ATE473238T1 - Tuberkulose vaccine mit verbesserter effizienz - Google Patents
Tuberkulose vaccine mit verbesserter effizienzInfo
- Publication number
- ATE473238T1 ATE473238T1 AT04729090T AT04729090T ATE473238T1 AT E473238 T1 ATE473238 T1 AT E473238T1 AT 04729090 T AT04729090 T AT 04729090T AT 04729090 T AT04729090 T AT 04729090T AT E473238 T1 ATE473238 T1 AT E473238T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- acid molecules
- improved efficiency
- tuberculosis vaccine
- present
- Prior art date
Links
- 229960002109 tuberculosis vaccine Drugs 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 150000007523 nucleic acids Chemical class 0.000 abstract 4
- 108010008038 Synthetic Vaccines Proteins 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 229940124551 recombinant vaccine Drugs 0.000 abstract 1
- 201000008827 tuberculosis Diseases 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46464403P | 2003-04-23 | 2003-04-23 | |
PCT/EP2004/004345 WO2004094469A1 (en) | 2003-04-23 | 2004-04-23 | Tuberculosis vaccine with improved efficacy |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE473238T1 true ATE473238T1 (de) | 2010-07-15 |
Family
ID=33310924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04729090T ATE473238T1 (de) | 2003-04-23 | 2004-04-23 | Tuberkulose vaccine mit verbesserter effizienz |
Country Status (24)
Country | Link |
---|---|
US (2) | US7988980B2 (de) |
EP (1) | EP1618128B1 (de) |
JP (1) | JP4662925B2 (de) |
KR (1) | KR101101263B1 (de) |
CN (1) | CN1798762B (de) |
AT (1) | ATE473238T1 (de) |
AU (1) | AU2004232485B2 (de) |
BR (1) | BRPI0409789B8 (de) |
CA (1) | CA2523084C (de) |
CU (1) | CU23608A3 (de) |
CY (1) | CY1110793T1 (de) |
DE (1) | DE602004028000D1 (de) |
DK (1) | DK1618128T3 (de) |
ES (1) | ES2344698T3 (de) |
HK (1) | HK1091217A1 (de) |
HR (1) | HRP20100395T1 (de) |
MX (1) | MXPA05011360A (de) |
PL (1) | PL1618128T3 (de) |
PT (1) | PT1618128E (de) |
RU (1) | RU2342400C2 (de) |
SI (1) | SI1618128T1 (de) |
UA (1) | UA91180C2 (de) |
WO (1) | WO2004094469A1 (de) |
ZA (1) | ZA200508276B (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1798762B (zh) * | 2003-04-23 | 2010-04-28 | 马普科技促进协会 | 效能提高的结核病疫苗 |
EP1649869A1 (de) * | 2004-10-21 | 2006-04-26 | Vakzine Projekt Management GmbH | Kombination von rekombinanten Mycobakterien und einem biologisch aktiven Agent als Vakzine |
DK1827504T3 (da) | 2004-12-01 | 2011-08-29 | Aeras Global Tb Vaccine Foundation | Rekombinante BCG-stammer med forøget evne til at undslippe fra endosomet |
WO2009089535A2 (en) * | 2008-01-11 | 2009-07-16 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Polypeptide vaccine and vaccination strategy against mycobacterium |
WO2011031139A1 (en) | 2009-09-09 | 2011-03-17 | Universiteit Utrecht Holding B.V. | An ataq protein or a part thereof as a vaccine |
SA110310855B1 (ar) | 2009-11-13 | 2014-09-16 | Laboratories Leti S L Unipersonal | استخدام مصدر l3 و/ أو l5 كلقاح أو كوسيلة تشخيصية لمرض طفيلي |
RU2586774C2 (ru) | 2010-08-27 | 2016-06-10 | Пантархей Байосайенс Б.В. | Иммунотерапевтический способ лечения рака простаты |
ES2685928T3 (es) | 2010-09-20 | 2018-10-15 | Vakzine Projekt Management Gmbh | Mycobacterium recombinante como vacuna para uso en seres humanos |
CA2817421C (en) | 2010-11-10 | 2020-04-14 | Laboratorios Leti, S.L. | Adjuvant derived from leishmania species |
SI2654783T1 (sl) * | 2010-12-21 | 2017-02-28 | Max-Planck-Gesellschaft zur Fourderung der Wissenschaften e.V. | Rekombinantni mycobacterium kot cepivo |
SG191331A1 (en) | 2010-12-21 | 2013-07-31 | Max Planck Gesellschaft | Determination of the efficacy of an anti-mycobacterial vaccination |
RU2520078C1 (ru) * | 2013-04-25 | 2014-06-20 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации (ФГБУ "НИИЭМ им. Н.Ф. Гамалеи" Минздрава России) | СПОСОБ ПОЛУЧЕНИЯ ИММУНОГЕННОЙ КОМПОЗИЦИИ НА ОСНОВЕ ГИБРИДНОГО БЕЛКА Ag85A-DBD И ДЕКСТРАНА, РЕКОМБИНАНТНАЯ ПЛАЗМИДА pAg85A-DBD, ШТАММ Escherichia coli [pREP4, pAg85A-DBD], ХИМЕРНЫЙ БЕЛОК Ag85A-DBD |
