DK0804479T3 - Fremgangsmåde til behandling af diabetes mellitus ved anvendelse af KGF - Google Patents
Fremgangsmåde til behandling af diabetes mellitus ved anvendelse af KGFInfo
- Publication number
- DK0804479T3 DK0804479T3 DK95934808T DK95934808T DK0804479T3 DK 0804479 T3 DK0804479 T3 DK 0804479T3 DK 95934808 T DK95934808 T DK 95934808T DK 95934808 T DK95934808 T DK 95934808T DK 0804479 T3 DK0804479 T3 DK 0804479T3
- Authority
- DK
- Denmark
- Prior art keywords
- kgf
- diabetes mellitus
- treating diabetes
- mammals
- pharmaceutical compositions
- Prior art date
Links
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 2
- 102000003972 Fibroblast growth factor 7 Human genes 0.000 abstract 1
- 108090000385 Fibroblast growth factor 7 Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32334094A | 1994-10-13 | 1994-10-13 | |
| US32347594A | 1994-10-13 | 1994-10-13 | |
| US48782595A | 1995-06-07 | 1995-06-07 | |
| PCT/IB1995/000992 WO1996011950A1 (en) | 1994-10-13 | 1995-10-12 | Method of treating diabetes mellitus using kgf |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0804479T3 true DK0804479T3 (da) | 2007-01-29 |
Family
ID=27406268
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95934793T DK0785948T3 (da) | 1994-10-13 | 1995-10-12 | Analoger af keratinocyt vækstfaktor |
| DK95934808T DK0804479T3 (da) | 1994-10-13 | 1995-10-12 | Fremgangsmåde til behandling af diabetes mellitus ved anvendelse af KGF |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95934793T DK0785948T3 (da) | 1994-10-13 | 1995-10-12 | Analoger af keratinocyt vækstfaktor |
Country Status (23)
| Country | Link |
|---|---|
| EP (2) | EP0804479B1 (da) |
| JP (2) | JP4216329B2 (da) |
| KR (1) | KR100278597B1 (da) |
| CN (1) | CN1168678A (da) |
| AT (2) | ATE237633T1 (da) |
| AU (1) | AU3707795A (da) |
| BG (2) | BG101392A (da) |
| BR (2) | BR9509269A (da) |
| CA (2) | CA2202075C (da) |
| CZ (3) | CZ297329B6 (da) |
| DE (2) | DE69530403T2 (da) |
| DK (2) | DK0785948T3 (da) |
| EE (2) | EE03975B1 (da) |
| ES (2) | ES2273338T3 (da) |
| FI (2) | FI971420A0 (da) |
| HU (2) | HU226168B1 (da) |
| NO (2) | NO318761B1 (da) |
| NZ (2) | NZ505502A (da) |
| PL (2) | PL320484A1 (da) |
| PT (2) | PT785948E (da) |
| SI (2) | SI0804479T1 (da) |
| SK (2) | SK43197A3 (da) |
| WO (2) | WO1996011949A2 (da) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0555205B1 (en) | 1989-01-31 | 2000-11-29 | RUBIN, Jeffrey S | Dna encoding a growth factor specific for epithelial cells |
| BR9407035A (pt) | 1993-06-29 | 1996-03-12 | Chiron Corp | Fragmento de fator de crescimento de queratinócitos conjugado composição terapêutica molécula de DNA vetor de expressão célula hospedeira processo para produzir fragmento de fator de crescimento de queratinócitos processo para cicatrização de ferimento e processo de tratamento de doença hiperproliferativa da epiderme |
| US7084119B2 (en) | 1993-06-29 | 2006-08-01 | Chiron Corporation | Truncated keratinocyte growth factor (KGF) having increased biological activity |
| IL147575A (en) * | 1994-10-13 | 2004-05-12 | Amgen Inc | Method for purifying keratinocyte growth factors |
| US7232667B2 (en) | 1995-02-14 | 2007-06-19 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 polynucleotides |
| US6693077B1 (en) | 1995-02-14 | 2004-02-17 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 |
| US6077692A (en) | 1995-02-14 | 2000-06-20 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 |
