DK0775159T3 - Ny fremgangsmåde til fremstilling af biologisk aktivt dimert protein - Google Patents

Ny fremgangsmåde til fremstilling af biologisk aktivt dimert protein

Info

Publication number
DK0775159T3
DK0775159T3 DK95926857T DK95926857T DK0775159T3 DK 0775159 T3 DK0775159 T3 DK 0775159T3 DK 95926857 T DK95926857 T DK 95926857T DK 95926857 T DK95926857 T DK 95926857T DK 0775159 T3 DK0775159 T3 DK 0775159T3
Authority
DK
Denmark
Prior art keywords
biologically active
new method
dimeric protein
producing biologically
active dimeric
Prior art date
Application number
DK95926857T
Other languages
Danish (da)
English (en)
Inventor
Nico Cerletti
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK0775159T3 publication Critical patent/DK0775159T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/495Transforming growth factor [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Saccharide Compounds (AREA)
DK95926857T 1994-07-25 1995-07-12 Ny fremgangsmåde til fremstilling af biologisk aktivt dimert protein DK0775159T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94810438 1994-07-25
PCT/EP1995/002718 WO1996003432A1 (en) 1994-07-25 1995-07-12 Novel process for the production of biologically active dimeric protein

Publications (1)

Publication Number Publication Date
DK0775159T3 true DK0775159T3 (da) 2002-02-11

Family

ID=8218292

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95926857T DK0775159T3 (da) 1994-07-25 1995-07-12 Ny fremgangsmåde til fremstilling af biologisk aktivt dimert protein

Country Status (19)

Country Link
US (1) US6057430A (ja)
EP (1) EP0775159B1 (ja)
JP (2) JP3923516B2 (ja)
KR (1) KR100432839B1 (ja)
AT (1) ATE207933T1 (ja)
AU (1) AU690311B2 (ja)
CA (1) CA2194582C (ja)
DE (1) DE69523605T2 (ja)
DK (1) DK0775159T3 (ja)
ES (1) ES2166401T3 (ja)
FI (1) FI118083B (ja)
HU (1) HU222830B1 (ja)
IL (1) IL114701A (ja)
NO (1) NO316926B1 (ja)
NZ (1) NZ290373A (ja)
PT (1) PT775159E (ja)
TW (1) TW440566B (ja)
WO (1) WO1996003432A1 (ja)
ZA (1) ZA956138B (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW517059B (en) * 1994-07-25 2003-01-11 Ciba Geigy Ag New process for the production of biologically active protein
US6084076A (en) * 1995-12-21 2000-07-04 Ajinomoto Co., Inc. Method of refolding human activin A
DE19906096A1 (de) 1999-02-13 2000-08-17 Walter Sebald Protein mit einem Heparin-bindenden Epitop
EP1273655A4 (en) * 2000-03-30 2004-08-04 Takeda Chemical Industries Ltd METHOD FOR PRODUCING A RECOMBINANT PROTEIN
AU2001246393A1 (en) * 2000-03-31 2001-10-08 Vaccine Chip Technology Aps Immunostimulating properties of a fragment of tgf-beta
US7572474B2 (en) 2005-06-01 2009-08-11 Mead Johnson Nutrition Company Method for simulating the functional attributes of human milk oligosaccharides in formula-fed infants
US8075934B2 (en) * 2008-10-24 2011-12-13 Mead Johnson Nutrition Company Nutritional composition with improved digestibility
GB0514262D0 (en) * 2005-07-12 2005-08-17 Renovo Ltd Promotion of epithelial regeneration
GB0604938D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Proteins, nucleic acids and medicaments
GB0604966D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Medicaments and proteins
GB0604964D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Protein folding
GB0617816D0 (en) * 2006-09-11 2006-10-18 Renovo Ltd Nucleic acids and methods of protein expression
US8986769B2 (en) 2008-10-24 2015-03-24 Mead Johnson Nutrition Company Methods for preserving endogenous TGF-β
WO2018122794A1 (en) 2016-12-30 2018-07-05 Biogend Therapeutics Co., Ltd. Recombinant polypeptides and nucleic acid molecules, compositions, and methods of making and uses thereof
CN113348000A (zh) * 2018-09-17 2021-09-03 德克萨斯大学体系董事会 用于治疗骨损伤的组合物和方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4731440A (en) * 1985-02-22 1988-03-15 Monsanto Company Method of somatotropin solubilization using dimethylsulfone and naturation
JPH0759598B2 (ja) * 1986-02-14 1995-06-28 藤沢薬品工業株式会社 ヒトインスリン様成長因子▲i▼の製造法
EP0293785A3 (en) * 1987-05-29 1990-05-02 Oncogen Limited Partnership Cloning and expression of simian transforming growth factor-ss1
US5061786A (en) * 1989-05-25 1991-10-29 Genentech, Inc. Biologically active polypeptides based on transforming growth factor-β
GB8927546D0 (en) * 1989-12-06 1990-02-07 Ciba Geigy Process for the production of biologically active tgf-beta
US5144006A (en) * 1991-06-13 1992-09-01 The Rockefeller University Oxidative folding of peptide and protein substrates using hydrocarbon sulfoxides
AU2738392A (en) * 1991-11-11 1993-05-13 Ciba-Geigy Ag Novel hybrid transforming growth factors

Also Published As

Publication number Publication date
NO970325L (no) 1997-03-06
CA2194582C (en) 2008-09-02
FI970229A (fi) 1997-01-20
ATE207933T1 (de) 2001-11-15
HUT76668A (en) 1997-10-28
FI970229A0 (fi) 1997-01-20
ZA956138B (en) 1996-03-07
AU3109595A (en) 1996-02-22
HU222830B1 (hu) 2003-11-28
JP3923516B2 (ja) 2007-06-06
EP0775159B1 (en) 2001-10-31
ES2166401T3 (es) 2002-04-16
CA2194582A1 (en) 1996-02-08
US6057430A (en) 2000-05-02
JPH11505506A (ja) 1999-05-21
PT775159E (pt) 2002-04-29
DE69523605D1 (de) 2001-12-06
IL114701A0 (en) 1995-11-27
WO1996003432A1 (en) 1996-02-08
FI118083B (fi) 2007-06-29
KR100432839B1 (ko) 2004-08-30
NO970325D0 (no) 1997-01-24
NO316926B1 (no) 2004-06-28
JP2007031453A (ja) 2007-02-08
TW440566B (en) 2001-06-16
AU690311B2 (en) 1998-04-23
EP0775159A1 (en) 1997-05-28
DE69523605T2 (de) 2002-07-11
IL114701A (en) 2005-11-20
NZ290373A (en) 1998-04-27

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