ZA895623B - Tetracyclic antidepressants - Google Patents

Tetracyclic antidepressants

Info

Publication number
ZA895623B
ZA895623B ZA895623A ZA895623A ZA895623B ZA 895623 B ZA895623 B ZA 895623B ZA 895623 A ZA895623 A ZA 895623A ZA 895623 A ZA895623 A ZA 895623A ZA 895623 B ZA895623 B ZA 895623B
Authority
ZA
South Africa
Prior art keywords
alkyl
different substituents
substituents
tetracyclic antidepressants
neuroleptic
Prior art date
Application number
ZA895623A
Other languages
English (en)
Inventor
Johannes Hubertus Wieringa
Hubertus Wieringa Johannes
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of ZA895623B publication Critical patent/ZA895623B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA895623A 1988-08-26 1989-07-24 Tetracyclic antidepressants ZA895623B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8802109 1988-08-26

Publications (1)

Publication Number Publication Date
ZA895623B true ZA895623B (en) 1990-05-30

Family

ID=19852805

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA895623A ZA895623B (en) 1988-08-26 1989-07-24 Tetracyclic antidepressants

Country Status (16)

Country Link
US (1) US4977158A (xx)
EP (1) EP0357126B1 (xx)
JP (1) JP2521157B2 (xx)
KR (1) KR900003177A (xx)
AT (1) ATE104981T1 (xx)
AU (1) AU618392B2 (xx)
CA (1) CA1325807C (xx)
DE (1) DE68914917T2 (xx)
DK (1) DK415789A (xx)
ES (1) ES2056194T3 (xx)
FI (1) FI91638C (xx)
IE (1) IE62754B1 (xx)
MX (1) MX9203809A (xx)
NZ (1) NZ230128A (xx)
PT (1) PT91555B (xx)
ZA (1) ZA895623B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW420672B (en) * 1995-02-08 2001-02-01 Novartis Ag Anti-neurodegeneratively active 10-aminoaliphatyl-dibenz[b,f]oxepines
WO1999032108A1 (en) * 1997-12-19 1999-07-01 Akzo Nobel N.V. Org-5222 in the treatment of depression
HRP20020305A8 (en) 2002-04-10 2009-03-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 2-thia-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
HRP20020440B1 (en) 2002-05-21 2008-02-29 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 1-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof
HRP20020452A2 (en) 2002-05-23 2004-02-29 Pliva D D 1,2-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediates for preparation thereof
HRP20030956A2 (en) * 2003-11-21 2005-08-31 Pliva-Istra�iva�ki institut d.o.o. USE OF 1,2-DIAZA-DIBENZO[e,h]AZULENES FOR THE MANU
JP5245428B2 (ja) * 2007-07-06 2013-07-24 住友化学株式会社 トランス−ジベンゾオキセノピロール化合物の製造方法およびその中間体
US20090233957A1 (en) * 2008-02-19 2009-09-17 Adolor Corporation (-)-beloxepin and methods for its synthesis and use
US20090233959A1 (en) * 2008-02-19 2009-09-17 Adolor Corporation Beloxepin and analogs for the treatment of pain
KR20100137473A (ko) 2008-02-19 2010-12-30 아돌로 코포레이션 동통 치료를 위한 벨록세핀, 이의 거울상이성질체, 및 이의 유사체
US20090233958A1 (en) * 2008-02-19 2009-09-17 Adolor Corporation (+)-beloxepin and methods for its synthesis and use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271179A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 1,2,3,3a,8,12b-Hexahydro-dibenzo[1,2;5,6]cyclohepta[3,4-C]pyrroles and pharmaceutical use thereof
US4158059A (en) * 1976-05-24 1979-06-12 Akzona Incorporated Tension reducing 2,3,4,4a,9,136-hexahydro-dibenz[1,2;5,6]cyclohepta[3,4-c]py
US4271177A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 2,3,3a,12b-Tetrahydro-1H-dibenzo[2,3;6,7]thiepino[4,5-c]pyrroles and pharmaceutical use thereof
NL7605526A (nl) * 1976-05-24 1977-11-28 Akzo Nv Nieuwe tetracyclische derivaten.
AU604726B2 (en) * 1986-06-26 1991-01-03 Kyowa Hakko Kogyo Co. Ltd. Antiarrhythmic agent

Also Published As

Publication number Publication date
IE892363L (en) 1990-02-26
FI893901A (fi) 1990-02-27
EP0357126B1 (en) 1994-04-27
FI91638B (fi) 1994-04-15
DE68914917T2 (de) 1994-08-11
ES2056194T3 (es) 1994-10-01
DE68914917D1 (de) 1994-06-01
PT91555A (pt) 1990-03-08
NZ230128A (en) 1990-10-26
JP2521157B2 (ja) 1996-07-31
AU4002289A (en) 1990-03-01
KR900003177A (ko) 1990-03-23
FI893901A0 (fi) 1989-08-18
PT91555B (pt) 1995-05-04
DK415789A (da) 1990-02-27
EP0357126A1 (en) 1990-03-07
DK415789D0 (da) 1989-08-23
FI91638C (fi) 1994-07-25
CA1325807C (en) 1994-01-04
ATE104981T1 (de) 1994-05-15
MX9203809A (es) 1992-07-01
IE62754B1 (en) 1995-02-22
US4977158A (en) 1990-12-11
AU618392B2 (en) 1991-12-19
JPH02111776A (ja) 1990-04-24

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