MX9701103A - Productos extracelulares abundantes y metodos para su produccion y uso. - Google Patents

Productos extracelulares abundantes y metodos para su produccion y uso.

Info

Publication number
MX9701103A
MX9701103A MX9701103A MX9701103A MX9701103A MX 9701103 A MX9701103 A MX 9701103A MX 9701103 A MX9701103 A MX 9701103A MX 9701103 A MX9701103 A MX 9701103A MX 9701103 A MX9701103 A MX 9701103A
Authority
MX
Mexico
Prior art keywords
extracellular products
vaccines
abundant extracellular
production
methods
Prior art date
Application number
MX9701103A
Other languages
English (en)
Other versions
MXPA97001103A (es
Inventor
Marcus A Horwitz
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of MX9701103A publication Critical patent/MX9701103A/es
Publication of MXPA97001103A publication Critical patent/MXPA97001103A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se presentan vacunas basadas en combinaciones de productos extracelulares mayormente abundantes de patogenos y métodos para su uso y produccion. Se seleccionan los productos extracelulares más prevalecientes o mayormente abundantes de un patogeno objetivo sin importar su inmunogenicidad molecular absoluta, y se utilizan como vacunas para estimular una respuesta inmune protectora en huéspedes mamíferos contra la infeccion subsecuente por el patogeno objetivo. Los productos extracelulares mayormente abundantes se pueden caracterizar y distinguir por sus secuencias de aminoácidos con terminal N respectivas. Ya que las vacunas pueden comprender diferentes combinaciones de productos extracelulares, la presente invencion proporciona composiciones inmunoterapéuticas efectivas de amplio rango. En adicion a otros agentes infecciosos, las vacunas así producidas se pueden utilizar para estimular una respuesta inmune efectiva contra patogenos intracelulares, y en particular Mycobacterium tuberculosis.
MXPA/A/1997/001103A 1994-08-12 1997-02-12 Productos extracelulares abundantes y metodos para su produccion y uso MXPA97001103A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28966794A 1994-08-12 1994-08-12
US289667 1994-08-12

Publications (2)

Publication Number Publication Date
MX9701103A true MX9701103A (es) 1998-10-31
MXPA97001103A MXPA97001103A (es) 1999-01-11

Family

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Also Published As

Publication number Publication date
WO1996005223A1 (en) 1996-02-22

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal