NO20003131L - Krystallinsk teriparatid - Google Patents

Krystallinsk teriparatid

Info

Publication number
NO20003131L
NO20003131L NO20003131A NO20003131A NO20003131L NO 20003131 L NO20003131 L NO 20003131L NO 20003131 A NO20003131 A NO 20003131A NO 20003131 A NO20003131 A NO 20003131A NO 20003131 L NO20003131 L NO 20003131L
Authority
NO
Norway
Prior art keywords
teriparatide
crystalline
purification
pure
preparation
Prior art date
Application number
NO20003131A
Other languages
English (en)
Other versions
NO20003131D0 (no
Inventor
Faming Zhang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO20003131L publication Critical patent/NO20003131L/no
Publication of NO20003131D0 publication Critical patent/NO20003131D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)

Abstract

Rene, stabile krystallinske former av parathyroidhormon, særlig teriparatid, er beskrevet så vel som fremgangsmåter for fremstilling og rensing.
NO20003131A 1997-12-18 2000-06-16 Krystallinsk teriparatid NO20003131D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6987597P 1997-12-18 1997-12-18
PCT/US1998/026044 WO1999031137A1 (en) 1997-12-18 1998-12-08 Crystalline teriparatide

Publications (2)

Publication Number Publication Date
NO20003131L true NO20003131L (no) 2000-06-16
NO20003131D0 NO20003131D0 (no) 2000-06-16

Family

ID=22091750

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003131A NO20003131D0 (no) 1997-12-18 2000-06-16 Krystallinsk teriparatid

Country Status (24)

