HUT77008A - Mezo-szubsztituált klorin, bakterioklorin, izobakterioklorin béta,béta'-hidroxi-származékai és eljárás béta,béta' helyeken nem szubsztituált tetrapirrol makrociklusos vegyületekből történő előállításukra - Google Patents

Mezo-szubsztituált klorin, bakterioklorin, izobakterioklorin béta,béta'-hidroxi-származékai és eljárás béta,béta' helyeken nem szubsztituált tetrapirrol makrociklusos vegyületekből történő előállításukra

Info

Publication number
HUT77008A
HUT77008A HU9701702A HU9701702A HUT77008A HU T77008 A HUT77008 A HU T77008A HU 9701702 A HU9701702 A HU 9701702A HU 9701702 A HU9701702 A HU 9701702A HU T77008 A HUT77008 A HU T77008A
Authority
HU
Hungary
Prior art keywords
beta
unsubstituted
isobacteriochlorins
bacteriochlorins
making
Prior art date
Application number
HU9701702A
Other languages
English (en)
Other versions
HU221102B1 (en
Inventor
Christian Bruckner
David Dolphin
Original Assignee
University Of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of British Columbia filed Critical University Of British Columbia
Publication of HUT77008A publication Critical patent/HUT77008A/hu
Publication of HU221102B1 publication Critical patent/HU221102B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
HU9701702A 1994-10-26 1995-10-25 Beta,beta'-dihydroxy meso-substituted chlorins, bacteriochlorins, isobacteriochlorins, and process for preparing thereof HU221102B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/329,577 US5648485A (en) 1994-10-26 1994-10-26 β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
PCT/CA1995/000602 WO1996013504A1 (en) 1994-10-26 1995-10-25 β,β'-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, BACTERIOCHLORINS, AND METHODS FOR MAKING THE SAME FROM β,β'-UNSUBSTITUTED TETRAPYRROLIC MACROCYCLES

Publications (2)

Publication Number Publication Date
HUT77008A true HUT77008A (hu) 1998-03-02
HU221102B1 HU221102B1 (en) 2002-08-28

Family

ID=23286058

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9701702A HU221102B1 (en) 1994-10-26 1995-10-25 Beta,beta'-dihydroxy meso-substituted chlorins, bacteriochlorins, isobacteriochlorins, and process for preparing thereof

Country Status (20)

