ATE473238T1 - Tuberkulose vaccine mit verbesserter effizienz - Google Patents

Tuberkulose vaccine mit verbesserter effizienz

Info

Publication number
ATE473238T1
ATE473238T1 AT04729090T AT04729090T ATE473238T1 AT E473238 T1 ATE473238 T1 AT E473238T1 AT 04729090 T AT04729090 T AT 04729090T AT 04729090 T AT04729090 T AT 04729090T AT E473238 T1 ATE473238 T1 AT E473238T1
Authority
AT
Austria
Prior art keywords
nucleic acid
acid molecules
improved efficiency
tuberculosis vaccine
present
Prior art date
Application number
AT04729090T
Other languages
English (en)
Inventor
Leander Grode
Stefan Kaufmann
Baerbel Raupach
Juergen Hess
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Application granted granted Critical
Publication of ATE473238T1 publication Critical patent/ATE473238T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT04729090T 2003-04-23 2004-04-23 Tuberkulose vaccine mit verbesserter effizienz ATE473238T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46464403P 2003-04-23 2003-04-23
PCT/EP2004/004345 WO2004094469A1 (en) 2003-04-23 2004-04-23 Tuberculosis vaccine with improved efficacy

Publications (1)

Publication Number Publication Date
ATE473238T1 true ATE473238T1 (de) 2010-07-15

Family

ID=33310924

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04729090T ATE473238T1 (de) 2003-04-23 2004-04-23 Tuberkulose vaccine mit verbesserter effizienz

Country Status (24)

Country Link
US (2) US7988980B2 (de)
EP (1) EP1618128B1 (de)
JP (1) JP4662925B2 (de)
KR (1) KR101101263B1 (de)
CN (1) CN1798762B (de)
AT (1) ATE473238T1 (de)
AU (1) AU2004232485B2 (de)
BR (1) BRPI0409789B8 (de)
CA (1) CA2523084C (de)
CU (1) CU23608A3 (de)
CY (1) CY1110793T1 (de)
DE (1) DE602004028000D1 (de)
DK (1) DK1618128T3 (de)
ES (1) ES2344698T3 (de)
HK (1) HK1091217A1 (de)
HR (1) HRP20100395T1 (de)
MX (1) MXPA05011360A (de)
PL (1) PL1618128T3 (de)
PT (1) PT1618128E (de)
RU (1) RU2342400C2 (de)
SI (1) SI1618128T1 (de)
UA (1) UA91180C2 (de)
WO (1) WO2004094469A1 (de)
ZA (1) ZA200508276B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1798762B (zh) * 2003-04-23 2010-04-28 马普科技促进协会 效能提高的结核病疫苗
EP1649869A1 (de) * 2004-10-21 2006-04-26 Vakzine Projekt Management GmbH Kombination von rekombinanten Mycobakterien und einem biologisch aktiven Agent als Vakzine
DK1827504T3 (da) 2004-12-01 2011-08-29 Aeras Global Tb Vaccine Foundation Rekombinante BCG-stammer med forøget evne til at undslippe fra endosomet
WO2009089535A2 (en) * 2008-01-11 2009-07-16 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Polypeptide vaccine and vaccination strategy against mycobacterium
WO2011031139A1 (en) 2009-09-09 2011-03-17 Universiteit Utrecht Holding B.V. An ataq protein or a part thereof as a vaccine
SA110310855B1 (ar) 2009-11-13 2014-09-16 Laboratories Leti S L Unipersonal استخدام مصدر l3 و/ أو l5 كلقاح أو كوسيلة تشخيصية لمرض طفيلي
RU2586774C2 (ru) 2010-08-27 2016-06-10 Пантархей Байосайенс Б.В. Иммунотерапевтический способ лечения рака простаты
ES2685928T3 (es) 2010-09-20 2018-10-15 Vakzine Projekt Management Gmbh Mycobacterium recombinante como vacuna para uso en seres humanos
CA2817421C (en) 2010-11-10 2020-04-14 Laboratorios Leti, S.L. Adjuvant derived from leishmania species
SI2654783T1 (sl) * 2010-12-21 2017-02-28 Max-Planck-Gesellschaft zur Fourderung der Wissenschaften e.V. Rekombinantni mycobacterium kot cepivo
SG191331A1 (en) 2010-12-21 2013-07-31 Max Planck Gesellschaft Determination of the efficacy of an anti-mycobacterial vaccination
RU2520078C1 (ru) * 2013-04-25 2014-06-20 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации (ФГБУ "НИИЭМ им. Н.Ф. Гамалеи" Минздрава России) СПОСОБ ПОЛУЧЕНИЯ ИММУНОГЕННОЙ КОМПОЗИЦИИ НА ОСНОВЕ ГИБРИДНОГО БЕЛКА Ag85A-DBD И ДЕКСТРАНА, РЕКОМБИНАНТНАЯ ПЛАЗМИДА pAg85A-DBD, ШТАММ Escherichia coli [pREP4, pAg85A-DBD], ХИМЕРНЫЙ БЕЛОК Ag85A-DBD
WO2016080830A2 (en) 2014-11-18 2016-05-26 Pantarhei Bioscience B.V. Immunotherapeutic method for treating pancreatic cancer
EP3090757A1 (de) * 2015-05-04 2016-11-09 Vakzine Projekt Management GmbH Rekombinantes mycobakterium als immuntherapeutikum zur behandlung von krebs
US20180256633A1 (en) 2015-09-18 2018-09-13 Rijksuniversiteit Groningen Long chain inulin for stimulating an immune response
KR101825439B1 (ko) * 2016-04-15 2018-02-05 배재대학교 산학협력단 염산 처리에 의한 그람양성 박테리아 고스트의 제조 방법
WO2018184188A1 (en) * 2017-04-07 2018-10-11 Chengdu Yongan Pharmaceutical Co., Ltd. RECOMBINANT BCG OVEREXPRESSING phoP-phoR
US10387139B2 (en) * 2017-07-25 2019-08-20 Aurora Labs Ltd. Opportunistic software updates during select operational modes
RU2678175C1 (ru) * 2018-03-16 2019-01-23 федеральное государственное бюджетное учреждение "Научно-исследовательский институт гриппа имени А.А. Смородинцева" Министерства здравоохранения Российской Федерации (ФГБУ "НИИ гриппа им. А.А. Смородинцева" Минздрава России) Рекомбинантный штамм вируса гриппа A/PR8/HK-NS80E85A, экспрессирующий фрагменты антигенов ESAT-6 и Ag85A M.tuberculosis, для получения векторной вакцины против туберкулеза
CN111979162B (zh) * 2019-05-22 2024-02-13 上海市公共卫生临床中心 重组卡介苗菌株、其制备方法和用途
EP4149529A1 (de) 2020-05-11 2023-03-22 Vakzine Projekt Management GmbH Vorbeugung von infektionskrankheiten durch modulation des immunsystems
WO2021228363A1 (en) 2020-05-11 2021-11-18 Vakzine Projekt Management Gmbh Prevention of infectious diseases by modulating the immune system
EP4122491A1 (de) 2021-07-22 2023-01-25 Vakzine Projekt Management GmbH Rekombinantes mikrobakterium als immunotherapeutisches mittel für die zweitlinientherapie eines blasenkarzinoms
JP2024530404A (ja) 2021-07-22 2024-08-21 セラム ライフ サイエンス ヨーロッパ ゲーエムベーハー 膀胱癌の第二選択療法のための免疫療法剤としての組換えマイコバクテリウム

