ES2173464T3 - Preparacion de clorinas y bacterioclorinas con contenido en polieter. - Google Patents

Preparacion de clorinas y bacterioclorinas con contenido en polieter.

Info

Publication number
ES2173464T3
ES2173464T3 ES97931715T ES97931715T ES2173464T3 ES 2173464 T3 ES2173464 T3 ES 2173464T3 ES 97931715 T ES97931715 T ES 97931715T ES 97931715 T ES97931715 T ES 97931715T ES 2173464 T3 ES2173464 T3 ES 2173464T3
Authority
ES
Spain
Prior art keywords
pct
polyether
preparation
bacterioclorins
polyeter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97931715T
Other languages
English (en)
Inventor
Hannsjorg Sinn
Hans-Hermann Schrenk
Michael Kaus
Wolfgang Maier-Borst
Gerd Stehle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deutsches Krebsforschungszentrum DKFZ
Original Assignee
Deutsches Krebsforschungszentrum DKFZ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforschungszentrum DKFZ filed Critical Deutsches Krebsforschungszentrum DKFZ
Application granted granted Critical
Publication of ES2173464T3 publication Critical patent/ES2173464T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCION TRATA DE UN PROCEDIMIENTO PARA LA OBTENCION DE CLORINAS Y/O BACTERIOCLORINAS QUE TIENEN UN POLIETER, QUE COMPRENDE LOS SIGUIENTES PASOS: (A) UNION DE UN POLIETER EN UNA PORFIRINA, Y (B) REACCION DE LA PORFIRINA QUE CONTIENE EL POLIETER CON UN REDUCTOR. TAMBIEN TRATA LA INVENCION DE LAS CLORINAS Y BACTERIOCLORINAS QUE CONTIENEN UN POLIETER Y QUE SE HAN OBTENIDO POR EL PROCEDIMIENTO Y DE SU UTILIZACION PARA LA TERAPIA FOTODINAMICA DE TUMORES.
ES97931715T 1996-07-05 1997-07-04 Preparacion de clorinas y bacterioclorinas con contenido en polieter. Expired - Lifetime ES2173464T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19627164A DE19627164C2 (de) 1996-07-05 1996-07-05 Herstellung polyether-aufweisender Chlorine und Bakteriochlorine, solche Verbindungen und ihre Verwendung

Publications (1)

Publication Number Publication Date
ES2173464T3 true ES2173464T3 (es) 2002-10-16

Family

ID=7799056

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97931715T Expired - Lifetime ES2173464T3 (es) 1996-07-05 1997-07-04 Preparacion de clorinas y bacterioclorinas con contenido en polieter.

Country Status (8)

Country Link
US (1) US6147207A (es)
EP (1) EP0909182B1 (es)
JP (1) JP2000514067A (es)
AT (1) ATE213419T1 (es)
DE (2) DE19627164C2 (es)
DK (1) DK0909182T3 (es)
ES (1) ES2173464T3 (es)
WO (1) WO1998001156A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19814405C2 (de) * 1998-03-31 2000-03-02 Schastak Astrid Porphyrine und ihre Verwendung als Photosensitizer
ES2237146T3 (es) 1998-08-28 2005-07-16 Destiny Pharma Limited Derivados de porfirina, su uso en terapia fotodinamica y dispositivos medicos que los contienen.
GB0005855D0 (en) * 2000-03-10 2000-05-03 Scotia Holdings Plc Compounds for pdt
US6559374B2 (en) * 2000-07-21 2003-05-06 North Carolina State University Trans beta substituted chlorins and methods of making and using the same
US6949581B2 (en) * 2003-03-21 2005-09-27 Ceramoptec Industries, Inc. Water-soluble mono-PEGylated tetrapyrrole derivatives for photodynamic therapy and method of production
ES2301424B1 (es) 2007-03-30 2009-02-01 Breat, S.L Procedimiento y su correspondiente dispositivo para la fabricacion de panales para apicultura.
US10570915B2 (en) 2014-02-19 2020-02-25 United Technologies Corporation Gas turbine engine airfoil

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5238940A (en) * 1990-03-22 1993-08-24 Quadra Logic Technologies Inc. Compositions for photodynamic therapy
DE4017439C2 (de) * 1990-05-30 1994-06-23 Deutsches Krebsforsch Polyethersubstituierte Tumormittel
US5149801A (en) * 1990-11-21 1992-09-22 The Regents Of The University Of California Boronated porphyrin compounds
US6362175B1 (en) * 1991-09-20 2002-03-26 The Trustees Of The University Of Pennsylvania Porphyrin compounds for imaging tissue oxygen
GB9408746D0 (en) * 1994-05-03 1994-06-22 Scotia Holdings Plc Tumour locallising photosensitising compounds
DE4435087A1 (de) * 1994-09-30 1996-04-04 Deutsches Krebsforsch Konjugat zur Behandlung von Infektions-, Autoimmun- und Hauterkrankungen

Also Published As

Publication number Publication date
DE19627164A1 (de) 1998-01-08
DE19627164C2 (de) 1998-09-24
WO1998001156A3 (de) 1998-04-09
WO1998001156A2 (de) 1998-01-15
DE59706440D1 (de) 2002-03-28
EP0909182A2 (de) 1999-04-21
EP0909182B1 (de) 2002-02-20
JP2000514067A (ja) 2000-10-24
US6147207A (en) 2000-11-14
DK0909182T3 (da) 2002-06-10
ATE213419T1 (de) 2002-03-15

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