Country Link
US (1) US6590081B1 (no)
EP (1) EP0926158B1 (no)
JP (1) JP2002508395A (no)
KR (1) KR20010033268A (no)
CN (1) CN1281467A (no)
AR (1) AR038648A1 (no)
AT (1) ATE245165T1 (no)
AU (1) AU748271B2 (no)
BR (1) BR9813740A (no)
CA (1) CA2315103A1 (no)
DE (1) DE69816409T2 (no)
DK (1) DK0926158T3 (no)
EA (1) EA200000672A1 (no)
ES (1) ES2202729T3 (no)
HU (1) HUP0100075A2 (no)
ID (1) ID25660A (no)
IL (1) IL136824A0 (no)
NO (1) NO20003131D0 (no)
PE (1) PE20000056A1 (no)
PL (1) PL341209A1 (no)
PT (1) PT926158E (no)
TR (1) TR200002179T2 (no)
WO (1) WO1999031137A1 (no)
ZA (1) ZA9811407B (no)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7601685B2 (en) 1998-08-27 2009-10-13 Eidgenossische Technische Hochschule Zurich Growth factor modified protein matrices for tissue engineering
MXPA04006021A (es) * 2001-12-18 2005-08-19 Eth Zuerich Matrices de proteina modificada con factor de crecimiento para ingenieria de tejidos.
US7247609B2 (en) 2001-12-18 2007-07-24 Universitat Zurich Growth factor modified protein matrices for tissue engineering
EP1864681A1 (en) 2001-12-18 2007-12-12 Eidgenössische Technische Hochschule Zürich Growth factor modified protein matrices for tissue engineering
AU2003278766A1 (en) * 2002-09-04 2004-03-29 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
SG176314A1 (en) 2002-12-31 2011-12-29 Altus Pharmaceuticals Inc Human growth hormone crystals and methods for preparing them
US8088734B2 (en) 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
US7553827B2 (en) * 2003-08-13 2009-06-30 Depuy Spine, Inc. Transdiscal administration of cycline compounds
US8273347B2 (en) 2003-05-13 2012-09-25 Depuy Spine, Inc. Autologous treatment of degenerated disc with cells
US7344716B2 (en) * 2003-05-13 2008-03-18 Depuy Spine, Inc. Transdiscal administration of specific inhibitors of pro-inflammatory cytokines
US20040229878A1 (en) * 2003-05-13 2004-11-18 Depuy Spine, Inc. Transdiscal administration of specific inhibitors of P38 kinase
US7429378B2 (en) * 2003-05-13 2008-09-30 Depuy Spine, Inc. Transdiscal administration of high affinity anti-MMP inhibitors
US8361467B2 (en) * 2003-07-30 2013-01-29 Depuy Spine, Inc. Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints
US8895540B2 (en) 2003-11-26 2014-11-25 DePuy Synthes Products, LLC Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
US20060052305A1 (en) * 2004-05-10 2006-03-09 Nastech Pharmaceutical Company Inc. Method of treating osteoporosis using intranasal parathyroid hormone
AU2005247369A1 (en) * 2004-05-10 2005-12-08 Mdrna, Inc. Compositions and methods for enhanced mucosal delivery of parathyroid hormone
US20060127320A1 (en) * 2004-05-10 2006-06-15 Nastech Pharmaceutical Company Inc. Method of delivering parathyroid hormone to a human
WO2005112984A2 (en) 2004-05-13 2005-12-01 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
WO2006073711A2 (en) 2005-01-06 2006-07-13 Kuros Biosurgery Ag Use of a matrix comprising a contrast agent in soft tissues
US7691105B2 (en) 2005-09-26 2010-04-06 Depuy Spine, Inc. Tissue augmentation, stabilization and regeneration technique
US20070088436A1 (en) 2005-09-29 2007-04-19 Matthew Parsons Methods and devices for stenting or tamping a fractured vertebral body
US20070173447A1 (en) * 2005-10-25 2007-07-26 Nastech Pharmaceutical Company Inc. Method for treating osteoporosis by intranasal delivery of teriparatide with an anti-resorptive agent
EP1945245A2 (en) * 2005-11-10 2008-07-23 The Board of Control of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US20080051332A1 (en) * 2005-11-18 2008-02-28 Nastech Pharmaceutical Company Inc. Method of modulating hematopoietic stem cells and treating hematologic diseases using intranasal parathyroid hormone
US20070168041A1 (en) * 2006-01-17 2007-07-19 Sudhakar Kadiyala Method and instruments for intervertebral disc augmentation through a pedicular approach
MX2009011005A (es) 2007-04-13 2009-11-02 Kuros Biosurgery Ag Sellador polimerico para tejido.
CA2694562A1 (en) * 2007-08-09 2009-02-12 Usv Limited Novel orthogonal process for purification of recombinant human parathyroid hormone (rhpth) (1-34)
US8741329B2 (en) * 2007-09-21 2014-06-03 Merck Sharp & Dohme B.V. Drug delivery system
US8241363B2 (en) 2007-12-19 2012-08-14 Depuy Spine, Inc. Expandable corpectomy spinal fusion cage
US8241294B2 (en) 2007-12-19 2012-08-14 Depuy Spine, Inc. Instruments for expandable corpectomy spinal fusion cage
US20090162351A1 (en) * 2007-12-21 2009-06-25 Depuy Spine, Inc. Transdiscal administration of inhibitors of p38 MAP kinase
US8986696B2 (en) * 2007-12-21 2015-03-24 Depuy Mitek, Inc. Trans-capsular administration of p38 map kinase inhibitors into orthopedic joints
JP2012512812A (ja) 2007-12-28 2012-06-07 クロス・バイオサージェリー・アクチェンゲゼルシャフト フィブリンフォームに組込まれたｐｄｇｆ融合タンパク質
US8876905B2 (en) 2009-04-29 2014-11-04 DePuy Synthes Products, LLC Minimally invasive corpectomy cage and instrument
AU2009356227A1 (en) 2009-12-07 2012-06-21 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US8865220B2 (en) 2010-06-14 2014-10-21 Kaohsiung Medical University Method for controlled release of parathyroid hormone from encapsulated poly(lactic-glycolic)acid microspheres
ES2882852T3 (es) 2011-03-16 2021-12-02 Kuros Biosurgery Ag Formulación farmacéutica para la utilización en la fusión espinal
CN102731643A (zh) * 2012-06-26 2012-10-17 深圳翰宇药业股份有限公司 一种治疗骨质疏松多肽的制备方法
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
EP3079659B1 (en) 2013-12-11 2020-10-28 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
CN104910269B (zh) * 2015-06-02 2018-08-17 成都圣诺生物科技股份有限公司 一种合成特立帕肽的方法
EP3685849A4 (en) * 2017-09-22 2021-12-22 Asahi Kasei Pharma Corporation LIQUID PHARMACEUTICAL COMPOSITION CONTAINING TRIPARATIDE WITH EXCELLENT STABILITY

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62106000A (ja) * 1985-10-30 1987-05-16 Fujitsu Ltd 生体高分子結晶自動作製装置
JP2802084B2 (ja) * 1987-10-20 1998-09-21 ホリック，マイケル・エフ ペプチドを用いた細胞の増殖と分化の調節
AU2764492A (en) * 1991-10-09 1993-05-03 Schering Corporation Crystal forming device and automated crystallization system
US5400741A (en) 1993-05-21 1995-03-28 Medical Foundation Of Buffalo, Inc. Device for growing crystals
US5496801A (en) * 1993-12-23 1996-03-05 Allelix Biopharmaceuticals Inc. Parathyroid hormone formulation
US5419278A (en) 1994-05-25 1995-05-30 Carter; Daniel C. Vapor equilibration tray for growing protein crystals
CA2178894A1 (en) * 1995-06-15 1996-12-16 Tsunehiko Fukuda Parathyroid hormone derivatives and their use

