PT804439E - Clorinas isobacterioclorinas bacterioclorinas beta,beta'-di-hidroxi meso-substituidas e metodos para fabricar as mesmas a partir de macrociclos tetrapirrolicos beta-beta'-nao substituidos - Google Patents

Clorinas isobacterioclorinas bacterioclorinas beta,beta'-di-hidroxi meso-substituidas e metodos para fabricar as mesmas a partir de macrociclos tetrapirrolicos beta-beta'-nao substituidos

Info

Publication number
PT804439E
PT804439E PT95944791T PT95944791T PT804439E PT 804439 E PT804439 E PT 804439E PT 95944791 T PT95944791 T PT 95944791T PT 95944791 T PT95944791 T PT 95944791T PT 804439 E PT804439 E PT 804439E
Authority
PT
Portugal
Prior art keywords
beta
substituted
tetrapyrolic
macrocycles
chemicals
Prior art date
Application number
PT95944791T
Other languages
English (en)
Inventor
David Dolphin
Christian Bruckner
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Publication of PT804439E publication Critical patent/PT804439E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
PT95944791T 1994-10-26 1995-10-25 Clorinas isobacterioclorinas bacterioclorinas beta,beta'-di-hidroxi meso-substituidas e metodos para fabricar as mesmas a partir de macrociclos tetrapirrolicos beta-beta'-nao substituidos PT804439E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/329,577 US5648485A (en) 1994-10-26 1994-10-26 β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins

Publications (1)

Publication Number Publication Date
PT804439E true PT804439E (pt) 2004-02-27

Family

ID=23286058

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95944791T PT804439E (pt) 1994-10-26 1995-10-25 Clorinas isobacterioclorinas bacterioclorinas beta,beta'-di-hidroxi meso-substituidas e metodos para fabricar as mesmas a partir de macrociclos tetrapirrolicos beta-beta'-nao substituidos

Country Status (20)

