DK0804439T3 - Beta, beta'-dihydroxy-mesosubstituerede chloriner, -isobacteriochloriner, -bacteriochloriner og fremgangsmåder til fremstilling af samme ud fra beta, beta'-usubstituerede tetrapyrroliske, makrocykliske forbindelser - Google Patents

Beta, beta'-dihydroxy-mesosubstituerede chloriner, -isobacteriochloriner, -bacteriochloriner og fremgangsmåder til fremstilling af samme ud fra beta, beta'-usubstituerede tetrapyrroliske, makrocykliske forbindelser

Info

Publication number
DK0804439T3
DK0804439T3 DK95944791T DK95944791T DK0804439T3 DK 0804439 T3 DK0804439 T3 DK 0804439T3 DK 95944791 T DK95944791 T DK 95944791T DK 95944791 T DK95944791 T DK 95944791T DK 0804439 T3 DK0804439 T3 DK 0804439T3
Authority
DK
Denmark
Prior art keywords
beta
dihydroxy
unsubstituted
mesosubstituted
isobacteriochlorines
Prior art date
Application number
DK95944791T
Other languages
Danish (da)
English (en)
Inventor
David Dolphin
Christian Department Bruckner
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Application granted granted Critical
Publication of DK0804439T3 publication Critical patent/DK0804439T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Radiology & Medical Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK95944791T 1994-10-26 1995-10-25 Beta, beta'-dihydroxy-mesosubstituerede chloriner, -isobacteriochloriner, -bacteriochloriner og fremgangsmåder til fremstilling af samme ud fra beta, beta'-usubstituerede tetrapyrroliske, makrocykliske forbindelser DK0804439T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/329,577 US5648485A (en) 1994-10-26 1994-10-26 β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
PCT/CA1995/000602 WO1996013504A1 (en) 1994-10-26 1995-10-25 β,β'-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, BACTERIOCHLORINS, AND METHODS FOR MAKING THE SAME FROM β,β'-UNSUBSTITUTED TETRAPYRROLIC MACROCYCLES

Publications (1)

Publication Number Publication Date
DK0804439T3 true DK0804439T3 (da) 2004-02-02

Family

ID=23286058

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95944791T DK0804439T3 (da) 1994-10-26 1995-10-25 Beta, beta'-dihydroxy-mesosubstituerede chloriner, -isobacteriochloriner, -bacteriochloriner og fremgangsmåder til fremstilling af samme ud fra beta, beta'-usubstituerede tetrapyrroliske, makrocykliske forbindelser

Country Status (20)

Country Link
US (2) US5648485A (hu)
EP (1) EP0804439B1 (hu)
JP (2) JP3228296B2 (hu)
KR (1) KR970707129A (hu)
CN (1) CN1043143C (hu)
AT (1) ATE250064T1 (hu)
AU (1) AU704971B2 (hu)
CA (1) CA2199399C (hu)
CZ (1) CZ294496B6 (hu)
DE (1) DE69531795T2 (hu)
DK (1) DK0804439T3 (hu)
ES (1) ES2208701T3 (hu)
FI (1) FI971734A0 (hu)
HU (1) HU221102B1 (hu)
NO (1) NO308411B1 (hu)
NZ (1) NZ294203A (hu)
PL (1) PL182239B1 (hu)
PT (1) PT804439E (hu)
TW (1) TW301648B (hu)
WO (1) WO1996013504A1 (hu)

