DK0754682T3 - Aminostilbazolderivat og lægemiddel - Google Patents
Aminostilbazolderivat og lægemiddelInfo
- Publication number
- DK0754682T3 DK0754682T3 DK95914513T DK95914513T DK0754682T3 DK 0754682 T3 DK0754682 T3 DK 0754682T3 DK 95914513 T DK95914513 T DK 95914513T DK 95914513 T DK95914513 T DK 95914513T DK 0754682 T3 DK0754682 T3 DK 0754682T3
- Authority
- DK
- Denmark
- Prior art keywords
- represents hydrogen
- drug
- hydroxy
- ring
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6825294 | 1994-04-06 | ||
| PCT/JP1995/000658 WO1995027699A1 (en) | 1994-04-06 | 1995-04-05 | Aminostilbazole derivative and medicine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0754682T3 true DK0754682T3 (da) | 2002-02-04 |
Family
ID=13368389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95914513T DK0754682T3 (da) | 1994-04-06 | 1995-04-05 | Aminostilbazolderivat og lægemiddel |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5972976A (show.php) |
| EP (1) | EP0754682B9 (show.php) |
| JP (1) | JP3080405B2 (show.php) |
| KR (1) | KR100293867B1 (show.php) |
| CN (1) | CN1053658C (show.php) |
| AT (1) | ATE207057T1 (show.php) |
| CA (1) | CA2187214C (show.php) |
| DE (1) | DE69523298T2 (show.php) |
| DK (1) | DK0754682T3 (show.php) |
| ES (1) | ES2165911T3 (show.php) |
| PT (1) | PT754682E (show.php) |
| RU (1) | RU2138482C1 (show.php) |
| TW (1) | TW308586B (show.php) |
| WO (1) | WO1995027699A1 (show.php) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2328719A1 (en) * | 1998-04-15 | 1999-10-21 | Hiroyoshi Hidaka | Method for in vivo detecting target protein gene by drug |
| ATE366114T1 (de) * | 1998-05-12 | 2007-07-15 | Greenville Hospital System | Verwendung von anti-prolaktin agentien zur behandlung von krebs |
| US6994283B1 (en) * | 1999-04-23 | 2006-02-07 | Nippon Shinyaku Co., Ltd. | Method for pulverizing to fine powder |
| US6521658B1 (en) | 1999-05-28 | 2003-02-18 | Abbott Laboratories | Cell proliferation inhibitors |
| MXPA02005866A (es) * | 1999-12-14 | 2002-10-23 | Nippon Shinyaku Co Ltd | Derivados de heterociclo y drogas. |
| JP2004359545A (ja) * | 2001-03-08 | 2004-12-24 | D Western Therapeutics Institute | 抗癌剤耐性克服剤 |
| KR100801121B1 (ko) * | 2001-04-10 | 2008-02-05 | 니뽄 신야쿠 가부시키가이샤 | 만성 관절 류마티즘 치료제 |
| EP1382335A4 (en) | 2001-04-26 | 2006-05-24 | Nippon Shinyaku Co Ltd | PHARMACEUTICAL PRODUCTS |
| US6951875B2 (en) * | 2001-10-29 | 2005-10-04 | Hoffmann-La Roche Inc. | Conjugated aromatic compounds with a pyridine substituent |
| FR2838437B1 (fr) * | 2002-04-11 | 2004-06-04 | Aventis Pharma Sa | Procedes de preparation de combretastatines |
| EP1547596A4 (en) * | 2002-09-06 | 2008-11-19 | Western Therapeutics Inst Inc | MEDICAL COMPOSITION AND METHOD FOR THE TREATMENT OF MALIGNANT TUMORS AND THE USE THEREOF |
| WO2006078941A2 (en) * | 2005-01-20 | 2006-07-27 | Sirtris Pharmaceuticals, Inc. | Novel sirtuin activating compounds and methods of use thereof |
| WO2007137196A2 (en) * | 2006-05-19 | 2007-11-29 | Threshold Pharmaceuticals, Inc. | Tubulin binding anti cancer compounds and prodrugs thereof |
| US20100198262A1 (en) * | 2009-01-30 | 2010-08-05 | Mckinley Laurence M | Axial offset bone fastener system |
| EP2986596A4 (en) * | 2013-04-19 | 2017-02-08 | The Board of Trustees of the University of Arkansas | Combretastatin analogs |
| BR122020005031B1 (pt) | 2013-12-13 | 2022-08-02 | Eurochem Agro Gmbh | Processo para preparação de ácido 2-(n-3,4-dimetilpirazol) succínico e solução alcalina aquosa de ácido 2-(n-3,4-dimetilpirazol) succínico |
| CA2940694A1 (en) | 2014-03-31 | 2015-10-08 | Board Of Trustees Of The University Of Arkansas | Disubstituted triazole analogs |
