PT846689E - Compostos de benzimidazole - Google Patents
Compostos de benzimidazoleInfo
- Publication number
- PT846689E PT846689E PT97309761T PT97309761T PT846689E PT 846689 E PT846689 E PT 846689E PT 97309761 T PT97309761 T PT 97309761T PT 97309761 T PT97309761 T PT 97309761T PT 846689 E PT846689 E PT 846689E
- Authority
- PT
- Portugal
- Prior art keywords
- halo
- phenyl
- alkyl
- independently
- alkylsulfinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/10—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB9601395 | 1996-12-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT846689E true PT846689E (pt) | 2004-06-30 |
Family
ID=11004502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97309761T PT846689E (pt) | 1996-12-09 | 1997-12-03 | Compostos de benzimidazole |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0846689B1 (pt) |
| JP (1) | JP3439643B2 (pt) |
| AT (1) | ATE257825T1 (pt) |
| BR (1) | BR9706241A (pt) |
| CA (1) | CA2223551C (pt) |
| DE (1) | DE69727199T2 (pt) |
| DK (1) | DK0846689T3 (pt) |
| ES (1) | ES2212054T3 (pt) |
| PT (1) | PT846689E (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3256513B2 (ja) * | 1998-02-11 | 2002-02-12 | ファイザー製薬株式会社 | ベンゾイミダゾールシクロオキシゲナーゼ−２阻害剤 |
| DE69942801D1 (de) | 1998-05-26 | 2010-11-11 | Chugai Pharmaceutical Co Ltd | Heterozyklische indolderivate und mono- oder diazaindol-derivate |
| US6291499B1 (en) * | 1999-10-29 | 2001-09-18 | Merck & Co., Inc. | 2-cyclohexyl benzimidazole NMDA/NR2B antagonists |
| US7695736B2 (en) | 2001-04-03 | 2010-04-13 | Pfizer Inc. | Reconstitutable parenteral composition |
| AR038957A1 (es) | 2001-08-15 | 2005-02-02 | Pharmacia Corp | Terapia de combinacion para el tratamiento del cancer |
| US7442709B2 (en) | 2003-08-21 | 2008-10-28 | Osi Pharmaceuticals, Inc. | N3-substituted imidazopyridine c-Kit inhibitors |
| EP1664021A1 (en) | 2003-08-21 | 2006-06-07 | OSI Pharmaceuticals, Inc. | N-substituted benzimidazolyl c-kit inhibitors |
| RU2006108791A (ru) | 2003-08-21 | 2006-07-27 | Оси Фармасьютикалз, Инк. (Us) | N-замещенные пиразолиламидилбензимидазолилы в качестве с-kit ингибиторов |
| JP2008521903A (ja) | 2004-12-01 | 2008-06-26 | オーエスアイ・ファーマスーティカルズ・インコーポレーテッド | Ｎ置換されたベンズイミダゾリルＣ−ｋｉｔ阻害剤及びコンビナトリアルベンゾイミダゾールライブラリー |
| US7442716B2 (en) | 2004-12-17 | 2008-10-28 | Merck Frosst Canada Ltd. | 2-(phenyl or heterocyclic)-1H-phenantrho[9,10-d]imidazoles as mPGES-1 inhibitors |
| AU2005316091B2 (en) * | 2004-12-17 | 2011-12-01 | Merck Canada Inc. | 2-(phenyl or heterocyclic)-1H-phenantrho[9,10-D]imidazoles as mPGES-1 inhibitors |
| EP2019675A4 (en) * | 2006-05-02 | 2011-03-02 | Merck Frosst Canada Ltd | METHODS FOR TREATING OR PREVENTING NEOPLASIA |
| CA3209491A1 (en) | 2021-03-15 | 2022-09-22 | Saul Yedgar | Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory disease |
| CN114656418B (zh) * | 2022-04-10 | 2024-01-26 | 同济大学 | 一类(e)-苯并五元环-苯乙烯基硫鎓盐衍生物及其制备和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH542853A (de) * | 1967-07-26 | 1973-10-15 | Agripat Sa | Verfahren zur Herstellung neuer Isothiocyano-benzazol-Derivate |
| DE1962353A1 (de) * | 1969-12-12 | 1971-06-16 | Bayer Ag | Styrylaufheller |
| JPS5013795B2 (pt) * | 1972-12-12 | 1975-05-22 | ||
| JPS5975257A (ja) * | 1982-10-23 | 1984-04-27 | Ricoh Co Ltd | 電子写真用感光体 |
| JPH06759B2 (ja) * | 1989-09-22 | 1994-01-05 | ファイザー製薬株式会社 | 新規なベンゾイミダゾール化合物 |
| JPH06194780A (ja) * | 1992-12-24 | 1994-07-15 | Konica Corp | ハロゲン化銀写真乳剤 |
-
1997
- 1997-12-03 PT PT97309761T patent/PT846689E/pt unknown
- 1997-12-03 EP EP97309761A patent/EP0846689B1/en not_active Expired - Lifetime
- 1997-12-03 DE DE1997627199 patent/DE69727199T2/de not_active Expired - Fee Related
- 1997-12-03 ES ES97309761T patent/ES2212054T3/es not_active Expired - Lifetime
- 1997-12-03 DK DK97309761T patent/DK0846689T3/da active
- 1997-12-03 AT AT97309761T patent/ATE257825T1/de not_active IP Right Cessation
- 1997-12-04 CA CA002223551A patent/CA2223551C/en not_active Expired - Fee Related
- 1997-12-05 JP JP35015497A patent/JP3439643B2/ja not_active Expired - Fee Related
- 1997-12-09 BR BR9706241A patent/BR9706241A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10168066A (ja) | 1998-06-23 |
| CA2223551A1 (en) | 1998-06-09 |
| EP0846689A1 (en) | 1998-06-10 |
| DE69727199T2 (de) | 2004-11-18 |
| MX9710034A (es) | 1998-06-30 |
| JP3439643B2 (ja) | 2003-08-25 |
| ES2212054T3 (es) | 2004-07-16 |
| EP0846689B1 (en) | 2004-01-14 |
| DE69727199D1 (de) | 2004-02-19 |
| DK0846689T3 (da) | 2004-04-19 |
| BR9706241A (pt) | 1999-05-18 |
| CA2223551C (en) | 2004-02-10 |
| ATE257825T1 (de) | 2004-01-15 |
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