BR9408135A - Produtos extra-celulares abundantes e processos para sua produção e uso - Google Patents

Produtos extra-celulares abundantes e processos para sua produção e uso

Info

Publication number
BR9408135A
BR9408135A BR9408135A BR9408135A BR9408135A BR 9408135 A BR9408135 A BR 9408135A BR 9408135 A BR9408135 A BR 9408135A BR 9408135 A BR9408135 A BR 9408135A BR 9408135 A BR9408135 A BR 9408135A
Authority
BR
Brazil
Prior art keywords
vaccines
extracellular products
production
majorly abundant
stimulate
Prior art date
Application number
BR9408135A
Other languages
English (en)
Portuguese (pt)
Inventor
Marcus A Horwitz
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/156,358 external-priority patent/US6752993B1/en
Application filed by Univ California filed Critical Univ California
Publication of BR9408135A publication Critical patent/BR9408135A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Telephone Function (AREA)
  • Stringed Musical Instruments (AREA)
  • Multi-Process Working Machines And Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
BR9408135A 1993-11-23 1994-11-18 Produtos extra-celulares abundantes e processos para sua produção e uso BR9408135A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/156,358 US6752993B1 (en) 1993-11-23 1993-11-23 Abundant extracellular product vaccines and methods for their production and use
US28966794A 1994-08-12 1994-08-12
PCT/US1994/013145 WO1995014713A2 (en) 1993-11-23 1994-11-18 Abundant extracellular products and methods for their production and use

Publications (1)

Publication Number Publication Date
BR9408135A true BR9408135A (pt) 1997-08-05

Family

ID=26853097

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9408135A BR9408135A (pt) 1993-11-23 1994-11-18 Produtos extra-celulares abundantes e processos para sua produção e uso

Country Status (12)

Country Link
US (1) US6761894B1 (enExample)
EP (1) EP0771322B9 (enExample)
JP (2) JPH09505588A (enExample)
CN (1) CN1103781C (enExample)
AT (1) ATE407945T1 (enExample)
AU (1) AU1097795A (enExample)
BR (1) BR9408135A (enExample)
CA (1) CA2177249C (enExample)
DE (1) DE69435138D1 (enExample)
DK (1) DK0771322T3 (enExample)
ES (1) ES2313719T3 (enExample)
WO (1) WO1995014713A2 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141244B1 (en) * 1992-03-02 2006-11-28 Chiron Srl Helicobacter pylori proteins useful for vaccines and diagnostics
US6752993B1 (en) 1993-11-23 2004-06-22 The Regents Of The University Of California Abundant extracellular product vaccines and methods for their production and use
JPH09505588A (ja) 1993-11-23 1997-06-03 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 多くの細胞外生成物及びそれらの製造法並びに使用
US7300660B2 (en) 1993-11-23 2007-11-27 The Regents Of The University Of California Abundant extracellular products and methods for their production and use
JPH10502365A (ja) * 1994-07-01 1998-03-03 リカン・リミテッド ヘリコバクタータンパク質およびワクチン
WO1996005223A1 (en) * 1994-08-12 1996-02-22 The Regents Of The University Of California Abundant extracellular products and methods for their production and use
NZ309945A (en) * 1995-05-23 2001-04-27 Univ California Abundant extracellular products and their use as vaccines
US6592877B1 (en) 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6290969B1 (en) 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6338852B1 (en) 1995-09-01 2002-01-15 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
EP0909323B1 (en) * 1996-01-04 2007-02-28 Novartis Vaccines and Diagnostics, Inc. Helicobacter pylori bacterioferritin
DE69738718D1 (de) * 1996-07-26 2008-07-03 Pasteur Institut Desaturase-antigen aus mycobakterium tubercolosis
US6284255B1 (en) * 1996-08-29 2001-09-04 Genesis Research & Development Corporation Limited Compounds and methods for treatment and diagnosis of mycobacterial infections
US6013660A (en) * 1996-10-02 2000-01-11 The Regents Of The University Of California Externally targeted prophylactic and chemotherapeutic method and agents
JP2001512435A (ja) * 1997-01-21 2001-08-21 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 豊富な細胞外産物ならびにそれらの産生および使用方法
US6544522B1 (en) 1998-12-30 2003-04-08 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
US6350456B1 (en) * 1997-03-13 2002-02-26 Corixa Corporation Compositions and methods for the prevention and treatment of M. tuberculosis infection
US6627198B2 (en) 1997-03-13 2003-09-30 Corixa Corporation Fusion proteins of Mycobacterium tuberculosis antigens and their uses
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US5968524A (en) * 1997-12-23 1999-10-19 Genesis Research & Development Corp. Methods and compounds for the treatment of immunologically-mediated psoriasis
US6465633B1 (en) 1998-12-24 2002-10-15 Corixa Corporation Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis
BRPI0518933A2 (pt) 2004-11-16 2008-12-16 Crucell Holland B V E Aeras Gl adenovÍrus recombinante defeituoso de replicaÇço, vetor de polinucleotÍdeo recombinante, vacina multivalente da tuberculose, e, uso do antÍgeno tb10.4 de mycobacterium
CN102850445B (zh) * 2012-09-24 2014-01-08 张银辉 一组结核分枝杆菌菌体特异性抗原及其纯化方法

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5856073A (en) 1973-06-28 1975-01-30 Toru Tsumits Tuberculin active proteins and peptides
US3888837A (en) 1973-06-28 1975-06-10 Mitsui Pharmaceuticals Tuberculin active proteins and peptides from the cells of tubercle bacilli
US4123427A (en) 1976-07-27 1978-10-31 Daniel Thomas M Method for the purification of mycobacterial protein antigens and resulting product
US4460503A (en) 1983-03-15 1984-07-17 Institut Pasteur Tuberculine active peptides and a process for preparing same by chemical synthesis
GB8404280D0 (en) 1984-02-17 1984-03-21 Stanford J L Biological preparations
US4777130A (en) 1984-12-05 1988-10-11 Andra Biologicals Isolation of mycobacterial a 60 antigen for diagnostic purposes
US4689397A (en) 1985-08-12 1987-08-25 Scripps Clinic And Research Foundation Synthetic polypeptides for detecting mycobacterial infections
US4906742A (en) 1986-07-31 1990-03-06 Whitehead Institute For Biomedical Research Encoding antigens of M. Leprae
WO1988002027A1 (en) 1986-09-08 1988-03-24 Applied Biotechnology, Inc. Genetically engineered vaccines for mycobacteria
US5268170A (en) 1986-09-09 1993-12-07 Yeda Research And Development Co., Ltd. Methods of treatment and diagnosis of autoimmune diseases, especially arthritic conditions
EP0345299A1 (en) 1987-02-02 1989-12-13 Whitehead Institute For Biomedical Research Mycobacterium tuberculosis genes encoding protein antigens
US4952395A (en) 1987-02-26 1990-08-28 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US4976958A (en) 1987-02-26 1990-12-11 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
WO1988006626A1 (en) 1987-03-02 1988-09-07 Whitehead Institute For Biomedical Research Recombinant mycobacterial vaccine
US5504005A (en) 1987-03-02 1996-04-02 Albert Einstein College Of Medicine Of Yeshiva University Recombinant mycobacterial vaccine
US5225324A (en) 1987-04-24 1993-07-06 Bioscience International, Inc. Diagnostics for mycobacteria in public health, medical, and veterinary practice
NL8703107A (nl) 1987-12-22 1989-07-17 Nederlanden Staat Polypeptiden en derivaten daarvan, alsmede de toepassing daarvan in farmaceutische en diagnostische preparaten.
WO1989005825A1 (en) 1987-12-22 1989-06-29 Immunex Corporation EXPRESSION OF RECOMBINANT 18/16.6 AND 15.2 kD PROTEIN ANTIGENS OF MYCOBACTERIUM LEPRAE
ATE127345T1 (de) 1988-06-15 1995-09-15 Whitehead Biomedical Inst Stressproteine und verwendungen dafür.
US5108745B1 (en) 1988-08-16 1998-06-30 Univ California Tuberculosis and legionellosis vaccines and methods for their production
WO1990002564A1 (en) 1988-09-12 1990-03-22 Codon Vaccine diagnostic employing proteins homologous to heat shock proteins of trypanosoma cruzi
US5114844A (en) * 1989-03-14 1992-05-19 Yeda Research And Development Co., Ltd. Diagnosis and treatment of insulin dependent diabetes mellitus
CA2063414A1 (en) 1989-06-19 1990-12-20 Richard A. Young Vector-mediated genomic insertion and expression of dna in bcg
EP0419355B1 (en) * 1989-09-19 2000-02-09 N.V. Innogenetics S.A. Recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnostic of tuberculosis
CA2042016C (en) * 1989-09-19 2004-04-06 Jean Content Recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnostic of tuberculosis
SE9001105D0 (sv) 1990-03-27 1990-03-27 Astra Ab New methods foer diagnosis of tuberculosis
AU6807390A (en) 1989-12-22 1991-06-27 Astra Aktiebolag New methods of diagnosis of tuberculosis
