DK0846689T3 - Benzimidazolforbindelser - Google Patents
BenzimidazolforbindelserInfo
- Publication number
- DK0846689T3 DK0846689T3 DK97309761T DK97309761T DK0846689T3 DK 0846689 T3 DK0846689 T3 DK 0846689T3 DK 97309761 T DK97309761 T DK 97309761T DK 97309761 T DK97309761 T DK 97309761T DK 0846689 T3 DK0846689 T3 DK 0846689T3
- Authority
- DK
- Denmark
- Prior art keywords
- halo
- phenyl
- alkyl
- independently
- alkylsulfinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/10—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IB9601395 | 1996-12-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0846689T3 true DK0846689T3 (da) | 2004-04-19 |
Family
ID=11004502
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97309761T DK0846689T3 (da) | 1996-12-09 | 1997-12-03 | Benzimidazolforbindelser |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0846689B1 (de) |
JP (1) | JP3439643B2 (de) |
AT (1) | ATE257825T1 (de) |
BR (1) | BR9706241A (de) |
CA (1) | CA2223551C (de) |
DE (1) | DE69727199T2 (de) |
DK (1) | DK0846689T3 (de) |
ES (1) | ES2212054T3 (de) |
PT (1) | PT846689E (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3256513B2 (ja) | 1998-02-11 | 2002-02-12 | ファイザー製薬株式会社 | ベンゾイミダゾールシクロオキシゲナーゼ−2阻害剤 |
AU3851199A (en) | 1998-05-26 | 1999-12-13 | Chugai Seiyaku Kabushiki Kaisha | Heterocyclic indole derivatives and mono- or diazaindole derivatives |
US6291499B1 (en) * | 1999-10-29 | 2001-09-18 | Merck & Co., Inc. | 2-cyclohexyl benzimidazole NMDA/NR2B antagonists |
MY137736A (en) | 2001-04-03 | 2009-03-31 | Pharmacia Corp | Reconstitutable parenteral composition |
AR038957A1 (es) | 2001-08-15 | 2005-02-02 | Pharmacia Corp | Terapia de combinacion para el tratamiento del cancer |
EP1664032B1 (de) | 2003-08-21 | 2008-11-05 | OSI Pharmaceuticals, Inc. | N-substituierte pyrazolyl-amidyl-benzimidazolyl-c-kit-inhibitoren |
US7442709B2 (en) | 2003-08-21 | 2008-10-28 | Osi Pharmaceuticals, Inc. | N3-substituted imidazopyridine c-Kit inhibitors |
WO2005021531A1 (en) | 2003-08-21 | 2005-03-10 | Osi Pharmaceuticals, Inc. | N-substituted benzimidazolyl c-kit inhibitors |
EP1831206B1 (de) | 2004-12-01 | 2011-08-24 | OSI Pharmaceuticals, Inc. | N-substituierte benzimidazolyl-c-kit-inhibitoren und kombinatorische benzimidazolbibliothek |
ES2410905T3 (es) * | 2004-12-17 | 2013-07-03 | Merck Canada Inc. | 2-(Fenil o heterociclo)-1H-fenantro[9,10-d]imidazoles como inhibidores de la MPGES-1 |
US7442716B2 (en) * | 2004-12-17 | 2008-10-28 | Merck Frosst Canada Ltd. | 2-(phenyl or heterocyclic)-1H-phenantrho[9,10-d]imidazoles as mPGES-1 inhibitors |
EP2019675A4 (de) * | 2006-05-02 | 2011-03-02 | Merck Frosst Canada Ltd | Verfahren zur behandlung oder prävention von neoplasien |
CA3209491A1 (en) | 2021-03-15 | 2022-09-22 | Saul Yedgar | Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory disease |
CN114656418B (zh) * | 2022-04-10 | 2024-01-26 | 同济大学 | 一类(e)-苯并五元环-苯乙烯基硫鎓盐衍生物及其制备和应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH542853A (de) * | 1967-07-26 | 1973-10-15 | Agripat Sa | Verfahren zur Herstellung neuer Isothiocyano-benzazol-Derivate |
