA-DIBENZO[e,h]AZULENES FOR THE MANU
JP5245428B2 (ja) * 2007-07-06 2013-07-24 住友化学株式会社 トランス−ジベンゾオキセノピロール化合物の製造方法およびその中間体
US20090233959A1 (en) * 2008-02-19 2009-09-17 Adolor Corporation Beloxepin and analogs for the treatment of pain
MX2010009110A (es) * 2008-02-19 2010-11-30 Adolor Corp Beloxepina, sus enantiomeros, y analogos de la misma para el tratamiento de dolor.
US20090233958A1 (en) * 2008-02-19 2009-09-17 Adolor Corporation (+)-beloxepin and methods for its synthesis and use
US20090233957A1 (en) * 2008-02-19 2009-09-17 Adolor Corporation (-)-beloxepin and methods for its synthesis and use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271177A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 2,3,3a,12b-Tetrahydro-1H-dibenzo[2,3;6,7]thiepino[4,5-c]pyrroles and pharmaceutical use thereof
US4158059A (en) * 1976-05-24 1979-06-12 Akzona Incorporated Tension reducing 2,3,4,4a,9,136-hexahydro-dibenz[1,2;5,6]cyclohepta[3,4-c]py
US4271179A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 1,2,3,3a,8,12b-Hexahydro-dibenzo[1,2;5,6]cyclohepta[3,4-C]pyrroles and pharmaceutical use thereof
NL7605526A (nl) * 1976-05-24 1977-11-28 Akzo Nv Nieuwe tetracyclische derivaten.
WO1988000049A1 (en) * 1986-06-26 1988-01-14 Kyowa Hakko Kogyo Co., Ltd. Antiarrhythmic agent

Also Published As

Publication number Publication date
IE892363L (en) 1990-02-26
FI91638C (fi) 1994-07-25
EP0357126B1 (en) 1994-04-27
DK415789A (da) 1990-02-27
FI91638B (fi) 1994-04-15
MX9203809A (es) 1992-07-01
NZ230128A (en) 1990-10-26
AU618392B2 (en) 1991-12-19
DE68914917T2 (de) 1994-08-11
JP2521157B2 (ja) 1996-07-31
IE62754B1 (en) 1995-02-22
PT91555A (pt) 1990-03-08
PT91555B (pt) 1995-05-04
FI893901A0 (fi) 1989-08-18
ZA895623B (en) 1990-05-30
CA1325807C (en) 1994-01-04
EP0357126A1 (en) 1990-03-07
JPH02111776A (ja) 1990-04-24
DE68914917D1 (de) 1994-06-01
ATE104981T1 (de) 1994-05-15
US4977158A (en) 1990-12-11
ES2056194T3 (es) 1994-10-01
AU4002289A (en) 1990-03-01
DK415789D0 (da) 1989-08-23
KR900003177A (ko) 1990-03-23

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: AKZO N.V.