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US5648485A (en) * 1994-10-26 1997-07-15 University Of British Columbia β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
GB9610967D0 (en) 1996-05-24 1996-07-31 Cambridge Antibody Tech Specific binding members,materials and methods
JP2001514617A (ja) * 1997-01-21 2001-09-11 ジ・アメリカン・ナショナル・レッド・クロス 両親媒性フェノチアジン−５−イウム染料と光による全血および血液成分の細胞内および細胞外汚染除去
EP1091742A4 (en) 1997-02-14 2007-05-30 Miravant Pharm Inc PHOTOSENSITIVE INDIUM, FOR TPD
FR2760841B1 (fr) * 1997-03-12 1999-04-16 Commissariat Energie Atomique Determination par resonance magnetique nucleaire de la configuration absolue d'amino-acides ou de leur derives et complexes metalliques de porphyrines chirales utilisables pour cette determination
DE19814405C2 (de) 1998-03-31 2000-03-02 Schastak Astrid Porphyrine und ihre Verwendung als Photosensitizer
US20030176663A1 (en) * 1998-05-11 2003-09-18 Eidgenossische Technische Hochscule Specific binding molecules for scintigraphy
JP2002527606A (ja) 1998-10-20 2002-08-27 ザ、プロクター、エンド、ギャンブル、カンパニー 改良アルキルベンゼンスルホネートを含有した洗濯洗剤
EP1123369B1 (en) 1998-10-20 2006-03-01 The Procter & Gamble Company Laundry detergents comprising modified alkylbenzene sulfonates
AU4278400A (en) * 1999-04-14 2000-11-14 University Of British Columbia, The Improved beta,beta,-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US7022843B1 (en) 1999-04-14 2006-04-04 The University Of British Columbia β,β′-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US20020022032A1 (en) * 1999-04-23 2002-02-21 Curry Patrick Mark Immuno-adjuvant PDT treatment of metastatic tumors
US6376483B1 (en) 1999-05-27 2002-04-23 Miravant Pharmaceuticals, Inc. Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production
US7897140B2 (en) * 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
CA2400622A1 (en) 2000-02-24 2001-08-30 Eidgenossische Technische Hochschule Zurich Antibody specific for the ed-b domain of fibronectin, conjugates comprising said antibody, and their use for the detection and treatment of angiogenesis
AU2001258095A1 (en) * 2000-05-08 2001-11-20 The University Of British Columbia Drug delivery systems for photodynamic therapy
CA2408332C (en) 2000-05-08 2011-02-15 The University Of British Columbia Supports for photosensitizer formulations
US6559374B2 (en) * 2000-07-21 2003-05-06 North Carolina State University Trans beta substituted chlorins and methods of making and using the same
EP1381629B1 (de) * 2000-09-07 2008-09-10 Bayer Schering Pharma Aktiengesellschaft REZEPTOR DER EDb-FIBRONEKTIN-DOMÄNE (II)
JP4944348B2 (ja) * 2000-09-08 2012-05-30 三栄源エフ・エフ・アイ株式会社 テトラフェニルバクテリオクロリン誘導体およびそれを含む組成物
EP1443964B1 (en) * 2001-11-09 2008-02-20 QLT Inc. Photodynamic therapy for the treatment of hair loss
EP1517684B1 (en) 2002-06-27 2009-07-22 Health Research, Inc. Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy
WO2004005289A2 (en) * 2002-07-02 2004-01-15 Health Research, Inc. Efficient synthesis of pyropheophorbide a and its derivatives
CA2513133A1 (en) * 2003-01-16 2004-07-29 Techno Mart Co., Ltd. Porphyrin derivatives
US7057100B2 (en) * 2003-06-26 2006-06-06 The J.C. Robinson Seed Co. Inbred corn line W23129
GB0323358D0 (en) * 2003-10-06 2003-11-05 Green Grass Design Ltd Novel compounds and processes
JP4635493B2 (ja) * 2003-10-09 2011-02-23 日本製紙株式会社 ダル調塗工紙
GB2408265A (en) * 2003-11-21 2005-05-25 Univ Sheffield Water-soluble hyperbranched polymer porphyrins
US6995260B2 (en) * 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
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US8187824B2 (en) * 2005-11-30 2012-05-29 North Carolina State University Porphyrinic compounds for use in flow cytometry
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US8253725B2 (en) * 2007-12-28 2012-08-28 St. Jude Medical, Atrial Fibrillation Division, Inc. Method and system for generating surface models of geometric structures
US20120034155A1 (en) * 2010-08-03 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Artificial cells
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US9226917B2 (en) 2008-12-16 2016-01-05 Valeant Pharmaceuticals International, Inc. Photodynamic therapy for conditions of the eye
US9211283B2 (en) 2009-12-11 2015-12-15 Biolitec Pharma Marketing Ltd Nanoparticle carrier systems based on human serum albumin for photodynamic therapy
CN106995493B (zh) 2010-02-04 2021-09-24 卫材公司 氯毒素多肽和结合物及其应用
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RU2615770C1 (ru) * 2015-12-21 2017-04-11 Общество с ограниченной ответственностью "Пермская химическая компания" Борированные производные фторированных бактериохлоринов и их металлокомплексов, обладающие противоопухолевой активностью
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Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648485A (en) * 1994-10-26 1997-07-15 University Of British Columbia β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US6376483B1 (en) * 1999-05-27 2002-04-23 Miravant Pharmaceuticals, Inc. Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production

Also Published As

Publication number Publication date
AU704971B2 (en) 1999-05-13
MX9703013A (es) 1997-07-31
US5831088A (en) 1998-11-03
DE69531795D1 (de) 2003-10-23
FI971734A (fi) 1997-04-23
ES2208701T3 (es) 2004-06-16
CA2199399A1 (en) 1996-05-09
TW301648B (hu) 1997-04-01
JPH10507766A (ja) 1998-07-28
PL182239B1 (pl) 2001-11-30
AU3695195A (en) 1996-05-23
FI971734A0 (fi) 1997-04-23
HU221102B1 (en) 2002-08-28
NO308411B1 (no) 2000-09-11
ATE250064T1 (de) 2003-10-15
CN1161697A (zh) 1997-10-08
HUT77008A (hu) 1998-03-02
PT804439E (pt) 2004-02-27
JP2001294589A (ja) 2001-10-23
US5648485A (en) 1997-07-15
DE69531795T2 (de) 2004-08-05
WO1996013504A1 (en) 1996-05-09
EP0804439A1 (en) 1997-11-05
CN1043143C (zh) 1999-04-28
JP3228296B2 (ja) 2001-11-12
KR970707129A (ko) 1997-12-01
NO971952D0 (no) 1997-04-25
CZ115597A3 (en) 1997-09-17
NZ294203A (en) 1998-12-23
PL319907A1 (en) 1997-09-01
EP0804439B1 (en) 2003-09-17
CZ294496B6 (cs) 2005-01-12
NO971952L (no) 1997-04-25
CA2199399C (en) 2004-02-24

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