ATE245165T1 - Kristallines parathyroidhormon - Google Patents

Kristallines parathyroidhormon

Info

Publication number
ATE245165T1
ATE245165T1 AT98123878T AT98123878T ATE245165T1 AT E245165 T1 ATE245165 T1 AT E245165T1 AT 98123878 T AT98123878 T AT 98123878T AT 98123878 T AT98123878 T AT 98123878T AT E245165 T1 ATE245165 T1 AT E245165T1
Authority
AT
Austria
Prior art keywords
crystalline
parathyroid hormone
parathyroid
hormone
crystalline parathyroid
Prior art date
Application number
AT98123878T
Other languages
English (en)
Inventor
Faming Zhang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE245165T1 publication Critical patent/ATE245165T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/635Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
AT98123878T 1997-12-18 1998-12-16 Kristallines parathyroidhormon ATE245165T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6987597P 1997-12-18 1997-12-18

Publications (1)

Publication Number Publication Date
ATE245165T1 true ATE245165T1 (de) 2003-08-15

Family

ID=22091750

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98123878T ATE245165T1 (de) 1997-12-18 1998-12-16 Kristallines parathyroidhormon

Country Status (24)

Country Link
US (1) US6590081B1 (de)
EP (1) EP0926158B1 (de)
JP (1) JP2002508395A (de)
KR (1) KR20010033268A (de)
CN (1) CN1281467A (de)
AR (1) AR038648A1 (de)
AT (1) ATE245165T1 (de)
AU (1) AU748271B2 (de)
BR (1) BR9813740A (de)
CA (1) CA2315103A1 (de)
DE (1) DE69816409T2 (de)
DK (1) DK0926158T3 (de)
EA (1) EA200000672A1 (de)
ES (1) ES2202729T3 (de)
HU (1) HUP0100075A2 (de)
ID (1) ID25660A (de)
IL (1) IL136824A0 (de)
NO (1) NO20003131D0 (de)
PE (1) PE20000056A1 (de)
PL (1) PL341209A1 (de)
PT (1) PT926158E (de)
TR (1) TR200002179T2 (de)
WO (1) WO1999031137A1 (de)
ZA (1) ZA9811407B (de)

Families Citing this family (43)

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US7601685B2 (en) 1998-08-27 2009-10-13 Eidgenossische Technische Hochschule Zurich Growth factor modified protein matrices for tissue engineering
MXPA04006021A (es) * 2001-12-18 2005-08-19 Eth Zuerich Matrices de proteina modificada con factor de crecimiento para ingenieria de tejidos.
EP1864681A1 (de) 2001-12-18 2007-12-12 Eidgenössische Technische Hochschule Zürich Wachstumsfaktormodifizierte Proteinmatrizes zur Geweberekonstruktion
US7247609B2 (en) 2001-12-18 2007-07-24 Universitat Zurich Growth factor modified protein matrices for tissue engineering
WO2004022033A1 (en) * 2002-09-04 2004-03-18 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
JP4686361B2 (ja) 2002-12-31 2011-05-25 アルタス ファーマシューティカルズ インコーポレイテッド ヒト成長ホルモンの結晶およびその調製方法
US8088734B2 (en) 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
US7429378B2 (en) * 2003-05-13 2008-09-30 Depuy Spine, Inc. Transdiscal administration of high affinity anti-MMP inhibitors
US8273347B2 (en) 2003-05-13 2012-09-25 Depuy Spine, Inc. Autologous treatment of degenerated disc with cells
US20040229878A1 (en) * 2003-05-13 2004-11-18 Depuy Spine, Inc. Transdiscal administration of specific inhibitors of P38 kinase
US7344716B2 (en) * 2003-05-13 2008-03-18 Depuy Spine, Inc. Transdiscal administration of specific inhibitors of pro-inflammatory cytokines
US7553827B2 (en) * 2003-08-13 2009-06-30 Depuy Spine, Inc. Transdiscal administration of cycline compounds
US8361467B2 (en) * 2003-07-30 2013-01-29 Depuy Spine, Inc. Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints
US8895540B2 (en) 2003-11-26 2014-11-25 DePuy Synthes Products, LLC Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
US20060127320A1 (en) * 2004-05-10 2006-06-15 Nastech Pharmaceutical Company Inc. Method of delivering parathyroid hormone to a human
US20060052305A1 (en) * 2004-05-10 2006-03-09 Nastech Pharmaceutical Company Inc. Method of treating osteoporosis using intranasal parathyroid hormone
CN101151048A (zh) * 2004-05-10 2008-03-26 纳斯泰克制药公司 增强甲状旁腺激素粘膜递送的组合物和方法
JP5007427B2 (ja) 2004-05-13 2012-08-22 アルザ コーポレイション 副甲状腺ホルモン剤の経皮送達のための装置および方法
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
WO2006073711A2 (en) 2005-01-06 2006-07-13 Kuros Biosurgery Ag Use of a matrix comprising a contrast agent in soft tissues
US7691105B2 (en) 2005-09-26 2010-04-06 Depuy Spine, Inc. Tissue augmentation, stabilization and regeneration technique
US20070088436A1 (en) * 2005-09-29 2007-04-19 Matthew Parsons Methods and devices for stenting or tamping a fractured vertebral body
US20070173447A1 (en) * 2005-10-25 2007-07-26 Nastech Pharmaceutical Company Inc. Method for treating osteoporosis by intranasal delivery of teriparatide with an anti-resorptive agent
CA2628945A1 (en) * 2005-11-10 2007-05-24 Board Of Control Of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US20080051332A1 (en) * 2005-11-18 2008-02-28 Nastech Pharmaceutical Company Inc. Method of modulating hematopoietic stem cells and treating hematologic diseases using intranasal parathyroid hormone
US20070168041A1 (en) * 2006-01-17 2007-07-19 Sudhakar Kadiyala Method and instruments for intervertebral disc augmentation through a pedicular approach
ES2381639T3 (es) 2007-04-13 2012-05-30 Kuros Biosurgery Ag Sellante polimérico para tejidos
MX2010001612A (es) * 2007-08-09 2010-07-01 Usv Ltd Novedoso procedimiento ortogonal para la purificacion de la hormona paratiroidea humana recombinante (rhpth) (1-34).
TW200930343A (en) * 2007-09-21 2009-07-16 Organon Nv Drug delivery system
US8241363B2 (en) 2007-12-19 2012-08-14 Depuy Spine, Inc. Expandable corpectomy spinal fusion cage
US8241294B2 (en) 2007-12-19 2012-08-14 Depuy Spine, Inc. Instruments for expandable corpectomy spinal fusion cage
US8986696B2 (en) * 2007-12-21 2015-03-24 Depuy Mitek, Inc. Trans-capsular administration of p38 map kinase inhibitors into orthopedic joints
US20090162351A1 (en) * 2007-12-21 2009-06-25 Depuy Spine, Inc. Transdiscal administration of inhibitors of p38 MAP kinase
EP2227263A2 (de) 2007-12-28 2010-09-15 Kuros Biosurgery AG In fibrinschaum integrierte pdgf-fusionsproteine
US8876905B2 (en) 2009-04-29 2014-11-04 DePuy Synthes Products, LLC Minimally invasive corpectomy cage and instrument
AU2009356227A1 (en) 2009-12-07 2012-06-21 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US8865220B2 (en) 2010-06-14 2014-10-21 Kaohsiung Medical University Method for controlled release of parathyroid hormone from encapsulated poly(lactic-glycolic)acid microspheres
ES2882852T3 (es) 2011-03-16 2021-12-02 Kuros Biosurgery Ag Formulación farmacéutica para la utilización en la fusión espinal
CN102731643A (zh) * 2012-06-26 2012-10-17 深圳翰宇药业股份有限公司 一种治疗骨质疏松多肽的制备方法
WO2015086489A1 (en) 2013-12-11 2015-06-18 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
CN104910269B (zh) * 2015-06-02 2018-08-17 成都圣诺生物科技股份有限公司 一种合成特立帕肽的方法
EP3685849A4 (de) * 2017-09-22 2021-12-22 Asahi Kasei Pharma Corporation Teriparatid enthaltende flüssige pharmazeutische zusammensetzung mit ausgezeichneter stabilität