| DE102017201608A1 (de) | 2017-02-01 | 2018-08-02 | Eurochem Agro Gmbh | 3,4-Dimethylpyrazol enthaltende Mischung und ihre Verwendung |
| CN112110829B (zh) * | 2019-06-19 | 2023-08-01 | 复旦大学 | 一种能结合α-突触核蛋白聚集体的小分子化合物、其制备方法及其用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69129611T2 (de) * | 1990-08-20 | 1998-12-17 | Eisai Co., Ltd., Tokio/Tokyo | Sulfonamid-Derivate |
| JP2790926B2 (ja) * | 1990-08-20 | 1998-08-27 | エーザイ株式会社 | スルホンアミド誘導体 |
| JP2692467B2 (ja) * | 1991-12-09 | 1997-12-17 | ダイキン工業株式会社 | 空調制御装置の電力供給装置 |
| EP0570594B1 (en) * | 1991-12-10 | 1997-07-30 | Shionogi & Co., Ltd. | Hydroxamic acid derivative based on aromatic sulfonamide |
-
1995
- 1995-04-05 US US08/765,131 patent/US5972976A/en not_active Expired - Lifetime
- 1995-04-05 CA CA002187214A patent/CA2187214C/en not_active Expired - Lifetime
- 1995-04-05 EP EP95914513A patent/EP0754682B9/en not_active Expired - Lifetime
- 1995-04-05 KR KR1019960705560A patent/KR100293867B1/ko not_active Expired - Lifetime
- 1995-04-05 RU RU96121800A patent/RU2138482C1/ru active
- 1995-04-05 ES ES95914513T patent/ES2165911T3/es not_active Expired - Lifetime
- 1995-04-05 AT AT95914513T patent/ATE207057T1/de active
- 1995-04-05 PT PT95914513T patent/PT754682E/pt unknown
- 1995-04-05 DK DK95914513T patent/DK0754682T3/da active
- 1995-04-05 JP JP07526235A patent/JP3080405B2/ja not_active Expired - Lifetime
- 1995-04-05 WO PCT/JP1995/000658 patent/WO1995027699A1/ja not_active Ceased
- 1995-04-05 DE DE69523298T patent/DE69523298T2/de not_active Expired - Lifetime
- 1995-04-05 CN CN95192423A patent/CN1053658C/zh not_active Expired - Lifetime
- 1995-04-28 TW TW084104225A patent/TW308586B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0754682A4 (en) | 1998-03-04 |
| KR100293867B1 (ko) | 2001-09-17 |
| EP0754682B9 (en) | 2003-09-17 |
| CA2187214A1 (en) | 1995-10-19 |
| CA2187214C (en) | 2002-03-12 |
| CN1145066A (zh) | 1997-03-12 |
| PT754682E (pt) | 2002-03-28 |
| ES2165911T3 (es) | 2002-04-01 |
| RU2138482C1 (ru) | 1999-09-27 |
| JP3080405B2 (ja) | 2000-08-28 |
| WO1995027699A1 (en) | 1995-10-19 |
| MX9604540A (es) | 1997-09-30 |
| DE69523298T2 (de) | 2002-06-27 |
| EP0754682B1 (en) | 2001-10-17 |
| EP0754682A1 (en) | 1997-01-22 |
| ATE207057T1 (de) | 2001-11-15 |
| DE69523298D1 (de) | 2001-11-22 |
| KR970702253A (ko) | 1997-05-13 |
| TW308586B (show.php) | 1997-06-21 |
| US5972976A (en) | 1999-10-26 |
| CN1053658C (zh) | 2000-06-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0754682T3 (da) | Aminostilbazolderivat og lægemiddel | |
| ATE396988T1 (de) | Chinolin- und chianzolinderivate zur behandlung von tumoren | |
| NO992549L (no) | Sukkerforbindelse, geleringsmiddel og fremgangsmåte for fremstilling derav | |
| PT787726E (pt) | Novo composto, processo para a sua producao e agente tumoral | |
| PT918776E (pt) | Sintese total de acilfulvenos antitumorais | |
| DE3869907D1 (de) | Chinolincarbonsaeure-derivate. | |
| EA200300982A1 (ru) | Гетероциклические производные для лечения рака и других пролиферативных заболеваний | |
| ES8506629A1 (es) | Un procedimiento para preparar derivados de piridina | |
| ATE232528T1 (de) | Pyrimidinylpyrazolderivate | |
| ATE324362T1 (de) | Neue vinylbenzolderivate | |
| ATE248814T1 (de) | 16-ene-vitamin d derivate | |
| MY130817A (en) | Herbicides | |
| DE60307792D1 (de) | Hydroxylierte indirubinderivate | |
| FI915025A0 (fi) | 8-azabicyklo(3,2,1) oktylalkyltiazolidinoner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. | |
| ATE24915T1 (de) | Synergistin-derivate und ihre herstellung. | |
| NO951211D0 (no) | Ny 7-substituert oksa- eller azasteroidforbindelse | |
| FI935399L (fi) | N-substituerade azabicykloheptanderivat samt deras framstaellning och anvaendning |