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0902086A1 (de) * 1997-08-22 1999-03-17 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Tuberkolose Impfstoff
CN1798762B (zh) * 2003-04-23 2010-04-28 马普科技促进协会 效能提高的结核病疫苗

Also Published As

Publication number Publication date
KR20050114281A (ko) 2005-12-05
MXPA05011360A (es) 2005-11-28
US8545854B2 (en) 2013-10-01
PT1618128E (pt) 2010-10-13
BRPI0409789B1 (pt) 2018-10-16
ES2344698T3 (es) 2010-09-03
HK1091217A1 (en) 2007-01-12
RU2005136354A (ru) 2006-03-20
JP4662925B2 (ja) 2011-03-30
PL1618128T3 (pl) 2010-12-31
US20070134267A1 (en) 2007-06-14
EP1618128A1 (de) 2006-01-25
KR101101263B1 (ko) 2012-01-04
DE602004028000D1 (de) 2010-08-19
CN1798762B (zh) 2010-04-28
AU2004232485A1 (en) 2004-11-04
HRP20100395T1 (hr) 2010-09-30
CU23608A3 (es) 2010-12-08
UA91180C2 (ru) 2010-07-12
JP2007524367A (ja) 2007-08-30
CA2523084A1 (en) 2004-11-04
CA2523084C (en) 2012-09-04
CY1110793T1 (el) 2015-06-10
SI1618128T1 (sl) 2010-11-30
ZA200508276B (en) 2006-06-28
US20120027794A1 (en) 2012-02-02
US7988980B2 (en) 2011-08-02
BRPI0409789A (pt) 2006-05-30
WO2004094469A1 (en) 2004-11-04
EP1618128B1 (de) 2010-07-07
RU2342400C2 (ru) 2008-12-27
DK1618128T3 (da) 2010-10-18
CN1798762A (zh) 2006-07-05
BRPI0409789B8 (pt) 2021-05-25
AU2004232485B2 (en) 2009-11-26

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