ATE355853T1 - Heterologer schutz, induziert durch immunisierung mit der invaplex-vakzine - Google Patents

Heterologer schutz, induziert durch immunisierung mit der invaplex-vakzine

Info

Publication number
ATE355853T1
ATE355853T1 AT02741716T AT02741716T ATE355853T1 AT E355853 T1 ATE355853 T1 AT E355853T1 AT 02741716 T AT02741716 T AT 02741716T AT 02741716 T AT02741716 T AT 02741716T AT E355853 T1 ATE355853 T1 AT E355853T1
Authority
AT
Austria
Prior art keywords
heterologue
immunization
protection induced
invaplex
invaplex vaccine
Prior art date
Application number
AT02741716T
Other languages
English (en)
Inventor
Edwin V Oaks
Kevin R Turbyfill
Original Assignee
Us Army
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Army filed Critical Us Army
Application granted granted Critical
Publication of ATE355853T1 publication Critical patent/ATE355853T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0283—Shigella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT02741716T 2001-05-18 2002-05-17 Heterologer schutz, induziert durch immunisierung mit der invaplex-vakzine ATE355853T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29215401P 2001-05-18 2001-05-18
US29249301P 2001-05-21 2001-05-21

Publications (1)

Publication Number Publication Date
ATE355853T1 true ATE355853T1 (de) 2007-03-15

Family

ID=26967184

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02741716T ATE355853T1 (de) 2001-05-18 2002-05-17 Heterologer schutz, induziert durch immunisierung mit der invaplex-vakzine

Country Status (9)

Country Link
US (1) US7258863B2 (de)
EP (1) EP1395283B1 (de)
JP (2) JP4510382B2 (de)
AT (1) ATE355853T1 (de)
AU (1) AU2002314793B2 (de)
CA (1) CA2447274C (de)
DE (1) DE60218662T2 (de)
DK (1) DK1395283T3 (de)
WO (1) WO2002094190A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004025144D1 (de) 2003-11-25 2010-03-04 Us Gov Sec Army Verwendung von shigella invaplex für den transportven nukleinsäuren durch säugetier-zellmembranen in vitro und in vivo
US7481997B1 (en) 2004-02-12 2009-01-27 Montana State University Snow mountain virus genome sequence, virus-like particles and methods of use
US20080124355A1 (en) 2006-09-22 2008-05-29 David Gordon Bermudes Live bacterial vaccines for viral infection prophylaxis or treatment
CA2563214A1 (en) * 2006-10-12 2008-04-12 Institut Pasteur Shigella ipad protein and its use as a potential vaccine against shigella infection
CN101711165B (zh) * 2007-03-27 2016-02-24 以沃尔特里德军事研究所的名义,由美国陆军部部长为代表的美国政府 人造侵袭素复合物
EP2197421A1 (de) * 2007-08-31 2010-06-23 Amgen, Inc Protein-formulierung in festem zustand
US8241623B1 (en) 2009-02-09 2012-08-14 David Bermudes Protease sensitivity expression system
US9597379B1 (en) 2010-02-09 2017-03-21 David Gordon Bermudes Protease inhibitor combination with therapeutic proteins including antibodies
US8771669B1 (en) 2010-02-09 2014-07-08 David Gordon Bermudes Immunization and/or treatment of parasites and infectious agents by live bacteria
US8524220B1 (en) 2010-02-09 2013-09-03 David Gordon Bermudes Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria
JP6045499B2 (ja) * 2010-10-27 2016-12-14 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 赤痢菌リポ多糖及び外膜タンパク質を含む免疫原性組成物
US9593339B1 (en) 2013-02-14 2017-03-14 David Gordon Bermudes Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
AU1199900A (en) * 1998-09-30 2000-04-17 Walter Reed Army Institute Of Research Use of purified invaplex from gram negative bacteria as a vaccine

Also Published As

Publication number Publication date
AU2002314793B2 (en) 2007-08-02
DE60218662D1 (de) 2007-04-19
JP5149242B2 (ja) 2013-02-20
WO2002094190A3 (en) 2003-12-11
JP2009197031A (ja) 2009-09-03
DE60218662T2 (de) 2007-11-08
EP1395283B1 (de) 2007-03-07
CA2447274C (en) 2013-11-12
DK1395283T3 (da) 2007-07-09
CA2447274A1 (en) 2002-11-28
US7258863B2 (en) 2007-08-21
EP1395283A4 (de) 2005-06-08
WO2002094190A2 (en) 2002-11-28
JP2004534762A (ja) 2004-11-18
US20020197276A1 (en) 2002-12-26
EP1395283A2 (de) 2004-03-10
JP4510382B2 (ja) 2010-07-21

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties