DK0771322T3 - Rigeligt forekommende, ekstracellulære produkter og fremgangsmåder til fremstilling samt anvendelse deraf - Google Patents

Rigeligt forekommende, ekstracellulære produkter og fremgangsmåder til fremstilling samt anvendelse deraf

Info

Publication number
DK0771322T3
DK0771322T3 DK95901912T DK95901912T DK0771322T3 DK 0771322 T3 DK0771322 T3 DK 0771322T3 DK 95901912 T DK95901912 T DK 95901912T DK 95901912 T DK95901912 T DK 95901912T DK 0771322 T3 DK0771322 T3 DK 0771322T3
Authority
DK
Denmark
Prior art keywords
extracellular products
vaccines
majorly abundant
methods
stimulate
Prior art date
Application number
DK95901912T
Other languages
Danish (da)
English (en)
Inventor
Marcus A Horwitz
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/156,358 external-priority patent/US6752993B1/en
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of DK0771322T3 publication Critical patent/DK0771322T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Multi-Process Working Machines And Systems (AREA)
  • Telephone Function (AREA)
  • Stringed Musical Instruments (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DK95901912T 1993-11-23 1994-11-18 Rigeligt forekommende, ekstracellulære produkter og fremgangsmåder til fremstilling samt anvendelse deraf DK0771322T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/156,358 US6752993B1 (en) 1993-11-23 1993-11-23 Abundant extracellular product vaccines and methods for their production and use
US28966794A 1994-08-12 1994-08-12
PCT/US1994/013145 WO1995014713A2 (en) 1993-11-23 1994-11-18 Abundant extracellular products and methods for their production and use

Publications (1)

Publication Number Publication Date
DK0771322T3 true DK0771322T3 (da) 2008-11-24

Family

ID=26853097

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95901912T DK0771322T3 (da) 1993-11-23 1994-11-18 Rigeligt forekommende, ekstracellulære produkter og fremgangsmåder til fremstilling samt anvendelse deraf

Country Status (12)

Country Link
US (1) US6761894B1 (enExample)
EP (1) EP0771322B9 (enExample)
JP (2) JPH09505588A (enExample)
CN (1) CN1103781C (enExample)
AT (1) ATE407945T1 (enExample)
AU (1) AU1097795A (enExample)
BR (1) BR9408135A (enExample)
CA (1) CA2177249C (enExample)
DE (1) DE69435138D1 (enExample)
DK (1) DK0771322T3 (enExample)
ES (1) ES2313719T3 (enExample)
WO (1) WO1995014713A2 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141244B1 (en) * 1992-03-02 2006-11-28 Chiron Srl Helicobacter pylori proteins useful for vaccines and diagnostics
ES2313719T3 (es) 1993-11-23 2009-03-01 The Regents Of The University Of California Productos extracelulares abundantes y procedimiento de produccion y uso de los mismos.
US6752993B1 (en) 1993-11-23 2004-06-22 The Regents Of The University Of California Abundant extracellular product vaccines and methods for their production and use
US7300660B2 (en) 1993-11-23 2007-11-27 The Regents Of The University Of California Abundant extracellular products and methods for their production and use
DE69529219T2 (de) * 1994-07-01 2003-11-06 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Helicobacter proteine und impstoffe
WO1996005223A1 (en) * 1994-08-12 1996-02-22 The Regents Of The University Of California Abundant extracellular products and methods for their production and use
WO1996037219A1 (en) * 1995-05-23 1996-11-28 The Regents Of The University Of California Abundant extracellular products and methods for their production and use
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6592877B1 (en) 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6338852B1 (en) 1995-09-01 2002-01-15 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6290969B1 (en) 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
GB2324093A (en) * 1996-01-04 1998-10-14 Rican Limited Helicobacter pylori bacterioferritin
ATE396269T1 (de) * 1996-07-26 2008-06-15 Pasteur Institut Desaturase-antigen aus mycobakterium tubercolosis
US6284255B1 (en) * 1996-08-29 2001-09-04 Genesis Research & Development Corporation Limited Compounds and methods for treatment and diagnosis of mycobacterial infections
US6013660A (en) * 1996-10-02 2000-01-11 The Regents Of The University Of California Externally targeted prophylactic and chemotherapeutic method and agents
AU6029898A (en) * 1997-01-21 1998-08-07 Regents Of The University Of California, The Abundant extracellular products and methods for their production and use
US6627198B2 (en) 1997-03-13 2003-09-30 Corixa Corporation Fusion proteins of Mycobacterium tuberculosis antigens and their uses
US6544522B1 (en) 1998-12-30 2003-04-08 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
US6350456B1 (en) * 1997-03-13 2002-02-26 Corixa Corporation Compositions and methods for the prevention and treatment of M. tuberculosis infection
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US5968524A (en) * 1997-12-23 1999-10-19 Genesis Research & Development Corp. Methods and compounds for the treatment of immunologically-mediated psoriasis
US6465633B1 (en) 1998-12-24 2002-10-15 Corixa Corporation Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis
NZ581306A (en) 2004-11-16 2011-03-31 Crucell Holland Bv Multivalent vaccines comprising recombinant viral vectors
CN102850445B (zh) * 2012-09-24 2014-01-08 张银辉 一组结核分枝杆菌菌体特异性抗原及其纯化方法