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62106000A (ja) 1985-10-30 1987-05-16 Fujitsu Ltd 生体高分子結晶自動作製装置
DE3855331T2 (de) * 1987-10-20 1996-10-24 Michael F Holick Regulierung der zellenproliferation und differenzierung mittels peptiden
EP0607262A1 (de) * 1991-10-09 1994-07-27 Schering Corporation Vorrichtung zur kristallzuechtung und system zur auomatischen kristallisation
US5400741A (en) 1993-05-21 1995-03-28 Medical Foundation Of Buffalo, Inc. Device for growing crystals
US5496801A (en) * 1993-12-23 1996-03-05 Allelix Biopharmaceuticals Inc. Parathyroid hormone formulation
US5419278A (en) 1994-05-25 1995-05-30 Carter; Daniel C. Vapor equilibration tray for growing protein crystals
CA2178894A1 (en) 1995-06-15 1996-12-16 Tsunehiko Fukuda Parathyroid hormone derivatives and their use

Also Published As

Publication number Publication date
CA2315103A1 (en) 1999-06-24
KR20010033268A (ko) 2001-04-25
NO20003131L (no) 2000-06-16
AU748271B2 (en) 2002-05-30
WO1999031137A1 (en) 1999-06-24
EA200000672A1 (ru) 2000-12-25
DE69816409D1 (de) 2003-08-21
EP0926158A1 (de) 1999-06-30
HUP0100075A2 (hu) 2001-05-28
NO20003131D0 (no) 2000-06-16
JP2002508395A (ja) 2002-03-19
PE20000056A1 (es) 2000-02-08
EP0926158B1 (de) 2003-07-16
PL341209A1 (en) 2001-03-26
CN1281467A (zh) 2001-01-24
TR200002179T2 (tr) 2001-07-23
AU1632699A (en) 1999-07-05
US6590081B1 (en) 2003-07-08
ES2202729T3 (es) 2004-04-01
IL136824A0 (en) 2001-06-14
ZA9811407B (en) 2000-07-13
PT926158E (pt) 2003-11-28
BR9813740A (pt) 2000-10-10
ID25660A (id) 2000-10-19
DE69816409T2 (de) 2004-06-09
DK0926158T3 (da) 2003-11-10
AR038648A1 (es) 2005-01-26

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