DK0806484T3 - Syntese af proteiner eller polypeptider kodet af en nucleotidsekvens af HIV-1, HIV-2 eller SIV. - Google Patents
Syntese af proteiner eller polypeptider kodet af en nucleotidsekvens af HIV-1, HIV-2 eller SIV.Info
- Publication number
- DK0806484T3 DK0806484T3 DK97110543T DK97110543T DK0806484T3 DK 0806484 T3 DK0806484 T3 DK 0806484T3 DK 97110543 T DK97110543 T DK 97110543T DK 97110543 T DK97110543 T DK 97110543T DK 0806484 T3 DK0806484 T3 DK 0806484T3
- Authority
- DK
- Denmark
- Prior art keywords
- hiv
- gene
- nucleic acid
- siv
- sequence
- Prior art date
Links
- 241000713772 Human immunodeficiency virus 1 Species 0.000 title abstract 13
- 108090000623 proteins and genes Proteins 0.000 title abstract 11
- 208000031886 HIV Infections Diseases 0.000 title abstract 7
- 241000713340 Human immunodeficiency virus 2 Species 0.000 title abstract 7
- 230000015572 biosynthetic process Effects 0.000 title abstract 4
- 239000002773 nucleotide Substances 0.000 title abstract 2
- 125000003729 nucleotide group Chemical group 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 abstract 8
- 150000007523 nucleic acids Chemical class 0.000 abstract 8
- 102000039446 nucleic acids Human genes 0.000 abstract 8
- 239000013615 primer Substances 0.000 abstract 7
- 241000700605 Viruses Species 0.000 abstract 5
- 239000012472 biological sample Substances 0.000 abstract 5
- 230000004544 DNA amplification Effects 0.000 abstract 3
- 238000004925 denaturation Methods 0.000 abstract 3
- 230000036425 denaturation Effects 0.000 abstract 3
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 2
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 2
- 230000000295 complement effect Effects 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 235000011178 triphosphate Nutrition 0.000 abstract 2
- 239000001226 triphosphate Substances 0.000 abstract 2
- UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical compound OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 abstract 2
- 108020004635 Complementary DNA Proteins 0.000 abstract 1
- 239000003155 DNA primer Substances 0.000 abstract 1
- 102100034343 Integrase Human genes 0.000 abstract 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 abstract 1
- 230000003321 amplification Effects 0.000 abstract 1
- 238000010804 cDNA synthesis Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 239000002777 nucleoside Substances 0.000 abstract 1
- 125000003835 nucleoside group Chemical group 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
- G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
- G01N2333/16—HIV-1, HIV-2
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/974—Aids related test
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- AIDS & HIV (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8907354A FR2647809B1 (fr) | 1989-06-02 | 1989-06-02 | Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus |
| FR8912371A FR2652091B1 (fr) | 1989-09-20 | 1989-09-20 | Sequences nucleotidiques issues du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications notamment pour l'amplification des genomes de ces retrovirus et pour le diagnostic in-vitro des infections dues a ces virus. |
