BR9611406A - Derivados de indolalquila da benzodioxano metilamina como ligantes dos receptores de 5-HT1A - Google Patents

Derivados de indolalquila da benzodioxano metilamina como ligantes dos receptores de 5-HT1A

Info

Publication number
BR9611406A
BR9611406A BR9611406A BR9611406A BR9611406A BR 9611406 A BR9611406 A BR 9611406A BR 9611406 A BR9611406 A BR 9611406A BR 9611406 A BR9611406 A BR 9611406A BR 9611406 A BR9611406 A BR 9611406A
Authority
BR
Brazil
Prior art keywords
indolalkyl
benzodioxane
methylamine
ligands
derivatives
Prior art date
Application number
BR9611406A
Other languages
English (en)
Inventor
Young Hee Kang
Gary Paul Stack
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of BR9611406A publication Critical patent/BR9611406A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
BR9611406A 1995-11-06 1996-10-29 Derivados de indolalquila da benzodioxano metilamina como ligantes dos receptores de 5-HT1A BR9611406A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US728495P 1995-11-06 1995-11-06
PCT/US1996/017275 WO1997017343A1 (en) 1995-11-06 1996-10-29 Indolealkyl derivatives of benzodioxanmethylamine as 5-ht1a receptor ligands

Publications (1)

Publication Number Publication Date
BR9611406A true BR9611406A (pt) 1999-01-05

Family

ID=21725271

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9611406A BR9611406A (pt) 1995-11-06 1996-10-29 Derivados de indolalquila da benzodioxano metilamina como ligantes dos receptores de 5-HT1A

Country Status (21)

Country Link
US (1) US5750724A (pt)
EP (1) EP0861248B1 (pt)
JP (1) JP2000500136A (pt)
KR (1) KR19990067303A (pt)
CN (1) CN1074414C (pt)
AR (1) AR004229A1 (pt)
AT (1) ATE210659T1 (pt)
BR (1) BR9611406A (pt)
CA (1) CA2236678A1 (pt)
DE (1) DE69617995T2 (pt)
DK (1) DK0861248T3 (pt)
ES (1) ES2166470T3 (pt)
HK (1) HK1015366A1 (pt)
HU (1) HUP9902091A3 (pt)
IL (1) IL124095A (pt)
MX (1) MX9803455A (pt)
NZ (1) NZ321821A (pt)
PT (1) PT861248E (pt)
TW (1) TW498075B (pt)
WO (1) WO1997017343A1 (pt)
ZA (1) ZA969221B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6231833B1 (en) 1999-08-05 2001-05-15 Pfizer Inc 2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors
US6121307A (en) 1998-04-08 2000-09-19 American Home Products Corp. N-aryloxyethyl-indoly-alkylamines for the treatment of depression
WO2000069424A2 (en) * 1999-05-12 2000-11-23 Solvay Pharmaceuticals B.V. Method of treating psychotic disorders
TR200200460T2 (tr) 1999-08-23 2002-06-21 Solvay Pharmaceuticals B.V. Yeni fenilpiperazinler
FR2799463B1 (fr) * 1999-10-12 2004-04-16 Adir Nouveaux composes cyano-indoles inhibiteurs de recapture de serotonine, leur procede de preparation et ces compositions pharmaceutiques qui les contiennent
AR032712A1 (es) 2001-02-21 2003-11-19 Solvay Pharm Bv Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen
AU2002258971A1 (en) 2001-04-24 2002-11-05 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-benzodioxan
US7041683B2 (en) * 2001-04-24 2006-05-09 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1, 4-benzodiozan
US6656951B2 (en) 2001-04-24 2003-12-02 Wyeth 8-aza-bicyclo[3.2.1]octan-3-ol derivatives of 2,3-dihydro-1,4-benzodioxan as 5-HT1A antagonists
US6656950B2 (en) 2001-04-25 2003-12-02 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine
US8106074B2 (en) 2001-07-13 2012-01-31 Pierre Fabre Medicament Pyridin-2-yl-methylamine derivatives for treating opiate dependence
US6667322B2 (en) 2001-10-05 2003-12-23 Wyeth Antidepressant chroman and chromene derivatives of 3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole
US6800637B2 (en) * 2002-09-12 2004-10-05 Wyeth Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines
US6911445B2 (en) 2002-09-12 2005-06-28 Wyeth Antidepressant cycloalkylamine derivatives of heterocycle-fused benzodioxans
US7227023B2 (en) * 2003-04-30 2007-06-05 Wyeth Quinoline 3-amino chroman derivatives
BRPI0608353A2 (pt) * 2005-02-17 2009-12-01 Wyeth Corp derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilfundidos
DK2271634T3 (da) 2008-04-29 2014-05-05 Integrative Res Lab Sweden Ab Modulatorer af dopamin-neurotransmission
US20110105462A1 (en) * 2008-04-29 2011-05-05 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Modulators of dopamine neurotransmission
EP2271638B1 (en) 2008-04-29 2011-08-31 NSAB, Filial af NeuroSearch Sweden AB, Sverige Modulators of dopamine neurotransmission
CN103965186B (zh) * 2013-01-25 2016-05-18 江苏恩华药业股份有限公司 苯并二噁烷-苯并噁（噻）唑哌啶衍生物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE635203A (pt) * 1962-07-20
JPS58219114A (ja) * 1982-06-15 1983-12-20 Mitsubishi Chem Ind Ltd 血圧降下剤
DE3419935A1 (de) * 1984-05-28 1985-11-28 Merck Patent Gmbh, 6100 Darmstadt Verwendung von hydroxyindolderivaten bei der senkung des blutdrucks
US4910302A (en) * 1988-12-19 1990-03-20 American Home Products Corporation Psychotropic polycyclic imides
CA2043709C (en) * 1990-06-29 2002-01-22 David W. Smith Antimigraine alkoxypyrimidine derivatives
DE4101686A1 (de) * 1991-01-22 1992-07-23 Merck Patent Gmbh Indolderivate
FR2707294B1 (fr) * 1993-07-06 1995-09-29 Pf Medicament Nouveaux dérivés de la 3,5-dioxo-(2H,4H)-1,2,4-triazine, leur préparation et leur application en thérapeutique humaine.
DE19512639A1 (de) * 1995-04-05 1996-10-10 Merck Patent Gmbh Benzonitrile und -fluoride

