ATE104981T1 - Tetracyclische antidepressiva. - Google Patents
Tetracyclische antidepressiva.Info
- Publication number
- ATE104981T1 ATE104981T1 AT8989202105T AT89202105T ATE104981T1 AT E104981 T1 ATE104981 T1 AT E104981T1 AT 8989202105 T AT8989202105 T AT 8989202105T AT 89202105 T AT89202105 T AT 89202105T AT E104981 T1 ATE104981 T1 AT E104981T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- different substituents
- substituents
- tetracyclic antidepressants
- neuroleptic
- Prior art date
Links
- 239000000935 antidepressant agent Substances 0.000 title abstract 2
- 229940005513 antidepressants Drugs 0.000 title 1
- 125000001424 substituent group Chemical group 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 239000003176 neuroleptic agent Substances 0.000 abstract 1
- 230000000701 neuroleptic effect Effects 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8802109 | 1988-08-26 | ||
| EP89202105A EP0357126B1 (de) | 1988-08-26 | 1989-08-17 | Tetracyclische Antidepressiva |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE104981T1 true ATE104981T1 (de) | 1994-05-15 |
Family
ID=19852805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT8989202105T ATE104981T1 (de) | 1988-08-26 | 1989-08-17 | Tetracyclische antidepressiva. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4977158A (de) |
| EP (1) | EP0357126B1 (de) |
| JP (1) | JP2521157B2 (de) |
| KR (1) | KR900003177A (de) |
| AT (1) | ATE104981T1 (de) |
| AU (1) | AU618392B2 (de) |
| CA (1) | CA1325807C (de) |
| DE (1) | DE68914917T2 (de) |
| DK (1) | DK415789A (de) |
| ES (1) | ES2056194T3 (de) |
| FI (1) | FI91638C (de) |
| IE (1) | IE62754B1 (de) |
| MX (1) | MX9203809A (de) |
| NZ (1) | NZ230128A (de) |
| PT (1) | PT91555B (de) |
| ZA (1) | ZA895623B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE59607332D1 (de) * | 1995-02-08 | 2001-08-30 | Novartis Ag | Antineurodegenerativ wirksame 10-Aminoaliphatyl-dibenz- b,f oxepine |
| AU2418499A (en) * | 1997-12-19 | 1999-07-12 | Akzo Nobel N.V. | Org-5222 in the treatment of depression |
| HRP20020305A8 (en) | 2002-04-10 | 2009-03-31 | GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. | 2-thia-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof |
| HRP20020440B1 (en) | 2002-05-21 | 2008-02-29 | GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. | 1-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof |
| HRP20020452A2 (en) | 2002-05-23 | 2004-02-29 | Pliva D D | 1,2-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediates for preparation thereof |
| HRP20030956A2 (en) * | 2003-11-21 | 2005-08-31 | Pliva-Istra�iva�ki institut d.o.o. | USE OF 1,2-DIAZA-DIBENZO[e,h]AZULENES FOR THE MANU |
| JP5245428B2 (ja) * | 2007-07-06 | 2013-07-24 | 住友化学株式会社 | トランス−ジベンゾオキセノピロール化合物の製造方法およびその中間体 |
| US20090233958A1 (en) * | 2008-02-19 | 2009-09-17 | Adolor Corporation | (+)-beloxepin and methods for its synthesis and use |
| CA2715192A1 (en) | 2008-02-19 | 2009-08-27 | Adolor Corporation | Beloxepin, its enantiomers, and analogs thereof for the treatment of pain |