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5856073A (en) 1973-06-28 1975-01-30 Toru Tsumits Tuberculin active proteins and peptides
US3888837A (en) 1973-06-28 1975-06-10 Mitsui Pharmaceuticals Tuberculin active proteins and peptides from the cells of tubercle bacilli
US4123427A (en) 1976-07-27 1978-10-31 Daniel Thomas M Method for the purification of mycobacterial protein antigens and resulting product
US4460503A (en) 1983-03-15 1984-07-17 Institut Pasteur Tuberculine active peptides and a process for preparing same by chemical synthesis
GB8404280D0 (en) 1984-02-17 1984-03-21 Stanford J L Biological preparations
US4777130A (en) 1984-12-05 1988-10-11 Andra Biologicals Isolation of mycobacterial a 60 antigen for diagnostic purposes
US4689397A (en) 1985-08-12 1987-08-25 Scripps Clinic And Research Foundation Synthetic polypeptides for detecting mycobacterial infections
US4906742A (en) 1986-07-31 1990-03-06 Whitehead Institute For Biomedical Research Encoding antigens of M. Leprae
AU8020387A (en) 1986-09-08 1988-04-07 Applied Biotechnology, Inc. Genetically engineered vaccines for mycobacteria
US5268170A (en) 1986-09-09 1993-12-07 Yeda Research And Development Co., Ltd. Methods of treatment and diagnosis of autoimmune diseases, especially arthritic conditions
AU1548388A (en) 1987-02-02 1988-08-24 Whitehead Institute For Biomedical Research Mycobacterium tuberculosis genes and encoding protein antigens
US4976958A (en) 1987-02-26 1990-12-11 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US4952395A (en) 1987-02-26 1990-08-28 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US5504005A (en) 1987-03-02 1996-04-02 Albert Einstein College Of Medicine Of Yeshiva University Recombinant mycobacterial vaccine
EP0347425B1 (en) 1987-03-02 1995-12-27 Whitehead Institute For Biomedical Research Recombinant mycobacterial vaccine
US5225324A (en) 1987-04-24 1993-07-06 Bioscience International, Inc. Diagnostics for mycobacteria in public health, medical, and veterinary practice
WO1989005825A1 (en) 1987-12-22 1989-06-29 Immunex Corporation EXPRESSION OF RECOMBINANT 18/16.6 AND 15.2 kD PROTEIN ANTIGENS OF MYCOBACTERIUM LEPRAE
NL8703107A (nl) 1987-12-22 1989-07-17 Nederlanden Staat Polypeptiden en derivaten daarvan, alsmede de toepassing daarvan in farmaceutische en diagnostische preparaten.
EP0419569B1 (en) 1988-06-15 1995-09-06 Whitehead Institute For Biomedical Research Stress proteins and uses therefor
US5108745B1 (en) 1988-08-16 1998-06-30 Univ California Tuberculosis and legionellosis vaccines and methods for their production
WO1990002564A1 (en) 1988-09-12 1990-03-22 Codon Vaccine diagnostic employing proteins homologous to heat shock proteins of trypanosoma cruzi
US5114844A (en) * 1989-03-14 1992-05-19 Yeda Research And Development Co., Ltd. Diagnosis and treatment of insulin dependent diabetes mellitus
CA2063414A1 (en) 1989-06-19 1990-12-20 Richard A. Young Vector-mediated genomic insertion and expression of dna in bcg
EP0419355B1 (en) * 1989-09-19 2000-02-09 N.V. Innogenetics S.A. Recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnostic of tuberculosis
WO1991004272A1 (en) * 1989-09-19 1991-04-04 N.V. Innogenetics S.A. Recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnostic of tuberculosis
SE9001105D0 (sv) 1990-03-27 1990-03-27 Astra Ab New methods foer diagnosis of tuberculosis
GB2239246A (en) 1989-12-22 1991-06-26 Astra Ab Protein antigen from Mycobacterium tuberculosis
CA2045842A1 (en) 1990-07-16 1992-01-17 William R. Jacobs Dna capable of site-specific integration into mycobacteria
GB9015888D0 (en) 1990-07-19 1990-09-05 Smithkline Biolog Vectors
US5254459A (en) 1990-08-23 1993-10-19 Patarroyo Manuel E Nucleotide and amino acid sequences of protein MTP40 of M. tuberculosis and synthetic peptides derived therefrom
US5169940A (en) 1990-08-23 1992-12-08 Patarroyo Manuel E Nucleotide sequences of protein MTP40 of M. tuberculosis
US5171839A (en) 1990-08-23 1992-12-15 Patarroyo Manuel E Nucleotide and amino acid sequences of protein mtp40 of m. tuberculosis and synthetic peptides derived therefrom
EP0547166A1 (en) 1990-09-06 1993-06-23 Immulogic Pharmaceutical Corporation Pathogen-specific ctl therapy
EP0499003A1 (en) * 1991-02-14 1992-08-19 N.V. Innogenetics S.A. Polypeptides and peptides, particularly recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnosis of tuberculosis
WO1992016628A1 (en) 1991-03-25 1992-10-01 N.V. Innogenetics S.A. Polypeptides from mycobacterium paratuberculosis
GB9111291D0 (en) 1991-05-24 1991-07-17 Medical Res Council Diagnostic peptides
EP0587775A4 (en) 1991-06-06 1994-11-02 Medimmune Inc INDUCTION OF THE CTL RESPONSE BY FOREIGN ANTIGENS EXPRESSED IN MYCOBACTERIES.
FR2677365B1 (fr) 1991-06-07 1995-08-04 Pasteur Institut Proteines de mycobacterium et applications.
FI935566A0 (fi) 1991-06-13 1993-12-10 Einstein Coll Med Insertionsmutationer i mycobakterier
WO1993007897A1 (en) 1991-10-21 1993-04-29 Medimmune, Inc. Bacterial expression vectors containing dna encoding secretion signals of lipoproteins
FR2682967B1 (fr) 1991-10-25 1994-01-14 Pasteur Institut Nouveau promoteur de m. paratuberculosis. son utilisation pour le clonage et l'expression de sequences nucleotidiques.
GB9200949D0 (en) 1992-01-17 1992-03-11 Medical Res Council Diagnostic peptides
WO1993014789A1 (en) 1992-01-22 1993-08-05 New England Medical Center Hospitals, Inc. Pathogen-specific ctl therapy
FR2687410A1 (fr) 1992-02-14 1993-08-20 Pasteur Institut Beta-lactamase recombinante, utilisable en tant que molecule porteuse pour la preparation de compositions immunogenes.
FR2688785B1 (fr) 1992-03-19 1995-07-07 Pasteur Institut Sequence peptidique apte a induire une reaction d'hypersensibilite de type retarde en presence de bacteries vivantes du complexe mycobacterium tuberculosis, et ses applications.
AU4580093A (en) 1992-07-22 1994-02-14 Proteus Molecular Design Limited Polypeptide antigens of mycobacterium bovis
DK79893D0 (da) 1993-07-02 1993-07-02 Statens Seruminstitut New vaccine
DK79793D0 (da) 1993-07-02 1993-07-02 Statens Seruminstitut Diagnostic test
ES2313719T3 (es) 1993-11-23 2009-03-01 The Regents Of The University Of California Productos extracelulares abundantes y procedimiento de produccion y uso de los mismos.

