DK0861248T3 - Indolalkylderivater af benzodioxanmethylamin som 5-HT1A receptorligander - Google Patents
Indolalkylderivater af benzodioxanmethylamin som 5-HT1A receptorliganderInfo
- Publication number
- DK0861248T3 DK0861248T3 DK96937782T DK96937782T DK0861248T3 DK 0861248 T3 DK0861248 T3 DK 0861248T3 DK 96937782 T DK96937782 T DK 96937782T DK 96937782 T DK96937782 T DK 96937782T DK 0861248 T3 DK0861248 T3 DK 0861248T3
- Authority
- DK
- Denmark
- Prior art keywords
- benzodioxane
- methylamine
- receptor ligands
- alkyl derivatives
- ht1a receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US728495P | 1995-11-06 | 1995-11-06 | |
| PCT/US1996/017275 WO1997017343A1 (en) | 1995-11-06 | 1996-10-29 | Indolealkyl derivatives of benzodioxanmethylamine as 5-ht1a receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0861248T3 true DK0861248T3 (da) | 2002-04-08 |
Family
ID=21725271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96937782T DK0861248T3 (da) | 1995-11-06 | 1996-10-29 | Indolalkylderivater af benzodioxanmethylamin som 5-HT1A receptorligander |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5750724A (hu) |
| EP (1) | EP0861248B1 (hu) |
| JP (1) | JP2000500136A (hu) |
| KR (1) | KR19990067303A (hu) |
| CN (1) | CN1074414C (hu) |
| AR (1) | AR004229A1 (hu) |
| AT (1) | ATE210659T1 (hu) |
| BR (1) | BR9611406A (hu) |
| CA (1) | CA2236678A1 (hu) |
| DE (1) | DE69617995T2 (hu) |
| DK (1) | DK0861248T3 (hu) |
| ES (1) | ES2166470T3 (hu) |
| HK (1) | HK1015366A1 (hu) |
| HU (1) | HUP9902091A3 (hu) |
| IL (1) | IL124095A (hu) |
| MX (1) | MX9803455A (hu) |
| NZ (1) | NZ321821A (hu) |
| PT (1) | PT861248E (hu) |
| TW (1) | TW498075B (hu) |
| WO (1) | WO1997017343A1 (hu) |
| ZA (1) | ZA969221B (hu) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6231833B1 (en) | 1999-08-05 | 2001-05-15 | Pfizer Inc | 2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors |
| US6121307A (en) | 1998-04-08 | 2000-09-19 | American Home Products Corp. | N-aryloxyethyl-indoly-alkylamines for the treatment of depression |
| CA2373855A1 (en) * | 1999-05-12 | 2000-11-23 | Solvay Pharmaceuticals B.V. | Method of treating psychotic disorders |
| SI1212320T1 (en) | 1999-08-23 | 2005-10-31 | Solvay Pharmaceuticals B.V. | Phenylpiperazines as serotonin reuptake inhibitors |
| FR2799463B1 (fr) * | 1999-10-12 | 2004-04-16 | Adir | Nouveaux composes cyano-indoles inhibiteurs de recapture de serotonine, leur procede de preparation et ces compositions pharmaceutiques qui les contiennent |
| AR032712A1 (es) | 2001-02-21 | 2003-11-19 | Solvay Pharm Bv | Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen |
| US6559169B2 (en) | 2001-04-24 | 2003-05-06 | Wyeth | Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-benzodioxan |
| US7041683B2 (en) * | 2001-04-24 | 2006-05-09 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1, 4-benzodiozan |
| US6656951B2 (en) * | 2001-04-24 | 2003-12-02 | Wyeth | 8-aza-bicyclo[3.2.1]octan-3-ol derivatives of 2,3-dihydro-1,4-benzodioxan as 5-HT1A antagonists |
| US6656950B2 (en) | 2001-04-25 | 2003-12-02 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine |
| US8106074B2 (en) | 2001-07-13 | 2012-01-31 | Pierre Fabre Medicament | Pyridin-2-yl-methylamine derivatives for treating opiate dependence |
| US6667322B2 (en) | 2001-10-05 | 2003-12-23 | Wyeth | Antidepressant chroman and chromene derivatives of 3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole |
| US6911445B2 (en) * | 2002-09-12 | 2005-06-28 | Wyeth | Antidepressant cycloalkylamine derivatives of heterocycle-fused benzodioxans |
| US6800637B2 (en) * | 2002-09-12 | 2004-10-05 | Wyeth | Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines |
| US7227023B2 (en) * | 2003-04-30 | 2007-06-05 | Wyeth | Quinoline 3-amino chroman derivatives |
| CA2597616A1 (en) | 2005-02-17 | 2006-08-24 | Wyeth | Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives |
| MX2010011498A (es) | 2008-04-29 | 2010-11-12 | Nsab Af Neurosearch Sweden Ab | Moduladores de neurotransmision de dopamina. |
| JP2011519839A (ja) * | 2008-04-29 | 2011-07-14 | エヌエスエイビー、フィリアル アヴ ノイロサーチ スウェーデン エービー、スヴェーリエ | ドーパミン神経伝達のモジュレーター |
| MX2010011724A (es) | 2008-04-29 | 2010-11-30 | Nsab Af Neurosearch Sweden Ab | Moduladores de neurotransmision de dopamina. |
| CN103965186B (zh) * | 2013-01-25 | 2016-05-18 | 江苏恩华药业股份有限公司 | 苯并二噁烷-苯并噁（噻）唑哌啶衍生物及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1054104A (hu) * | 1962-07-20 | |||
| JPS58219114A (ja) * | 1982-06-15 | 1983-12-20 | Mitsubishi Chem Ind Ltd | 血圧降下剤 |
| DE3419935A1 (de) * | 1984-05-28 | 1985-11-28 | Merck Patent Gmbh, 6100 Darmstadt | Verwendung von hydroxyindolderivaten bei der senkung des blutdrucks |
| US4910302A (en) * | 1988-12-19 | 1990-03-20 | American Home Products Corporation | Psychotropic polycyclic imides |
| CA2043709C (en) * | 1990-06-29 | 2002-01-22 | David W. Smith | Antimigraine alkoxypyrimidine derivatives |
| DE4101686A1 (de) * | 1991-01-22 | 1992-07-23 | Merck Patent Gmbh | Indolderivate |
| FR2707294B1 (fr) * | 1993-07-06 | 1995-09-29 | Pf Medicament | Nouveaux dérivés de la 3,5-dioxo-(2H,4H)-1,2,4-triazine, leur préparation et leur application en thérapeutique humaine. |
| DE19512639A1 (de) * | 1995-04-05 | 1996-10-10 | Merck Patent Gmbh | Benzonitrile und -fluoride |
-
1996
- 1996-10-24 AR ARP960104894A patent/AR004229A1/es active IP Right Grant
- 1996-10-29 BR BR9611406A patent/BR9611406A/pt not_active Application Discontinuation
- 1996-10-29 WO PCT/US1996/017275 patent/WO1997017343A1/en active IP Right Grant
- 1996-10-29 PT PT96937782T patent/PT861248E/pt unknown
- 1996-10-29 CN CN96199286A patent/CN1074414C/zh not_active Expired - Fee Related
- 1996-10-29 KR KR1019980703286A patent/KR19990067303A/ko active IP Right Grant
- 1996-10-29 HU HU9902091A patent/HUP9902091A3/hu unknown
- 1996-10-29 DE DE69617995T patent/DE69617995T2/de not_active Expired - Fee Related
- 1996-10-29 CA CA002236678A patent/CA2236678A1/en not_active Abandoned
- 1996-10-29 ES ES96937782T patent/ES2166470T3/es not_active Expired - Lifetime
- 1996-10-29 JP JP9518222A patent/JP2000500136A/ja not_active Withdrawn
- 1996-10-29 IL IL12409596A patent/IL124095A/en not_active IP Right Cessation
- 1996-10-29 AT AT96937782T patent/ATE210659T1/de not_active IP Right Cessation
- 1996-10-29 EP EP96937782A patent/EP0861248B1/en not_active Expired - Lifetime
- 1996-10-29 DK DK96937782T patent/DK0861248T3/da active
- 1996-10-29 NZ NZ321821A patent/NZ321821A/xx unknown
- 1996-10-30 US US08/739,912 patent/US5750724A/en not_active Expired - Lifetime
- 1996-11-01 ZA ZA9609221A patent/ZA969221B/xx unknown
- 1996-11-05 TW TW085113500A patent/TW498075B/zh active
-
1998
- 1998-04-30 MX MX9803455A patent/MX9803455A/es not_active IP Right Cessation
-
1999
- 1999-02-02 HK HK99100444A patent/HK1015366A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| TW498075B (en) | 2002-08-11 |
| AU7524596A (en) | 1997-05-29 |
| KR19990067303A (ko) | 1999-08-16 |
| HUP9902091A2 (hu) | 2000-02-28 |
| ZA969221B (en) | 1998-05-04 |
| JP2000500136A (ja) | 2000-01-11 |
| HUP9902091A3 (en) | 2000-03-28 |
| NZ321821A (en) | 1999-07-29 |
| CN1205700A (zh) | 1999-01-20 |
| EP0861248B1 (en) | 2001-12-12 |
| WO1997017343A1 (en) | 1997-05-15 |
| CA2236678A1 (en) | 1997-05-15 |
| DE69617995T2 (de) | 2002-05-16 |
| MX9803455A (es) | 1998-09-30 |
| ATE210659T1 (de) | 2001-12-15 |
| AU704216B2 (en) | 1999-04-15 |
| EP0861248A1 (en) | 1998-09-02 |
| PT861248E (pt) | 2002-05-31 |
| US5750724A (en) | 1998-05-12 |
| HK1015366A1 (en) | 1999-10-15 |
| ES2166470T3 (es) | 2002-04-16 |
| AR004229A1 (es) | 1998-11-04 |
| IL124095A (en) | 2001-10-31 |
| DE69617995D1 (de) | 2002-01-24 |
| CN1074414C (zh) | 2001-11-07 |
| BR9611406A (pt) | 1999-01-05 |
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