Country Link
US (2) US5648485A (pt)
EP (1) EP0804439B1 (pt)
JP (2) JP3228296B2 (pt)
KR (1) KR970707129A (pt)
CN (1) CN1043143C (pt)
AT (1) ATE250064T1 (pt)
AU (1) AU704971B2 (pt)
CA (1) CA2199399C (pt)
CZ (1) CZ294496B6 (pt)
DE (1) DE69531795T2 (pt)
DK (1) DK0804439T3 (pt)
ES (1) ES2208701T3 (pt)
FI (1) FI971734A0 (pt)
HU (1) HU221102B1 (pt)
NO (1) NO308411B1 (pt)
NZ (1) NZ294203A (pt)
PL (1) PL182239B1 (pt)
PT (1) PT804439E (pt)
TW (1) TW301648B (pt)
WO (1) WO1996013504A1 (pt)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648485A (en) * 1994-10-26 1997-07-15 University Of British Columbia β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
GB9610967D0 (en) 1996-05-24 1996-07-31 Cambridge Antibody Tech Specific binding members,materials and methods
EP0973383A4 (en) * 1997-01-21 2001-08-22 American Nat Red Cross INTRACELLULAR AND EXTRACELLULAR DECONTAMINATION OF WHOLE BLOOD AND BLOOD COMPONENTS WITH AMPHIPHILEN PHENOTHIAZINE-5-IUM DYES AND LIGHT
WO2000000204A1 (en) 1997-02-14 2000-01-06 Miravant Pharmaceuticals, Inc. Indium photosensitizers for pdt
FR2760841B1 (fr) * 1997-03-12 1999-04-16 Commissariat Energie Atomique Determination par resonance magnetique nucleaire de la configuration absolue d'amino-acides ou de leur derives et complexes metalliques de porphyrines chirales utilisables pour cette determination
DE19814405C2 (de) * 1998-03-31 2000-03-02 Schastak Astrid Porphyrine und ihre Verwendung als Photosensitizer
US20030176663A1 (en) * 1998-05-11 2003-09-18 Eidgenossische Technische Hochscule Specific binding molecules for scintigraphy
ID28751A (id) 1998-10-20 2001-06-28 Procter & Gamble Detergen pencuci yang mengandung alkilbenzena sulfonat termodifikasi
ES2260941T3 (es) 1998-10-20 2006-11-01 THE PROCTER & GAMBLE COMPANY Detergentes para la ropa que comprenden alquilbenceno sulfonatos modificados.
AU4139600A (en) 1999-04-14 2000-11-14 University Of British Columbia, The 1,3-dipolar cycloadditions to polypyrrolic macrocycles
US7022843B1 (en) 1999-04-14 2006-04-04 The University Of British Columbia β,β′-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US20020022032A1 (en) * 1999-04-23 2002-02-21 Curry Patrick Mark Immuno-adjuvant PDT treatment of metastatic tumors
US6376483B1 (en) 1999-05-27 2002-04-23 Miravant Pharmaceuticals, Inc. Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production
US7897140B2 (en) * 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
EP1259548A1 (en) 2000-02-24 2002-11-27 Eidgenössische Technische Hochschule Zürich Antibody specific for the ed-b domain of fibronectin, conjugates comprising said antibody, and their use for the detection and treatment of angiogenesis
US7282215B2 (en) 2000-05-08 2007-10-16 The University Of British Columbia Supports for photosensitizer formulations
WO2001085212A2 (en) 2000-05-08 2001-11-15 The University Of British Columbia Drug delivery systems for photodynamic therapy
US6559374B2 (en) * 2000-07-21 2003-05-06 North Carolina State University Trans beta substituted chlorins and methods of making and using the same
ES2312478T3 (es) * 2000-09-07 2009-03-01 Bayer Schering Pharma Aktiengesellschaft Receptor del dominio edb de fibronectina (ii).
WO2002020536A1 (fr) * 2000-09-08 2002-03-14 San-Ei Gen F.F.I.,Inc. Derives de tetraphenyl-bacteriochlore et compositions les contenant
JP2005513001A (ja) * 2001-11-09 2005-05-12 キュー エル ティー インク． 脱毛治療のための光力学療法
DE60328496D1 (en) 2002-06-27 2009-09-03 Health Research Inc Fluorinierte chlorin und bacteriochlorin photosensitizer für fotodynamische therapie
EP1606291A2 (en) * 2002-07-02 2005-12-21 Health Research, Inc. Efficient synthesis of pyropheophorbide a and its dervatives
WO2004063200A1 (en) * 2003-01-16 2004-07-29 Techno Mart Co., Ltd Porphyrin derivatives
US7057100B2 (en) * 2003-06-26 2006-06-06 The J.C. Robinson Seed Co. Inbred corn line W23129
GB0323358D0 (en) * 2003-10-06 2003-11-05 Green Grass Design Ltd Novel compounds and processes
JP4635493B2 (ja) * 2003-10-09 2011-02-23 日本製紙株式会社 ダル調塗工紙
GB2408265A (en) * 2003-11-21 2005-05-25 Univ Sheffield Water-soluble hyperbranched polymer porphyrins
US6995260B2 (en) * 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
WO2006089122A2 (en) 2005-02-18 2006-08-24 North Carolina State University De novo synthesis of bacteriochlorins
WO2007064841A2 (en) * 2005-11-30 2007-06-07 North Carolina State University Porphyrinic compounds for use in flow cytometry
WO2009038659A2 (en) * 2007-09-14 2009-03-26 Health Research, Inc. Organically modified silica nanoparticles with covalently incorporated photosensitizers for drug delivery in photodynamic therapy
US8253725B2 (en) * 2007-12-28 2012-08-28 St. Jude Medical, Atrial Fibrillation Division, Inc. Method and system for generating surface models of geometric structures
US20120034157A1 (en) * 2010-08-03 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Artificial cells
EP2350058B1 (en) * 2008-09-18 2018-10-24 biolitec Unternehmensbeteiligungs II AG Novel method and application of unsymmetrically meso-substituted porphyrins and chlorins for pdt
GB0819594D0 (en) 2008-10-24 2008-12-03 Univ Coimbrra Process
JP5988584B2 (ja) 2008-12-16 2016-09-07 キュー エル ティー インク．ＱＬＴ Ｉｎｃ． 眼の状態に関する光線力学的療法
US9211283B2 (en) 2009-12-11 2015-12-15 Biolitec Pharma Marketing Ltd Nanoparticle carrier systems based on human serum albumin for photodynamic therapy
CN102844044B (zh) 2010-02-04 2016-10-26 摩尔弗泰克有限公司 氯毒素多肽和结合物及其应用
EP2870159B1 (en) * 2010-07-22 2017-06-28 biolitec Unternehmensbeteiligungs II AG APPLICATION OF ß-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT
WO2013003507A1 (en) 2011-06-27 2013-01-03 Morphotek, Inc. Multifunctional agents
CN106872702A (zh) 2011-10-25 2017-06-20 斯隆－凯特林纪念癌症中心 用于前列腺癌的诊断、预测和治疗的游离psa抗体
WO2014066799A2 (en) 2012-10-26 2014-05-01 Memorial Sloan-Kettering Cancer Center Modulators of resistant androgen receptor
CA2907356C (en) 2013-03-15 2022-07-12 Sherri Ann MCFARLAND Metal-based coordination complexes as photodynamic compounds and their use
EP3581653A3 (en) 2013-12-23 2020-02-19 Memorial Sloan-Kettering Cancer Center Methods and compositions for treating cancer using peptide nucleic acid-based agents
TWI474536B (zh) 2014-07-01 2015-02-21 Nat Univ Chung Hsing 紫質光敏染料化合物以及染料敏化太陽能電池
WO2016051361A1 (en) 2014-09-30 2016-04-07 Biolitec Unternehmensbeteiligungs Ii Ag Specifically meso-substituted porphyrins and chlorins for photodynamic therapy
RU2615770C1 (ru) * 2015-12-21 2017-04-11 Общество с ограниченной ответственностью "Пермская химическая компания" Борированные производные фторированных бактериохлоринов и их металлокомплексов, обладающие противоопухолевой активностью
EP3548494A4 (en) * 2016-12-05 2020-08-12 Salt and Light Pharmaceuticals Pty. Ltd. PHOTODYNAMIC THERAPEUTIC COMPOUNDS AND PHOTODYNAMIC TREATMENT METHODS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648485A (en) * 1994-10-26 1997-07-15 University Of British Columbia β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US6376483B1 (en) * 1999-05-27 2002-04-23 Miravant Pharmaceuticals, Inc. Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production