| EP90401520A EP0403333B1 (fr) | 1989-06-02 | 1990-06-05 | Séquences nucléotidiques issues du génome des rétrovirus du typ hiv-1, et leurs applications notamment pour l'amplification des génomes de ces rétrovirus et pour le diagnostic in-vitro des infections dues à ces virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0806484T3 true DK0806484T3 (da) | 2006-08-14 |
Family
ID=26227366
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90401520T DK0403333T3 (da) | 1989-06-02 | 1990-06-05 | Nukleotidsekvenser stammende fra genomet i retrovirus af typen HIV-1, HIV-2 og SIV og deres anvendelse, fortrinsvis til opf |
| DK97110543T DK0806484T3 (da) | 1989-06-02 | 1990-06-05 | Syntese af proteiner eller polypeptider kodet af en nucleotidsekvens af HIV-1, HIV-2 eller SIV. |
| DK05014676T DK1642987T3 (da) | 1989-06-02 | 1990-06-05 | Nucleotidsekvenser dannet ud fra genomerne af retrovirusserne HIV-1, HIV-2 og SIV samt deres anvendelse til opformering af disse virale genomer samt til en vitro-diagnose af infektioner, der stammer fra disse virusser |
| DK07025195.4T DK2011888T3 (da) | 1989-06-02 | 1990-06-05 | Nukleotidsekvenser resulterende fra genomet af HIV-1-, og SIV-retroviraene og deres anvendelser til især apmplifikation af genomerne af disse retrovira og til in vitro-diagnose af infektioner forårsaget af disse vira |
| DK06013029T DK1715064T3 (da) | 1989-06-02 | 1990-06-05 | Nucleotidsekvenser fra HIV-1-, HIV-2- og SIV-retrovirusgenomer samt deres anvendelse til mangfoldiggörelse af pol-sekvenser fra disse retrovira og til diagnosticering in vitro af infektioner fremkaldt af disse vira |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90401520T DK0403333T3 (da) | 1989-06-02 | 1990-06-05 | Nukleotidsekvenser stammende fra genomet i retrovirus af typen HIV-1, HIV-2 og SIV og deres anvendelse, fortrinsvis til opf |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05014676T DK1642987T3 (da) | 1989-06-02 | 1990-06-05 | Nucleotidsekvenser dannet ud fra genomerne af retrovirusserne HIV-1, HIV-2 og SIV samt deres anvendelse til opformering af disse virale genomer samt til en vitro-diagnose af infektioner, der stammer fra disse virusser |
| DK07025195.4T DK2011888T3 (da) | 1989-06-02 | 1990-06-05 | Nukleotidsekvenser resulterende fra genomet af HIV-1-, og SIV-retroviraene og deres anvendelser til især apmplifikation af genomerne af disse retrovira og til in vitro-diagnose af infektioner forårsaget af disse vira |
| DK06013029T DK1715064T3 (da) | 1989-06-02 | 1990-06-05 | Nucleotidsekvenser fra HIV-1-, HIV-2- og SIV-retrovirusgenomer samt deres anvendelse til mangfoldiggörelse af pol-sekvenser fra disse retrovira og til diagnosticering in vitro af infektioner fremkaldt af disse vira |
Country Status (12)
| Country | Link |
|---|---|
| US (6) | US5688637A (da) |
| EP (5) | EP2011888B1 (da) |
| JP (2) | JP3428012B2 (da) |
| AT (5) | ATE423856T1 (da) |
| CA (3) | CA2062829C (da) |
| DE (7) | DE69034220T2 (da) |
| DK (5) | DK0403333T3 (da) |
| ES (5) | ES2262166T3 (da) |
| GR (1) | GR3032261T3 (da) |
| HK (3) | HK1097574A1 (da) |
| SG (1) | SG47868A1 (da) |
| WO (1) | WO1990015066A2 (da) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2262166T3 (es) * | 1989-06-02 | 2006-11-16 | Institut Pasteur | Sintesis de proteinas o polipeptidos codificados por un secuencia nucleotidica vih-1, vih-2 o siv. |
