DK0804173T3 - Biologisk nedbrydelige mikrokugler med kontrolleret frigivelse og fremgangsmåde til fremstilling heraf - Google Patents

Biologisk nedbrydelige mikrokugler med kontrolleret frigivelse og fremgangsmåde til fremstilling heraf

Info

Publication number
DK0804173T3
DK0804173T3 DK95917394T DK95917394T DK0804173T3 DK 0804173 T3 DK0804173 T3 DK 0804173T3 DK 95917394 T DK95917394 T DK 95917394T DK 95917394 T DK95917394 T DK 95917394T DK 0804173 T3 DK0804173 T3 DK 0804173T3
Authority
DK
Denmark
Prior art keywords
pct
microspheres
active ingredient
date oct
preparation
Prior art date
Application number
DK95917394T
Other languages
English (en)
Inventor
Rosa Arola
Miguel Angel Asin
Eulalia Ferret
Eric Goutay
Amadeo Perez
Pere Tarin
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Application granted granted Critical
Publication of DK0804173T3 publication Critical patent/DK0804173T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK95917394T 1994-04-15 1995-04-13 Biologisk nedbrydelige mikrokugler med kontrolleret frigivelse og fremgangsmåde til fremstilling heraf DK0804173T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9404511A FR2718642B1 (fr) 1994-04-15 1994-04-15 Microsphères biodégradables à libération contrôlée et leur procédé de préparation.
PCT/FR1995/000485 WO1995028149A1 (fr) 1994-04-15 1995-04-13 Microspheres biodegradables a liberation controlee et leur procede de preparation

Publications (1)

Publication Number Publication Date
DK0804173T3 true DK0804173T3 (da) 1999-07-12

Family

ID=9462140

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95917394T DK0804173T3 (da) 1994-04-15 1995-04-13 Biologisk nedbrydelige mikrokugler med kontrolleret frigivelse og fremgangsmåde til fremstilling heraf

Country Status (11)

Country Link
US (1) US5733567A (da)
EP (1) EP0804173B1 (da)
JP (1) JP4073478B2 (da)
AT (1) ATE172639T1 (da)
AU (1) AU698796B2 (da)
CA (1) CA2187898C (da)
DE (1) DE69505697T2 (da)
DK (1) DK0804173T3 (da)
FR (1) FR2718642B1 (da)
NZ (1) NZ284826A (da)
WO (1) WO1995028149A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19545257A1 (de) 1995-11-24 1997-06-19 Schering Ag Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln
JP2002512597A (ja) * 1996-12-20 2002-04-23 アルザ コーポレイション 注射可能な貯留槽ゲル組成物およびこの組成物の製造方法
EP1009386B1 (en) * 1997-08-29 2005-08-31 Corixa Corporation Rapid release encapsulated bioactive agents for inducing or potentiating an immune response and methods of using thereof
KR19990085365A (ko) * 1998-05-16 1999-12-06 허영섭 지속적으로 약물 조절방출이 가능한 생분해성 고분자 미립구 및그 제조방법
US20030211974A1 (en) * 2000-03-21 2003-11-13 Brodbeck Kevin J. Gel composition and methods
AR023940A1 (es) 2000-05-03 2002-09-04 Eriochem Sa Procedimiento para la produccion de microcapsulas de liberacion prolongada de peptidos solubles en agua
CN1189159C (zh) 2000-05-05 2005-02-16 欧莱雅 含水溶性美容活性组分水性核的微胶囊及含其的组合物
US6565888B1 (en) 2000-08-23 2003-05-20 Alkermes Controlled Therapeutics, Inc. Methods and compositions for the targeted delivery of biologically active agents
US7252842B2 (en) 2000-12-21 2007-08-07 Alrise Biosystems Gmbh Induced phase transition method for the production of microparticles containing hydrophilic active agents
CA2451187C (en) 2001-06-22 2012-08-14 Southern Biosystems, Inc. Zero-order prolonged release coaxial implants
FR2830448B1 (fr) * 2001-10-10 2004-03-19 Pf Medicament Microspheres biodegradables a liberation prolongee et leur procede de preparation
EP1450766B1 (fr) 2001-10-10 2015-04-22 Pierre Fabre Medicament Microspheres biodegradables a liberation prolongee et leur procede de preparation
ES2194590B2 (es) * 2001-10-10 2006-02-16 Pierre Fabre Iberica S.A. Microesferas biodegradables con liberacion prolongada y su procedimiento de preparacion.
US7235488B2 (en) * 2002-08-28 2007-06-26 Micron Technology, Inc. In-situ chemical-mechanical planarization pad metrology using ultrasonic imaging
US8986737B2 (en) * 2002-09-05 2015-03-24 Wm. Marsh Rice University Antibiotic microspheres for treatment and prevention of osteomyelitis and enhancement of bone regrowth
WO2004022000A2 (en) * 2002-09-05 2004-03-18 Ambrose Catherine G Antibiotic microspheres for treatment of infections and osteomyelitis
CN1323096C (zh) * 2005-05-26 2007-06-27 中国科学院长春应用化学研究所 生物可降解聚酯微粒及其制备方法和用途
US9693967B2 (en) * 2005-09-07 2017-07-04 Southwest Research Institute Biodegradable microparticle pharmaceutical formulations exhibiting improved released rates
US20070106271A1 (en) * 2005-11-09 2007-05-10 Searete Llc, A Limited Liability Corporation Remote control of substance delivery system
CA2709712C (en) * 2007-12-20 2016-05-10 Surmodics Pharmaceuticals, Inc. Process for preparing microparticles having a low residual solvent volume
US20150328377A1 (en) * 2012-12-31 2015-11-19 Bacterin International, Inc. Composition of d-alpha hydroxy acids and antimicrobials

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5389377A (en) * 1989-12-22 1995-02-14 Molecular Bioquest, Inc. Solid care therapeutic compositions and methods for making same
ZA918168B (en) * 1990-10-16 1993-04-14 Takeda Chemical Industries Ltd Prolonged release preparation and polymers thereof.
WO1993000156A1 (fr) * 1991-06-29 1993-01-07 Miyazaki-Ken Emulsions monodispersees simples et doubles et procede de production
JP3051945B2 (ja) * 1991-07-22 2000-06-12 大阪瓦斯株式会社 無機質均一微小球体、及びその製造方法
ES2181691T5 (es) * 1992-06-11 2007-10-01 Alkermes Controlled Therapeutics, Inc. Sistema de distribucion de proteina eritropoyetina.
FR2692147B1 (fr) * 1992-06-15 1995-02-24 Centre Nat Rech Scient Microsphères en polymère biorésorbable exemptes de tensioactif, leur préparation et leur application comme médicament.

Also Published As

Publication number Publication date
DE69505697D1 (de) 1998-12-03
JPH09512002A (ja) 1997-12-02
EP0804173B1 (fr) 1998-10-28
FR2718642A1 (fr) 1995-10-20
WO1995028149A1 (fr) 1995-10-26
FR2718642B1 (fr) 1996-07-12
CA2187898C (fr) 2005-08-23
EP0804173A1 (fr) 1997-11-05
CA2187898A1 (fr) 1995-10-26
AU698796B2 (en) 1998-11-05
NZ284826A (en) 1997-12-19
DE69505697T2 (de) 1999-06-10
JP4073478B2 (ja) 2008-04-09
US5733567A (en) 1998-03-31
ATE172639T1 (de) 1998-11-15
AU2347895A (en) 1995-11-10

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