Also Published As

Publication number Publication date
EP0771322B9 (en) 2009-08-12
WO1995014713A3 (en) 1995-12-28
DE69435138D1 (de) 2008-10-23
JP4537178B2 (ja) 2010-09-01
EP0771322A1 (en) 1997-05-07
WO1995014713A2 (en) 1995-06-01
ES2313719T3 (es) 2009-03-01
CN1103781C (zh) 2003-03-26
ATE407945T1 (de) 2008-09-15
AU1097795A (en) 1995-06-13
CN1142231A (zh) 1997-02-05
JPH09505588A (ja) 1997-06-03
CA2177249A1 (en) 1995-06-01
US6761894B1 (en) 2004-07-13
JP2005104983A (ja) 2005-04-21
EP0771322B1 (en) 2008-09-10
CA2177249C (en) 2010-10-19
BR9408135A (pt) 1997-08-05

Similar Documents

Publication Publication Date Title
BR9408135A (pt) Produtos extra-celulares abundantes e processos para sua produção e uso
CA2050749A1 (en) Nucleotide sequence coding for an outer membrane protein from neisseria meningitidis and use of said protein in vaccine preparations
NO20070618L (no) Forbindelser og fremgangsmater for immunterapi og diagnose av tuberkulose.
ATE26127T1 (de) Rekombinante dna, damit transformierte wirtsorganismen und durch die wirtsorganismen hergestellte polypeptide; verfahren zu ihrer herstellung; nachweisverfahren unter benutzung der polypeptide; die polypeptide enthaltende zusammensetzungen und mittel; dna-sequenzen.
NO331103B1 (no) Polypeptid for induksjon av immunrespons mot Streptococcus Pneumoniae, polynukleotid og ekspresjonsvektor inneholdende dette samt vertscelle og fremgangsmate for produksjon av polypeptidet og vaksinesammensetning omfattende dette
MXPA02006888A (es) Flavivirus recombinantes y metodos para utilizar los mismos.
BR9608894A (pt) Produtos extracelulares abundantes e processos para suas producões e usos
ATE263836T1 (de) Chimere proteine, welche borrelia polypeptide beinhalten, verwendungen dafür
AU6029898A (en) Abundant extracellular products and methods for their production and use
DK0914437T3 (da) Identificering og kloning af et mykobakterieantigen svarende til et heparinbindende hæmagglutinin
GB9409985D0 (en) Vaccine against mycobacterial infections
WO2004035006A3 (en) Methods and compositions for immunization against hiv
DE69836520D1 (de) Clostridium perfringens Impfstoff
WO2004103269A3 (en) Methods and compositions for vaccination comprising nucleic acid and/or polypeptide sequences of the genus borrelia
CY1107784T1 (el) Πρωτεϊνη συντηξης g του ihnv για διεγερση του ανοσοποιητικου συστηματος
DE60042268D1 (de) Deletierte sequenzen in m. bovis bcg / m. bovis oder m. tuberculosis, verfahren zur erkennung von mycobakterien mit diesen sequenzen und vakzine
MX9701103A (es) Productos extracelulares abundantes y metodos para su produccion y uso.
WO2000039301A3 (en) Methods for using mycobacterium tuberculosis molecules as immunological adjuvants
KR900701831A (ko) 열대열 말라리아 원충의 분열소체 표면 항원의 대립형질 변이주
WO2005060328A3 (en) ENCODING NUCLEOTIDES OF GENES FROM THE CHROMOSOME OF THE BACTERIUM Mycoplasma hyopneumoniae, EXPRESSION AND ACTIVITY OF THE POLYNUCLEOTIDES AND THEIR APPLICATIONS
ATE305941T1 (de) Impfstoff
MY106940A (en) Allelic variants of plasmodium falciparum merozoite surface antigen.
TH34251A (th) วิธีการสำหรับการทำให้เกิดการแสดงออกของจีนของเด็งกีไวรัส
NZ510063A (en) Abundant extracellular products and methods for their production and use
WO2006078271A3 (en) Cloning and expression of the full length 110 kda antigen of orientia tsutsugamushi to be used as a vaccine component against scrub typhus