DK0869816T3 - Törre sammensætninger omfattende hydrofobe stabilisatorer - Google Patents
Törre sammensætninger omfattende hydrofobe stabilisatorerInfo
- Publication number
- DK0869816T3 DK0869816T3 DK96942636T DK96942636T DK0869816T3 DK 0869816 T3 DK0869816 T3 DK 0869816T3 DK 96942636 T DK96942636 T DK 96942636T DK 96942636 T DK96942636 T DK 96942636T DK 0869816 T3 DK0869816 T3 DK 0869816T3
- Authority
- DK
- Denmark
- Prior art keywords
- dry compositions
- hydrophobic stabilizers
- stabilizers
- hydrophobic
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33671495 | 1995-12-25 | ||
| EP96942636A EP0869816B1 (en) | 1995-12-25 | 1996-12-25 | Dry compositions comprising hydrophobic stabilizers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0869816T3 true DK0869816T3 (da) | 2005-01-31 |
Family
ID=18302038
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04002580T DK1424066T3 (da) | 1995-12-25 | 1996-12-25 | Törre sammensætninger omfattende hydrofobe stabilisatorer |
| DK96942636T DK0869816T3 (da) | 1995-12-25 | 1996-12-25 | Törre sammensætninger omfattende hydrofobe stabilisatorer |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04002580T DK1424066T3 (da) | 1995-12-25 | 1996-12-25 | Törre sammensætninger omfattende hydrofobe stabilisatorer |
Country Status (16)
| Country | Link |
|---|---|
| EP (2) | EP1424066B1 (da) |
| JP (2) | JP3208441B2 (da) |
| KR (1) | KR100461291B1 (da) |
| CN (1) | CN101279095A (da) |
| AR (1) | AR005274A1 (da) |
| AT (2) | ATE284713T1 (da) |
| AU (1) | AU705094B2 (da) |
| BR (1) | BR9612236A (da) |
| CA (1) | CA2241179C (da) |
| DE (2) | DE69634046T2 (da) |
| DK (2) | DK1424066T3 (da) |
| ES (2) | ES2233983T3 (da) |
| MX (1) | MX9805196A (da) |
| PT (2) | PT869816E (da) |
| TW (1) | TW403653B (da) |
| WO (1) | WO1997023239A1 (da) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| ATE416790T1 (de) | 1998-06-26 | 2008-12-15 | Otsuka Pharma Co Ltd | Wasserlösliche trockene zusammensetzungen |
| NZ518401A (en) | 1999-10-29 | 2004-01-30 | Nektar Therapeutics | Dry powder compositions having improved dispersivity |
| ATE358171T1 (de) * | 1999-12-24 | 2007-04-15 | Otsuka Pharma Co Ltd | Hydrophobe aminosäuren enthaltende trockene zusammensetzung |
| EP1304106A4 (en) | 2000-07-24 | 2005-01-19 | Ono Pharmaceutical Co | FREEZING PREPARATION OF N-o- (p-PIVALOYLOXYBENZENESULFONYLAMINO) BENZOYL] GLYCIN MONOSODIUM SALT TETRAHYDRATE AND PROCESS FOR THE PRODUCTION THEREOF |
| WO2002053136A1 (fr) * | 2000-12-28 | 2002-07-11 | Takeda Chemical Industries, Ltd. | Preparations a liberation soutenue |
| AR034489A1 (es) * | 2001-06-15 | 2004-02-25 | Otsuka Pharma Co Ltd | Un sistema de inhalacion de polvo seco para la administracion transpulmonar. |
| EG24184A (en) | 2001-06-15 | 2008-10-08 | Otsuka Pharma Co Ltd | Dry powder inhalation system for transpulmonary |
| DE60329744D1 (de) | 2002-02-22 | 2009-12-03 | Ajinomoto Kk | Aminosäurepulver und verfahren zu seiner herstellung |
| WO2004028557A1 (ja) * | 2002-09-26 | 2004-04-08 | Shionogi & Co., Ltd. | 安定化されたタンパク組成物 |
| DK1575531T3 (da) * | 2002-09-27 | 2011-11-21 | Biogen Idec Inc | Terapier for kronisk inflammatorisk demyeliniserende polyneuropati under anvendelse af interferon-beta |
| DE102004022927A1 (de) * | 2004-05-10 | 2005-12-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 1,4 O-verknüpfte Saccharose-Derivate zur Stabilisierung von Antikörpern oder Antikörper-Derivaten |
| EP1839502A4 (en) * | 2004-12-07 | 2010-03-24 | Ajinomoto Kk | FINE AMINO ACID POWDER AND SUSPENSION THEREOF |
| MY139088A (en) * | 2005-02-21 | 2009-08-28 | Lg Life Sciences Ltd | Sustained release composition of protein drug |
| WO2007013677A1 (ja) * | 2005-07-27 | 2007-02-01 | Ajinomoto Co., Inc. | インターフェロン作用物質の活性増強剤 |
| CA2690164A1 (en) * | 2007-06-16 | 2008-12-24 | Enigma Diagnostics Limited | Compositions |