Also Published As

Publication number Publication date
TW498075B (en) 2002-08-11
AU7524596A (en) 1997-05-29
NZ321821A (en) 1999-07-29
CN1205700A (zh) 1999-01-20
KR19990067303A (ko) 1999-08-16
ZA969221B (en) 1998-05-04
CA2236678A1 (en) 1997-05-15
IL124095A (en) 2001-10-31
CN1074414C (zh) 2001-11-07
DK0861248T3 (da) 2002-04-08
AU704216B2 (en) 1999-04-15
JP2000500136A (ja) 2000-01-11
AR004229A1 (es) 1998-11-04
HK1015366A1 (en) 1999-10-15
WO1997017343A1 (en) 1997-05-15
PT861248E (pt) 2002-05-31
EP0861248B1 (en) 2001-12-12
DE69617995D1 (de) 2002-01-24
HUP9902091A3 (en) 2000-03-28
DE69617995T2 (de) 2002-05-16
HUP9902091A2 (hu) 2000-02-28
US5750724A (en) 1998-05-12
ES2166470T3 (es) 2002-04-16
ATE210659T1 (de) 2001-12-15
EP0861248A1 (en) 1998-09-02
MX9803455A (es) 1998-09-30

Similar Documents

Publication Publication Date Title
BR9611406A (pt) Derivados de indolalquila da benzodioxano metilamina como ligantes dos receptores de 5-HT1A
MA23815A1 (fr) Derives de n-(3-benzofuranyl)-uree
EE9800227A (et) 17ß-karboksü-, karbotio- ja amiidandrostaanide laktoonderivaadid
BR9709220A (pt) Derivados de tetra-hidro-isoquinolina como moduladores dos receptores D3 da dopamina
BR9609260A (pt) Derivados de rapamicina
FR09C0065I2 (fr) Derives de quinazoline
PT823889E (pt) Derivados de 1,3-propanodiol como compostos bioactivos
ATE226212T1 (de) 2-(purin-9-)-tetrahydrofuran-3,4-diol-derivate
BR9611834A (pt) Derivados de oximetóxi-3-aril-pirona
DE69612852D1 (de) BENZO[g]CHINOLINDERIVATE
PT891362E (pt) Derivados de pirrolopirrolona como inibidores da elastase dos neutrofilos
BR9605434A (pt) Derivados de purin-6-ona
EE200000140A (et) Asendatud kromaani derivaadid
PT747385E (pt) Pro-farmacos de derivados de paclitaxel
EE200000144A (et) Asendatud kromaani derivaadid
BR9609694A (pt) Derivados de peperazina e uso dos mesmos como antagonistas a 5-ht1a
PT854867E (pt) Tetra-hidroquinolinas como antagonistas de nmda
ATE224891T1 (de) Chromon-derivate
PT856007E (pt) Derivados de ciclopeptidos
ITMI951900A0 (it) Derivati idroisochinolinici sostituiti
BR9610597A (pt) Derivados de diarilalcenilamina
PT1140890E (pt) Derivados de cromano
BR9507892A (pt) Novos derivados de diamino-metilideno
BR9706239B1 (pt) 3-(1-hidroxifenil-1-alcoxiiminometil) dioxazinas bem como processos de preparação dos mesmos.
MA26480A1 (fr) Derives de phenoxymethylpiperidine

Legal Events

Date Code Title Description
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
B25D Requested change of name of applicant approved

Owner name: WYETH (US)

Free format text: ALTERADO DE: AMERICAN HOMES PRODUCTS CORPORATION

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE DE ACORDO COM O ARTIGO 8 DA LPI.