WO2016080830A2 (en) | 2014-11-18 | 2016-05-26 | Pantarhei Bioscience B.V. | Immunotherapeutic method for treating pancreatic cancer |
EP3090757A1 (de) * | 2015-05-04 | 2016-11-09 | Vakzine Projekt Management GmbH | Rekombinantes mycobakterium als immuntherapeutikum zur behandlung von krebs |
US20180256633A1 (en) | 2015-09-18 | 2018-09-13 | Rijksuniversiteit Groningen | Long chain inulin for stimulating an immune response |
KR101825439B1 (ko) * | 2016-04-15 | 2018-02-05 | 배재대학교 산학협력단 | 염산 처리에 의한 그람양성 박테리아 고스트의 제조 방법 |
WO2018184188A1 (en) * | 2017-04-07 | 2018-10-11 | Chengdu Yongan Pharmaceutical Co., Ltd. | RECOMBINANT BCG OVEREXPRESSING phoP-phoR |
US10387139B2 (en) * | 2017-07-25 | 2019-08-20 | Aurora Labs Ltd. | Opportunistic software updates during select operational modes |
RU2678175C1 (ru) * | 2018-03-16 | 2019-01-23 | федеральное государственное бюджетное учреждение "Научно-исследовательский институт гриппа имени А.А. Смородинцева" Министерства здравоохранения Российской Федерации (ФГБУ "НИИ гриппа им. А.А. Смородинцева" Минздрава России) | Рекомбинантный штамм вируса гриппа A/PR8/HK-NS80E85A, экспрессирующий фрагменты антигенов ESAT-6 и Ag85A M.tuberculosis, для получения векторной вакцины против туберкулеза |
CN111979162B (zh) * | 2019-05-22 | 2024-02-13 | 上海市公共卫生临床中心 | 重组卡介苗菌株、其制备方法和用途 |
EP4149529A1 (de) | 2020-05-11 | 2023-03-22 | Vakzine Projekt Management GmbH | Vorbeugung von infektionskrankheiten durch modulation des immunsystems |
WO2021228363A1 (en) | 2020-05-11 | 2021-11-18 | Vakzine Projekt Management Gmbh | Prevention of infectious diseases by modulating the immune system |
EP4122491A1 (de) | 2021-07-22 | 2023-01-25 | Vakzine Projekt Management GmbH | Rekombinantes mikrobakterium als immunotherapeutisches mittel für die zweitlinientherapie eines blasenkarzinoms |
JP2024530404A (ja) | 2021-07-22 | 2024-08-21 | セラム ライフ サイエンス ヨーロッパ ゲーエムベーハー | 膀胱癌の第二選択療法のための免疫療法剤としての組換えマイコバクテリウム |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0902086A1 (de) * | 1997-08-22 | 1999-03-17 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Tuberkolose Impfstoff |
CN1798762B (zh) * | 2003-04-23 | 2010-04-28 | 马普科技促进协会 | 效能提高的结核病疫苗 |
-
2004
- 2004-04-23 CN CN2004800106640A patent/CN1798762B/zh not_active Expired - Lifetime
- 2004-04-23 SI SI200431506T patent/SI1618128T1/sl unknown
- 2004-04-23 DK DK04729090.3T patent/DK1618128T3/da active
- 2004-04-23 WO PCT/EP2004/004345 patent/WO2004094469A1/en active Application Filing
- 2004-04-23 KR KR1020057020036A patent/KR101101263B1/ko active IP Right Grant
- 2004-04-23 PT PT04729090T patent/PT1618128E/pt unknown
- 2004-04-23 CA CA2523084A patent/CA2523084C/en not_active Expired - Lifetime
- 2004-04-23 RU RU2005136354/13A patent/RU2342400C2/ru active
- 2004-04-23 ES ES04729090T patent/ES2344698T3/es not_active Expired - Lifetime
- 2004-04-23 DE DE602004028000T patent/DE602004028000D1/de not_active Expired - Lifetime
- 2004-04-23 MX MXPA05011360A patent/MXPA05011360A/es active IP Right Grant
- 2004-04-23 EP EP04729090A patent/EP1618128B1/de not_active Expired - Lifetime
- 2004-04-23 AT AT04729090T patent/ATE473238T1/de active
- 2004-04-23 UA UAA200510351A patent/UA91180C2/ru unknown
- 2004-04-23 AU AU2004232485A patent/AU2004232485B2/en not_active Expired
- 2004-04-23 US US10/554,408 patent/US7988980B2/en active Active
- 2004-04-23 JP JP2006505250A patent/JP4662925B2/ja not_active Expired - Lifetime
- 2004-04-23 PL PL04729090T patent/PL1618128T3/pl unknown
- 2004-04-23 BR BRPI0409789A patent/BRPI0409789B8/pt active IP Right Grant
-
2005
- 2005-10-13 ZA ZA200508276A patent/ZA200508276B/en unknown
- 2005-10-26 CU CU20050206A patent/CU23608A3/es active IP Right Grant
-
2006
- 2006-10-27 HK HK06111864.4A patent/HK1091217A1/xx not_active IP Right Cessation
-
2010
- 2010-07-19 HR HR20100395T patent/HRP20100395T1/hr unknown
- 2010-09-16 CY CY20101100846T patent/CY1110793T1/el unknown
-
2011
- 2011-06-22 US US13/165,904 patent/US8545854B2/en not_active Expired - Lifetime
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