| MX2020009878A (es) * | 2013-07-18 | 2022-07-27 | Mannkind Corp | Composiciones farmaceuticas en polvo seco estables al calor y metodos. |
| CN104472877B (zh) * | 2014-12-17 | 2017-07-18 | 宁夏伊品生物科技股份有限公司 | L‑赖氨酸制品的制备工艺 |
| WO2018113891A1 (en) * | 2016-12-23 | 2018-06-28 | University Of Copenhagen | A co-amorphous form of a substance and a dipeptide |
| JP7149630B2 (ja) | 2021-01-14 | 2022-10-07 | 株式会社G.A.Yellows | 樹脂リム一体型金属眼鏡フレーム |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0341033A (ja) * | 1989-07-07 | 1991-02-21 | Kyowa Hakko Kogyo Co Ltd | 安定なモチリン類含有製剤 |
| WO1992017209A1 (en) * | 1991-04-08 | 1992-10-15 | Sumitomo Pharmaceuticals Company, Limited | Porous solid preparation containing physiologically active protein substance |
| US6582728B1 (en) * | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| ES2245780T3 (es) * | 1994-05-18 | 2006-01-16 | Nektar Therapeutics | Metodos y composiciones para la formulacion de interferones como un polvo seco. |
| US6117455A (en) * | 1994-09-30 | 2000-09-12 | Takeda Chemical Industries, Ltd. | Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent |
-
1996
- 1996-12-24 TW TW085116021A patent/TW403653B/zh not_active IP Right Cessation
- 1996-12-25 AU AU11732/97A patent/AU705094B2/en not_active Ceased
- 1996-12-25 CA CA2241179A patent/CA2241179C/en not_active Expired - Fee Related
- 1996-12-25 BR BR9612236A patent/BR9612236A/pt not_active IP Right Cessation
- 1996-12-25 DE DE69634046T patent/DE69634046T2/de not_active Expired - Lifetime
- 1996-12-25 AT AT96942636T patent/ATE284713T1/de active
- 1996-12-25 EP EP04002580A patent/EP1424066B1/en not_active Expired - Lifetime
- 1996-12-25 PT PT96942636T patent/PT869816E/pt unknown
- 1996-12-25 CN CNA2008100870983A patent/CN101279095A/zh active Pending
- 1996-12-25 KR KR10-1998-0704875A patent/KR100461291B1/ko not_active IP Right Cessation
- 1996-12-25 ES ES96942636T patent/ES2233983T3/es not_active Expired - Lifetime
- 1996-12-25 DE DE69637450T patent/DE69637450T2/de not_active Expired - Lifetime
- 1996-12-25 JP JP34505496A patent/JP3208441B2/ja not_active Expired - Fee Related
- 1996-12-25 WO PCT/JP1996/003772 patent/WO1997023239A1/en active IP Right Grant
- 1996-12-25 DK DK04002580T patent/DK1424066T3/da active
- 1996-12-25 ES ES04002580T patent/ES2300667T3/es not_active Expired - Lifetime
- 1996-12-25 EP EP96942636A patent/EP0869816B1/en not_active Expired - Lifetime
- 1996-12-25 AT AT04002580T patent/ATE387188T1/de active
- 1996-12-25 DK DK96942636T patent/DK0869816T3/da active
- 1996-12-25 PT PT04002580T patent/PT1424066E/pt unknown
- 1996-12-26 AR ARP960105889A patent/AR005274A1/es active IP Right Grant
-
1998
- 1998-06-25 MX MX9805196A patent/MX9805196A/es not_active IP Right Cessation
-
2000
- 2000-12-27 JP JP2000398486A patent/JP4099623B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69634046T2 (de) | 2005-12-22 |
| DK1424066T3 (da) | 2008-05-26 |
| EP1424066A1 (en) | 2004-06-02 |
| EP0869816B1 (en) | 2004-12-15 |
| DE69637450D1 (de) | 2008-04-10 |
| EP0869816A1 (en) | 1998-10-14 |
| CA2241179C (en) | 2010-10-19 |
| PT869816E (pt) | 2005-03-31 |
| TW403653B (en) | 2000-09-01 |
| AU1173297A (en) | 1997-07-17 |
| JP2001172198A (ja) | 2001-06-26 |
| KR100461291B1 (ko) | 2005-02-28 |
| AU705094B2 (en) | 1999-05-13 |
| BR9612236A (pt) | 1999-07-13 |
| ES2233983T3 (es) | 2005-06-16 |
| ATE284713T1 (de) | 2005-01-15 |
| JP4099623B2 (ja) | 2008-06-11 |
| ATE387188T1 (de) | 2008-03-15 |
| CN101279095A (zh) | 2008-10-08 |
| JPH09235238A (ja) | 1997-09-09 |
| KR19990076752A (ko) | 1999-10-15 |
| WO1997023239A1 (en) | 1997-07-03 |
| CA2241179A1 (en) | 1997-07-03 |
| PT1424066E (pt) | 2008-04-23 |
| ES2300667T3 (es) | 2008-06-16 |
| AR005274A1 (es) | 1999-04-28 |
| JP3208441B2 (ja) | 2001-09-10 |
| DE69634046D1 (de) | 2005-01-20 |
| DE69637450T2 (de) | 2009-02-19 |
| MX9805196A (es) | 1998-10-31 |
| EP1424066B1 (en) | 2008-02-27 |
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