Also Published As

Publication number Publication date
TW301648B (pt) 1997-04-01
MX9703013A (es) 1997-07-31
NZ294203A (en) 1998-12-23
AU3695195A (en) 1996-05-23
JP2001294589A (ja) 2001-10-23
KR970707129A (ko) 1997-12-01
ATE250064T1 (de) 2003-10-15
EP0804439A1 (en) 1997-11-05
FI971734A (fi) 1997-04-23
FI971734A0 (fi) 1997-04-23
US5648485A (en) 1997-07-15
CN1161697A (zh) 1997-10-08
CN1043143C (zh) 1999-04-28
JPH10507766A (ja) 1998-07-28
CA2199399A1 (en) 1996-05-09
HU221102B1 (en) 2002-08-28
CZ115597A3 (en) 1997-09-17
PL182239B1 (pl) 2001-11-30
US5831088A (en) 1998-11-03
NO971952L (no) 1997-04-25
EP0804439B1 (en) 2003-09-17
WO1996013504A1 (en) 1996-05-09
DE69531795T2 (de) 2004-08-05
PL319907A1 (en) 1997-09-01
CZ294496B6 (cs) 2005-01-12
ES2208701T3 (es) 2004-06-16
JP3228296B2 (ja) 2001-11-12
AU704971B2 (en) 1999-05-13
DE69531795D1 (de) 2003-10-23
HUT77008A (hu) 1998-03-02
NO308411B1 (no) 2000-09-11
CA2199399C (en) 2004-02-24
NO971952D0 (no) 1997-04-25
DK0804439T3 (da) 2004-02-02

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