Also Published As

Publication number Publication date
PE20000056A1 (es) 2000-02-08
AR038648A1 (es) 2005-01-26
DK0926158T3 (da) 2003-11-10
DE69816409T2 (de) 2004-06-09
EP0926158A1 (en) 1999-06-30
AU748271B2 (en) 2002-05-30
JP2002508395A (ja) 2002-03-19
BR9813740A (pt) 2000-10-10
CA2315103A1 (en) 1999-06-24
AU1632699A (en) 1999-07-05
TR200002179T2 (tr) 2001-07-23
ZA9811407B (en) 2000-07-13
US6590081B1 (en) 2003-07-08
IL136824A0 (en) 2001-06-14
DE69816409D1 (de) 2003-08-21
NO20003131D0 (no) 2000-06-16
PL341209A1 (en) 2001-03-26
ATE245165T1 (de) 2003-08-15
EA200000672A1 (ru) 2000-12-25
ES2202729T3 (es) 2004-04-01
KR20010033268A (ko) 2001-04-25
PT926158E (pt) 2003-11-28
ID25660A (id) 2000-10-19
EP0926158B1 (en) 2003-07-16
HUP0100075A2 (hu) 2001-05-28
CN1281467A (zh) 2001-01-24
WO1999031137A1 (en) 1999-06-24

Similar Documents

Publication Publication Date Title
NO20003131L (no) Krystallinsk teriparatid
ATE346146T1 (de) Fibrinmikrokugeln und deren verwendungen
DK0813525T3 (da) Benzamidinderivater, deres fremstilling og anvendelse som antikoagulanter
NO20030374D0 (no) Syklopentanoindoler, preparater som inneholder slike forbindelser og behandlingsfremgangsmåter
DK0876332T3 (da) Phenyleddikesyrederivater, fremgangsmåde og mellemprodukter til deres fremstilling og midler indeholdende disse
DK0767798T3 (da) Sterolderivater anvendt til regulering af meiose
DK1036794T3 (da) 2-Aryl-8-oxodihydropurinderivater, fremgangsmåde til fremstilling af samme, medicinske præparater indeholdende samme og mellemprodukter deraf
ES2191292T3 (es) Compuestos antivirales poliaromaticos.
DE69911993D1 (de) Polyol/öl-suspensionen zur verzörgerten freisetzung von proteinen
DK1097173T3 (da) Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midler
YU58599A (sh) Gelovi sa usporenim podržanim oslobađanjem
DK1033990T3 (da) 21-Hydroxy-6,19-oxidoprogesteron (21OH-6OP) dets anvendelse som medikament i behandling af glucocorticoidoverskud
ES2158034T3 (es) Derivado de benzotiepina opticamente activo, su preparacion y uso.
ATE202483T1 (de) Immuntolerante prothrombinkomplex-präparation
DK0775159T3 (da) Ny fremgangsmåde til fremstilling af biologisk aktivt dimert protein
DK1154986T3 (da) Fremgangsmåde til fremstilling af iopamidol
ES2195483T3 (es) Concentrado acuoso para suspension, que contiene tidiazuron y etefon.
DK1427286T3 (da) Fremgangsmåde til udtynding af frugt
DK0795547T3 (da) (Aminoalkyl- og acylaminoalkyl-oxy)benzyloxyquinoliner, fremgangsmåde til deres fremstilling og deres anvendelse som bradyk
DK1303267T3 (da) System til dermal tilförsel af aminolevulinsyre
NO990914L (no) Amorfe benzotiofener, fremgangsmÕter for fremstilling og fremgangsmÕter for anvendelse
NZ503372A (en) Chemical supplementation of bone by exposing bone to a therapeutic compound and applying a potential difference across the bone or tissue
FI945164A (fi) Biologisesti aktiivisesti ureidojohdannaiset, jotka ovat käyttökelpoisia antimetastaattisina aineina
DK1068209T3 (da) Fremgangsmåde til fremstilling af purinderivater og deres mellemprodukter
DK0951561T3 (da) Enzymatiske fremgangsmåder til fremstilling af (S)-cyanhydriner

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application