WO2005060328A3 - ENCODING NUCLEOTIDES OF GENES FROM THE CHROMOSOME OF THE BACTERIUM Mycoplasma hyopneumoniae, EXPRESSION AND ACTIVITY OF THE POLYNUCLEOTIDES AND THEIR APPLICATIONS - Google Patents

ENCODING NUCLEOTIDES OF GENES FROM THE CHROMOSOME OF THE BACTERIUM Mycoplasma hyopneumoniae, EXPRESSION AND ACTIVITY OF THE POLYNUCLEOTIDES AND THEIR APPLICATIONS Download PDF

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Publication number
WO2005060328A3
WO2005060328A3 PCT/BR2004/000257 BR2004000257W WO2005060328A3 WO 2005060328 A3 WO2005060328 A3 WO 2005060328A3 BR 2004000257 W BR2004000257 W BR 2004000257W WO 2005060328 A3 WO2005060328 A3 WO 2005060328A3
Authority
WO
WIPO (PCT)
Prior art keywords
polynucleotides
sequences
mycoplasma hyopneumoniae
amino acid
chromosome
Prior art date
Application number
PCT/BR2004/000257
Other languages
French (fr)
Other versions
WO2005060328A2 (en
Inventor
Vasconcelos Ana Tereza Ribe De
Anamaria Aranha Camargo
Dirce Maria Carraro
Sandro Luis Bonatto
Humberto Maciel Franca Madeira
Samuel Goldenberg
Edmundo Carlos Grisard
Odir Antonio Dellagostin
Da Cunha Cristina Wetzel
Itamar Antonio Piffer
Vainstein Marilene Henning
Arnaldo Zaha
Schrank Irene Silveira
Ferreira Henrique Bunselmeyer
Augusto Schrank
Martinkovics Chrystyann Thomaz
Original Assignee
Conselho Nacional Cnpq
Vasconcelos Ana Tereza Ribe De
Anamaria Aranha Camargo
Dirce Maria Carraro
Sandro Luis Bonatto
Humberto Maciel Franca Madeira
Samuel Goldenberg
Edmundo Carlos Grisard
Odir Antonio Dellagostin
Da Cunha Cristina Wetzel
Itamar Antonio Piffer
Vainstein Marilene Henning
Arnaldo Zaha
Schrank Irene Silveira
Ferreira Henrique Bunselmeyer
Augusto Schrank
Martinkovics Chrystyann Thomaz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conselho Nacional Cnpq, Vasconcelos Ana Tereza Ribe De, Anamaria Aranha Camargo, Dirce Maria Carraro, Sandro Luis Bonatto, Humberto Maciel Franca Madeira, Samuel Goldenberg, Edmundo Carlos Grisard, Odir Antonio Dellagostin, Da Cunha Cristina Wetzel, Itamar Antonio Piffer, Vainstein Marilene Henning, Arnaldo Zaha, Schrank Irene Silveira, Ferreira Henrique Bunselmeyer, Augusto Schrank, Martinkovics Chrystyann Thomaz filed Critical Conselho Nacional Cnpq
Publication of WO2005060328A2 publication Critical patent/WO2005060328A2/en
Publication of WO2005060328A3 publication Critical patent/WO2005060328A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/30—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present invention refers to the gene sequences and to the polypeptides encoded by these gene sequences, and to the use of these sequences capable of inducing a protective immune response in animals. The invention is related to the identification of gene sequences of Mycoplasma hyopneumoniae with antigenic potential to be used as vaccines1 or in diagnosis. The invention refers to the polynucleotide sequences of a group consisting of: a) identical polynucleotides, with identity of at least 70%, to the nucleotide sequences that code for polypeptides characterized by the amino acid sequences, and fragments of them; b) identical polynucleotides, with identity of at least 70%, to polynucleotides that code for the polypeptides corresponding to the listed sequences, and that can be preferentially isolated from the chromosome of the strain 7448 of Mycoplasma hyopneumoniae, registered in the bacterial collection of the Centro Nacional de Pesquisa em Suinos e Ave, EMBRAPA, under the number 7448; c) polynucleotides encoding polypeptides characterized by identical amino acid sequences, in at least 70%, to the amino acid sequences; d) polynucleotides that are complementary to the polynucleotides of a, b, or c; e) polynucleotides including successive nucleotide bases from the polynucleotide sequences of a, b, or c; f) a cultivation process, preferentially of Mycoplasma hyopneumoniae, in which the genes encoded by the listed polynucleotide sequences are amplified; g) methods for the serological diagnosis of the M. hyopneumoniae infection in mammals; h) immunogenic compositions containing proteins.
PCT/BR2004/000257 2003-12-23 2004-12-21 ENCODING NUCLEOTIDES OF GENES FROM THE CHROMOSOME OF THE BACTERIUM Mycoplasma hyopneumoniae, EXPRESSION AND ACTIVITY OF THE POLYNUCLEOTIDES AND THEIR APPLICATIONS WO2005060328A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BR0306775A BR0306775A (en) 2003-12-23 2003-12-23 Polynucleotides encoding chromosome activities of the bacterium mycoplasma hyopneumoniae
BRPI0306775-0 2003-12-23

Publications (2)

Publication Number Publication Date
WO2005060328A2 WO2005060328A2 (en) 2005-07-07
WO2005060328A3 true WO2005060328A3 (en) 2006-04-13

Family

ID=34705776

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2004/000257 WO2005060328A2 (en) 2003-12-23 2004-12-21 ENCODING NUCLEOTIDES OF GENES FROM THE CHROMOSOME OF THE BACTERIUM Mycoplasma hyopneumoniae, EXPRESSION AND ACTIVITY OF THE POLYNUCLEOTIDES AND THEIR APPLICATIONS

Country Status (2)

Country Link
BR (1) BR0306775A (en)
WO (1) WO2005060328A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101764750B1 (en) * 2013-02-05 2017-08-03 애그리컬쳐럴 테크놀로지 리서치 인스티튜트 Anti-Mycoplasma Spp. Subunit Vaccine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHAMBAUD I. ET AL: "The complete genome sequence of the murine respiratory pathogen Mycoplasma pulmonis.", NUCLEIC ACIDS RESEARCH, vol. 29, no. 10, 2001, pages 2145 - 2153, XP002998501 *
PAPAZISI L. ET AL: "The complete genome sequence of the avian pathogen Mycoplasma gallisepticum strain R(low).", MICROBIOLOGY, vol. 149, 2003, pages 2307 - 2316, XP002998502 *

Also Published As

Publication number Publication date
WO2005060328A2 (en) 2005-07-07
BR0306775A (en) 2005-10-04

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