CA2045842A1 (en) 1990-07-16 1992-01-17 William R. Jacobs Dna capable of site-specific integration into mycobacteria
GB9015888D0 (en) 1990-07-19 1990-09-05 Smithkline Biolog Vectors
US5169940A (en) 1990-08-23 1992-12-08 Patarroyo Manuel E Nucleotide sequences of protein MTP40 of M. tuberculosis
US5254459A (en) 1990-08-23 1993-10-19 Patarroyo Manuel E Nucleotide and amino acid sequences of protein MTP40 of M. tuberculosis and synthetic peptides derived therefrom
US5171839A (en) 1990-08-23 1992-12-15 Patarroyo Manuel E Nucleotide and amino acid sequences of protein mtp40 of m. tuberculosis and synthetic peptides derived therefrom
CA2089488A1 (en) 1990-09-06 1993-03-07 Judy Lieberman Pathogen-specific ctl therapy
EP0499003A1 (en) * 1991-02-14 1992-08-19 N.V. Innogenetics S.A. Polypeptides and peptides, particularly recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnosis of tuberculosis
DE69231519T2 (de) 1991-03-25 2001-05-31 N.V. Innogenetics S.A., Gent Polypeptide aus micobakterium paratuberculosis
GB9111291D0 (en) 1991-05-24 1991-07-17 Medical Res Council Diagnostic peptides
WO1992021376A1 (en) 1991-06-06 1992-12-10 Med Immune, Inc. Induction of ctl responses to foreign antigens expressed in mycobacteria
FR2677365B1 (fr) 1991-06-07 1995-08-04 Pasteur Institut Proteines de mycobacterium et applications.
JPH06511145A (ja) 1991-06-13 1994-12-15 アルバート アインシュタイン カレッジ オブ メディシン、ア ディビジョン オブ イェシーバ ユニバーシティ ミコバクテリア内での挿入突然変異
AU681572B2 (en) 1991-10-21 1997-09-04 Med Immune, Inc. Bacterial expression vectors containing DNA encoding secretion signals of lipoproteins
FR2682967B1 (fr) 1991-10-25 1994-01-14 Pasteur Institut Nouveau promoteur de m. paratuberculosis. son utilisation pour le clonage et l'expression de sequences nucleotidiques.
GB9200949D0 (en) 1992-01-17 1992-03-11 Medical Res Council Diagnostic peptides
AU3483293A (en) 1992-01-22 1993-09-01 New England Medical Center Hospitals, Inc., The Pathogen-specific CTL therapy
FR2687410A1 (fr) 1992-02-14 1993-08-20 Pasteur Institut Beta-lactamase recombinante, utilisable en tant que molecule porteuse pour la preparation de compositions immunogenes.
FR2688785B1 (fr) 1992-03-19 1995-07-07 Pasteur Institut Sequence peptidique apte a induire une reaction d'hypersensibilite de type retarde en presence de bacteries vivantes du complexe mycobacterium tuberculosis, et ses applications.
IL106436A0 (en) 1992-07-22 1993-11-15 Proteus Molecular Design Synthetic polypeptides and their use
DK79893D0 (da) 1993-07-02 1993-07-02 Statens Seruminstitut New vaccine
DK79793D0 (da) 1993-07-02 1993-07-02 Statens Seruminstitut Diagnostic test
JPH09505588A (ja) 1993-11-23 1997-06-03 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 多くの細胞外生成物及びそれらの製造法並びに使用

Also Published As

Publication number Publication date
JP2005104983A (ja) 2005-04-21
EP0771322B1 (en) 2008-09-10
EP0771322A1 (en) 1997-05-07
JPH09505588A (ja) 1997-06-03
CA2177249A1 (en) 1995-06-01
ES2313719T3 (es) 2009-03-01
JP4537178B2 (ja) 2010-09-01
DE69435138D1 (de) 2008-10-23
EP0771322B9 (en) 2009-08-12
WO1995014713A2 (en) 1995-06-01
CN1142231A (zh) 1997-02-05
AU1097795A (en) 1995-06-13
DK0771322T3 (da) 2008-11-24
US6761894B1 (en) 2004-07-13
CA2177249C (en) 2010-10-19
CN1103781C (zh) 2003-03-26
ATE407945T1 (de) 2008-09-15
WO1995014713A3 (en) 1995-12-28

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
B09B Patent application refused [chapter 9.2 patent gazette]