| US20090233957A1 (en) * | 2008-02-19 | 2009-09-17 | Adolor Corporation | (-)-beloxepin and methods for its synthesis and use |
| US20090233959A1 (en) * | 2008-02-19 | 2009-09-17 | Adolor Corporation | Beloxepin and analogs for the treatment of pain |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7605526A (nl) * | 1976-05-24 | 1977-11-28 | Akzo Nv | Nieuwe tetracyclische derivaten. |
| US4271177A (en) * | 1976-05-24 | 1981-06-02 | Akzona Incorporated | 2,3,3a,12b-Tetrahydro-1H-dibenzo[2,3;6,7]thiepino[4,5-c]pyrroles and pharmaceutical use thereof |
| US4271179A (en) * | 1976-05-24 | 1981-06-02 | Akzona Incorporated | 1,2,3,3a,8,12b-Hexahydro-dibenzo[1,2;5,6]cyclohepta[3,4-C]pyrroles and pharmaceutical use thereof |
| US4158059A (en) * | 1976-05-24 | 1979-06-12 | Akzona Incorporated | Tension reducing 2,3,4,4a,9,136-hexahydro-dibenz[1,2;5,6]cyclohepta[3,4-c]py |
| AU604726B2 (en) * | 1986-06-26 | 1991-01-03 | Kyowa Hakko Kogyo Co. Ltd. | Antiarrhythmic agent |
-
1989
- 1989-07-20 IE IE236389A patent/IE62754B1/en not_active IP Right Cessation
- 1989-07-24 ZA ZA895623A patent/ZA895623B/xx unknown
- 1989-07-28 NZ NZ230128A patent/NZ230128A/xx unknown
- 1989-08-15 CA CA000608326A patent/CA1325807C/en not_active Expired - Fee Related
- 1989-08-17 ES ES89202105T patent/ES2056194T3/es not_active Expired - Lifetime
- 1989-08-17 DE DE68914917T patent/DE68914917T2/de not_active Expired - Fee Related
- 1989-08-17 EP EP89202105A patent/EP0357126B1/de not_active Expired - Lifetime
- 1989-08-17 AT AT8989202105T patent/ATE104981T1/de active
- 1989-08-18 AU AU40022/89A patent/AU618392B2/en not_active Ceased
- 1989-08-18 FI FI893901A patent/FI91638C/fi not_active IP Right Cessation
- 1989-08-23 US US07/397,228 patent/US4977158A/en not_active Expired - Fee Related
- 1989-08-23 DK DK415789A patent/DK415789A/da not_active Application Discontinuation
- 1989-08-25 PT PT91555A patent/PT91555B/pt not_active IP Right Cessation
- 1989-08-25 JP JP1220140A patent/JP2521157B2/ja not_active Expired - Lifetime
- 1989-08-25 KR KR1019890012102A patent/KR900003177A/ko not_active Ceased
-
1992
- 1992-06-29 MX MX9203809A patent/MX9203809A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE68914917T2 (de) | 1994-08-11 |
| JP2521157B2 (ja) | 1996-07-31 |
| PT91555B (pt) | 1995-05-04 |
| NZ230128A (en) | 1990-10-26 |
| EP0357126B1 (de) | 1994-04-27 |
| PT91555A (pt) | 1990-03-08 |
| AU4002289A (en) | 1990-03-01 |
| DE68914917D1 (de) | 1994-06-01 |
| FI893901A0 (fi) | 1989-08-18 |
| DK415789D0 (da) | 1989-08-23 |
| FI893901L (fi) | 1990-02-27 |
| IE892363L (en) | 1990-02-26 |
| IE62754B1 (en) | 1995-02-22 |
| EP0357126A1 (de) | 1990-03-07 |
| AU618392B2 (en) | 1991-12-19 |
| DK415789A (da) | 1990-02-27 |
| MX9203809A (es) | 1992-07-01 |
| CA1325807C (en) | 1994-01-04 |
| ZA895623B (en) | 1990-05-30 |
| US4977158A (en) | 1990-12-11 |
| FI91638C (fi) | 1994-07-25 |
| KR900003177A (ko) | 1990-03-23 |
| JPH02111776A (ja) | 1990-04-24 |
| FI91638B (fi) | 1994-04-15 |
| ES2056194T3 (es) | 1994-10-01 |
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