DE1962353A1 (de) * | 1969-12-12 | 1971-06-16 | Bayer Ag | Styrylaufheller |
JPS5013795B2 (de) * | 1972-12-12 | 1975-05-22 | ||
JPS5975257A (ja) * | 1982-10-23 | 1984-04-27 | Ricoh Co Ltd | 電子写真用感光体 |
JPH06759B2 (ja) * | 1989-09-22 | 1994-01-05 | ファイザー製薬株式会社 | 新規なベンゾイミダゾール化合物 |
JPH06194780A (ja) * | 1992-12-24 | 1994-07-15 | Konica Corp | ハロゲン化銀写真乳剤 |
-
1997
- 1997-12-03 DE DE1997627199 patent/DE69727199T2/de not_active Expired - Fee Related
- 1997-12-03 PT PT97309761T patent/PT846689E/pt unknown
- 1997-12-03 AT AT97309761T patent/ATE257825T1/de not_active IP Right Cessation
- 1997-12-03 DK DK97309761T patent/DK0846689T3/da active
- 1997-12-03 ES ES97309761T patent/ES2212054T3/es not_active Expired - Lifetime
- 1997-12-03 EP EP97309761A patent/EP0846689B1/de not_active Expired - Lifetime
- 1997-12-04 CA CA002223551A patent/CA2223551C/en not_active Expired - Fee Related
- 1997-12-05 JP JP35015497A patent/JP3439643B2/ja not_active Expired - Fee Related
- 1997-12-09 BR BR9706241A patent/BR9706241A/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE69727199D1 (de) | 2004-02-19 |
DE69727199T2 (de) | 2004-11-18 |
JPH10168066A (ja) | 1998-06-23 |
EP0846689A1 (de) | 1998-06-10 |
ATE257825T1 (de) | 2004-01-15 |
EP0846689B1 (de) | 2004-01-14 |
JP3439643B2 (ja) | 2003-08-25 |
CA2223551C (en) | 2004-02-10 |
PT846689E (pt) | 2004-06-30 |
CA2223551A1 (en) | 1998-06-09 |
ES2212054T3 (es) | 2004-07-16 |
BR9706241A (pt) | 1999-05-18 |
MX9710034A (es) | 1998-06-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0846689T3 (da) | Benzimidazolforbindelser | |
DK0418845T3 (da) | Pyrazolderivater, fremgangsmåder til fremstilling deraf og farmaceutisk præparat omfattende samme | |
NZ507144A (en) | Benzamide derivatives useful for the treatment of diseases mediated by cytokines | |
PH30916A (en) | Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same. | |
MY149038A (en) | Cinnamide compound | |
BR9900565A (pt) | Inibidores de ciclooxigenase-2 de benzimidazol. | |
DE69912552D1 (de) | Substituierte Indolverbindungen als COX-2 Inhibitoren | |
YU41600A (sh) | 2,3-substituisana indol jedinjenja kao cox-2 inhibitori | |
AP9901578A0 (en) | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents. | |
EP2471531A3 (de) | Nitrostyrenderivaten mit antimikrobieller Wirkung | |
DK1106614T3 (da) | 5-leddede, heteroarylsubstituerede 1,4-dihydropyridinforbindelser som bradykininantagonister | |
EP1252890A4 (de) | Heilmittel und vorbeugende mittel für verdauungserkrankungen die diaminotrifluoromethylpyridinverbindungen enthalten | |
DE69911557D1 (de) | Imidazoline Derivate,ihre Herstellung und pharmazeutische Zusammensetzungen die sie enthalten | |
MX9206930A (es) | Nuevos compuestos | |
AU2001228862A1 (en) | Remedies or preventives for liver diseases containing diaminotrifluoromethylpyridine derivatives | |
TW275629B (de) | ||
MXPA01011888A (es) | Derivados de tetrazolinona. | |
ATE158503T1 (de) | Aids-virus-infektion hemmende zusammensetzung | |
ES2102512T3 (es) | Inhibidor de la hipertrofia de vasos sanguineos. |