| WO1996034017A1 (en) * | 1995-04-27 | 1996-10-31 | Coöperatie Suiker Unie U.A. | Inulin derivatives |
| WO1998016642A1 (en) * | 1996-10-15 | 1998-04-23 | Amgen Inc. | Keratinocyte growth factor-2 products |
| SI0935652T1 (en) * | 1996-10-15 | 2004-06-30 | Amgen Inc. | Keratinocyte growth factor-2 products |
| US6743422B1 (en) | 1996-10-15 | 2004-06-01 | Amgen, Inc. | Keratinocyte growth factor-2 products |
| US20080076706A1 (en) | 1997-07-14 | 2008-03-27 | Bolder Biotechnology, Inc. | Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof |
| WO2000042175A1 (en) * | 1999-01-14 | 2000-07-20 | Bolder Biotechnology Inc. | Methods for making proteins containing free cysteine residues |
| DE69838552T2 (de) | 1997-07-14 | 2008-05-21 | Bolder Biotechnology, Inc., Louisville | Derivate des wachstumshormons und verwandte proteine |
| US7153943B2 (en) | 1997-07-14 | 2006-12-26 | Bolder Biotechnology, Inc. | Derivatives of growth hormone and related proteins, and methods of use thereof |
| US7495087B2 (en) | 1997-07-14 | 2009-02-24 | Bolder Biotechnology, Inc. | Cysteine muteins in the C-D loop of human interleukin-11 |
| JP2001526239A (ja) | 1997-12-22 | 2001-12-18 | ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド | 角質細胞増殖因子−２製剤 |
| US6869927B1 (en) | 1997-12-22 | 2005-03-22 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 formulations |
| US6242666B1 (en) * | 1998-12-16 | 2001-06-05 | The Scripps Research Institute | Animal model for identifying a common stem/progenitor to liver cells and pancreatic cells |
| US8288126B2 (en) | 1999-01-14 | 2012-10-16 | Bolder Biotechnology, Inc. | Methods for making proteins containing free cysteine residues |
| US6248725B1 (en) | 1999-02-23 | 2001-06-19 | Amgen, Inc. | Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction |
| PL362397A1 (en) * | 2001-02-06 | 2004-11-02 | Merck Patent Gmbh | Modified keratinocyte growth factor (kgf) with reduced immunogenicity |
| JP2005500390A (ja) | 2001-08-21 | 2005-01-06 | カイロン コーポレイション | Ｋｇｆポリペプチド組成物 |
| AU2007214362B2 (en) * | 2001-08-21 | 2009-11-26 | Novartis Vaccines And Diagnostics, Inc. | KGF polypeptide compositions |
| RS53548B1 (sr) | 2004-12-15 | 2015-02-27 | Swedish Orphan Biovitrum Ab (Publ) | Terapeutske formulacije faktora rasta keratinocita |
| CN102242124B (zh) * | 2010-05-10 | 2013-05-22 | 齐鲁制药有限公司 | 改造的角化细胞生长因子基因及其在酵母中的表达 |
| KR102440312B1 (ko) * | 2020-08-28 | 2022-09-05 | 한국해양과학기술원 | 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4959314A (en) * | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
| JPH01137994A (ja) * | 1987-08-10 | 1989-05-30 | Shionogi & Co Ltd | ｒｅｇ蛋白質 |
| WO1990000877A1 (en) * | 1988-07-27 | 1990-02-08 | Marjan International Pty Ltd | Carpet stretcher |
| EP0555205B1 (en) * | 1989-01-31 | 2000-11-29 | RUBIN, Jeffrey S | Dna encoding a growth factor specific for epithelial cells |
| JP3303211B2 (ja) * | 1991-04-26 | 2002-07-15 | 武田薬品工業株式会社 | ｂＦＧＦムテインおよびその製造法 |
| RU2146148C1 (ru) * | 1993-03-26 | 2000-03-10 | Амген Инк. | Терапевтическое применение фактора роста кератиноцитов (фрк) |
| BR9407035A (pt) * | 1993-06-29 | 1996-03-12 | Chiron Corp | Fragmento de fator de crescimento de queratinócitos conjugado composição terapêutica molécula de DNA vetor de expressão célula hospedeira processo para produzir fragmento de fator de crescimento de queratinócitos processo para cicatrização de ferimento e processo de tratamento de doença hiperproliferativa da epiderme |