Country Link
US (2) US5648485A (hu)
EP (1) EP0804439B1 (hu)
JP (2) JP3228296B2 (hu)
KR (1) KR970707129A (hu)
CN (1) CN1043143C (hu)
AT (1) ATE250064T1 (hu)
AU (1) AU704971B2 (hu)
CA (1) CA2199399C (hu)
CZ (1) CZ294496B6 (hu)
DE (1) DE69531795T2 (hu)
DK (1) DK0804439T3 (hu)
ES (1) ES2208701T3 (hu)
FI (1) FI971734A (hu)
HU (1) HU221102B1 (hu)
NO (1) NO308411B1 (hu)
NZ (1) NZ294203A (hu)
PL (1) PL182239B1 (hu)
PT (1) PT804439E (hu)
TW (1) TW301648B (hu)
WO (1) WO1996013504A1 (hu)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648485A (en) * 1994-10-26 1997-07-15 University Of British Columbia β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
GB9610967D0 (en) 1996-05-24 1996-07-31 Cambridge Antibody Tech Specific binding members,materials and methods
WO1998031219A1 (en) * 1997-01-21 1998-07-23 The American National Red Cross Intracellular and extracellular decontamination of whole blood and blood components by amphiphilic phenothiazin-5-ium dyes plus light
WO2000000204A1 (en) 1997-02-14 2000-01-06 Miravant Pharmaceuticals, Inc. Indium photosensitizers for pdt
FR2760841B1 (fr) * 1997-03-12 1999-04-16 Commissariat Energie Atomique Determination par resonance magnetique nucleaire de la configuration absolue d'amino-acides ou de leur derives et complexes metalliques de porphyrines chirales utilisables pour cette determination
DE19814405C2 (de) 1998-03-31 2000-03-02 Schastak Astrid Porphyrine und ihre Verwendung als Photosensitizer
US20030176663A1 (en) * 1998-05-11 2003-09-18 Eidgenossische Technische Hochscule Specific binding molecules for scintigraphy
BR9914678A (pt) 1998-10-20 2001-10-09 Procter & Gamble Detergentes para a lavagem de roupas compreendendo sulfonatos de alquilbenzeno modificados
AU763324B2 (en) 1998-10-20 2003-07-17 Procter & Gamble Company, The Laundry detergents comprising modified alkylbenzene sulfonates
WO2000061584A1 (en) * 1999-04-14 2000-10-19 The University Of British Columbia IMPROVED β,β,-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, AND BACTERIOCHLORINS
US7022843B1 (en) 1999-04-14 2006-04-04 The University Of British Columbia β,β′-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US20020022032A1 (en) * 1999-04-23 2002-02-21 Curry Patrick Mark Immuno-adjuvant PDT treatment of metastatic tumors
US6376483B1 (en) 1999-05-27 2002-04-23 Miravant Pharmaceuticals, Inc. Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production
US7897140B2 (en) * 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
EP1259548A1 (en) 2000-02-24 2002-11-27 Eidgenössische Technische Hochschule Zürich Antibody specific for the ed-b domain of fibronectin, conjugates comprising said antibody, and their use for the detection and treatment of angiogenesis
WO2001085213A2 (en) 2000-05-08 2001-11-15 The University Of British Columbia Supports for photosensitizer formulations
AU2001258095A1 (en) * 2000-05-08 2001-11-20 The University Of British Columbia Drug delivery systems for photodynamic therapy
US6559374B2 (en) * 2000-07-21 2003-05-06 North Carolina State University Trans beta substituted chlorins and methods of making and using the same
HUP0300935A3 (en) * 2000-09-07 2005-09-28 Schering Ag Receptor in the edb fibronectin domain
AU2001284466A1 (en) 2000-09-08 2002-03-22 San-Ei Gen F.F.I., Inc. Tetraphenylbacteriochlorin derivatives and compositions containing the same
AU2002340659B2 (en) * 2001-11-09 2008-04-10 Qlt Inc. Photodynamic therapy for the treatment of hair loss
EP1517684B1 (en) 2002-06-27 2009-07-22 Health Research, Inc. Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy
AU2003249742A1 (en) * 2002-07-02 2004-01-23 Health Research, Inc. Efficient synthesis of pyropheophorbide a and its derivatives
CA2513133A1 (en) * 2003-01-16 2004-07-29 Techno Mart Co., Ltd. Porphyrin derivatives
US7057100B2 (en) * 2003-06-26 2006-06-06 The J.C. Robinson Seed Co. Inbred corn line W23129
GB0323358D0 (en) * 2003-10-06 2003-11-05 Green Grass Design Ltd Novel compounds and processes
JP4635493B2 (ja) * 2003-10-09 2011-02-23 日本製紙株式会社 ダル調塗工紙
GB2408265A (en) * 2003-11-21 2005-05-25 Univ Sheffield Water-soluble hyperbranched polymer porphyrins
US6995260B2 (en) * 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
EP1848778B1 (en) * 2005-02-18 2013-04-10 North Carolina State University De novo synthesis of bacteriochlorins
WO2007064841A2 (en) * 2005-11-30 2007-06-07 North Carolina State University Porphyrinic compounds for use in flow cytometry
WO2009038659A2 (en) * 2007-09-14 2009-03-26 Health Research, Inc. Organically modified silica nanoparticles with covalently incorporated photosensitizers for drug delivery in photodynamic therapy
US8253725B2 (en) * 2007-12-28 2012-08-28 St. Jude Medical, Atrial Fibrillation Division, Inc. Method and system for generating surface models of geometric structures
US20120034155A1 (en) * 2010-08-03 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Artificial cells
EP2350058B1 (en) * 2008-09-18 2018-10-24 biolitec Unternehmensbeteiligungs II AG Novel method and application of unsymmetrically meso-substituted porphyrins and chlorins for pdt
GB0819594D0 (en) 2008-10-24 2008-12-03 Univ Coimbrra Process
JP5988584B2 (ja) 2008-12-16 2016-09-07 キュー エル ティー インク．ＱＬＴ Ｉｎｃ． 眼の状態に関する光線力学的療法
US9211283B2 (en) 2009-12-11 2015-12-15 Biolitec Pharma Marketing Ltd Nanoparticle carrier systems based on human serum albumin for photodynamic therapy
CN102844044B (zh) 2010-02-04 2016-10-26 摩尔弗泰克有限公司 氯毒素多肽和结合物及其应用
CN103097390B (zh) * 2010-07-22 2017-03-08 拜欧利泰克投资二代公司 β‑官能化二羟基‑二氢卟酚用于PDT的应用
WO2013003507A1 (en) 2011-06-27 2013-01-03 Morphotek, Inc. Multifunctional agents
JP6181059B2 (ja) 2011-10-25 2017-08-16 メモリアル スローン−ケタリング キャンサー センター 前立腺がんのための診断薬、予後判定薬、および治療薬としてのフリーｐｓａ抗体
EP2911666B1 (en) 2012-10-26 2022-08-24 Memorial Sloan-Kettering Cancer Center Modulators of resistant androgen receptor
CN105377862B (zh) 2013-03-15 2019-09-13 希瑞·安·麦克法兰 用作光动力化合物的金属基配合物及其用途
ES2741811T3 (es) 2013-12-23 2020-02-12 Memorial Sloan Kettering Cancer Center Métodos y composiciones para el tratamiento del cáncer utilizando agentes peptidos a base de ácido nucleico
TWI474536B (zh) 2014-07-01 2015-02-21 Nat Univ Chung Hsing 紫質光敏染料化合物以及染料敏化太陽能電池
EP3201201B1 (en) 2014-09-30 2022-01-26 biolitec unternehmensbeteiligungs II AG Specifically meso-substituted porphyrins and chlorins for photodynamic therapy
RU2615770C1 (ru) * 2015-12-21 2017-04-11 Общество с ограниченной ответственностью "Пермская химическая компания" Борированные производные фторированных бактериохлоринов и их металлокомплексов, обладающие противоопухолевой активностью
EP3548494A4 (en) 2016-12-05 2020-08-12 Salt and Light Pharmaceuticals Pty. Ltd. PHOTODYNAMIC THERAPEUTIC COMPOUNDS AND PHOTODYNAMIC TREATMENT METHODS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648485A (en) * 1994-10-26 1997-07-15 University Of British Columbia β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US6376483B1 (en) * 1999-05-27 2002-04-23 Miravant Pharmaceuticals, Inc. Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production

Also Published As

Publication number Publication date
EP0804439A1 (en) 1997-11-05
PT804439E (pt) 2004-02-27
KR970707129A (ko) 1997-12-01
PL182239B1 (pl) 2001-11-30
CA2199399C (en) 2004-02-24
CZ115597A3 (en) 1997-09-17
CN1043143C (zh) 1999-04-28
TW301648B (hu) 1997-04-01
FI971734A0 (fi) 1997-04-23
DK0804439T3 (da) 2004-02-02
NO971952D0 (no) 1997-04-25
AU3695195A (en) 1996-05-23
JPH10507766A (ja) 1998-07-28
DE69531795T2 (de) 2004-08-05
FI971734A (fi) 1997-04-23
US5831088A (en) 1998-11-03
US5648485A (en) 1997-07-15
CZ294496B6 (cs) 2005-01-12
NZ294203A (en) 1998-12-23
CA2199399A1 (en) 1996-05-09
WO1996013504A1 (en) 1996-05-09
NO308411B1 (no) 2000-09-11
AU704971B2 (en) 1999-05-13
ES2208701T3 (es) 2004-06-16
JP3228296B2 (ja) 2001-11-12
CN1161697A (zh) 1997-10-08
HU221102B1 (en) 2002-08-28
JP2001294589A (ja) 2001-10-23
ATE250064T1 (de) 2003-10-15
NO971952L (no) 1997-04-25
DE69531795D1 (de) 2003-10-23
EP0804439B1 (en) 2003-09-17
MX9703013A (es) 1997-07-31
PL319907A1 (en) 1997-09-01

Similar Documents

Publication Publication Date Title
HUT77008A (hu) Mezo-szubsztituált klorin, bakterioklorin, izobakterioklorin béta,béta'-hidroxi-származékai és eljárás béta,béta' helyeken nem szubsztituált tetrapirrol makrociklusos vegyületekből történő előállításukra
IL126339A0 (en) Taxol derivatives
CA2219659A1 (en) Rapamycin derivatives
AU6518596A (en) Process for producing organic nitrogen compounds, special organic nitrogen compounds and mixtures of such compounds and their use as fuel and lubricant additives
WO1997032885B1 (en) Synthesis of isoimide of chlorins and bacteriochlorins and their use for diagnosis and treatment of cancer
AU4454597A (en) Novel benzofuran-4-carboxamides
CA2335514A1 (en) Alkyl ether analogs of chlorins having an n-substituted imide ring
AU3215795A (en) Indole alkaloids useful as uv protective and anti-inflammatory agents
PL309402A1 (en) Novel steroides
EP0822194A4 (en) ANNELLLIED IMIDAZO [1,2-a] PYRIDINE
CA2255664A1 (en) Selenophene anti-tumor agents
ES2173464T3 (es) Preparacion de clorinas y bacterioclorinas con contenido en polieter.
CA2277951A1 (en) Imino-aza-anthracyclinone derivatives
ES8609331A1 (es) Un procedimiento para preparar 2-bencil-7,7-dimetil-6,8- dioxa-2-espiro(3,5)nonano
ES2070790A1 (es) Derivados de carbapenem 1-beta-metil-2-tiolicos.
AU2407384A (en) Azirino(2'3':3,4)pyrrolo(1,2-a) indole-4,7-dione carbamate derivatives
IT1254201B (it) Procedimento per la preparazione di derivati del glicerolo otticamente attivi.
GB2001956A (en) 5,6,7-Trimethoxy naphthalene-(2)- carboxylic acid and hydronaphthalene-(2)- carboxylic acid derivatives
CA2207443A1 (en) Tricyclic compounds
AU6482694A (en) Recirculation of fuel
WO2000053580A3 (en) N-protected synthesis method for use in making porphyrins

Legal Events

Date Code Title Description
MM4A Lapse of definitive patent protection due to non-payment of fees