| US7022814B1 (en) | 1992-01-21 | 2006-04-04 | Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale | Nucleotide sequences derived from the genome of retroviruses of the HIV-1, HIV-2 and SIV type, and their uses in particular for the amplification of the genomes of these retroviruses and for the in vitro diagnosis of the diseases due to these viruses |
| US6589734B1 (en) | 1989-07-11 | 2003-07-08 | Gen-Probe Incorporated | Detection of HIV |
| US5856088A (en) * | 1989-07-11 | 1999-01-05 | Gen-Probe Incorporated | Detection of human immunodeficiency virus type 1 |
| JPH04152899A (ja) * | 1990-10-17 | 1992-05-26 | Shionogi & Co Ltd | ２段階ｐｃｒ法によるｈｉｖ―１ゲノムの検出法およびオリゴヌクレオチド |
| FR2677039B1 (fr) * | 1991-05-31 | 1994-09-09 | Cis Bio Int | Oligonucleotides, utilisables comme reactifs pour la detection in vitro des infections a retrovirus de type hiv et procede de detection de retrovirus de type hiv. |
| JP3907201B2 (ja) | 1991-12-23 | 2007-04-18 | カイロン コーポレイション | 溶液相サンドイッチハイブリダイゼーションアッセイに用いるためのｈｉｖプローブ |
| FR2692279B1 (fr) * | 1992-06-16 | 1995-05-19 | Centre Nat Rech Scient | Séquences nucléotidiques issues de la souche WO du vif et leurs fragments, applications desdites séquences à l'expression de peptides immunogènes et au diagnostic de l'immunodéficience féline. |
| CA2159103C (en) | 1993-03-26 | 2002-03-12 | Sherrol H. Mcdonough | Detection of human immunodeficiency virus type 1 |
| WO1995005851A1 (en) * | 1993-08-20 | 1995-03-02 | St. Luke's-Roosevelt Hospital Center | HIV vif-RELATED COMPOSITIONS, AND PROPHYLACTIC AND THERAPEUTIC USES THEREOF |
| US5733781A (en) * | 1994-07-19 | 1998-03-31 | Gen-Probe Incorporated | Oligonucleotides and methods for inhibiting propagation of human immunodeficiency virus |
| EP0877940A1 (en) | 1995-12-05 | 1998-11-18 | Donald R. Branch | Methods for the early detection of hiv infection |
| US6265152B1 (en) * | 1995-12-22 | 2001-07-24 | Visible Genetics Inc. | Method and kit for evaluation of HIV mutations |
| DE19644248A1 (de) * | 1996-10-24 | 1998-04-30 | Boehringer Mannheim Gmbh | Primer und Probes zum Nachweis von HIV |
| US6830887B2 (en) | 1997-03-18 | 2004-12-14 | Bayer Healthcare Llc | Method and kit for quantitation and nucleic acid sequencing of nucleic acid analytes in a sample |
| US5962665A (en) * | 1997-06-16 | 1999-10-05 | Abbott Laboratories | Nucleic acid primers and probes for detecting HIV-1 and HIV-2 |
| US6001558A (en) * | 1997-06-25 | 1999-12-14 | Ortho Clinical Diagnostics, Inc. | Amplification and detection of HIV-1 and/or HIV 2 |
| US6492110B1 (en) | 1998-11-02 | 2002-12-10 | Uab Research Foundation | Reference clones and sequences for non-subtype B isolates of human immunodeficiency virus type 1 |
| DE19850186A1 (de) * | 1998-10-30 | 2000-05-25 | Roche Diagnostics Gmbh | Neue Primer und Sonden zum Nachweis von HIV |
| US6303293B1 (en) * | 1999-02-02 | 2001-10-16 | Ortho-Clinical Diagnostics, Inc. | Oligonucleotide reverse transcription primers for efficient detection of HIV-1 and HIV-2 and methods of use thereof |
| AU3219400A (en) * | 1999-02-03 | 2000-08-25 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Methods and reagents for molecular detection of hiv-1 groups m, n and |
| DE19908766C2 (de) * | 1999-02-19 | 2001-02-15 | Ulrich Schubert | Verwendung synthetischer Vpr-Peptide des Humanen Immundefizienzvirus Typ 1 (HIV-1) zur Entwicklung von therapeutischen und diagnostischen Reagenzien |
| AU3438999A (en) * | 1999-05-07 | 2000-11-21 | Nationales Zentrum Fur Retroviren | Detection system for human immunodeficiency virus based on nucleic acid amplification |
| FR2798385B1 (fr) * | 1999-06-21 | 2003-09-05 | Bio Merieux | Procede de recherche d'une resistance aux anti-proteases chez des souches du virus vih-2 |
| ATE421999T1 (de) | 1999-07-09 | 2009-02-15 | Gen Probe Inc | Nachweis von hiv-1 durch amplifizierung von nukleinsäuren |
| US20030228600A1 (en) * | 2000-07-14 | 2003-12-11 | Eppendorf 5 Prime, Inc. | DNA isolation method and kit |
| US6582920B2 (en) | 2000-09-01 | 2003-06-24 | Gen-Probe Incorporated | Amplification of HIV-1 RT sequences for detection of sequences associated with drug-resistance mutations |
| EP2020450B9 (en) | 2000-09-01 | 2011-09-14 | Gen-Probe Incorporated | Amplification of HIV-1 sequences for detection of sequences associated with drug-resistance mutations |
| DE60132924T2 (de) | 2000-10-23 | 2009-03-05 | Gen-Probe Inc., San Diego | Zusammensetzungen und methoden zur detektion von humanem immundefizienz virus 2 (hiv-2) |
| US6770752B2 (en) | 2001-01-09 | 2004-08-03 | Becton, Dickinson And Company | Sequences for detection of HIV-1 |
| AU2002252192A1 (en) * | 2001-03-05 | 2002-09-19 | Visible Genetics Inc. | Methods and primers for evaluating hiv-1 mutations |
| JP4701532B2 (ja) * | 2001-04-26 | 2011-06-15 | 東ソー株式会社 | Ｈｉｖ−１ｒｎａの増幅および検出法 |
| WO2003051388A2 (en) * | 2001-12-18 | 2003-06-26 | Mondobiotech Laboratories Anstalt | Pharmaceutical composition of interferon gamma or pirfenidone with molecular diagnostics for the improved treatment of interstitial lung diseases |
| WO2003062377A2 (en) * | 2002-01-17 | 2003-07-31 | The Uab Research Foundation | COMPLETE GENOME SEQUENCE OF SIVcpzTAN1 |
| CN1301263C (zh) | 2002-12-18 | 2007-02-21 | 北京昭衍新药研究中心 | 一组抗hiv感染及防治艾滋病的核苷酸序列及其应用 |
| US20050222068A1 (en) | 2003-10-23 | 2005-10-06 | Mourich Dan V | Method and antisense composition for selective inhibition of HIV infection in hematopoietic cells |
| EP1694871B1 (en) * | 2003-12-19 | 2010-08-25 | Gen-Probe Incorporated | Compositions, methods and kits for detecting the nucleic acids of hiv-1 and hiv-2 |
| TW200613554A (en) | 2004-06-17 | 2006-05-01 | Wyeth Corp | Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV |
| EP1765867B1 (en) | 2004-07-01 | 2015-12-09 | The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services | Monoclonal antibodies to hiv-1 vpr and methods of using same |
| EP1794327B1 (en) | 2004-09-14 | 2016-11-30 | Argos Therapeutics, Inc. | Strain independent amplification of pathogens and vaccines thereto |
| US20090050492A1 (en) * | 2005-08-02 | 2009-02-26 | Board Of Trustees Of Michigan State University | Nanoporous silicon-based electrochemical nucleic acid biosensor |
| WO2008115427A2 (en) * | 2007-03-16 | 2008-09-25 | 454 Life Sciences Corporation | System and method for detection of hiv drug resistant variants |
| WO2009017743A2 (en) | 2007-07-30 | 2009-02-05 | Argos Therapeutics, Inc. | Improved primers and probes for the amplification and detection of hiv gag, rev and nef polynucleotides |
| US8405379B1 (en) | 2008-09-18 | 2013-03-26 | Luc Montagnier | System and method for the analysis of DNA sequences in biological fluids |
| US10545149B2 (en) * | 2008-10-06 | 2020-01-28 | Morehouse School Of Medicine | Detection of HIV-related proteins in urine |
| CA2746508A1 (en) | 2008-12-17 | 2010-07-15 | Avi Biopharma, Inc. | Antisense compositions and methods for modulating contact hypersensitivity or contact dermatitis |
| AU2011230619C1 (en) | 2010-03-25 | 2016-06-23 | Oregon Health & Science University | CMV glycoproteins and recombinant vectors |
| LT2691530T (lt) | 2011-06-10 | 2018-08-10 | Oregon Health & Science University | Cmv glikoproteinai ir rekombinantiniai vektoriai |
| CN102964898B (zh) | 2011-08-05 | 2016-05-25 | 罗门哈斯公司 | 具有改进的亲水污渍排斥性的水性涂料组合物 |
| US20130189754A1 (en) | 2011-09-12 | 2013-07-25 | International Aids Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies |
| US9402894B2 (en) | 2011-10-27 | 2016-08-02 | International Aids Vaccine Initiative | Viral particles derived from an enveloped virus |
| EP2679596B1 (en) | 2012-06-27 | 2017-04-12 | International Aids Vaccine Initiative | HIV-1 env glycoprotein variant |
| US20150065381A1 (en) | 2013-09-05 | 2015-03-05 | International Aids Vaccine Initiative | Methods of identifying novel hiv-1 immunogens |
| US10058604B2 (en) | 2013-10-07 | 2018-08-28 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| US10174292B2 (en) | 2015-03-20 | 2019-01-08 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| EP3072901A1 (en) | 2015-03-23 | 2016-09-28 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0387914B1 (en) * | 1984-10-18 | 1993-08-04 | Institut Pasteur | Envelope antigens of the human immuno-deficiency virus, and their applications |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| AU606043B2 (en) * | 1985-03-28 | 1991-01-31 | F. Hoffmann-La Roche Ag | Detection of viruses by amplification and hybridization |
| US5176995A (en) | 1985-03-28 | 1993-01-05 | Hoffmann-La Roche Inc. | Detection of viruses by amplification and hybridization |
| US5008182A (en) * | 1986-01-10 | 1991-04-16 | Cetus Corporation | Detection of AIDS associated virus by polymerase chain reaction |
| US5386022A (en) * | 1985-03-28 | 1995-01-31 | Hoffman-La Roche Inc. | Primes and probes for the amplification and detection of aids associated nucleic acids |
| ES8706823A1 (es) | 1985-03-28 | 1987-06-16 | Cetus Corp | Un procedimiento para detectar la presencia o ausencia de al menos una secuencia especifica de acidos nucleicos en una muestra |
| US5008185A (en) | 1985-11-04 | 1991-04-16 | Cell Analysis Systems, Inc. | Methods and apparatus for the quantitation of nuclear proteins |
| US4839288A (en) * | 1986-01-22 | 1989-06-13 | Institut Pasteur | Retrovirus capable of causing AIDS, antigens obtained from this retrovirus and corresponding antibodies and their application for diagnostic purposes |
| EP0239425B1 (fr) | 1986-01-22 | 1989-11-02 | Institut Pasteur | Rétrovirus du type HIV-2 susceptible de provoquer le SIDA, et ses constituants antigéniques et nucléiques |
| US4806463A (en) * | 1986-05-23 | 1989-02-21 | Worcester Foundation For Experimental Biology | Inhibition of HTLV-III by exogenous oligonucleotides |
| US5030714A (en) * | 1986-06-23 | 1991-07-09 | Institut Pasteur | Variant of LAV viruses |
| US5824482A (en) * | 1986-06-23 | 1998-10-20 | Institut Pasteur | Purification, cloning, and characterization of a novel human immunodeficiency virus LAVMAL |
| DE3785658T2 (de) * | 1986-08-11 | 1993-08-12 | Siska Diagnostics Inc | Methoden und zusammensetzungen fuer tests mit nukleinsaeuresonden. |
| EP0269520A3 (fr) * | 1986-11-21 | 1988-08-24 | Institut Pasteur | Rétrovirus du type HIV-2 susceptible de provoquer le sida, et ses constituants antigéniques et nucléiques |
| US5268268A (en) | 1986-11-26 | 1993-12-07 | Hoffmann-La Roche Inc. | Detection of HTLVI and HTLVII viruses by hybridization |
| US5079351A (en) * | 1986-11-26 | 1992-01-07 | Cetus Corporation | Oligonucleotides and kits for detection of htlvi and htlvii viruses by hybridization |
| EP0272098A3 (en) * | 1986-12-15 | 1990-06-06 | City Of Hope National Medical Center | Method for amplification and detection of rna sequences |
| EP0283327B1 (fr) * | 1987-01-16 | 1997-06-25 | Institut Pasteur | Peptides ayant des propriétés immunologiques de HIV-2 |
| WO1989001050A1 (en) | 1987-07-31 | 1989-02-09 | The Board Of Trustees Of The Leland Stanford Junior University | Selective amplification of target polynucleotide sequences |
| US4963532A (en) | 1987-11-25 | 1990-10-16 | Hem Research, Inc. | dsRNA-based prevention of viral escape |
| US5389512A (en) | 1988-10-07 | 1995-02-14 | Hoffman-La Roche Inc. | Method for determining the relative amount of a viral nucleic acid segment in a sample by the polymerase chain reaction |
| FR2647856B1 (fr) * | 1989-05-31 | 1994-03-04 | Framatome | Dispositif auxiliaire de relachement commande a distance pour un mecanisme a action positive |
| ES2262166T3 (es) * | 1989-06-02 | 2006-11-16 | Institut Pasteur | Sintesis de proteinas o polipeptidos codificados por un secuencia nucleotidica vih-1, vih-2 o siv. |
-
1990
- 1990-06-05 ES ES97110543T patent/ES2262166T3/es not_active Expired - Lifetime
- 1990-06-05 DE DE69034220T patent/DE69034220T2/de not_active Expired - Lifetime
- 1990-06-05 WO PCT/FR1990/000393 patent/WO1990015066A2/fr active Application Filing
- 1990-06-05 AT AT06013029T patent/ATE423856T1/de not_active IP Right Cessation
- 1990-06-05 DK DK90401520T patent/DK0403333T3/da active
- 1990-06-05 AT AT05014676T patent/ATE404699T1/de not_active IP Right Cessation
- 1990-06-05 DE DE69034260T patent/DE69034260D1/de not_active Expired - Lifetime
- 1990-06-05 ES ES07025195T patent/ES2315215T1/es active Pending
- 1990-06-05 EP EP07025195A patent/EP2011888B1/fr not_active Expired - Lifetime
- 1990-06-05 DK DK97110543T patent/DK0806484T3/da active
- 1990-06-05 EP EP06013029A patent/EP1715064B1/fr not_active Expired - Lifetime
- 1990-06-05 ES ES06013029T patent/ES2321326T3/es not_active Expired - Lifetime
- 1990-06-05 EP EP90401520A patent/EP0403333B1/fr not_active Expired - Lifetime
- 1990-06-05 DE DE05014676T patent/DE05014676T1/de active Pending
- 1990-06-05 DE DE07025195T patent/DE07025195T1/de active Pending
- 1990-06-05 CA CA002062829A patent/CA2062829C/fr not_active Expired - Lifetime
- 1990-06-05 DK DK05014676T patent/DK1642987T3/da active
- 1990-06-05 DE DE69034265T patent/DE69034265D1/de not_active Expired - Lifetime
- 1990-06-05 CA CA002585164A patent/CA2585164C/fr not_active Expired - Lifetime
- 1990-06-05 EP EP05014676A patent/EP1642987B1/fr not_active Expired - Lifetime
- 1990-06-05 AT AT97110543T patent/ATE323183T1/de not_active IP Right Cessation
- 1990-06-05 CA CA002685262A patent/CA2685262A1/fr not_active Abandoned
- 1990-06-05 AT AT07025195T patent/ATE466111T1/de not_active IP Right Cessation
- 1990-06-05 ES ES90401520T patent/ES2139567T3/es not_active Expired - Lifetime
- 1990-06-05 SG SG1996004845A patent/SG47868A1/en unknown
- 1990-06-05 JP JP50891190A patent/JP3428012B2/ja not_active Expired - Lifetime
- 1990-06-05 DE DE69033311T patent/DE69033311T2/de not_active Expired - Lifetime
- 1990-06-05 DK DK07025195.4T patent/DK2011888T3/da active
- 1990-06-05 DK DK06013029T patent/DK1715064T3/da active
- 1990-06-05 DE DE69034267T patent/DE69034267D1/de not_active Expired - Lifetime
- 1990-06-05 ES ES05014676T patent/ES2275451T3/es not_active Expired - Lifetime
- 1990-06-05 EP EP97110543A patent/EP0806484B1/fr not_active Expired - Lifetime
- 1990-06-05 AT AT90401520T patent/ATE185379T1/de not_active IP Right Cessation
-
1993
- 1993-12-02 US US08/160,465 patent/US5688637A/en not_active Expired - Fee Related
-
1995
- 1995-06-07 US US08/472,928 patent/US7078516B1/en not_active Expired - Lifetime
-
1997
- 1997-07-16 US US08/895,231 patent/US5786177A/en not_active Expired - Lifetime
-
1998
- 1998-06-05 US US09/092,077 patent/US6194142B1/en not_active Expired - Lifetime
-
1999
- 1999-09-24 JP JP11270165A patent/JP2000093187A/ja active Pending
- 1999-12-28 GR GR990403346T patent/GR3032261T3/el unknown
-
2004
- 2004-06-08 US US10/862,363 patent/US7759477B2/en not_active Expired - Lifetime
-
2005
- 2005-08-15 US US11/203,127 patent/US7777020B2/en not_active Expired - Lifetime
-
2006
- 2006-09-21 HK HK07103317.3A patent/HK1097574A1/xx not_active IP Right Cessation
- 2006-09-21 HK HK09100744.0A patent/HK1125136A1/xx unknown
- 2006-09-21 HK HK06110565.8A patent/HK1092839A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0806484T3 (da) | Syntese af proteiner eller polypeptider kodet af en nucleotidsekvens af HIV-1, HIV-2 eller SIV. | |
| Kwoh et al. | Transcription-based amplification system and detection of amplified human immunodeficiency virus type 1 with a bead-based sandwich hybridization format. | |
| KR0148265B1 (ko) | 자가-지속 서열 복제 시스템 | |
| US5389512A (en) | Method for determining the relative amount of a viral nucleic acid segment in a sample by the polymerase chain reaction | |
| JP3802110B2 (ja) | 核酸の同時増幅方法並びにそのための組成物、試験キット及び試験装置 | |
| KR100901084B1 (ko) | Ｈｉｖ-1 및 ｈｉｖ-2를 효율적으로 검출하기 위한 올리고뉴클레오타이드 역전사 프라이머, 이의 사용 방법 및 이를 포함하는 키트 | |
| KR870007427A (ko) | 증폭 및 하이브리드화로 바이러스를 검출하는 방법 | |
| DE50113454D1 (de) | Verfahren zur bestimmung des methylierungsgrades von bestimmten cytosinen in genomischer dna im sequenzkontext 5'-cpg-3' | |
| US5384242A (en) | Diagnostic kit, primer composition and their use for replication or detection of nucleic acids | |
| RU98100921A (ru) | Праймеры для обнаружения вич-1 | |
| JP2004500014A (ja) | Ｈｉｖを検出するための新規のプライマーおよびプローブ | |
| RU2010154139A (ru) | Способ обнаружения респираторных вирусных агентов в образце | |
| JP6164590B2 (ja) | ウシ白血病ウイルス検出用プライマーセット、及びその利用 | |
| CN114369649A (zh) | 一种特异的选择扩增及多重pcr方法和应用 | |
| JP2012503472A (ja) | 診断用ハイブリダイゼーションアッセイにおける核酸標的の配列変異に対する依存性を低下させるための方法 | |
| JP2020146066A5 (da) | ||
| CN100359021C (zh) | 一种通用引物联合标记法 | |
| RU2021134298A (ru) | Способ получения молекулярных маркеров для идентификации личности на основе аутосомных STR-маркеров методом мультиплексной амплификации | |
| DK200401109A (da) | Kit til multiplicering og påvisning af nukleinsyresekvenser |