| US5348563A (en) * | 1993-06-29 | 1994-09-20 | Honeywell Inc. | Air purifying apparatus |
| GB9315501D0 (en) * | 1993-07-27 | 1993-09-08 | Ici Plc | Surfactant compositions |
| JPH09503751A (ja) * | 1993-08-02 | 1997-04-15 | プリズム ファーマシュティカルズ，インコーポレイティド | 細胞毒性抱合体の単一起源性製剤 |
-
1995
- 1995-10-12 PT PT95934793T patent/PT785948E/pt unknown
- 1995-10-12 PL PL95320484A patent/PL320484A1/xx unknown
- 1995-10-12 EP EP95934808A patent/EP0804479B1/en not_active Expired - Lifetime
- 1995-10-12 ES ES95934808T patent/ES2273338T3/es not_active Expired - Lifetime
- 1995-10-12 BR BR9509269A patent/BR9509269A/pt not_active Application Discontinuation
- 1995-10-12 WO PCT/IB1995/000971 patent/WO1996011949A2/en not_active Ceased
- 1995-10-12 AU AU37077/95A patent/AU3707795A/en not_active Abandoned
- 1995-10-12 HU HU9901255A patent/HU226168B1/hu not_active IP Right Cessation
- 1995-10-12 WO PCT/IB1995/000992 patent/WO1996011950A1/en not_active Ceased
- 1995-10-12 CA CA002202075A patent/CA2202075C/en not_active Expired - Fee Related
- 1995-10-12 KR KR1019970702343A patent/KR100278597B1/ko not_active Expired - Fee Related
- 1995-10-12 CA CA002201940A patent/CA2201940C/en not_active Expired - Fee Related
- 1995-10-12 BR BR9509329A patent/BR9509329A/pt not_active Application Discontinuation
- 1995-10-12 DK DK95934793T patent/DK0785948T3/da active
- 1995-10-12 NZ NZ505502A patent/NZ505502A/en not_active IP Right Cessation
- 1995-10-12 JP JP51307796A patent/JP4216329B2/ja not_active Expired - Fee Related
- 1995-10-12 DE DE69530403T patent/DE69530403T2/de not_active Expired - Lifetime
- 1995-10-12 EP EP95934793A patent/EP0785948B1/en not_active Expired - Lifetime
- 1995-10-12 CN CN95196410A patent/CN1168678A/zh active Pending
- 1995-10-12 FI FI971420A patent/FI971420A0/fi unknown
- 1995-10-12 PL PL95319784A patent/PL182888B1/pl not_active IP Right Cessation
- 1995-10-12 SK SK431-97A patent/SK43197A3/sk unknown
- 1995-10-12 HU HU9901071A patent/HUT78050A/hu unknown
- 1995-10-12 EE EE9700081A patent/EE03975B1/xx not_active IP Right Cessation
- 1995-10-12 AT AT95934793T patent/ATE237633T1/de active
- 1995-10-12 CZ CZ20023953A patent/CZ297329B6/cs not_active IP Right Cessation
- 1995-10-12 CZ CZ0105097A patent/CZ297328B6/cs not_active IP Right Cessation
- 1995-10-12 SI SI9530728T patent/SI0804479T1/sl unknown
- 1995-10-12 DE DE69535264T patent/DE69535264T2/de not_active Expired - Lifetime
- 1995-10-12 SI SI9530654T patent/SI0785948T1/xx unknown
- 1995-10-12 ES ES95934793T patent/ES2196082T3/es not_active Expired - Lifetime
- 1995-10-12 CZ CZ97981A patent/CZ98197A3/cs unknown
- 1995-10-12 EE EE9700225A patent/EE9700225A/xx unknown
- 1995-10-12 SK SK455-97A patent/SK284534B6/sk not_active IP Right Cessation
- 1995-10-12 JP JP51307696A patent/JP4426646B2/ja not_active Expired - Fee Related
- 1995-10-12 PT PT95934808T patent/PT804479E/pt unknown
- 1995-10-12 DK DK95934808T patent/DK0804479T3/da active
- 1995-10-12 AT AT95934808T patent/ATE342278T1/de active
-
1997
- 1997-04-04 NO NO19971568A patent/NO318761B1/no not_active IP Right Cessation
- 1997-04-04 NO NO971566A patent/NO971566L/no unknown
- 1997-04-07 BG BG101392A patent/BG101392A/xx unknown
- 1997-04-11 BG BG101408A patent/BG63167B1/bg unknown
- 1997-04-11 FI FI971536A patent/FI120040B/fi not_active IP Right Cessation
-
1999
- 1999-04-09 NZ NZ335109A patent/NZ335109A/xx not_active IP Right Cessation
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